Gonzalo Sanchez-Duffhues Dept. Cell Chemical Biology Leiden University Medical Center Biography Publications Institution JoVE Articles Gonzalo Sanchez-Duffhues has not added a biography. If you are Gonzalo Sanchez-Duffhues and would like to personalize this page please email our Author Liaison for assistance. Publications Exacerbated Inflammatory Signaling Underlies Aberrant Response to BMP9 in Pulmonary Arterial Hypertension Lung Endothelial Cells Angiogenesis. 11, 2020 | Pubmed ID: 32813135 Bone Morphogenetic Protein Receptors: Structure, Function and Targeting by Selective Small Molecule Kinase Inhibitors Bone. Sep, 2020 | Pubmed ID: 32522605 TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 32373613 Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas Cancer Cell. 03, 2020 | Pubmed ID: 32142668 Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva-Derived Endothelial Cells JBMR Plus. Nov, 2019 | Pubmed ID: 31768489 Generation of Fibrodysplasia Ossificans Progressiva and Control Integration Free IPSC Lines from Periodontal Ligament Fibroblasts Stem Cell Research. 12, 2019 | Pubmed ID: 31733439 Endothelial Colony Forming Cells As an Autologous Model to Study Endothelial Dysfunction in Patients with a Bicuspid Aortic Valve International Journal of Molecular Sciences. Jul, 2019 | Pubmed ID: 31269711 Inflammation Induces Endothelial-to-mesenchymal Transition and Promotes Vascular Calcification Through Downregulation of BMPR2 The Journal of Pathology. 03, 2019 | Pubmed ID: 30430573 Bone Morphogenetic Protein Receptor Signal Transduction in Human Disease The Journal of Pathology. 01, 2019 | Pubmed ID: 30246251 The Therapeutic Potential of Targeting the Endothelial-to-mesenchymal Transition Angiogenesis. 02, 2019 | Pubmed ID: 30076548 Endothelial-to-mesenchymal Transition in Cardiovascular Diseases: Developmental Signaling Pathways Gone Awry Developmental Dynamics : an Official Publication of the American Association of Anatomists. 03, 2018 | Pubmed ID: 28891150 TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases International Journal of Molecular Sciences. Oct, 2017 | Pubmed ID: 29039786 Involvement of Inflammation and Its Related MicroRNAs in Hepatocellular Carcinoma Oncotarget. Mar, 2017 | Pubmed ID: 27888618 Towards a Cure for Fibrodysplasia Ossificans Progressiva Annals of Translational Medicine. Oct, 2016 | Pubmed ID: 27867996 Emerging Regulators of BMP Bioavailability Bone. Dec, 2016 | Pubmed ID: 26825814 In Brief: Endothelial-to-mesenchymal Transition The Journal of Pathology. Feb, 2016 | Pubmed ID: 26446982 Signal Transduction: Gain of Activin Turns Muscle into Bone Current Biology : CB. Dec, 2015 | Pubmed ID: 26654374 Bone Morphogenetic Protein 6 and Oxidized Low-density Lipoprotein Synergistically Recruit Osteogenic Differentiation in Endothelial Cells Cardiovascular Research. Nov, 2015 | Pubmed ID: 26410368 Bone Morphogenetic Protein Signaling in Bone Homeostasis Bone. Nov, 2015 | Pubmed ID: 26051467 Osteochondromas in Fibrodysplasia Ossificans Progressiva: a Widespread Trait with a Streaking but Overlooked Appearance when Arising at Femoral Bone End Rheumatology International. Oct, 2015 | Pubmed ID: 26049728 SLUG is Expressed in Endothelial Cells Lacking Primary Cilia to Promote Cellular Calcification Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2015 | Pubmed ID: 25633317 Clinical Utility Gene Card For: Fibrodysplasia Ossificans Progressiva European Journal of Human Genetics : EJHG. Oct, 2015 | Pubmed ID: 25604857 Antisense-oligonucleotide Mediated Exon Skipping in Activin-receptor-like Kinase 2: Inhibiting the Receptor That is Overactive in Fibrodysplasia Ossificans Progressiva PloS One. 2013 | Pubmed ID: 23861958 BMP Signaling in Vascular Diseases FEBS Letters. Jul, 2012 | Pubmed ID: 22710160 TGF-β medieret endotel til mesenchymal overgang (EndMT) og funktionel vurdering af EndMT-effektorer ved hjælp af CRISPR/Cas9-genredigering Jin Ma1,2, Gerard van der Zon1,2, Gonzalo Sanchez-Duffhues1, Peter ten Dijke1,2 1Dept. Cell Chemical Biology, Leiden University Medical Center, 2Oncode Institute, Leiden University Medical Center JoVE 62198 Biologie
TGF-β medieret endotel til mesenchymal overgang (EndMT) og funktionel vurdering af EndMT-effektorer ved hjælp af CRISPR/Cas9-genredigering Jin Ma1,2, Gerard van der Zon1,2, Gonzalo Sanchez-Duffhues1, Peter ten Dijke1,2 1Dept. Cell Chemical Biology, Leiden University Medical Center, 2Oncode Institute, Leiden University Medical Center JoVE 62198 Biologie