Graham C. Burdge Human Development & Health Academic Unit, Faculty of Medicine University of Southampton Biography Publications Institution JoVE Articles Graham C. Burdge has not added a biography. If you are Graham C. Burdge and would like to personalize this page please email our Author Liaison for assistance. Publications Differential Pathways to Adult Metabolic Dysfunction Following Poor Nutrition at Two Critical Developmental Periods in Sheep PloS One. 2014 | Pubmed ID: 24603546 Effect of Sex Hormones on N-3 Polyunsaturated Fatty Acid Biosynthesis in HepG2 Cells and in Human Primary Hepatocytes Prostaglandins, Leukotrienes, and Essential Fatty Acids. Feb-Mar, 2014 | Pubmed ID: 24411721 Environment-physiology, Diet Quality and Energy Balance: The Influence of Early Life Nutrition on Future Energy Balance Physiology & Behavior. Jan, 2014 | Pubmed ID: 24394988 Fatty Acids and Epigenetics Current Opinion in Clinical Nutrition and Metabolic Care. Mar, 2014 | Pubmed ID: 24322369 Breast Cancer and the Importance of Early Life Nutrition Cancer Treatment and Research. 2014 | Pubmed ID: 24114486 Improving Articles Reporting Nutritional Studies of Extracts in the British Journal of Nutrition and in the Journal of Nutritional Science The British Journal of Nutrition. Feb, 2014 | Pubmed ID: 23919933 Site Distribution at the Edge of the Palaeolithic World: a Nutritional Niche Approach PloS One. 2013 | Pubmed ID: 24339935 DHA Supplementation During Pregnancy and DNA Methylation in Cord Blood Leukocytes The American Journal of Clinical Nutrition. Dec, 2013 | Pubmed ID: 24259358 Increasing Numbers of Citations and Higher Impact Factor in 2012: the British Journal of Nutrition Continues to Show Steady Improvement The British Journal of Nutrition. Oct, 2013 | Pubmed ID: 23953924 Tissue-specific 5' Heterogeneity of PPARα Transcripts and Their Differential Regulation by Leptin PloS One. 2013 | Pubmed ID: 23825665 Non-imprinted Epigenetics in Fetal and Postnatal Development and Growth Nestlé Nutrition Institute Workshop Series. 2013 | Pubmed ID: 23502139 Maternal Fat Intake in Rats Alters 20:4n-6 and 22:6n-3 Status and the Epigenetic Regulation of Fads2 in Offspring Liver The Journal of Nutritional Biochemistry. Jul, 2013 | Pubmed ID: 23107313 Folic Acid Supplementation in Pregnancy: Are There Devils in the Detail? The British Journal of Nutrition. Dec, 2012 | Pubmed ID: 23046900 Epigenetic Mechanisms Linking Early Nutrition to Long Term Health Best Practice & Research. Clinical Endocrinology & Metabolism. Oct, 2012 | Pubmed ID: 22980048 Epigenetics: Are There Implications for Personalised Nutrition? Current Opinion in Clinical Nutrition and Metabolic Care. Sep, 2012 | Pubmed ID: 22878237 Vascular Dysfunction Induced in Offspring by Maternal Dietary Fat Involves Altered Arterial Polyunsaturated Fatty Acid Biosynthesis PloS One. 2012 | Pubmed ID: 22509311 Increasing the Folic Acid Content of Maternal or Post-weaning Diets Induces Differential Changes in Phosphoenolpyruvate Carboxykinase MRNA Expression and Promoter Methylation in Rats The British Journal of Nutrition. Sep, 2012 | Pubmed ID: 22136740 Enteral Feeding Therapy for Newly Diagnosed Pediatric Crohn's Disease: a Double-blind Randomized Controlled Trial with Two Years Follow-up Inflammatory Bowel Diseases. Feb, 2012 | Pubmed ID: 21425210 The Effect of Nutrition During Early Life on the Epigenetic Regulation of Transcription and Implications for Human Diseases Journal of Nutrigenetics and Nutrigenomics. 2011 | Pubmed ID: 22353662 Progressive, Transgenerational Changes in Offspring Phenotype and Epigenotype Following Nutritional Transition PloS One. 2011 | Pubmed ID: 22140567 Dietary Protein Restriction During F0 Pregnancy in Rats Induces Transgenerational Changes in the Hepatic Transcriptome in Female Offspring PloS One. 2011 | Pubmed ID: 21750721 Umbilical Venous-arterial Plasma Composition Differences Suggest Differential Incorporation of Fatty Acids in NEFA and Cholesteryl Ester Pools The British Journal of Nutrition. Aug, 2011 | Pubmed ID: 21521544 Epigenetic Gene Promoter Methylation at Birth is Associated with Child's Later Adiposity Diabetes. May, 2011 | Pubmed ID: 21471513 Developmental Plasticity and Developmental Origins of Non-communicable Disease: Theoretical Considerations and Epigenetic Mechanisms Progress in Biophysics and Molecular Biology. Jul, 2011 | Pubmed ID: 21219925 Polyunsaturated Fatty Acid Intakes and α-linolenic Acid Metabolism The American Journal of Clinical Nutrition. Mar, 2011 | Pubmed ID: 21191139 Diet, Nutrition and Modulation of Genomic Expression in Fetal Origins of Adult Disease Journal of Nutrigenetics and Nutrigenomics. 2010 | Pubmed ID: 21474951 Bridging the Gap Between Epigenetics Research and Nutritional Public Health Interventions Genome Medicine. 2010 | Pubmed ID: 21067534 Effect of Sex and Dietary Fat Intake on the Fatty Acid Composition of Phospholipids and Triacylglycerol in Rat Heart Prostaglandins, Leukotrienes, and Essential Fatty Acids. Oct-Dec, 2010 | Pubmed ID: 20719489 Diet, Nutrition and Modulation of Genomic Expression in Fetal Origins of Adult Disease World Review of Nutrition and Dietetics. 2010 | Pubmed ID: 20436253 Nutrition, Epigenetics, and Developmental Plasticity: Implications for Understanding Human Disease Annual Review of Nutrition. Aug, 2010 | Pubmed ID: 20415585 Maternal Protein Restriction with or Without Folic Acid Supplementation During Pregnancy Alters the Hepatic Transcriptome in Adult Male Rats The British Journal of Nutrition. Jun, 2010 | Pubmed ID: 20211039 The Polyunsaturated Fatty Acid Composition of Hepatic and Plasma Lipids Differ by Both Sex and Dietary Fat Intake in Rats The Journal of Nutrition. Feb, 2010 | Pubmed ID: 20007335 Maternal High-fat Feeding Primes Steatohepatitis in Adult Mice Offspring, Involving Mitochondrial Dysfunction and Altered Lipogenesis Gene Expression Hepatology (Baltimore, Md.). Dec, 2009 | Pubmed ID: 19816994 Antiretroviral Therapy with or Without Protease Inhibitors Impairs Postprandial TAG Hydrolysis in HIV-infected Men The British Journal of Nutrition. Oct, 2009 | Pubmed ID: 19480729 Folic Acid Supplementation During the Juvenile-pubertal Period in Rats Modifies the Phenotype and Epigenotype Induced by Prenatal Nutrition The Journal of Nutrition. Jun, 2009 | Pubmed ID: 19339705 Acute Consumption of Fish Oil Improves Postprandial VLDL Profiles in Healthy Men Aged 50-65 Years The British Journal of Nutrition. Jul, 2009 | Pubmed ID: 19138437 Nutrition in Early Life, and Risk of Cancer and Metabolic Disease: Alternative Endings in an Epigenetic Tale? The British Journal of Nutrition. Mar, 2009 | Pubmed ID: 19079817 Physical Inactivity Differentially Alters Dietary Oleate and Palmitate Trafficking Diabetes. Feb, 2009 | Pubmed ID: 19017764 Gender Differences in the N-3 Fatty Acid Content of Tissues The Proceedings of the Nutrition Society. Feb, 2008 | Pubmed ID: 18234128 Feeding Pregnant Rats a Protein-restricted Diet Persistently Alters the Methylation of Specific Cytosines in the Hepatic PPAR Alpha Promoter of the Offspring The British Journal of Nutrition. Aug, 2008 | Pubmed ID: 18186951 The Nature of the Growth Pattern and of the Metabolic Response to Fasting in the Rat Are Dependent Upon the Dietary Protein and Folic Acid Intakes of Their Pregnant Dams and Post-weaning Fat Consumption The British Journal of Nutrition. Mar, 2008 | Pubmed ID: 17761015 Tissue-specific Stable Isotope Measurements of Postprandial Lipid Metabolism in Familial Combined Hyperlipidaemia Atherosclerosis. Mar, 2008 | Pubmed ID: 17466309 Metabolic Plasticity During Mammalian Development is Directionally Dependent on Early Nutritional Status Proceedings of the National Academy of Sciences of the United States of America. Jul, 2007 | Pubmed ID: 17646663 Induction of Altered Epigenetic Regulation of the Hepatic Glucocorticoid Receptor in the Offspring of Rats Fed a Protein-restricted Diet During Pregnancy Suggests That Reduced DNA Methyltransferase-1 Expression is Involved in Impaired DNA Methylation and Changes in Histone Modifications The British Journal of Nutrition. Jun, 2007 | Pubmed ID: 17433129 Epigenetic Mechanisms and the Mismatch Concept of the Developmental Origins of Health and Disease Pediatric Research. May, 2007 | Pubmed ID: 17413851 Epigenetic Regulation of Transcription: a Mechanism for Inducing Variations in Phenotype (fetal Programming) by Differences in Nutrition During Early Life? The British Journal of Nutrition. Jun, 2007 | Pubmed ID: 17381976 Dietary Protein Restriction of Pregnant Rats in the F0 Generation Induces Altered Methylation of Hepatic Gene Promoters in the Adult Male Offspring in the F1 and F2 Generations The British Journal of Nutrition. Mar, 2007 | Pubmed ID: 17313703 Dietary Fatty Acids Make a Rapid and Substantial Contribution to VLDL-triacylglycerol in the Fed State American Journal of Physiology. Endocrinology and Metabolism. Mar, 2007 | Pubmed ID: 17090753 Dietary Alpha-linolenic Acid and Health-related Outcomes: a Metabolic Perspective Nutrition Research Reviews. Jun, 2006 | Pubmed ID: 19079874 Differences in Maternal Protein Intake in Pregnant Rats Alone Alter the Docosahexaenoic Acid Concentration in the Fetal and Adult Offspring Metabolism: Clinical and Experimental. Oct, 2006 | Pubmed ID: 16979417 Lack of Effect of Meal Fatty Acid Composition on Postprandial Lipid, Glucose and Insulin Responses in Men and Women Aged 50-65 Years Consuming Their Habitual Diets The British Journal of Nutrition. Sep, 2006 | Pubmed ID: 16925854 Homocysteine: a Role in Fetal Programming? The British Journal of Nutrition. Sep, 2006 | Pubmed ID: 16925844 Polyunsaturated Fatty Acid Concentrations in Young Men and Women Consuming Their Habitual Diets The British Journal of Nutrition. Jul, 2006 | Pubmed ID: 16869996 Effects of Dairy Products Naturally Enriched with Cis-9,trans-11 Conjugated Linoleic Acid on the Blood Lipid Profile in Healthy Middle-aged Men The American Journal of Clinical Nutrition. Apr, 2006 | Pubmed ID: 16600923 Variation in [U-13C] Alpha Linolenic Acid Absorption, Beta-oxidation and Conversion to Docosahexaenoic Acid in the Pre-term Infant Fed a DHA-enriched Formula Pediatric Research. Feb, 2006 | Pubmed ID: 16439591 Docosahexaenoic Acid is Selectively Enriched in Plasma Phospholipids During Pregnancy in Trinidadian Women--results of a Pilot Study Reproduction, Nutrition, Development. Jan-Feb, 2006 | Pubmed ID: 16438916 Conversion of Alpha-linolenic Acid to Longer-chain Polyunsaturated Fatty Acids in Human Adults Reproduction, Nutrition, Development. Sep-Oct, 2005 | Pubmed ID: 16188209 Incorporation of Cis-9, Trans-11 Conjugated Linoleic Acid and Vaccenic Acid (trans-11 18 : 1) into Plasma and Leucocyte Lipids in Healthy Men Consuming Dairy Products Naturally Enriched in These Fatty Acids The British Journal of Nutrition. Aug, 2005 | Pubmed ID: 16115358 The Effects of Conjugated Linoleic Acid on Human Health-related Outcomes The Proceedings of the Nutrition Society. May, 2005 | Pubmed ID: 15960862 Dietary Protein Restriction of Pregnant Rats Induces and Folic Acid Supplementation Prevents Epigenetic Modification of Hepatic Gene Expression in the Offspring The Journal of Nutrition. Jun, 2005 | Pubmed ID: 15930441 Plasma Cytokine Response During the Postprandial Period: a Potential Causal Process in Vascular Disease? The British Journal of Nutrition. Jan, 2005 | Pubmed ID: 15705218 Selective Changes to Phosphatidylcholine and Phosphatidylethanolamine Molecular Species in the Developing Fetal Guinea Pig Liver and Plasma Reproduction, Nutrition, Development. Nov-Dec, 2004 | Pubmed ID: 15762301 Effects of Cis-9,trans-11 and Trans-10,cis-12 Conjugated Linoleic Acid on Immune Cell Function in Healthy Humans The American Journal of Clinical Nutrition. Dec, 2004 | Pubmed ID: 15585778 The Effect of Dietary Supplementation with Linoleic Acid to Late Gestation Ewes on the Fatty Acid Composition of Maternal and Fetal Plasma and Tissues and the Synthetic Capacity of the Placenta for 2-series Prostaglandins Biochimica Et Biophysica Acta. Nov, 2004 | Pubmed ID: 15522830 Opposing Effects of Cis-9,trans-11 and Trans-10,cis-12 Conjugated Linoleic Acid on Blood Lipids in Healthy Humans The American Journal of Clinical Nutrition. Sep, 2004 | Pubmed ID: 15321800 Peripheral Blood Mononuclear Cell Fatty Acid Composition and Inflammatory Mediator Production in Adult Crohn's Disease Clinical Nutrition (Edinburgh, Scotland). Aug, 2004 | Pubmed ID: 15297102 Incorporation of Cis-9,trans-11 or Trans-10,cis-12 Conjugated Linoleic Acid into Plasma and Cellular Lipids in Healthy Men Journal of Lipid Research. Apr, 2004 | Pubmed ID: 14754909 Premenopausal Advantages in Postprandial Lipid Metabolism Are Lost in Women with Type 2 Diabetes Diabetes Care. Dec, 2003 | Pubmed ID: 14633809 Prostaglandin E2 Production and T Cell Function After Fish-oil Supplementation: Response to Antioxidant Cosupplementation The American Journal of Clinical Nutrition. Sep, 2003 | Pubmed ID: 12936918 Selective Partitioning of Dietary Fatty Acids into the VLDL TG Pool in the Early Postprandial Period Journal of Lipid Research. Nov, 2003 | Pubmed ID: 12923230 Inhibition of Tumour Necrosis Factor-alpha and Interleukin 6 Production by Mononuclear Cells Following Dietary Fish-oil Supplementation in Healthy Men and Response to Antioxidant Co-supplementation The British Journal of Nutrition. Aug, 2003 | Pubmed ID: 12908901 Effect of Reduced Maternal Protein Intake in Pregnancy in the Rat on the Fatty Acid Composition of Brain, Liver, Plasma, Heart and Lung Phospholipids of the Offspring After Weaning The British Journal of Nutrition. Aug, 2003 | Pubmed ID: 12908895 Effect of Altered Dietary N-3 Fatty Acid Intake Upon Plasma Lipid Fatty Acid Composition, Conversion of [13C]alpha-linolenic Acid to Longer-chain Fatty Acids and Partitioning Towards Beta-oxidation in Older Men The British Journal of Nutrition. Aug, 2003 | Pubmed ID: 12908891 UK Food Standards Agency Alpha-linolenic Acid Workshop Report The British Journal of Nutrition. Nov, 2002 | Pubmed ID: 12425738 Conversion of Alpha-linolenic Acid to Eicosapentaenoic, Docosapentaenoic and Docosahexaenoic Acids in Young Women The British Journal of Nutrition. Oct, 2002 | Pubmed ID: 12323090 Effect of Reduced Dietary Protein Intake on Hepatic and Plasma Essential Fatty Acid Concentrations in the Adult Female Rat: Effect of Pregnancy and Consequences for Accumulation of Arachidonic and Docosahexaenoic Acids in Fetal Liver and Brain The British Journal of Nutrition. Oct, 2002 | Pubmed ID: 12323087 Eicosapentaenoic and Docosapentaenoic Acids Are the Principal Products of Alpha-linolenic Acid Metabolism in Young Men* The British Journal of Nutrition. Oct, 2002 | Pubmed ID: 12323085 Regulation of Dietary Fatty Acid Entrapment in Subcutaneous Adipose Tissue and Skeletal Muscle Diabetes. Sep, 2002 | Pubmed ID: 12196459 Bruk av gasskromatografi å analysere kompositorisk Endringer av fettsyrer i Rat levervev under graviditet Helena L. Fisk1, Annette L. West1, Caroline E. Childs1, Graham C. Burdge1, Philip C. Calder1 1Human Development & Health Academic Unit, Faculty of Medicine, University of Southampton JoVE 51445 Chimie
Bruk av gasskromatografi å analysere kompositorisk Endringer av fettsyrer i Rat levervev under graviditet Helena L. Fisk1, Annette L. West1, Caroline E. Childs1, Graham C. Burdge1, Philip C. Calder1 1Human Development & Health Academic Unit, Faculty of Medicine, University of Southampton JoVE 51445 Chimie