Ian A. Blair Center for Cancer Pharmacology University of Pennsylvania Biography Publications Institution JoVE Articles Ian A. Blair has not added a biography. If you are Ian A. Blair and would like to personalize this page please email our Author Liaison for assistance. Publications Relative Quantification of Serum Proteins from Pancreatic Ductal Adenocarcinoma Patients by Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Journal of Proteome Research. Feb, 2012 | Pubmed ID: 22264027 SILEC: a Protocol for Generating and Using Isotopically Labeled Coenzyme A Mass Spectrometry Standards Nature Protocols. Jan, 2012 | Pubmed ID: 22157971 Multidrug Resistance Protein (MRP) 4 Attenuates Benzo[a]pyrene-mediated DNA-adduct Formation in Human Bronchoalveolar H358 Cells Toxicology Letters. Feb, 2012 | Pubmed ID: 22155354 Quantitation of Benzo[a]pyrene Metabolic Profiles in Human Bronchoalveolar (H358) Cells by Stable Isotope Dilution Liquid Chromatography-atmospheric Pressure Chemical Ionization Mass Spectrometry Chemical Research in Toxicology. Nov, 2011 | Pubmed ID: 21962213 Rotenone-mediated Changes in Intracellular Coenzyme A Thioester Levels: Implications for Mitochondrial Dysfunction Chemical Research in Toxicology. Oct, 2011 | Pubmed ID: 21950265 11-Oxoeicosatetraenoic Acid is a Cyclooxygenase-2/15-hydroxyprostaglandin Dehydrogenase-derived Antiproliferative Eicosanoid Chemical Research in Toxicology. Dec, 2011 | Pubmed ID: 21916491 Oncogene-induced Nrf2 Transcription Promotes ROS Detoxification and Tumorigenesis Nature. Jul, 2011 | Pubmed ID: 21734707 Detoxication of Structurally Diverse Polycyclic Aromatic Hydrocarbon (PAH) O-quinones by Human Recombinant Catechol-O-methyltransferase (COMT) Via O-methylation of PAH Catechols The Journal of Biological Chemistry. Jul, 2011 | Pubmed ID: 21622560 Stereospecific Reduction of 5β-reduced Steroids by Human Ketosteroid Reductases of the AKR (aldo-keto Reductase) Superfamily: Role of AKR1C1-AKR1C4 in the Metabolism of Testosterone and Progesterone Via the 5β-reductase Pathway The Biochemical Journal. Jul, 2011 | Pubmed ID: 21521174 Analysis of the Human Pancreatic Stellate Cell Secreted Proteome Pancreas. May, 2011 | Pubmed ID: 21499210 Liquid Chromatography/mass Spectrometry of Pre-ionized Girard P Derivatives for Quantifying Estrone and Its Metabolites in Serum from Postmenopausal Women Rapid Communications in Mass Spectrometry : RCM. May, 2011 | Pubmed ID: 21488127 Nicotine Exposure and Metabolizer Phenotypes from Analysis of Urinary Nicotine and Its 15 Metabolites by LC-MS Bioanalysis. Apr, 2011 | Pubmed ID: 21452992 CYP3A4 Mediates Growth of Estrogen Receptor-positive Breast Cancer Cells in Part by Inducing Nuclear Translocation of Phospho-Stat3 Through Biosynthesis of (±)-14,15-epoxyeicosatrienoic Acid (EET) The Journal of Biological Chemistry. May, 2011 | Pubmed ID: 21402692 Stable Isotope Labeling by Essential Nutrients in Cell Culture for Preparation of Labeled Coenzyme A and Its Thioesters Analytical Chemistry. Feb, 2011 | Pubmed ID: 21268609 Prediction of Postoperative Recurrence-free Survival in Non-small Cell Lung Cancer by Using an Internationally Validated Gene Expression Model Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2011 | Pubmed ID: 21242119 A New Liquid Chromatography/mass Spectrometry Method for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in Urine Rapid Communications in Mass Spectrometry : RCM. Jan, 2011 | Pubmed ID: 21154658 Thermal Stability of Bimatoprost, Latanoprost, and Travoprost Under Simulated Daily Use Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics. Feb, 2011 | Pubmed ID: 21117945 Regulation of Benzo[a]pyrene-mediated DNA- and Glutathione-adduct Formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in Human Lung Cells Chemical Research in Toxicology. Jan, 2011 | Pubmed ID: 21028851 Deciphering the Human Platelet Sheddome Blood. Jan, 2011 | Pubmed ID: 20962327 Analysis of Epoxyeicosatrienoic Acids by Chiral Liquid Chromatography/electron Capture Atmospheric Pressure Chemical Ionization Mass Spectrometry Using [13C]-analog Internal Standards Rapid Communications in Mass Spectrometry : RCM. Nov, 2010 | Pubmed ID: 20972997 Interferon Regulatory Factor-8-driven Myeloid Differentiation is Regulated by 12/15-lipoxygenase-mediated Redox Signaling Experimental Hematology. Nov, 2010 | Pubmed ID: 20647030 Genetic and Lifestyle Variables Associated with Homocysteine Concentrations and the Distribution of Folate Derivatives in Healthy Premenopausal Women Birth Defects Research. Part A, Clinical and Molecular Teratology. Aug, 2010 | Pubmed ID: 20544798 20-HETE Mediates Ozone-induced, Neutrophil-independent Airway Hyper-responsiveness in Mice PloS One. 2010 | Pubmed ID: 20422032 Hematopoietic Stem Cell Function Requires 12/15-lipoxygenase-dependent Fatty Acid Metabolism Blood. Jun, 2010 | Pubmed ID: 20357242 Stable-isotope Dilution LC–MS for Quantitative Biomarker Analysis Bioanalysis. Feb, 2010 | Pubmed ID: 20352077 A 13-Oxo-9,10-epoxytridecenoate Phospholipid Analogue of the Genotoxic 4,5-epoxy-2E-decenal: Detection in Vivo, Chemical Synthesis, and Adduction with DNA Chemical Research in Toxicology. Mar, 2010 | Pubmed ID: 20131875 Analysis of Estrogens in Serum and Plasma from Postmenopausal Women: Past Present, and Future Steroids. Apr, 2010 | Pubmed ID: 20109478 Liquid Chromatography-mass Spectrometry (LC-MS) of Steroid Hormone Metabolites and Its Applications The Journal of Steroid Biochemistry and Molecular Biology. Aug, 2010 | Pubmed ID: 20083198 Aldo-keto Reductase 1C3 Expression in MCF-7 Cells Reveals Roles in Steroid Hormone and Prostaglandin Metabolism That May Explain Its Over-expression in Breast Cancer The Journal of Steroid Biochemistry and Molecular Biology. Feb, 2010 | Pubmed ID: 20036328 Analysis of Endogenous Glutathione-adducts and Their Metabolites Biomedical Chromatography : BMC. Jan, 2010 | Pubmed ID: 20017120 Secondhand Smoke Inhibits Both Cl- and K+ Conductances in Normal Human Bronchial Epithelial Cells Respiratory Research. 2009 | Pubmed ID: 19943936 12/15-lipoxygenase-dependent Myeloid Production of Interleukin-12 is Essential for Resistance to Chronic Toxoplasmosis Infection and Immunity. Dec, 2009 | Pubmed ID: 19822654 Differential Secreted Proteome Approach in Murine Model for Candidate Biomarker Discovery in Colon Cancer Journal of Proteome Research. Nov, 2009 | Pubmed ID: 19769411 Aryl Hydrocarbon Receptor Facilitates DNA Strand Breaks and 8-oxo-2'-deoxyguanosine Formation by the Aldo-keto Reductase Product Benzo[a]pyrene-7,8-dione The Journal of Biological Chemistry. Oct, 2009 | Pubmed ID: 19726680 Targeted Chiral Lipidomics Analysis of Bioactive Eicosanoid Lipids in Cellular Systems BMB Reports. Jul, 2009 | Pubmed ID: 19643036 A 4-oxo-2(E)-nonenal-derived Glutathione Adduct from 15-lipoxygenase-1-mediated Oxidation of Cytosolic and Esterified Arachidonic Acid Free Radical Biology & Medicine. Oct, 2009 | Pubmed ID: 19576981 15-oxo-Eicosatetraenoic Acid, a Metabolite of Macrophage 15-hydroxyprostaglandin Dehydrogenase That Inhibits Endothelial Cell Proliferation Molecular Pharmacology. Sep, 2009 | Pubmed ID: 19535459 15(S)-Lipoxygenase-1 Associates with Neutral Lipid Droplets in Macrophage Foam Cells: Evidence of Lipid Droplet Metabolism Journal of Lipid Research. Dec, 2009 | Pubmed ID: 19528634 Folate and Homocysteine Phenotypes: Comparative Findings Using Research and Clinical Laboratory Data Clinical Biochemistry. Aug, 2009 | Pubmed ID: 19427846 5-Lipoxygenase-mediated Endogenous DNA Damage The Journal of Biological Chemistry. Jun, 2009 | Pubmed ID: 19390118 The Post-synaptic Density of Human Postmortem Brain Tissues: an Experimental Study Paradigm for Neuropsychiatric Illnesses PloS One. 2009 | Pubmed ID: 19370153 Absolute Quantification of Phosphorylation on the Kinase Activation Loop of Cellular Focal Adhesion Kinase by Stable Isotope Dilution Liquid Chromatography/mass Spectrometry Analytical Chemistry. May, 2009 | Pubmed ID: 19354260 Overexpression of Human 15(S)-lipoxygenase-1 in RAW Macrophages Leads to Increased Cholesterol Mobilization and Reverse Cholesterol Transport Arteriosclerosis, Thrombosis, and Vascular Biology. Jun, 2009 | Pubmed ID: 19325142 Analysis of 7,8-dihydro-8-oxo-2'-deoxyguanosine in Cellular DNA During Oxidative Stress Chemical Research in Toxicology. May, 2009 | Pubmed ID: 19309085 Identification and Quantification of Preterm Birth Biomarkers in Human Cervicovaginal Fluid by Liquid Chromatography/tandem Mass Spectrometry Journal of Proteome Research. May, 2009 | Pubmed ID: 19271751 Human Cytosolic Hydroxysteroid Dehydrogenases of the Aldo-ketoreductase Superfamily Catalyze Reduction of Conjugated Steroids: Implications for Phase I and Phase II Steroid Hormone Metabolism The Journal of Biological Chemistry. Apr, 2009 | Pubmed ID: 19218247 TNFalpha-dependent Hepatic Steatosis and Liver Degeneration Caused by Mutation of Zebrafish S-adenosylhomocysteine Hydrolase Development (Cambridge, England). Mar, 2009 | Pubmed ID: 19201949 Stable Isotope Dilution Multidimensional Liquid Chromatography-tandem Mass Spectrometry for Pancreatic Cancer Serum Biomarker Discovery Journal of Proteome Research. Mar, 2009 | Pubmed ID: 19199705 The Up-regulation of Monocyte Chemoattractant Protein-1 (MCP-1) in Ea.hy 926 Endothelial Cells Under Long-term Low Folate Stress is Mediated by the P38 MAPK Pathway Atherosclerosis. Jul, 2009 | Pubmed ID: 19152916 Synthesis of Phenol and Quinone Metabolites of Benzo[a]pyrene, a Carcinogenic Component of Tobacco Smoke Implicated in Lung Cancer The Journal of Organic Chemistry. Jan, 2009 | Pubmed ID: 19132942 Quantification of Focal Adhesion Kinase Activation Loop Phosphorylation As a Biomarker of Src Activity Molecular Pharmacology. Mar, 2009 | Pubmed ID: 19098120 Two Distinct Translesion Synthesis Pathways Across a Lipid Peroxidation-derived DNA Adduct in Mammalian Cells The Journal of Biological Chemistry. Jan, 2009 | Pubmed ID: 18981176 Genetic and Biochemical Determinants of Serum Concentrations of Monocyte Chemoattractant Protein-1, a Potential Neural Tube Defect Risk Factor Birth Defects Research. Part A, Clinical and Molecular Teratology. Oct, 2008 | Pubmed ID: 18937353 Quantification of Key Red Blood Cell Folates from Subjects with Defined MTHFR 677C>T Genotypes Using Stable Isotope Dilution Liquid Chromatography/mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. Aug, 2008 | Pubmed ID: 18634122 The Pattern of P53 Mutations Caused by PAH O-quinones is Driven by 8-oxo-dGuo Formation While the Spectrum of Mutations is Determined by Biological Selection for Dominance Chemical Research in Toxicology. May, 2008 | Pubmed ID: 18489080 Evidence for the Aldo-keto Reductase Pathway of Polycyclic Aromatic Trans-dihydrodiol Activation in Human Lung A549 Cells Proceedings of the National Academy of Sciences of the United States of America. May, 2008 | Pubmed ID: 18474869 DNA Adducts with Lipid Peroxidation Products The Journal of Biological Chemistry. Jun, 2008 | Pubmed ID: 18285329 Synthesis of Dibenzo[def,p]chrysene, Its Active Metabolites, and Their 13C-labeled Analogues Organic Letters. Mar, 2008 | Pubmed ID: 18284245 Fjord-region Benzo[g]chrysene-11,12-dihydrodiol and Benzo[c]phenanthrene-3,4-dihydrodiol As Substrates for Rat Liver Dihydrodiol Dehydrogenase (AKR1C9): Structural Basis for Stereochemical Preference Chemical Research in Toxicology. Mar, 2008 | Pubmed ID: 18251511 Determination of Cellular Redox Status by Stable Isotope Dilution Liquid Chromatography/mass Spectrometry Analysis of Glutathione and Glutathione Disulfide Rapid Communications in Mass Spectrometry : RCM. 2008 | Pubmed ID: 18215009 Analysis of the Zebrafish Proteome During Embryonic Development Molecular & Cellular Proteomics : MCP. May, 2008 | Pubmed ID: 18212345 Strategies for Synthesis of Adducts of Omicron-quinone Metabolites of Carcinogenic Polycyclic Aromatic Hydrocarbons with 2'-deoxyribonucleosides The Journal of Organic Chemistry. Feb, 2008 | Pubmed ID: 18181642 Targeted Chiral Lipidomics Analysis by Liquid Chromatography Electron Capture Atmospheric Pressure Chemical Ionization Mass Spectrometry (LC-ECAPCI/MS) Methods in Enzymology. 2007 | Pubmed ID: 17954234 Cyclooxygenase-2-mediated Metabolism of Arachidonic Acid to 15-oxo-eicosatetraenoic Acid by Rat Intestinal Epithelial Cells Chemical Research in Toxicology. Nov, 2007 | Pubmed ID: 17910482 Metabolism of Benzo[a]pyrene in Human Bronchoalveolar H358 Cells Using Liquid Chromatography-mass Spectrometry Chemical Research in Toxicology. Sep, 2007 | Pubmed ID: 17702526 A Novel 4-oxo-2(E)-nonenal-derived Endogenous Thiadiazabicyclo Glutathione Adduct Formed During Cellular Oxidative Stress Chemical Research in Toxicology. Jul, 2007 | Pubmed ID: 17550273 Aldo-keto Reductase- and Cytochrome P450-dependent Formation of Benzo[a]pyrene-derived DNA Adducts in Human Bronchoalveolar Cells Chemical Research in Toxicology. Mar, 2007 | Pubmed ID: 17295519 EBP, a Program for Protein Identification Using Multiple Tandem Mass Spectrometry Datasets Molecular & Cellular Proteomics : MCP. Mar, 2007 | Pubmed ID: 17164401 Quantification of Intracellular Homocysteine by Stable Isotope Dilution Liquid Chromatography/tandem Mass Spectrometry Biomedical Chromatography : BMC. Jan, 2007 | Pubmed ID: 17121413 LC/ESI/MS Analysis of Saturated and Unsaturated Fatty Acids in Rat Intestinal Epithelial Cells Current Drug Metabolism. Dec, 2006 | Pubmed ID: 17168692 Characterization of an Etoposide-glutathione Conjugate Derived from Metabolic Activation by Human Cytochrome P450 Current Drug Metabolism. Dec, 2006 | Pubmed ID: 17168690 Endogenous Glutathione Adducts Current Drug Metabolism. Dec, 2006 | Pubmed ID: 17168687 Convenient and Efficient Syntheses of 4-hydroxy-2(E)-nonenal and 4-oxo-2(E)-nonenal Lipids. Sep, 2006 | Pubmed ID: 17152925 Quantitative Analysis of Amyloid Beta Peptides in Cerebrospinal Fluid of Alzheimer's Disease Patients by Immunoaffinity Purification and Stable Isotope Dilution Liquid Chromatography/negative Electrospray Ionization Tandem Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. 2006 | Pubmed ID: 17117458 Analysis of Phosphorylation Sites on Focal Adhesion Kinase Using Nanospray Liquid Chromatography/multiple Reaction Monitoring Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. 2006 | Pubmed ID: 17117420 Journal of Proteome Research. Oct, 2006 | Pubmed ID: 17022645 Translesion DNA Synthesis Across the Heptanone--etheno-2'-deoxycytidine Adduct in Cells Chemical Research in Toxicology. Aug, 2006 | Pubmed ID: 16918247 Characterization of a Lipid Hydroperoxide-derived RNA Adduct in Rat Intestinal Epithelial Cells Chemical Research in Toxicology. Jun, 2006 | Pubmed ID: 16780360 Quantification of Benzo[a]pyrene Diol Epoxide DNA-adducts by Stable Isotope Dilution Liquid Chromatography/tandem Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. 2006 | Pubmed ID: 16557497 Liquid Chromatography/tandem Mass Spectrometry Characterization of Oxidized Amyloid Beta Peptides As Potential Biomarkers of Alzheimer's Disease Rapid Communications in Mass Spectrometry : RCM. 2006 | Pubmed ID: 16470704 Mild Folate Deficiency Induces a Proatherosclerotic Phenotype in Endothelial Cells Atherosclerosis. Nov, 2006 | Pubmed ID: 16469322 Endogenous Lipid Hydroperoxide-mediated DNA-adduct Formation in Min Mice The Journal of Biological Chemistry. Apr, 2006 | Pubmed ID: 16449227 Competing Roles of Aldo-keto Reductase 1A1 and Cytochrome P4501B1 in Benzo[a]pyrene-7,8-diol Activation in Human Bronchoalveolar H358 Cells: Role of AKRs in P4501B1 Induction Chemical Research in Toxicology. Jan, 2006 | Pubmed ID: 16411658 Interaction with Phospholipids Modulates Alpha-synuclein Nitration and Lipid-protein Adduct Formation The Biochemical Journal. Jan, 2006 | Pubmed ID: 16146428 Analysis of Protein Expression During Oxidative Stress in Breast Epithelial Cells Using a Stable Isotope Labeled Proteome Internal Standard Journal of Proteome Research. Nov-Dec, 2005 | Pubmed ID: 16335945 Induction of Endothelial Cell Apoptosis by Lipid Hydroperoxide-derived Bifunctional Electrophiles Free Radical Biology & Medicine. Nov, 2005 | Pubmed ID: 16214032 Characterization of Proteins in Human Pancreatic Cancer Serum Using Differential Gel Electrophoresis and Tandem Mass Spectrometry Journal of Proteome Research. Sep-Oct, 2005 | Pubmed ID: 16212428 Effect of Immunoaffinity Depletion of Human Serum During Proteomic Investigations Journal of Proteome Research. Sep-Oct, 2005 | Pubmed ID: 16212426 Targeted Chiral Lipidomics Analysis Prostaglandins & Other Lipid Mediators. Sep, 2005 | Pubmed ID: 16099399 Cyclooxygenase-2-mediated DNA Damage The Journal of Biological Chemistry. Aug, 2005 | Pubmed ID: 15964853 4-Hydroperoxy-2-nonenal-induced Formation of 1,N2-etheno-2'-deoxyguanosine Adducts Chemical Research in Toxicology. Apr, 2005 | Pubmed ID: 15833039 DNA Topoisomerase II in Therapy-related Acute Promyelocytic Leukemia The New England Journal of Medicine. Apr, 2005 | Pubmed ID: 15829534 Novel Lipid Hydroperoxide-derived Hemoglobin Histidine Adducts As Biomarkers of Oxidative Stress Journal of Mass Spectrometry : JMS. Jun, 2005 | Pubmed ID: 15827957 Unexpected Formation of Etheno-2'-deoxyguanosine Adducts from 5(S)-hydroperoxyeicosatetraenoic Acid: Evidence for a Bis-hydroperoxide Intermediate Chemical Research in Toxicology. Mar, 2005 | Pubmed ID: 15777099 Dioxododecenoic Acid: a Lipid Hydroperoxide-derived Bifunctional Electrophile Responsible for Etheno DNA Adduct Formation Chemical Research in Toxicology. Mar, 2005 | Pubmed ID: 15777096 Analysis of FeII-mediated Decomposition of a Linoleic Acid-derived Lipid Hydroperoxide by Liquid Chromatography/mass Spectrometry Journal of Mass Spectrometry : JMS. May, 2005 | Pubmed ID: 15739161 Liquid Chromatography/mass Spectrometry Analysis of Bifunctional Electrophiles and DNA Adducts from Vitamin C Mediated Decomposition of 15-hydroperoxyeicosatetraenoic Acid Rapid Communications in Mass Spectrometry : RCM. 2005 | Pubmed ID: 15723435 Viniferin Formation by COX-1: Evidence for Radical Intermediates During Co-oxidation of Resveratrol Journal of Natural Products. Jan, 2005 | Pubmed ID: 15679314 Kinetics and Regulation of Cytochrome P450-mediated Etoposide Metabolism Drug Metabolism and Disposition: the Biological Fate of Chemicals. Sep, 2004 | Pubmed ID: 15319341 Plasma Etoposide Catechol Increases in Pediatric Patients Undergoing Multiple-day Chemotherapy with Etoposide Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. May, 2004 | Pubmed ID: 15131033 A Novel Lipid Hydroperoxide-derived Modification to Arginine Chemical Research in Toxicology. Dec, 2003 | Pubmed ID: 14680374 Reciprocal DNA Topoisomerase II Cleavage Events at 5'-TATTA-3' Sequences in MLL and AF-9 Create Homologous Single-stranded Overhangs That Anneal to Form Der(11) and Der(9) Genomic Breakpoint Junctions in Treatment-related AML Without Further Processing Oncogene. Nov, 2003 | Pubmed ID: 14627986 Targeted Lipidomics Using Electron Capture Atmospheric Pressure Chemical Ionization Mass Spectrometry Rapid Communications in Mass Spectrometry : RCM. 2003 | Pubmed ID: 14515314 A Novel Lipid Hydroperoxide-derived Cyclic Covalent Modification to Histone H4 The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12930824 Characterization of 2'-deoxycytidine Adducts Derived from 4-oxo-2-nonenal, a Novel Lipid Peroxidation Product Chemical Research in Toxicology. Jul, 2003 | Pubmed ID: 12870892 A Human Melanoma Xenograft in a Nude Rat Responds to Isolated Limb Perfusion with TNF Plus Melphalan Surgery. Apr, 2003 | Pubmed ID: 12717360 Analysis of Anticancer Drugs and Their Metabolites by Mass Spectrometry Current Drug Metabolism. Oct, 2002 | Pubmed ID: 12369893 Activation of Polycyclic Aromatic Hydrocarbon Trans-dihydrodiol Proximate Carcinogens by Human Aldo-keto Reductase (AKR1C) Enzymes and Their Functional Overexpression in Human Lung Carcinoma (A549) Cells The Journal of Biological Chemistry. Jul, 2002 | Pubmed ID: 11978787 4,5-Epoxy-2(E)-decenal-induced Formation of 1,N(6)-etheno-2'-deoxyadenosine and 1,N(2)-etheno-2'-deoxyguanosine Adducts Chemical Research in Toxicology. Mar, 2002 | Pubmed ID: 11896675 A Validated Liquid Chromatography/tandem Mass Spectrometry Assay for Cis-amminedichloro(2-methylpyridine)platinum(II) in Human Plasma Ultrafiltrate Analytical Chemistry. Feb, 2002 | Pubmed ID: 11838680 LC-MS analyse av humane blodplater som en plattform for å studere mitokondrie Metabolism Andrew J. Worth*1,2, Dylan M. Marchione*2,3, Robert C. Parry1,2, Qingqing Wang2,3, Kevin P. Gillespie2,3, Noelle N. Saillant4, Carrie Sims4, Clementina Mesaros1,2, Nathaniel W. Snyder5, Ian A. Blair1,2 1Center for Cancer Pharmacology, University of Pennsylvania, 2Center for Excellence in Environmental Toxicology, University of Pennsylvania, 3Penn SRP and Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, 4Division of Traumatology, Department of Surgery, Critical Care and Acute Care Surgery, University of Pennsylvania, 5A.J. Drexel Autism Institute, Drexel University JoVE 53941 Environnement Vilkårlige Metabolomics fra biologiske kilder Bruke UltraPerformance væskekromatografi-High Resolution massespektrometri (UPLC-HRMS) Nathaniel W. Snyder1, Maya Khezam1, Clementina A. Mesaros1, Andrew Worth1, Ian A. Blair1 1Centers for Cancer Pharmacology and Excellence in Environmental Toxicology, Department of Pharmacology, University of Pennsylvania JoVE 50433 Chimie Cellular Lipid Uttak for Målrettet Stabil isotopfortynning Liquid Chromatography-Mass Spectrometry Analysis Stacy L. Gelhaus1,2, A. Clementina Mesaros1,2, Ian A. Blair1,2 1Centers for Cancer Pharmacology and Excellence in Environmental Toxicology, University of Pennsylvania, 2Department of Pharmacology, University of Pennsylvania Bio-ingénierie
LC-MS analyse av humane blodplater som en plattform for å studere mitokondrie Metabolism Andrew J. Worth*1,2, Dylan M. Marchione*2,3, Robert C. Parry1,2, Qingqing Wang2,3, Kevin P. Gillespie2,3, Noelle N. Saillant4, Carrie Sims4, Clementina Mesaros1,2, Nathaniel W. Snyder5, Ian A. Blair1,2 1Center for Cancer Pharmacology, University of Pennsylvania, 2Center for Excellence in Environmental Toxicology, University of Pennsylvania, 3Penn SRP and Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, 4Division of Traumatology, Department of Surgery, Critical Care and Acute Care Surgery, University of Pennsylvania, 5A.J. Drexel Autism Institute, Drexel University JoVE 53941 Environnement
Vilkårlige Metabolomics fra biologiske kilder Bruke UltraPerformance væskekromatografi-High Resolution massespektrometri (UPLC-HRMS) Nathaniel W. Snyder1, Maya Khezam1, Clementina A. Mesaros1, Andrew Worth1, Ian A. Blair1 1Centers for Cancer Pharmacology and Excellence in Environmental Toxicology, Department of Pharmacology, University of Pennsylvania JoVE 50433 Chimie
Cellular Lipid Uttak for Målrettet Stabil isotopfortynning Liquid Chromatography-Mass Spectrometry Analysis Stacy L. Gelhaus1,2, A. Clementina Mesaros1,2, Ian A. Blair1,2 1Centers for Cancer Pharmacology and Excellence in Environmental Toxicology, University of Pennsylvania, 2Department of Pharmacology, University of Pennsylvania Bio-ingénierie