Hui-Yao Lan Li Ka Shing Institute of Health Sciences and Department of Medicine & Therapeutics The Chinese University of Hong Kong Biography Publications Institution JoVE Articles Hui-Yao Lan has not added a biography. If you are Hui-Yao Lan and would like to personalize this page please email our Author Liaison for assistance. Publications The Proto-oncogene Tyrosine Protein Kinase Src is Essential for Macrophage-myofibroblast Transition During Renal Scarring Kidney International. Jan, 2018 | Pubmed ID: 29042082 Lethal (3) Malignant Brain Tumor Like 2 (L3MBTL2) Protein Protects Against Kidney Injury by Inhibiting the DNA Damage-p53-apoptosis Pathway in Renal Tubular Cells Kidney International. Dec, 2017 | Pubmed ID: 29276099 Novel LncRNA Erbb4-IR Promotes Diabetic Kidney Injury in Db/db Mice by Targeting MiR-29b Diabetes. Dec, 2017 | Pubmed ID: 29222368 TGF-β Mediates Renal Fibrosis Via the Smad3-Erbb4-IR Long Noncoding RNA Axis Molecular Therapy : the Journal of the American Society of Gene Therapy. Oct, 2017 | Pubmed ID: 29102563 Deletion of Angiotensin-Converting Enzyme-2 Promotes Hypertensive Nephropathy by Targeting Smad7 for Ubiquitin Degradation Hypertension (Dallas, Tex. : 1979). Oct, 2017 | Pubmed ID: 28808068 Defective CFTR Leads to Aberrant β-catenin Activation and Kidney Fibrosis Scientific Reports. Jul, 2017 | Pubmed ID: 28701694 The Incidence, Risk Factors and In-hospital Mortality of Acute Kidney Injury in Patients After Abdominal Aortic Aneurysm Repair Surgery BMC Nephrology. May, 2017 | Pubmed ID: 28569144 Smad7 Protects Against Acute Kidney Injury by Rescuing Tubular Epithelial Cells from the G1 Cell Cycle Arrest Clinical Science (London, England : 1979). Aug, 2017 | Pubmed ID: 28566468 The Regulatory T-cell Transcription Factor Foxp3 Protects Against Crescentic Glomerulonephritis Scientific Reports. May, 2017 | Pubmed ID: 28469165 C-reactive Protein and Ageing Clinical and Experimental Pharmacology & Physiology. Dec, 2017 | Pubmed ID: 28378496 Smad3 Promotes Cancer Progression by Inhibiting E4BP4-mediated NK Cell Development Nature Communications. Mar, 2017 | Pubmed ID: 28262747 Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury Journal of the American Society of Nephrology : JASN. Jul, 2017 | Pubmed ID: 28209809 N-acetyl-seryl-aspartyl-lysyl-proline Mediates the Anti-fibrotic Properties of Captopril in Unilateral Ureteric Obstructed BALB/C Mice Nephrology (Carlton, Vic.). Jan, 2017 | Pubmed ID: 28075040 The Pattern Recognition Receptor, Mincle, is Essential for Maintaining the M1 Macrophage Phenotype in Acute Renal Inflammation Kidney International. Mar, 2017 | Pubmed ID: 28017324 Peritoneal Inflammation and Fibrosis in C-reactive Protein Transgenic Mice Undergoing Peritoneal Dialysis Solution Treatment Nephrology (Carlton, Vic.). Feb, 2017 | Pubmed ID: 26857687 Inflammatory Macrophages Can Transdifferentiate into Myofibroblasts During Renal Fibrosis Cell Death & Disease. Dec, 2016 | Pubmed ID: 27906172 Calcineurin Inhibitors Cyclosporin A and Tacrolimus Protect Against Podocyte Injury Induced by Puromycin Aminonucleoside in Rodent Models Scientific Reports. Sep, 2016 | Pubmed ID: 27580845 C-reactive Protein Promotes Acute Kidney Injury Via Smad3-dependent Inhibition of CDK2/cyclin E Kidney International. Sep, 2016 | Pubmed ID: 27470679 Validity of Leptin Receptor-deficiency (db/db) Type 2 Diabetes Mellitus Mice As a Model of Secondary Osteoporosis Scientific Reports. Jun, 2016 | Pubmed ID: 27283954 TGF-β: the Master Regulator of Fibrosis Nature Reviews. Nephrology. 06, 2016 | Pubmed ID: 27108839 Therapeutic Effects of Tangshen Formula on Diabetic Nephropathy in Rats PloS One. 2016 | Pubmed ID: 26807792 TGF-β/Smad3 Signalling Regulates the Transition of Bone Marrow-derived Macrophages into Myofibroblasts During Tissue Fibrosis Oncotarget. Feb, 2016 | Pubmed ID: 26684242 Macrophage Phenotype in Kidney Injury and Repair Kidney Diseases (Basel, Switzerland). Sep, 2015 | Pubmed ID: 27536674 N-Acetyl-seryl-aspartyl-lysyl-proline Alleviates Renal Fibrosis Induced by Unilateral Ureteric Obstruction in BALB/C Mice Mediators of Inflammation. 2015 | Pubmed ID: 26508815 Treatment of Renal Fibrosis by Rebalancing TGF-β/Smad Signaling with the Combination of Asiatic Acid and Naringenin Oncotarget. Nov, 2015 | Pubmed ID: 26474462 Deletion of Smad3 Improves Cardiac Allograft Rejection in Mice Oncotarget. Jul, 2015 | Pubmed ID: 26219259 Smad7 Protects Against Chronic Aristolochic Acid Nephropathy in Mice Oncotarget. May, 2015 | Pubmed ID: 25883225 Renoprotective Effect of Berberine on Type 2 Diabetic Nephropathy in Rats Clinical and Experimental Pharmacology & Physiology. Jun, 2015 | Pubmed ID: 25867602 Transient Receptor Potential Channel M2 Contributes to Neointimal Hyperplasia in Vascular Walls Biochimica Et Biophysica Acta. Jul, 2015 | Pubmed ID: 25857618 TGF-β/Smad Signaling in Renal Fibrosis Frontiers in Physiology. 2015 | Pubmed ID: 25852569 Long Noncoding RNA Arid2-IR Is a Novel Therapeutic Target for Renal Inflammation Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2015 | Pubmed ID: 25743111 Metabolomic and Lipidomic Study of the Protective Effect of Chaihuang-Yishen Formula on Rats with Diabetic Nephropathy Journal of Ethnopharmacology. May, 2015 | Pubmed ID: 25698246 MicroRNA-29b Prevents Liver Fibrosis by Attenuating Hepatic Stellate Cell Activation and Inducing Apoptosis Through Targeting PI3K/AKT Pathway Oncotarget. Mar, 2015 | Pubmed ID: 25356754 Macrophages Promote Renal Fibrosis Through Direct and Indirect Mechanisms Kidney International Supplements. Nov, 2014 | Pubmed ID: 26312148 MicroRNA-29b Inhibits Peritoneal Fibrosis in a Mouse Model of Peritoneal Dialysis Laboratory Investigation; a Journal of Technical Methods and Pathology. Sep, 2014 | Pubmed ID: 25046436 Partial Loss of Smad7 Function Impairs Bone Remodeling, Osteogenesis and Enhances Osteoclastogenesis in Mice Bone. Oct, 2014 | Pubmed ID: 24998669 Inflammatory Processes in Renal Fibrosis Nature Reviews. Nephrology. Sep, 2014 | Pubmed ID: 24981817 Opposing Roles for Smad2 and Smad3 in Peritoneal Fibrosis in Vivo and in Vitro The American Journal of Pathology. Aug, 2014 | Pubmed ID: 24925688 Latent Transforming Growth Factor-β1 Protects Against Bleomycin-induced Lung Injury in Mice American Journal of Respiratory Cell and Molecular Biology. Dec, 2014 | Pubmed ID: 24885478 Application of MicroRNAs in Diabetes Mellitus The Journal of Endocrinology. Jul, 2014 | Pubmed ID: 24781254 Chaihuang-Yishen Granule Inhibits Diabetic Kidney Disease in Rats Through Blocking TGF-β/Smad3 Signaling PloS One. 2014 | Pubmed ID: 24646636 Tissue Kallikrein Mediates Pro-inflammatory Pathways and Activation of Protease-activated Receptor-4 in Proximal Tubular Epithelial Cells PloS One. 2014 | Pubmed ID: 24586431 MiR-29b As a Therapeutic Agent for Angiotensin II-induced Cardiac Fibrosis by Targeting TGF-β/Smad3 Signaling Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2014 | Pubmed ID: 24569834 Identification of Novel Long Noncoding RNAs Associated with TGF-β/Smad3-mediated Renal Inflammation and Fibrosis by RNA Sequencing The American Journal of Pathology. Feb, 2014 | Pubmed ID: 24262754 Dragon (repulsive Guidance Molecule RGMb) Inhibits E-cadherin Expression and Induces Apoptosis in Renal Tubular Epithelial Cells The Journal of Biological Chemistry. Nov, 2013 | Pubmed ID: 24052264 Deficiency of Smad7 Enhances Cardiac Remodeling Induced by Angiotensin II Infusion in a Mouse Model of Hypertension PloS One. 2013 | Pubmed ID: 23894614 Smad7 Inhibits Angiotensin II-induced Hypertensive Cardiac Remodelling Cardiovascular Research. Sep, 2013 | Pubmed ID: 23761400 Smads As Therapeutic Targets for Chronic Kidney Disease Kidney Research and Clinical Practice. Mar, 2012 | Pubmed ID: 26889404 TGF-β/Smad Signaling in Kidney Disease Seminars in Nephrology. May, 2012 | Pubmed ID: 22835454 Asiatic Acid Inhibits Liver Fibrosis by Blocking TGF-beta/Smad Signaling in Vivo and in Vitro PloS One. 2012 | Pubmed ID: 22363627 Transforming Growth Factor-β/Smad Signalling in Diabetic Nephropathy Clinical and Experimental Pharmacology & Physiology. Aug, 2012 | Pubmed ID: 22211842 Diverse Roles of TGF-β Receptor II in Renal Fibrosis and Inflammation in Vivo and in Vitro The Journal of Pathology. Jun, 2012 | Pubmed ID: 22190171 Disruption of Smad4 Impairs TGF-β/Smad3 and Smad7 Transcriptional Regulation During Renal Inflammation and Fibrosis in Vivo and in Vitro Kidney International. Feb, 2012 | Pubmed ID: 22048127 Diverse Roles of TGF-β/Smads in Renal Fibrosis and Inflammation International Journal of Biological Sciences. 2011 | Pubmed ID: 21927575 Diabetes Complications: the MicroRNA Perspective Diabetes. Jul, 2011 | Pubmed ID: 21709278 Transforming Growth Factor-β and Smads Contributions to Nephrology. 2011 | Pubmed ID: 21659760 The Protective Role of Smad7 in Diabetic Kidney Disease: Mechanism and Therapeutic Potential Diabetes. Feb, 2011 | Pubmed ID: 20980457 Angiotensin II Induces Connective Tissue Growth Factor and Collagen I Expression Via Transforming Growth Factor-beta-dependent and -independent Smad Pathways: the Role of Smad3 Hypertension (Dallas, Tex. : 1979). Oct, 2009 | Pubmed ID: 19667256 एक उपंयास फीडर इन विट्रो में Murine प्राकृतिक हत्यारा कोशिकाओं के बड़े पैमाने पर उत्पादन के लिए मुफ्त प्रणाली Patrick Ming-Kuen Tang1,2, Philip Chiu-Tsun Tang2, Jeff Yat-Fai Chung2, Jessica Shuk Chun Hung2, Qing-Ming Wang2, Guang-Yu Lian2, Jingyi Sheng2, Xiao-Ru Huang2, Ka-Fai To1, Hui-Yao Lan2 1Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, 2Li Ka Shing Institute of Health Sciences and Department of Medicine & Therapeutics, The Chinese University of Hong Kong JoVE 56785 Immunologie et Infection
एक उपंयास फीडर इन विट्रो में Murine प्राकृतिक हत्यारा कोशिकाओं के बड़े पैमाने पर उत्पादन के लिए मुफ्त प्रणाली Patrick Ming-Kuen Tang1,2, Philip Chiu-Tsun Tang2, Jeff Yat-Fai Chung2, Jessica Shuk Chun Hung2, Qing-Ming Wang2, Guang-Yu Lian2, Jingyi Sheng2, Xiao-Ru Huang2, Ka-Fai To1, Hui-Yao Lan2 1Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, 2Li Ka Shing Institute of Health Sciences and Department of Medicine & Therapeutics, The Chinese University of Hong Kong JoVE 56785 Immunologie et Infection