Howard Crawford Department of Molecular and Cellular Physiology University of Michigan Biography Publications Institution JoVE Articles Howard Crawford has not added a biography. If you are Howard Crawford and would like to personalize this page please email our Author Liaison for assistance. Publications Hiding in Plain Sight Science (New York, N.Y.). 06, 2019 | Pubmed ID: 31221844 Myeloid Cell-Derived HB-EGF Drives Tissue Recovery After Pancreatitis Cellular and Molecular Gastroenterology and Hepatology. May, 2019 | Pubmed ID: 31125624 ATDC is Required for the Initiation of KRAS-induced Pancreatic Tumorigenesis Genes & Development. Jun, 2019 | Pubmed ID: 31048544 Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer Cell Metabolism. Jun, 2019 | Pubmed ID: 30827862 Signaling Networks That Control Cellular Plasticity in Pancreatic Tumorigenesis, Progression, and Metastasis Gastroenterology. 05, 2019 | Pubmed ID: 30716326 The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice Cellular and Molecular Gastroenterology and Hepatology. 2019 | Pubmed ID: 30510993 Epithelial-Stromal Interactions in Pancreatic Cancer Annual Review of Physiology. Feb, 2019 | Pubmed ID: 30418798 Spatial and Phenotypic Immune Profiling of Metastatic Colon Cancer JCI Insight. 11, 2018 | Pubmed ID: 30429368 STAT3 is a Master Regulator of Epithelial Identity and KRAS-driven Tumorigenesis Genes & Development. 09, 2018 | Pubmed ID: 30135074 HNF1A is a Novel Oncogene That Regulates Human Pancreatic Cancer Stem Cell Properties ELife. 08, 2018 | Pubmed ID: 30074477 MYC Regulates Ductal-neuroendocrine Lineage Plasticity in Pancreatic Ductal Adenocarcinoma Associated with Poor Outcome and Chemoresistance Nature Communications. 11, 2017 | Pubmed ID: 29170413 Epithelial-Myeloid Cell Crosstalk Regulates Acinar Cell Plasticity and Pancreatic Remodeling in Mice ELife. 10, 2017 | Pubmed ID: 28980940 Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis Cellular and Molecular Gastroenterology and Hepatology. Jan, 2017 | Pubmed ID: 28090569 PDX1 Dynamically Regulates Pancreatic Ductal Adenocarcinoma Initiation and Maintenance Genes & Development. 12, 2016 | Pubmed ID: 28087712 NRF2 Promotes Tumor Maintenance by Modulating MRNA Translation in Pancreatic Cancer Cell. Aug, 2016 | Pubmed ID: 27477511 Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions Cell Reports. Mar, 2016 | Pubmed ID: 26947075 Ablation of Sensory Neurons in a Genetic Model of Pancreatic Ductal Adenocarcinoma Slows Initiation and Progression of Cancer Proceedings of the National Academy of Sciences of the United States of America. Mar, 2016 | Pubmed ID: 26929329 Ductal Pancreatic Cancer Modeling and Drug Screening Using Human Pluripotent Stem Cell- and Patient-derived Tumor Organoids Nature Medicine. Nov, 2015 | Pubmed ID: 26501191 Oligodendrocyte Regeneration and CNS Remyelination Require TACE/ADAM17 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2015 | Pubmed ID: 26338334 Somatostatin Receptor Subtype 2 As Pancreatic Tumorigenesis Suppressor: Identification of a New Targetable Signaling Node Gastroenterology. Jun, 2015 | Pubmed ID: 25921374 ADAM10 Regulates Notch Function in Intestinal Stem Cells of Mice Gastroenterology. Oct, 2014 | Pubmed ID: 25038433 Identification and Manipulation of Biliary Metaplasia in Pancreatic Tumors Gastroenterology. Jan, 2014 | Pubmed ID: 23999170 独特 TCR 信号传导通路驱动器中 T 细胞增殖和细胞因子产生。 Nature Immunology. Feb, 2013 | Pubmed ID: 23377202 Constitutive α- and β-secretase Cleavages of the Amyloid Precursor Protein Are Partially Coupled in Neurons, but Not in Frequently Used Cell Lines Neurobiology of Disease. Jan, 2013 | Pubmed ID: 22940630 ADAM10 is Essential for Notch2-dependent Marginal Zone B Cell Development and CD23 Cleavage in Vivo The Journal of Experimental Medicine. Mar, 2010 | Pubmed ID: 20156974 手动复用荧光免疫学的优化、设计和避免陷阱 Jenny Lazarus1, Yagiz Akiska1, Mirna Perusina Lanfranca1, Lawrence Delrosario1, Lei Sun1, Daniel Long2, Jiaqi Shi3, Howard Crawford2, Marina P. Di Magliano1, Weiping Zou1, Timothy Frankel1 1Department of Surgery, University of Michigan, 2Department of Molecular and Cellular Physiology, University of Michigan, 3Department of Pathology, University of Michigan JoVE 59915 Recherche en cancérologie
手动复用荧光免疫学的优化、设计和避免陷阱 Jenny Lazarus1, Yagiz Akiska1, Mirna Perusina Lanfranca1, Lawrence Delrosario1, Lei Sun1, Daniel Long2, Jiaqi Shi3, Howard Crawford2, Marina P. Di Magliano1, Weiping Zou1, Timothy Frankel1 1Department of Surgery, University of Michigan, 2Department of Molecular and Cellular Physiology, University of Michigan, 3Department of Pathology, University of Michigan JoVE 59915 Recherche en cancérologie