Greg Horwitz Physiology & Biophysics University of Washington Biography Publications Institution JoVE Articles Greg Horwitz Greg Horwitz is a Professor in the Department of Physiology and Biophysics at the University of Washington and serves as the Chief of the Neuroscience Division at the Washington National Primate Research Center. He received his undergraduate degree from Harvard University and a Ph.D. from Stanford University.Research in the Horwitz lab focuses on the neurobiological basis of vision and visually guided behavior. Of particular interest are the mechanisms that limit the sensation of flicker and the circuitry by which signals from the cone photoreceptors are combined in the visual cortex. Recently completed projects in Dr. Horwitz's laboratory have refined new genetic tools for the manipulation of neural activity in non-human primates, and ongoing projects continue to extend this toolkit. A critical component of this work is the validation of new viral vectors that target specific cell types. Publications Windows and Periscopes into Primate Behavior Cell Reports. Jul, 2021 | Pubmed ID: 34289362 Temporal Filtering of Luminance and Chromaticity in Macaque Visual Cortex IScience. Jun, 2021 | Pubmed ID: 34189430 Functional Enhancer Elements Drive Subclass-selective Expression from Mouse to Primate Neocortex Cell Reports. Mar, 2021 | Pubmed ID: 33789096 Spatial Receptive Field Structure of Double-opponent Cells in Macaque V1 Journal of Neurophysiology. 03, 2021 | Pubmed ID: 33405995 Signals Related to Color in the Early Visual Cortex Annual Review of Vision Science. 09, 2020 | Pubmed ID: 32936735 Viral Vectors for Neural Circuit Mapping and Recent Advances in Trans-synaptic Anterograde Tracers Neuron. 09, 2020 | Pubmed ID: 32755550 Fast and Reversible Neural Inactivation in Macaque Cortex by Optogenetic Stimulation of GABAergic Neurons ELife. 05, 2020 | Pubmed ID: 32452766 Temporal Information Loss in the Macaque Early Visual System PLoS Biology. 01, 2020 | Pubmed ID: 31971946 Primate Optogenetics: Progress and Prognosis Proceedings of the National Academy of Sciences of the United States of America. Dec, 2019 | Pubmed ID: 31871196 Model of Parafoveal Chromatic and Luminance Temporal Contrast Sensitivity of Humans and Monkeys Journal of Vision. 11, 2018 | Pubmed ID: 30383213 Focal Optogenetic Suppression in Macaque Area MT Biases Direction Discrimination and Decision Confidence, but Only Transiently ELife. 07, 2018 | Pubmed ID: 30051817 Dethroning the Fano Factor: A Flexible, Model-Based Approach to Partitioning Neural Variability Neural Computation. 04, 2018 | Pubmed ID: 29381442 Measurements of Neuronal Color Tuning: Procedures, Pitfalls, and Alternatives Vision Research. 10, 2018 | Pubmed ID: 29133032 Selective Optogenetic Control of Purkinje Cells in Monkey Cerebellum Neuron. Jul, 2017 | Pubmed ID: 28648497 AAV-mediated Delivery of Optogenetic Constructs to the Macaque Brain Triggers Humoral Immune Responses Journal of Neurophysiology. 05, 2017 | Pubmed ID: 28202570 Strategies for Targeting Primate Neural Circuits with Viral Vectors Journal of Neurophysiology. 07, 2016 | Pubmed ID: 27052579 Chromatic Detection from Cone Photoreceptors to V1 Neurons to Behavior in Rhesus Monkeys Journal of Vision. Month, 2015 | Pubmed ID: 26523737 What Studies of Macaque Monkeys Have Told Us About Human Color Vision Neuroscience. Jun, 2015 | Pubmed ID: 25445192 Spectral Sensitivity Differences Between Rhesus Monkeys and Humans: Implications for Neurophysiology Journal of Neurophysiology. Dec, 2014 | Pubmed ID: 25253473 Object-centered Shifts of Receptive Field Positions in Monkey Primary Visual Cortex Current Biology : CB. Jul, 2014 | Pubmed ID: 25017208 V1 Mechanisms Underlying Chromatic Contrast Detection Journal of Neurophysiology. May, 2013 | Pubmed ID: 23446689 Saccadic Eye Movements Evoked by Optogenetic Activation of Primate V1 Nature Neuroscience. Oct, 2012 | Pubmed ID: 22941109 Nonlinear Analysis of Macaque V1 Color Tuning Reveals Cardinal Directions for Cortical Color Processing Nature Neuroscience. Jun, 2012 | Pubmed ID: 22581184 Effects of Microsaccades on Contrast Detection and V1 Responses in Macaques Journal of Vision. Mar, 2011 | Pubmed ID: 21378110 Advances in Color Science: from Retina to Behavior The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2010 | Pubmed ID: 21068298 Injektioner af AAV-vektorer til optogenetik i bedøvet og vågen adfærd ikke-menneskelig primathjerne Yoshiko Kojima1,2, Jonathan T. Ting2,3,4, Robijanto Soetedjo2,4, Shane D. Gibson2,4, Gregory D. Horwitz2,4 1Dept. of Otolaryngology - Head and Neck Surgery, University of Washington, 2Washington National Primate Research Center, University of Washington, 3Allen Institute for Brain Science, 4Dept. of Physiology & Biophysics, University of Washington JoVE 62546 Neurosciences
Injektioner af AAV-vektorer til optogenetik i bedøvet og vågen adfærd ikke-menneskelig primathjerne Yoshiko Kojima1,2, Jonathan T. Ting2,3,4, Robijanto Soetedjo2,4, Shane D. Gibson2,4, Gregory D. Horwitz2,4 1Dept. of Otolaryngology - Head and Neck Surgery, University of Washington, 2Washington National Primate Research Center, University of Washington, 3Allen Institute for Brain Science, 4Dept. of Physiology & Biophysics, University of Washington JoVE 62546 Neurosciences