Gregory J. Morton Department of Medicine University of Washington Biography Publications Institution JoVE Articles Gregory J. Morton has not added a biography. If you are Gregory J. Morton and would like to personalize this page please email our Author Liaison for assistance. Publications The Role of Vasodilator-stimulated Phosphoprotein (VASP) in the Control of Hepatic Gluconeogenic Gene Expression PloS One. 2019 | Pubmed ID: 31017943 The Central Fibroblast Growth Factor Receptor/beta Klotho System: Comprehensive Mapping in Mus Musculus and Comparisons to Nonhuman Primate and Human Samples Using an Automated in Situ Hybridization Platform The Journal of Comparative Neurology. Aug, 2019 | Pubmed ID: 30809795 The Hypothalamic Arcuate Nucleus-Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1 Diabetes. 05, 2019 | Pubmed ID: 30796029 Glucoregulatory Responses to Hypothalamic Preoptic Area Cooling Brain Research. 05, 2019 | Pubmed ID: 30610874 Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain Diabetes. 03, 2019 | Pubmed ID: 30523024 Distinct Neuronal Projections From the Hypothalamic Ventromedial Nucleus Mediate Glycemic and Behavioral Effects Diabetes. 12, 2018 | Pubmed ID: 30257978 Leptin Regulation of Core Body Temperature Involves Mechanisms Independent of the Thyroid Axis American Journal of Physiology. Endocrinology and Metabolism. 10, 2018 | Pubmed ID: 29944392 In Uncontrolled Diabetes, Hyperglucagonemia and Ketosis Result From Deficient Leptin Action in the Parabrachial Nucleus Endocrinology. 04, 2018 | Pubmed ID: 29438473 Androgen Receptor Deficiency in Monocytes/macrophages Does Not Alter Adiposity or Glucose Homeostasis in Male Mice Asian Journal of Andrology. May-Jun, 2018 | Pubmed ID: 29205180 Chronic Hindbrain Administration of Oxytocin is Sufficient to Elicit Weight Loss in Diet-induced Obese Rats American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Oct, 2017 | Pubmed ID: 28747407 How Should We Think About the Role of the Brain in Glucose Homeostasis and Diabetes? Diabetes. 07, 2017 | Pubmed ID: 28603139 Response to Molecular Metabolism. 04, 2017 | Pubmed ID: 28377869 Metabolically Distinct Weight Loss by 10,12 CLA and Caloric Restriction Highlight the Importance of Subcutaneous White Adipose Tissue for Glucose Homeostasis in Mice PloS One. 2017 | Pubmed ID: 28245284 Sex Differences in Microglial CX3CR1 Signalling Determine Obesity Susceptibility in Mice Nature Communications. 02, 2017 | Pubmed ID: 28223698 Evidence That the Sympathetic Nervous System Elicits Rapid, Coordinated, and Reciprocal Adjustments of Insulin Secretion and Insulin Sensitivity During Cold Exposure Diabetes. 04, 2017 | Pubmed ID: 28115396 Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity Diabetes. 04, 2017 | Pubmed ID: 28073831 Physiological Role for Leptin in the Control of Thermal Conductance Molecular Metabolism. Oct, 2016 | Pubmed ID: 27689002 Central Injection of Fibroblast Growth Factor 1 Induces Sustained Remission of Diabetic Hyperglycemia in Rodents Nature Medicine. 07, 2016 | Pubmed ID: 27213816 Functional Identification of a Neurocircuit Regulating Blood Glucose Proceedings of the National Academy of Sciences of the United States of America. Apr, 2016 | Pubmed ID: 27001850 The Role of Leptin in Diabetes: Metabolic Effects Diabetologia. May, 2016 | Pubmed ID: 26969486 Chronic CNS Oxytocin Signaling Preferentially Induces Fat Loss in High-fat Diet-fed Rats by Enhancing Satiety Responses and Increasing Lipid Utilization American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Apr, 2016 | Pubmed ID: 26791828 Evidence Against Hypothalamic-pituitary-adrenal Axis Suppression in the Antidiabetic Action of Leptin The Journal of Clinical Investigation. Nov, 2015 | Pubmed ID: 26529250 Glucose Intolerance Induced by Blockade of Central FGF Receptors is Linked to an Acute Stress Response Molecular Metabolism. Aug, 2015 | Pubmed ID: 26266088 In Vivo Structure-function Studies of Human Hepatic Lipase: the Catalytic Function Rescues the Lean Phenotype of HL-deficient (hl-/-) Mice Physiological Reports. Apr, 2015 | Pubmed ID: 25862097 Leptin Signaling is Required for Adaptive Changes in Food Intake, but Not Energy Expenditure, in Response to Different Thermal Conditions PloS One. 2015 | Pubmed ID: 25756181 Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia Diabetes. Jul, 2015 | Pubmed ID: 25633417 Chronic Oxytocin Administration Inhibits Food Intake, Increases Energy Expenditure, and Produces Weight Loss in Fructose-fed Obese Rhesus Monkeys American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2015 | Pubmed ID: 25540103 Role of Melanocortin Signaling in Neuroendocrine and Metabolic Actions of Leptin in Male Rats with Uncontrolled Diabetes Endocrinology. Nov, 2014 | Pubmed ID: 25137027 Genetic Determinants of Atherosclerosis, Obesity, and Energy Balance in Consomic Mice Mammalian Genome : Official Journal of the International Mammalian Genome Society. Dec, 2014 | Pubmed ID: 25001233 Hindbrain Oxytocin Receptors Contribute to the Effects of Circulating Oxytocin on Food Intake in Male Rats Endocrinology. Aug, 2014 | Pubmed ID: 24877632 Neurobiology of Food Intake in Health and Disease Nature Reviews. Neuroscience. Jun, 2014 | Pubmed ID: 24840801 Carbohydrate Feeding Dissociates the Postprandial FGF19 Response from Circulating Bile Acid Levels in Humans The Journal of Clinical Endocrinology and Metabolism. Feb, 2014 | Pubmed ID: 24297792 Is There Evidence That Estrogen Therapy Promotes Weight Maintenance Via Effects on Leptin? Menopause (New York, N.Y.). Apr, 2014 | Pubmed ID: 24149922 Cooperation Between Brain and Islet in Glucose Homeostasis and Diabetes Nature. Nov, 2013 | Pubmed ID: 24201279 Rapid Glutamate Release in the Mediobasal Hypothalamus Accompanies Feeding and is Exaggerated by an Obesogenic Food Molecular Metabolism. 2013 | Pubmed ID: 24199157 FGF19 Action in the Brain Induces Insulin-independent Glucose Lowering The Journal of Clinical Investigation. Nov, 2013 | Pubmed ID: 24084738 Molecular and Functional Analysis of Human β-defensin 3 Action at Melanocortin Receptors Chemistry & Biology. Jun, 2013 | Pubmed ID: 23790489 Leptin Action in the Ventromedial Hypothalamic Nucleus is Sufficient, but Not Necessary, to Normalize Diabetic Hyperglycemia Endocrinology. Sep, 2013 | Pubmed ID: 23782941 In Uncontrolled Diabetes, Thyroid Hormone and Sympathetic Activators Induce Thermogenesis Without Increasing Glucose Uptake in Brown Adipose Tissue American Journal of Physiology. Endocrinology and Metabolism. Apr, 2013 | Pubmed ID: 23384771 BDNF Action in the Brain Attenuates Diabetic Hyperglycemia Via Insulin-independent Inhibition of Hepatic Glucose Production Diabetes. May, 2013 | Pubmed ID: 23274899 Leptin, Diabetes, and the Brain Indian Journal of Endocrinology and Metabolism. Dec, 2012 | Pubmed ID: 23565487 Acutely Decreased Thermoregulatory Energy Expenditure or Decreased Activity Energy Expenditure Both Acutely Reduce Food Intake in Mice PloS One. 2012 | Pubmed ID: 22936977 Obesity is Associated with Hypothalamic Injury in Rodents and Humans The Journal of Clinical Investigation. Jan, 2012 | Pubmed ID: 22201683 Peripheral Oxytocin Suppresses Food Intake and Causes Weight Loss in Diet-induced Obese Rats American Journal of Physiology. Endocrinology and Metabolism. Jan, 2012 | Pubmed ID: 22008455 Endothelial NO/cGMP/VASP Signaling Attenuates Kupffer Cell Activation and Hepatic Insulin Resistance Induced by High-fat Feeding Diabetes. Nov, 2011 | Pubmed ID: 21911751 Subcutaneous Administration of Leptin Normalizes Fasting Plasma Glucose in Obese Type 2 Diabetic UCD-T2DM Rats Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21873226 Leptin and the Central Nervous System Control of Glucose Metabolism Physiological Reviews. Apr, 2011 | Pubmed ID: 21527729 A Novel Rodent Model That Mimics the Metabolic Sequelae of Obese Craniopharyngioma Patients Pediatric Research. Mar, 2011 | Pubmed ID: 21372758 Leptin Activates a Novel CNS Mechanism for Insulin-independent Normalization of Severe Diabetic Hyperglycemia Endocrinology. Feb, 2011 | Pubmed ID: 21159853 Identification of a Physiological Role for Leptin in the Regulation of Ambulatory Activity and Wheel Running in Mice American Journal of Physiology. Endocrinology and Metabolism. Feb, 2011 | Pubmed ID: 21062956 Standard Operating Procedures for Describing and Performing Metabolic Tests of Glucose Homeostasis in Mice Disease Models & Mechanisms. Sep-Oct, 2010 | Pubmed ID: 20713647 Assessment of Feeding Behavior in Laboratory Mice Cell Metabolism. Jul, 2010 | Pubmed ID: 20620991 A New Oxytocin-saporin Cytotoxin for Lesioning Oxytocin-receptive Neurons in the Rat Hindbrain Endocrinology. Sep, 2010 | Pubmed ID: 20610562 Leptin Deficiency Causes Insulin Resistance Induced by Uncontrolled Diabetes Diabetes. Jul, 2010 | Pubmed ID: 20424233 Identification of Body Fat Mass As a Major Determinant of Metabolic Rate in Mice Diabetes. Jul, 2010 | Pubmed ID: 20413511 Central Administration of Interleukin-4 Exacerbates Hypothalamic Inflammation and Weight Gain During High-fat Feeding American Journal of Physiology. Endocrinology and Metabolism. Jul, 2010 | Pubmed ID: 20371733 Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats Diabetes. Jul, 2010 | Pubmed ID: 20357365 Mice Lacking Hepatic Lipase Are Lean and Protected Against Diet-induced Obesity and Hepatic Steatosis Endocrinology. Mar, 2010 | Pubmed ID: 20056822 Hypothalamic Leptin Signaling Regulates Hepatic Insulin Sensitivity Via a Neurocircuit Involving the Vagus Nerve Endocrinology. Oct, 2009 | Pubmed ID: 19574396 The Action of Leptin in the Ventral Tegmental Area to Decrease Food Intake is Dependent on Jak-2 Signaling American Journal of Physiology. Endocrinology and Metabolism. Jul, 2009 | Pubmed ID: 19435852 Hypothalamic Proinflammatory Lipid Accumulation, Inflammation, and Insulin Resistance in Rats Fed a High-fat Diet American Journal of Physiology. Endocrinology and Metabolism. May, 2009 | Pubmed ID: 19116375 Forebrain Melanocortin Signaling Enhances the Hindbrain Satiety Response to CCK-8 American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Mar, 2009 | Pubmed ID: 19109369 Vascular Inflammation, Insulin Resistance, and Reduced Nitric Oxide Production Precede the Onset of Peripheral Insulin Resistance Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2008 | Pubmed ID: 18772497 Deficiency of TNFalpha Converting Enzyme (TACE/ADAM17) Causes a Lean, Hypermetabolic Phenotype in Mice Endocrinology. Dec, 2008 | Pubmed ID: 18687778 Signal Transducer and Activator of Transcription-3 is Required in Hypothalamic Agouti-related Protein/neuropeptide Y Neurons for Normal Energy Homeostasis Endocrinology. Jul, 2008 | Pubmed ID: 18403487 Hypothalamic Leptin Regulation of Energy Homeostasis and Glucose Metabolism The Journal of Physiology. Sep, 2007 | Pubmed ID: 17584844 Central Interleukin-1 (IL1) Signaling is Required for Pharmacological, but Not Physiological, Effects of Leptin on Energy Balance Brain Research. May, 2007 | Pubmed ID: 17320056 Thermoregulatory and Metabolic Defects in Huntington's Disease Transgenic Mice Implicate PGC-1alpha in Huntington's Disease Neurodegeneration Cell Metabolism. Nov, 2006 | Pubmed ID: 17055784 Insulin Action in the Brain Contributes to Glucose Lowering During Insulin Treatment of Diabetes Cell Metabolism. Jan, 2006 | Pubmed ID: 16399506 Leptin Regulates Insulin Sensitivity Via Phosphatidylinositol-3-OH Kinase Signaling in Mediobasal Hypothalamic Neurons Cell Metabolism. Dec, 2005 | Pubmed ID: 16330326 Effects of Hypothalamic Neurodegeneration on Energy Balance PLoS Biology. Dec, 2005 | Pubmed ID: 16296893 Leptin Inhibits Hypothalamic Npy and Agrp Gene Expression Via a Mechanism That Requires Phosphatidylinositol 3-OH-kinase Signaling American Journal of Physiology. Endocrinology and Metabolism. Dec, 2005 | Pubmed ID: 16046456 Leptin Action in the Forebrain Regulates the Hindbrain Response to Satiety Signals The Journal of Clinical Investigation. Mar, 2005 | Pubmed ID: 15711637 Increased Hypothalamic Melanin Concentrating Hormone Gene Expression During Energy Restriction Involves a Melanocortin-independent, Estrogen-sensitive Mechanism Peptides. Apr, 2004 | Pubmed ID: 15165723 Neuropeptide Y is Required for Hyperphagic Feeding in Response to Neuroglucopenia Endocrinology. Jul, 2004 | Pubmed ID: 15064281 Arcuate Nucleus-specific Leptin Receptor Gene Therapy Attenuates the Obesity Phenotype of Koletsky (fa(k)/fa(k)) Rats Endocrinology. May, 2003 | Pubmed ID: 12697710 Abordagem estereotática angular adaptável para técnicas versáteis de neurociência Chelsea L. Faber1, Miles E. Matsen1, Thomas H. Meek1, Jordan E. Krull1, Gregory J. Morton1 1Department of Medicine, University of Washington JoVE 60965 Neurosciences
Abordagem estereotática angular adaptável para técnicas versáteis de neurociência Chelsea L. Faber1, Miles E. Matsen1, Thomas H. Meek1, Jordan E. Krull1, Gregory J. Morton1 1Department of Medicine, University of Washington JoVE 60965 Neurosciences