Jason Mercer MRC Laboratory for Molecular Cell Biology University College London Biography Publications Institution JoVE Articles Jason Mercer has not added a biography. If you are Jason Mercer and would like to personalize this page please email our Author Liaison for assistance. Publications VEGF Induces Signalling and Angiogenesis by Directing VEGFR2 Internalisation Through Macropinocytosis Journal of Cell Science. Nov, 2016 | Pubmed ID: 27656109 VirusMapper: Open-source Nanoscale Mapping of Viral Architecture Through Super-resolution Microscopy Scientific Reports. Jul, 2016 | Pubmed ID: 27374400 Infectio: a Generic Framework for Computational Simulation of Virus Transmission Between Cells MSphere. Jan-Feb, 2016 | Pubmed ID: 27303704 Cloak and Dagger: Alternative Immune Evasion and Modulation Strategies of Poxviruses Viruses. Aug, 2015 | Pubmed ID: 26308043 Viral Apoptotic Mimicry Nature Reviews. Microbiology. Aug, 2015 | Pubmed ID: 26052667 Vaccinia Virus Infection Requires Maturation of Macropinosomes Traffic (Copenhagen, Denmark). Aug, 2015 | Pubmed ID: 25869659 DNA Virus Uncoating Virology. May, 2015 | Pubmed ID: 25728300 Simultaneous Analysis of Large-scale RNAi Screens for Pathogen Entry BMC Genomics. 2014 | Pubmed ID: 25534632 Lipid Interactions During Virus Entry and Infection Cellular Microbiology. Oct, 2014 | Pubmed ID: 25131438 Next Generation Approaches to Study Virus Entry and Infection Current Opinion in Virology. Feb, 2014 | Pubmed ID: 24525289 SiRNA Screen of Early Poxvirus Genes Identifies the AAA+ ATPase D5 As the Virus Genome-uncoating Factor Cell Host & Microbe. Jan, 2014 | Pubmed ID: 24439902 Tracking Viral Genomes in Host Cells at Single-molecule Resolution Cell Host & Microbe. Oct, 2013 | Pubmed ID: 24139403 Vaccinia Virus Entry is Followed by Core Activation and Proteasome-mediated Release of the Immunomodulatory Effector VH1 from Lateral Bodies Cell Reports. Aug, 2013 | Pubmed ID: 23891003 Single-virus Fusion Experiments Reveal Proton Influx into Vaccinia Virions and Hemifusion Lag Times Biophysical Journal. Jul, 2013 | Pubmed ID: 23870263 [Cellular Protein Disposal System Assists Poxvirus Genome Uncoating] Medecine Sciences : M/S. Jun-Jul, 2013 | Pubmed ID: 23859504 Virus Interactions with Endocytic Pathways in Macrophages and Dendritic Cells Trends in Microbiology. Aug, 2013 | Pubmed ID: 23830563 Virus Entry by Endocytosis Advances in Virology. 2013 | Pubmed ID: 23710180 Biogenesis of the Vaccinia Virus Membrane: Genetic and Ultrastructural Analysis of the Contributions of the A14 and A17 Proteins Journal of Virology. Jan, 2013 | Pubmed ID: 23135725 A Facile Protocol for the Immobilisation of Vesicles, Virus Particles, Bacteria, and Yeast Cells Integrative Biology : Quantitative Biosciences from Nano to Macro. Dec, 2012 | Pubmed ID: 23147942 RNAi Screening Reveals Proteasome- and Cullin3-dependent Stages in Vaccinia Virus Infection Cell Reports. Oct, 2012 | Pubmed ID: 23084750 Direct Identification of Ligand-receptor Interactions on Living Cells and Tissues Nature Biotechnology. Oct, 2012 | Pubmed ID: 22983091 Vaccinia Virus Egress: Actin OUT with Clathrin Cell Host & Microbe. Sep, 2012 | Pubmed ID: 22980323 Gulping Rather Than Sipping: Macropinocytosis As a Way of Virus Entry Current Opinion in Microbiology. Aug, 2012 | Pubmed ID: 22749376 Cooperative Vaccinia Infection Demonstrated at the Single-cell Level Using FluidFM Nano Letters. Aug, 2012 | Pubmed ID: 22731659 Single-cell Analysis of Population Context Advances RNAi Screening at Multiple Levels Molecular Systems Biology. Apr, 2012 | Pubmed ID: 22531119 Corannulene and Its Penta-tert-butyl Derivative Co-crystallize 1:1 with Pristine C60-fullerene Chemical Communications (Cambridge, England). Jun, 2012 | Pubmed ID: 22466755 Poxvirus Host Cell Entry Current Opinion in Virology. Feb, 2012 | Pubmed ID: 22440962 Vaccinia Extracellular Virions Enter Cells by Macropinocytosis and Acid-activated Membrane Rupture The EMBO Journal. Jul, 2011 | Pubmed ID: 21792173 Viral Apoptotic Mimicry Party: P.S. Bring Your Own Gas6 Cell Host & Microbe. Apr, 2011 | Pubmed ID: 21501823 Apoptotic Mimicry: Phosphatidylserine-mediated Macropinocytosis of Vaccinia Virus Annals of the New York Academy of Sciences. Oct, 2010 | Pubmed ID: 20958316 Activation and Regulation of Store-operated Calcium Entry Journal of Cellular and Molecular Medicine. Oct, 2010 | Pubmed ID: 20807283 Vaccinia Virus Strains Use Distinct Forms of Macropinocytosis for Host-cell Entry Proceedings of the National Academy of Sciences of the United States of America. May, 2010 | Pubmed ID: 20439710 Virus Entry by Endocytosis Annual Review of Biochemistry. 2010 | Pubmed ID: 20196649 Chemico-genetic Identification of Drebrin As a Regulator of Calcium Responses The International Journal of Biochemistry & Cell Biology. Feb, 2010 | Pubmed ID: 19948240 Virus Entry by Macropinocytosis Nature Cell Biology. May, 2009 | Pubmed ID: 19404330 Vaccinia Virus Uses Macropinocytosis and Apoptotic Mimicry to Enter Host Cells Science (New York, N.Y.). Apr, 2008 | Pubmed ID: 18436786 Subversion of CtBP1-controlled Macropinocytosis by Human Adenovirus Serotype 3 The EMBO Journal. Apr, 2008 | Pubmed ID: 18323776 Emerging Perspectives in Store-operated Ca2+ Entry: Roles of Orai, Stim and TRP Biochimica Et Biophysica Acta. Nov, 2006 | Pubmed ID: 17034882 Large Store-operated Calcium Selective Currents Due to Co-expression of Orai1 or Orai2 with the Intracellular Calcium Sensor, Stim1 The Journal of Biological Chemistry. Aug, 2006 | Pubmed ID: 16807233 Genetic and Cell Biological Characterization of the Vaccinia Virus A30 and G7 Phosphoproteins Journal of Virology. Jun, 2005 | Pubmed ID: 15890954 Natural Killer T Cells: Rapid Responders Controlling Immunity and Disease The International Journal of Biochemistry & Cell Biology. Jul, 2005 | Pubmed ID: 15833265 Regulation of CXC Chemokine Receptor 4-mediated Migration by the Tec Family Tyrosine Kinase ITK The Journal of Biological Chemistry. Jul, 2004 | Pubmed ID: 15123627 Investigation of Structural and Functional Motifs Within the Vaccinia Virus A14 Phosphoprotein, an Essential Component of the Virion Membrane Journal of Virology. Aug, 2003 | Pubmed ID: 12885904 Opposing Roles of Serine/threonine Kinases MEKK1 and LOK in Regulating the CD28 Responsive Element in T-cells The Biochemical Journal. Apr, 2002 | Pubmed ID: 11903060 Open-source Single-particle Analysis for Super-resolution Microscopy with VirusMapper Robert D. M. Gray1,2, Jason Mercer1, Ricardo Henriques1,3 1MRC Laboratory for Molecular Cell Biology, University College London, 2Centre for Mathematics and Physics in Life Sciences and Experimental Biology (CoMPLEX), University College London, 3Department of Cell and Developmental Biology, University College London JoVE 55471 Biologie Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes Andreas Kühbacher1,2,3, Edith Gouin1,2,3, Jason Mercer4, Mario Emmenlauer5, Christoph Dehio5, Pascale Cossart1,2,3, Javier Pizarro-Cerdá1,2,3 1Unité des Interactions Bactéries Cellules, Pasteur Institute, 2INSERM U604, 3Institut National de la Recherche Agronomique (INRA), USC2020, 4Institute of Biochemistry, ETH Zürich, 5Focal Area Infection Biology, Biozentrum, University of Basel JoVE 51043 Immunologie et Infection
Open-source Single-particle Analysis for Super-resolution Microscopy with VirusMapper Robert D. M. Gray1,2, Jason Mercer1, Ricardo Henriques1,3 1MRC Laboratory for Molecular Cell Biology, University College London, 2Centre for Mathematics and Physics in Life Sciences and Experimental Biology (CoMPLEX), University College London, 3Department of Cell and Developmental Biology, University College London JoVE 55471 Biologie
Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes Andreas Kühbacher1,2,3, Edith Gouin1,2,3, Jason Mercer4, Mario Emmenlauer5, Christoph Dehio5, Pascale Cossart1,2,3, Javier Pizarro-Cerdá1,2,3 1Unité des Interactions Bactéries Cellules, Pasteur Institute, 2INSERM U604, 3Institut National de la Recherche Agronomique (INRA), USC2020, 4Institute of Biochemistry, ETH Zürich, 5Focal Area Infection Biology, Biozentrum, University of Basel JoVE 51043 Immunologie et Infection