Gregory J. Morton Department of Medicine University of Washington Biography Publications Institution JoVE Articles Gregory J. Morton has not added a biography. If you are Gregory J. Morton and would like to personalize this page please email our Author Liaison for assistance. Publications The Role of Vasodilator-stimulated Phosphoprotein (VASP) in the Control of Hepatic Gluconeogenic Gene Expression PloS One. 2019 | Pubmed ID: 31017943 The Central Fibroblast Growth Factor Receptor/beta Klotho System: Comprehensive Mapping in Mus Musculus and Comparisons to Nonhuman Primate and Human Samples Using an Automated in Situ Hybridization Platform The Journal of Comparative Neurology. Aug, 2019 | Pubmed ID: 30809795 The Hypothalamic Arcuate Nucleus-Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1 Diabetes. 05, 2019 | Pubmed ID: 30796029 Glucoregulatory Responses to Hypothalamic Preoptic Area Cooling Brain Research. 05, 2019 | Pubmed ID: 30610874 Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain Diabetes. 03, 2019 | Pubmed ID: 30523024 Distinct Neuronal Projections From the Hypothalamic Ventromedial Nucleus Mediate Glycemic and Behavioral Effects Diabetes. 12, 2018 | Pubmed ID: 30257978 Leptin Regulation of Core Body Temperature Involves Mechanisms Independent of the Thyroid Axis American Journal of Physiology. Endocrinology and Metabolism. 10, 2018 | Pubmed ID: 29944392 In Uncontrolled Diabetes, Hyperglucagonemia and Ketosis Result From Deficient Leptin Action in the Parabrachial Nucleus Endocrinology. 04, 2018 | Pubmed ID: 29438473 Androgen Receptor Deficiency in Monocytes/macrophages Does Not Alter Adiposity or Glucose Homeostasis in Male Mice Asian Journal of Andrology. May-Jun, 2018 | Pubmed ID: 29205180 Chronic Hindbrain Administration of Oxytocin is Sufficient to Elicit Weight Loss in Diet-induced Obese Rats American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Oct, 2017 | Pubmed ID: 28747407 How Should We Think About the Role of the Brain in Glucose Homeostasis and Diabetes? Diabetes. 07, 2017 | Pubmed ID: 28603139 Response to Molecular Metabolism. 04, 2017 | Pubmed ID: 28377869 Metabolically Distinct Weight Loss by 10,12 CLA and Caloric Restriction Highlight the Importance of Subcutaneous White Adipose Tissue for Glucose Homeostasis in Mice PloS One. 2017 | Pubmed ID: 28245284 Sex Differences in Microglial CX3CR1 Signalling Determine Obesity Susceptibility in Mice Nature Communications. 02, 2017 | Pubmed ID: 28223698 Evidence That the Sympathetic Nervous System Elicits Rapid, Coordinated, and Reciprocal Adjustments of Insulin Secretion and Insulin Sensitivity During Cold Exposure Diabetes. 04, 2017 | Pubmed ID: 28115396 Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity Diabetes. 04, 2017 | Pubmed ID: 28073831 Physiological Role for Leptin in the Control of Thermal Conductance Molecular Metabolism. Oct, 2016 | Pubmed ID: 27689002 Central Injection of Fibroblast Growth Factor 1 Induces Sustained Remission of Diabetic Hyperglycemia in Rodents Nature Medicine. 07, 2016 | Pubmed ID: 27213816 Functional Identification of a Neurocircuit Regulating Blood Glucose Proceedings of the National Academy of Sciences of the United States of America. Apr, 2016 | Pubmed ID: 27001850 The Role of Leptin in Diabetes: Metabolic Effects Diabetologia. May, 2016 | Pubmed ID: 26969486 Chronic CNS Oxytocin Signaling Preferentially Induces Fat Loss in High-fat Diet-fed Rats by Enhancing Satiety Responses and Increasing Lipid Utilization American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Apr, 2016 | Pubmed ID: 26791828 Evidence Against Hypothalamic-pituitary-adrenal Axis Suppression in the Antidiabetic Action of Leptin The Journal of Clinical Investigation. Nov, 2015 | Pubmed ID: 26529250 Glucose Intolerance Induced by Blockade of Central FGF Receptors is Linked to an Acute Stress Response Molecular Metabolism. Aug, 2015 | Pubmed ID: 26266088 In Vivo Structure-function Studies of Human Hepatic Lipase: the Catalytic Function Rescues the Lean Phenotype of HL-deficient (hl-/-) Mice Physiological Reports. Apr, 2015 | Pubmed ID: 25862097 Leptin Signaling is Required for Adaptive Changes in Food Intake, but Not Energy Expenditure, in Response to Different Thermal Conditions PloS One. 2015 | Pubmed ID: 25756181 Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia Diabetes. Jul, 2015 | Pubmed ID: 25633417 Chronic Oxytocin Administration Inhibits Food Intake, Increases Energy Expenditure, and Produces Weight Loss in Fructose-fed Obese Rhesus Monkeys American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2015 | Pubmed ID: 25540103 Role of Melanocortin Signaling in Neuroendocrine and Metabolic Actions of Leptin in Male Rats with Uncontrolled Diabetes Endocrinology. Nov, 2014 | Pubmed ID: 25137027 Genetic Determinants of Atherosclerosis, Obesity, and Energy Balance in Consomic Mice Mammalian Genome : Official Journal of the International Mammalian Genome Society. Dec, 2014 | Pubmed ID: 25001233 Hindbrain Oxytocin Receptors Contribute to the Effects of Circulating Oxytocin on Food Intake in Male Rats Endocrinology. Aug, 2014 | Pubmed ID: 24877632 Neurobiology of Food Intake in Health and Disease Nature Reviews. Neuroscience. Jun, 2014 | Pubmed ID: 24840801 Carbohydrate Feeding Dissociates the Postprandial FGF19 Response from Circulating Bile Acid Levels in Humans The Journal of Clinical Endocrinology and Metabolism. Feb, 2014 | Pubmed ID: 24297792 Is There Evidence That Estrogen Therapy Promotes Weight Maintenance Via Effects on Leptin? Menopause (New York, N.Y.). Apr, 2014 | Pubmed ID: 24149922 Cooperation Between Brain and Islet in Glucose Homeostasis and Diabetes Nature. Nov, 2013 | Pubmed ID: 24201279 Rapid Glutamate Release in the Mediobasal Hypothalamus Accompanies Feeding and is Exaggerated by an Obesogenic Food Molecular Metabolism. 2013 | Pubmed ID: 24199157 FGF19 Action in the Brain Induces Insulin-independent Glucose Lowering The Journal of Clinical Investigation. Nov, 2013 | Pubmed ID: 24084738 Molecular and Functional Analysis of Human β-defensin 3 Action at Melanocortin Receptors Chemistry & Biology. Jun, 2013 | Pubmed ID: 23790489 Leptin Action in the Ventromedial Hypothalamic Nucleus is Sufficient, but Not Necessary, to Normalize Diabetic Hyperglycemia Endocrinology. Sep, 2013 | Pubmed ID: 23782941 In Uncontrolled Diabetes, Thyroid Hormone and Sympathetic Activators Induce Thermogenesis Without Increasing Glucose Uptake in Brown Adipose Tissue American Journal of Physiology. Endocrinology and Metabolism. Apr, 2013 | Pubmed ID: 23384771 BDNF Action in the Brain Attenuates Diabetic Hyperglycemia Via Insulin-independent Inhibition of Hepatic Glucose Production Diabetes. May, 2013 | Pubmed ID: 23274899 Leptin, Diabetes, and the Brain Indian Journal of Endocrinology and Metabolism. Dec, 2012 | Pubmed ID: 23565487 Acutely Decreased Thermoregulatory Energy Expenditure or Decreased Activity Energy Expenditure Both Acutely Reduce Food Intake in Mice PloS One. 2012 | Pubmed ID: 22936977 Obesity is Associated with Hypothalamic Injury in Rodents and Humans The Journal of Clinical Investigation. Jan, 2012 | Pubmed ID: 22201683 Peripheral Oxytocin Suppresses Food Intake and Causes Weight Loss in Diet-induced Obese Rats American Journal of Physiology. Endocrinology and Metabolism. Jan, 2012 | Pubmed ID: 22008455 Endothelial NO/cGMP/VASP Signaling Attenuates Kupffer Cell Activation and Hepatic Insulin Resistance Induced by High-fat Feeding Diabetes. Nov, 2011 | Pubmed ID: 21911751 Subcutaneous Administration of Leptin Normalizes Fasting Plasma Glucose in Obese Type 2 Diabetic UCD-T2DM Rats Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21873226 Leptin and the Central Nervous System Control of Glucose Metabolism Physiological Reviews. Apr, 2011 | Pubmed ID: 21527729 A Novel Rodent Model That Mimics the Metabolic Sequelae of Obese Craniopharyngioma Patients Pediatric Research. Mar, 2011 | Pubmed ID: 21372758 Leptin Activates a Novel CNS Mechanism for Insulin-independent Normalization of Severe Diabetic Hyperglycemia Endocrinology. Feb, 2011 | Pubmed ID: 21159853 Identification of a Physiological Role for Leptin in the Regulation of Ambulatory Activity and Wheel Running in Mice American Journal of Physiology. Endocrinology and Metabolism. Feb, 2011 | Pubmed ID: 21062956 Standard Operating Procedures for Describing and Performing Metabolic Tests of Glucose Homeostasis in Mice Disease Models & Mechanisms. Sep-Oct, 2010 | Pubmed ID: 20713647 Assessment of Feeding Behavior in Laboratory Mice Cell Metabolism. Jul, 2010 | Pubmed ID: 20620991 A New Oxytocin-saporin Cytotoxin for Lesioning Oxytocin-receptive Neurons in the Rat Hindbrain Endocrinology. Sep, 2010 | Pubmed ID: 20610562 Leptin Deficiency Causes Insulin Resistance Induced by Uncontrolled Diabetes Diabetes. Jul, 2010 | Pubmed ID: 20424233 Identification of Body Fat Mass As a Major Determinant of Metabolic Rate in Mice Diabetes. Jul, 2010 | Pubmed ID: 20413511 Central Administration of Interleukin-4 Exacerbates Hypothalamic Inflammation and Weight Gain During High-fat Feeding American Journal of Physiology. Endocrinology and Metabolism. Jul, 2010 | Pubmed ID: 20371733 Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats Diabetes. Jul, 2010 | Pubmed ID: 20357365 Mice Lacking Hepatic Lipase Are Lean and Protected Against Diet-induced Obesity and Hepatic Steatosis Endocrinology. Mar, 2010 | Pubmed ID: 20056822 Hypothalamic Leptin Signaling Regulates Hepatic Insulin Sensitivity Via a Neurocircuit Involving the Vagus Nerve Endocrinology. Oct, 2009 | Pubmed ID: 19574396 The Action of Leptin in the Ventral Tegmental Area to Decrease Food Intake is Dependent on Jak-2 Signaling American Journal of Physiology. Endocrinology and Metabolism. Jul, 2009 | Pubmed ID: 19435852 Hypothalamic Proinflammatory Lipid Accumulation, Inflammation, and Insulin Resistance in Rats Fed a High-fat Diet American Journal of Physiology. Endocrinology and Metabolism. May, 2009 | Pubmed ID: 19116375 Forebrain Melanocortin Signaling Enhances the Hindbrain Satiety Response to CCK-8 American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2009 | Pubmed ID: 19109369 Vascular Inflammation, Insulin Resistance, and Reduced Nitric Oxide Production Precede the Onset of Peripheral Insulin Resistance Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2008 | Pubmed ID: 18772497 Deficiency of TNFalpha Converting Enzyme (TACE/ADAM17) Causes a Lean, Hypermetabolic Phenotype in Mice Endocrinology. Dec, 2008 | Pubmed ID: 18687778 Signal Transducer and Activator of Transcription-3 is Required in Hypothalamic Agouti-related Protein/neuropeptide Y Neurons for Normal Energy Homeostasis Endocrinology. Jul, 2008 | Pubmed ID: 18403487 Hypothalamic Leptin Regulation of Energy Homeostasis and Glucose Metabolism The Journal of Physiology. Sep, 2007 | Pubmed ID: 17584844 Central Interleukin-1 (IL1) Signaling is Required for Pharmacological, but Not Physiological, Effects of Leptin on Energy Balance Brain Research. May, 2007 | Pubmed ID: 17320056 Thermoregulatory and Metabolic Defects in Huntington's Disease Transgenic Mice Implicate PGC-1alpha in Huntington's Disease Neurodegeneration Cell Metabolism. Nov, 2006 | Pubmed ID: 17055784 Insulin Action in the Brain Contributes to Glucose Lowering During Insulin Treatment of Diabetes Cell Metabolism. Jan, 2006 | Pubmed ID: 16399506 Leptin Regulates Insulin Sensitivity Via Phosphatidylinositol-3-OH Kinase Signaling in Mediobasal Hypothalamic Neurons Cell Metabolism. Dec, 2005 | Pubmed ID: 16330326 Effects of Hypothalamic Neurodegeneration on Energy Balance PLoS Biology. Dec, 2005 | Pubmed ID: 16296893 Leptin Inhibits Hypothalamic Npy and Agrp Gene Expression Via a Mechanism That Requires Phosphatidylinositol 3-OH-kinase Signaling American Journal of Physiology. Endocrinology and Metabolism. Dec, 2005 | Pubmed ID: 16046456 Leptin Action in the Forebrain Regulates the Hindbrain Response to Satiety Signals The Journal of Clinical Investigation. Mar, 2005 | Pubmed ID: 15711637 Increased Hypothalamic Melanin Concentrating Hormone Gene Expression During Energy Restriction Involves a Melanocortin-independent, Estrogen-sensitive Mechanism Peptides. Apr, 2004 | Pubmed ID: 15165723 Neuropeptide Y is Required for Hyperphagic Feeding in Response to Neuroglucopenia Endocrinology. Jul, 2004 | Pubmed ID: 15064281 Arcuate Nucleus-specific Leptin Receptor Gene Therapy Attenuates the Obesity Phenotype of Koletsky (fa(k)/fa(k)) Rats Endocrinology. May, 2003 | Pubmed ID: 12697710 גישה סטריאו-טיאו-טסטרואקטיבית מסתגלת לטכניקות רב-תכליתיות במדעי המוח Chelsea L. Faber1, Miles E. Matsen1, Thomas H. Meek1, Jordan E. Krull1, Gregory J. Morton1 1Department of Medicine, University of Washington JoVE 60965 Neurosciences
גישה סטריאו-טיאו-טסטרואקטיבית מסתגלת לטכניקות רב-תכליתיות במדעי המוח Chelsea L. Faber1, Miles E. Matsen1, Thomas H. Meek1, Jordan E. Krull1, Gregory J. Morton1 1Department of Medicine, University of Washington JoVE 60965 Neurosciences