George J. Augustine Lee Kong Chian School of Medicine Nanyang Technological University Biography Publications Institution JoVE Articles George J. Augustine has not added a biography. If you are George J. Augustine and would like to personalize this page please email our Author Liaison for assistance. Publications A Neuroprotective Role for MicroRNA MiR-1000 Mediated by Limiting Glutamate Excitotoxicity Nature Neuroscience. Feb, 2015 | Pubmed ID: 25643297 STIM2 Regulates PKA-dependent Phosphorylation and Trafficking of AMPARs Molecular Biology of the Cell. Jan, 2015 | Pubmed ID: 25609091 Protein Tyrosine Phosphatase Receptor Type R is Required for Purkinje Cell Responsiveness in Cerebellar Long-term Depression Molecular Brain. Jan, 2015 | Pubmed ID: 25571783 Presynaptic Nanodomains: a Tale of Two Synapses Frontiers in Cellular Neuroscience. 2014 | Pubmed ID: 25674049 Optogenetics Reveals a Role for Accumbal Medium Spiny Neurons Expressing Dopamine D2 Receptors in Cocaine-induced Behavioral Sensitization Frontiers in Behavioral Neuroscience. 2014 | Pubmed ID: 25352792 Optogenetic Activation of Presynaptic Inputs in Lateral Amygdala Forms Associative Fear Memory Learning & Memory (Cold Spring Harbor, N.Y.). Nov, 2014 | Pubmed ID: 25322798 Optogenetic Mapping of Cerebellar Inhibitory Circuitry Reveals Spatially Biased Coordination of Interneurons Via Electrical Synapses Cell Reports. Jun, 2014 | Pubmed ID: 24857665 Optogenetic Stimulation of the Auditory Pathway The Journal of Clinical Investigation. Mar, 2014 | Pubmed ID: 24509078 Precise Control of Movement Kinematics by Optogenetic Inhibition of Purkinje Cell Activity The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2014 | Pubmed ID: 24501371 Next-generation Transgenic Mice for Optogenetic Analysis of Neural Circuits Frontiers in Neural Circuits. 2013 | Pubmed ID: 24324405 Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-free Protein Engineering Automation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2013 | Pubmed ID: 24107961 In Vivo Optogenetic Tracing of Functional Corticocortical Connections Between Motor Forelimb Areas Frontiers in Neural Circuits. 2013 | Pubmed ID: 23554588 Light-emitting Channelrhodopsins for Combined Optogenetic and Chemical-genetic Control of Neurons PloS One. 2013 | Pubmed ID: 23544095 Probing the Function of Neuronal Populations: Combining Micromirror-based Optogenetic Photostimulation with Voltage-sensitive Dye Imaging Neuroscience Research. Jan, 2013 | Pubmed ID: 23254260 Optogenetically Induced Sleep Spindle Rhythms Alter Sleep Architectures in Mice Proceedings of the National Academy of Sciences of the United States of America. Dec, 2012 | Pubmed ID: 23169668 Calcium As a Trigger for Cerebellar Long-term Synaptic Depression Cerebellum (London, England). Sep, 2012 | Pubmed ID: 21975855 Imaging Synaptic Inhibition with the Genetically Encoded Chloride Indicator Clomeleon Cold Spring Harbor Protocols. Dec, 2011 | Pubmed ID: 22135666 Cell Type–specific Channelrhodopsin-2 Transgenic Mice for Optogenetic Dissection of Neural Circuitry Function Nature Methods. Sep, 2011 | Pubmed ID: 21985008 The Diffusional Properties of Dendrites Depend on the Density of Dendritic Spines The European Journal of Neuroscience. Aug, 2011 | Pubmed ID: 21771115 Optogenetic Probing of Functional Brain Circuitry Experimental Physiology. Jan, 2011 | Pubmed ID: 21056968 Channel-mediated Tonic GABA Release from Glia Science (New York, N.Y.). Nov, 2010 | Pubmed ID: 20929730 Progressive NKCC1-dependent Neuronal Chloride Accumulation During Neonatal Seizures The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2010 | Pubmed ID: 20810895 Synapsins Differentially Control Dopamine and Serotonin Release The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2010 | Pubmed ID: 20660258 Quantifying the Effects of Elastic Collisions and Non-covalent Binding on Glutamate Receptor Trafficking in the Post-synaptic Density PLoS Computational Biology. May, 2010 | Pubmed ID: 20485563 Transcranial Optogenetic Stimulation for Functional Mapping of the Motor Cortex Journal of Neuroscience Methods. May, 2009 | Pubmed ID: 19428535 Imaging Activity of Neuronal Populations with New Long-wavelength Voltage-sensitive Dyes Brain Cell Biology. Dec, 2008 | Pubmed ID: 19219551 Editorial: Hello, Goodbye Brain Cell Biology. Dec, 2008 | Pubmed ID: 19184439 Synapsin IIa Controls the Reserve Pool of Glutamatergic Synaptic Vesicles The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2008 | Pubmed ID: 18945891 Optogenetic Probes Brain Cell Biology. Aug, 2008 | Pubmed ID: 18941897 Improved Expression of Halorhodopsin for Light-induced Silencing of Neuronal Activity Brain Cell Biology. Aug, 2008 | Pubmed ID: 18931914 Imaging Synaptic Inhibition Throughout the Brain Via Genetically Targeted Clomeleon Brain Cell Biology. Aug, 2008 | Pubmed ID: 18850274 A Positive Feedback Signal Transduction Loop Determines Timing of Cerebellar Long-term Depression Neuron. Aug, 2008 | Pubmed ID: 18760697 Calcium Helps Neurons Identify Synaptic Targets During Development Neuron. Jul, 2008 | Pubmed ID: 18667145 Calcium Channel Modulation As an All-purpose Mechanism for Short-term Synaptic Plasticity Neuron. Jan, 2008 | Pubmed ID: 18215614 Chemical Two-photon Uncaging CSH Protocols. 2007 | Pubmed ID: 21356996 Ca2+ Requirements for Cerebellar Long-term Synaptic Depression: Role for a Postsynaptic Leaky Integrator Neuron. Jun, 2007 | Pubmed ID: 17553426 Kinetics of Complexin Binding to the SNARE Complex: Correcting Single Molecule FRET Measurements for Hidden Events Biophysical Journal. Sep, 2007 | Pubmed ID: 17513363 In Vivo Light-induced Activation of Neural Circuitry in Transgenic Mice Expressing Channelrhodopsin-2 Neuron. Apr, 2007 | Pubmed ID: 17442243 Bernard Katz, Quantal Transmitter Release and the Foundations of Presynaptic Physiology The Journal of Physiology. Feb, 2007 | Pubmed ID: 17068096 Brain Cell Technology: a Valuable New Resource for Novel Techniques Brain Cell Biology. Dec, 2006 | Pubmed ID: 18443910 Imaging Synaptic Inhibition in Transgenic Mice Expressing the Chloride Indicator, Clomeleon Brain Cell Biology. Dec, 2006 | Pubmed ID: 18398684 Synapsin II Negatively Regulates Catecholamine Release Brain Cell Biology. Jun, 2006 | Pubmed ID: 17957479 Anomalous Diffusion in Purkinje Cell Dendrites Caused by Spines Neuron. Nov, 2006 | Pubmed ID: 17114048 Cocaine Increases Dopamine Release by Mobilization of a Synapsin-dependent Reserve Pool The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2006 | Pubmed ID: 16554471 The Chloride Transporter Na(+)-K(+)-Cl- Cotransporter Isoform-1 Contributes to Intracellular Chloride Increases After in Vitro Ischemia The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2006 | Pubmed ID: 16452663 Two-photon Imaging Reveals Somatodendritic Chloride Gradient in Retinal ON-type Bipolar Cells Expressing the Biosensor Clomeleon Neuron. Jan, 2006 | Pubmed ID: 16387641 The Primordial, Blue-cone Color System of the Mouse Retina The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2005 | Pubmed ID: 15930394 Structural Domains Involved in the Regulation of Transmitter Release by Synapsins The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2005 | Pubmed ID: 15758176 Different Presynaptic Roles of Synapsins at Excitatory and Inhibitory Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Dec, 2004 | Pubmed ID: 15601943 Dual Roles of the C2B Domain of Synaptotagmin I in Synchronizing Ca2+-dependent Neurotransmitter Release The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2004 | Pubmed ID: 15456828 Synaptotagmin I Synchronizes Transmitter Release in Mouse Hippocampal Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2004 | Pubmed ID: 15240804 Molecular Determinants of Synapsin Targeting to Presynaptic Terminals The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2004 | Pubmed ID: 15071120 Local Calcium Signaling in Neurons Neuron. Oct, 2003 | Pubmed ID: 14556712 Eps15 Homology Domain-NPF Motif Interactions Regulate Clathrin Coat Assembly During Synaptic Vesicle Recycling The Journal of Biological Chemistry. Aug, 2003 | Pubmed ID: 12807910 Synaptic Vesicle Endocytosis: the Races, Places, and Molecular Faces Neuromolecular Medicine. 2002 | Pubmed ID: 12428806 Regulation of Neurotransmitter Release by Synapsin III The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2002 | Pubmed ID: 12040043 Differential Regulation of Exocytosis by Alpha- and Beta-SNAPs The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2002 | Pubmed ID: 11756488 גישת optogenetic להערכת יצירת קשרים עצביים במערכת Co-תרבות Colin T. E. Su*1, Su-In Yoon*2, Guillaume Marcy*1, Eunice W. M. Chin1, George J. Augustine2, Eyleen L. K. Goh1 1Neuroscience & Behavioral Disorders, Duke-NUS Graduate Medical School, 2Lee Kong Chian School of Medicine, Nanyang Technological University Biologie du développement
גישת optogenetic להערכת יצירת קשרים עצביים במערכת Co-תרבות Colin T. E. Su*1, Su-In Yoon*2, Guillaume Marcy*1, Eunice W. M. Chin1, George J. Augustine2, Eyleen L. K. Goh1 1Neuroscience & Behavioral Disorders, Duke-NUS Graduate Medical School, 2Lee Kong Chian School of Medicine, Nanyang Technological University Biologie du développement