Jayan Nagendran Division of Cardiac Surgery, Department of Surgery, Faculty of Medicine University of Alberta Biography Publications Institution JoVE Articles Jayan Nagendran has not added a biography. If you are Jayan Nagendran and would like to personalize this page please email our Author Liaison for assistance. Publications Bilateral Lung Transplant for Treatment of Idiopathic Pulmonary Fibrosis With Undetected Lung Adenocarcinoma: A Case Report Anticancer Research. Feb, 2022 | Pubmed ID: 35093920 Coronary Revascularization for Patients with Diabetes Mellitus: A Contemporary Systematic Review and Meta-Analysis Annals of Surgery. Jan, 2022 | Pubmed ID: 35081569 Recellularization of Xenograft Heart Valves Reduces the Xenoreactive Immune Response in an in Vivo Rat Model European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. Jan, 2022 | Pubmed ID: 34633028 ANOTHER Syndrome-Familial Presentations of Progressive Lung Disease Leading to Double Lung Transplantation: A Case Report and Literature Review Respirology Case Reports. Dec, 2021 | Pubmed ID: 34765225 Baseline Lung Allograft Dysfunction in Primary Graft Dysfunction Survivors After Lung Transplantation Respiratory Medicine. 11, 2021 | Pubmed ID: 34571454 Sternal Bone Marrow Harvesting and Culturing Techniques from Patients Undergoing Cardiac Surgery Micromachines. Jul, 2021 | Pubmed ID: 34442518 The Effects of Body Mass Index on Long-term Outcomes and Cardiac Remodeling Following Mitral Valve Repair Surgery International Journal of Obesity (2005). 12, 2021 | Pubmed ID: 34373569 Lung Transplantation, Pulmonary Endothelial Inflammation, and Ex-Situ Lung Perfusion: A Review Cells. 06, 2021 | Pubmed ID: 34200413 Atelectasis in Primary Graft Dysfunction Survivors After Lung Transplantation Clinical Transplantation. 07, 2021 | Pubmed ID: 33848359 The Position of the Heart During Normothermic Ex Situ Heart Perfusion is an Important Factor in Preservation and Recovery of Myocardial Function ASAIO Journal (American Society for Artificial Internal Organs : 1992). 11, 2021 | Pubmed ID: 33741785 A Review of the Immune Response Stimulated by Xenogenic Tissue Heart Valves Scandinavian Journal of Immunology. Apr, 2021 | Pubmed ID: 33372305 Impact of Sex on Cardiac Remodeling and Long-term Outcomes, Following Mitral Valve Replacement Journal of Cardiac Surgery. Feb, 2021 | Pubmed ID: 33350520 Association Between Mycoplasma and Ureaplasma Airway Positivity, Ammonia Levels, and Outcomes Post-lung Transplantation: A Prospective Surveillance Study American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 06, 2021 | Pubmed ID: 33179447 Structural Valve Deterioration Is Linked to Increased Immune Infiltrate and Chemokine Expression Journal of Cardiovascular Translational Research. 06, 2021 | Pubmed ID: 33089488 Chest X-ray Sizing for Lung Transplants Reflects Pulmonary Diagnosis and Body Composition and Is Associated With Primary Graft Dysfunction Risk Transplantation. 02, 2021 | Pubmed ID: 32229774 Resveratrol Attenuates Stimulated T-cell Activation and Proliferation: Potential Therapy Against Cellular Rejection in Organ Transplantation American Journal of Clinical and Experimental Immunology. 2020 | Pubmed ID: 33489476 Long-term Outcomes Following Mechanical or Bioprosthetic Aortic Valve Replacement in Young Women CJC Open. Nov, 2020 | Pubmed ID: 33305211 Clinical Transplantation Using Negative Pressure Ventilation Ex Situ Lung Perfusion with Extended Criteria Donor Lungs Nature Communications. 11, 2020 | Pubmed ID: 33188221 Azithromycin Prophylaxis After Lung Transplantation is Associated with Improved Overall Survival The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. 12, 2020 | Pubmed ID: 33041181 The Efficacy of Ice Recrystallization Inhibitors in Rat Lung Cryopreservation Using a Low Cost Technique for Ex Vivo Subnormothermic Lung Perfusion Cryobiology. 12, 2020 | Pubmed ID: 33031822 A Low-Cost Perfusate Alternative for Ex Vivo Lung Perfusion Transplantation Proceedings. Jul, 2020 | Pubmed ID: 32624230 Immunity and Stress Responses Are Induced During Ex Situ Heart Perfusion Circulation. Heart Failure. Jun, 2020 | Pubmed ID: 32498623 The Effects of Body Mass Index on Outcomes for Patients Undergoing Surgical Aortic Valve Replacement BMC Cardiovascular Disorders. May, 2020 | Pubmed ID: 32471345 Current Techniques and the Future of Lung Preservation Cryobiology. Jun, 2020 | Pubmed ID: 32361000 Outcomes Following Bioprosthetic Valve Replacement in Prior Non-cardiac Transplant Recipients Clinical Transplantation. 11, 2019 | Pubmed ID: 31556148 Prospective Validation and Refinement of the APPROACH Cardiovascular Surgical Intensive Care Unit Readmission Score Journal of Critical Care. 12, 2019 | Pubmed ID: 31421527 Total Parenteral Nutrition in Ex Vivo Lung Perfusion: Addressing Metabolism Improves Both Inflammation and Oxygenation American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 12, 2019 | Pubmed ID: 31420938 Continuous Hemodialysis Does Not Improve Graft Function During Ex Vivo Lung Perfusion Over 24 Hours Transplantation Proceedings. Jul - Aug, 2019 | Pubmed ID: 31303418 Myocardial Functional Decline During Prolonged Ex Situ Heart Perfusion The Annals of Thoracic Surgery. 08, 2019 | Pubmed ID: 30872100 Elevated Pre-transplant Left Ventricular End-diastolic Pressure Increases Primary Graft Dysfunction Risk in Double Lung Transplant Recipients The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. 07, 2019 | Pubmed ID: 30850154 Variables Associated With Cardiac Surgical Waitlist Mortality From a Population-Based Cohort The Canadian Journal of Cardiology. 01, 2019 | Pubmed ID: 30595184 Comparison of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Management Strategies Before Cardiac Surgery: A Pilot Randomized Controlled Registry Trial Journal of the American Heart Association. 10, 2018 | Pubmed ID: 30371293 Ex Vivo Perfusion Induces a Time- and Perfusate-dependent Molecular Repair Response in Explanted Porcine Lungs American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Sep, 2018 | Pubmed ID: 30230229 Normothermic Ex-vivo Preservation with the Portable Organ Care System Lung Device for Bilateral Lung Transplantation (INSPIRE): a Randomised, Open-label, Non-inferiority, Phase 3 Study The Lancet. Respiratory Medicine. 05, 2018 | Pubmed ID: 29650408 Baseline Lung Allograft Dysfunction is Associated with Impaired Survival After Double-lung Transplantation The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. 07, 2018 | Pubmed ID: 29602706 Transplantation of Hearts Donated After Circulatory Death Frontiers in Cardiovascular Medicine. 2018 | Pubmed ID: 29487855 Coronary Artery Bypass Surgery Improves Outcomes in Patients With Diabetes and Left Ventricular Dysfunction Journal of the American College of Cardiology. Feb, 2018 | Pubmed ID: 29471931 Lung Transplantation from Hepatitis C Viremic Donors to Uninfected Recipients American Journal of Respiratory and Critical Care Medicine. 06, 2018 | Pubmed ID: 29412687 Body Mass Index in Lung Transplantation: Every Unit Counts The Journal of Thoracic and Cardiovascular Surgery. Apr, 2018 | Pubmed ID: 29409608 Steroids Limit Myocardial Edema During Ex Vivo Perfusion of Hearts Donated After Circulatory Death The Annals of Thoracic Surgery. Jun, 2018 | Pubmed ID: 29382512 A Decrease in Hypoxic Pulmonary Vasoconstriction Correlates With Increased Inflammation During Extended Normothermic Ex Vivo Lung Perfusion Artificial Organs. Mar, 2018 | Pubmed ID: 29266272 Negative Pressure Ventilation Decreases Inflammation and Lung Edema During Normothermic Ex-vivo Lung Perfusion The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation. Apr, 2018 | Pubmed ID: 29103845 Inhibition of Pyruvate Dehydrogenase Kinase Improves Pulmonary Arterial Hypertension in Genetically Susceptible Patients Science Translational Medicine. Oct, 2017 | Pubmed ID: 29070699 Feasibility of Lung Transplantation From Donation After Circulatory Death Donors Following Portable Ex Vivo Lung Perfusion: A Pilot Study Transplantation Proceedings. Oct, 2017 | Pubmed ID: 28923643 Clinical and Angiographic Outcomes in Coronary Artery Bypass Surgery with Multiple Versus Single Distal Target Grafts The Heart Surgery Forum. 08, 2017 | Pubmed ID: 28846526 Extended Bridge to Heart and Lung Transplantation Using Pumpless Extracorporeal Lung Assist The Canadian Journal of Cardiology. 07, 2017 | Pubmed ID: 28579162 Hospital Variation in Treatment and Outcomes in Acute Coronary Syndromes: Insights from the Alberta Contemporary Acute Coronary Syndrome Patients Invasive Treatment Strategies (COAPT) Study International Journal of Cardiology. Aug, 2017 | Pubmed ID: 28495247 Differences in Short- and Long-Term Mortality Associated With BMI Following Coronary Revascularization Journal of the American Heart Association. Apr, 2017 | Pubmed ID: 28411242 Aorto-Right Atrial Fistula After Sutureless Valve Implantation The Canadian Journal of Cardiology. 05, 2017 | Pubmed ID: 28347580 Body Mass Index Is Associated With Differential Rates of Coronary Revascularization After Cardiac Catheterization The Canadian Journal of Cardiology. 06, 2017 | Pubmed ID: 28342570 A Leukocyte Filter Does Not Provide Further Benefit During Ex Vivo Lung Perfusion ASAIO Journal (American Society for Artificial Internal Organs : 1992). Sep/Oct, 2017 | Pubmed ID: 28234641 Impact of Obesity on Heart and Lung Transplantation: Does Pre-Transplant Obesity Affect Outcomes? Transplantation Proceedings. Mar, 2017 | Pubmed ID: 28219596 Impact of Reperfusion Calcium and PH on the Resuscitation of Hearts Donated After Circulatory Death The Annals of Thoracic Surgery. Jan, 2017 | Pubmed ID: 27526656 Extracorporeal Lung Support As a Bridge to Diagnosis of Pulmonary Tumor Embolism Case Reports in Pulmonology. 2016 | Pubmed ID: 28070437 Improving Long-term Survival by Preventing Early Complications After Lung Transplantation: Can We Prevent Ripples by Keeping Pebbles out of the Water? The Journal of Thoracic and Cardiovascular Surgery. Apr, 2016 | Pubmed ID: 26832212 Clinical and Angiographic Outcomes Associated with Surgical Revascularization of Angiographically Borderline 50-69% Coronary Artery Stenoses European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. May, 2016 | Pubmed ID: 26825107 The Evolving Potential for Pediatric Ex Vivo Lung Perfusion Pediatric Transplantation. Feb, 2016 | Pubmed ID: 26694514 Assessment of Donor Heart Viability During Ex Vivo Heart Perfusion Canadian Journal of Physiology and Pharmacology. Oct, 2015 | Pubmed ID: 26317524 2-Methoxyestradiol: A Hormonal Metabolite Modulates Stimulated T-Cells Function and Proliferation Transplantation Proceedings. Jul-Aug, 2015 | Pubmed ID: 26293097 Compliance Trumps Oxygenation: Predicting Quality with Ex vivo Lung Perfusion The Journal of Thoracic and Cardiovascular Surgery. Nov, 2015 | Pubmed ID: 26242840 Canada's Longest Experience with Extracorporeal Membrane Oxygenation As a Bridge to Lung Transplantation: a Case Report Transplantation Proceedings. Jan-Feb, 2015 | Pubmed ID: 25645800 Successful Repair of Donation After Circulatory Death Lungs with Large Pulmonary Embolus Using the Lung Organ Care System for Ex Vivo Thrombolysis and Subsequent Clinical Transplantation Transplantation. Jan, 2015 | Pubmed ID: 25525922 Lung Transplantation from Donors After Circulatory Death Using Portable Ex Vivo Lung Perfusion Canadian Respiratory Journal. Jan-Feb, 2015 | Pubmed ID: 25379654 Successful Transplantation of Extended Criteria Lungs After Prolonged Ex Vivo Lung Perfusion Performed on a Portable Device Transplant International : Official Journal of the European Society for Organ Transplantation. Feb, 2015 | Pubmed ID: 25284600 Predicting Cardiovascular Intensive Care Unit Readmission After Cardiac Surgery: Derivation and Validation of the Alberta Provincial Project for Outcomes Assessment in Coronary Heart Disease (APPROACH) Cardiovascular Intensive Care Unit Clinical Prediction Model from a Registry Cohort of 10,799 Surgical Cases Critical Care (London, England). Nov, 2014 | Pubmed ID: 25408082 A Metabolic Remodeling in Right Ventricular Hypertrophy is Associated with Decreased Angiogenesis and a Transition from a Compensated to a Decompensated State in Pulmonary Hypertension Journal of Molecular Medicine (Berlin, Germany). Nov, 2013 | Pubmed ID: 23846254 Endothelin Axis is Upregulated in Human and Rat Right Ventricular Hypertrophy Circulation Research. Jan, 2013 | Pubmed ID: 23233754 A Dynamic and Chamber-specific Mitochondrial Remodeling in Right Ventricular Hypertrophy Can Be Therapeutically Targeted The Journal of Thoracic and Cardiovascular Surgery. Jul, 2008 | Pubmed ID: 18603070 CD36 Expression Contributes to Age-induced Cardiomyopathy in Mice Circulation. Nov, 2007 | Pubmed ID: 17967771 Phosphodiesterase Type 5 is Highly Expressed in the Hypertrophied Human Right Ventricle, and Acute Inhibition of Phosphodiesterase Type 5 Improves Contractility Circulation. Jul, 2007 | Pubmed ID: 17606845 An Anesthesiologist's Guide to Hypoxic Pulmonary Vasoconstriction: Implications for Managing Single-lung Anesthesia and Atelectasis Current Opinion in Anaesthesiology. Feb, 2006 | Pubmed ID: 16547431 Is Mitral Valve Surgery Safe in Octogenarians? European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery. Jul, 2005 | Pubmed ID: 15982591 A Comparative Analysis of Outcome After Heart Transplantation in Patients Aged 60 Years and Older: the University of Alberta Experience Journal of Cardiac Surgery. Nov-Dec, 2004 | Pubmed ID: 15548193 Mechanical Circulatory Support As a Bridge to Lung Transplantation: A Single Canadian Institution Review Canadian Respiratory Journal. | Pubmed ID: 28951661 Left Ventricular End-diastolic Pressure Predicts Survival in Coronary Artery Bypass Graft Surgery Patients The Annals of Thoracic Surgery. | Pubmed ID: 24406240 Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism Keir A. Forgie1,2, Nicholas Fialka3, Max Buchko1,2, Sayed Himmat4, Sanaz Hatami4, Xiao Qi4, Xiuhua Wang4, Katie-Marie Buswell5, Ryan Edgar5, Darren H. Freed1,2,6,7, Jayan Nagendran1,2,6,7 1Division of Cardiac Surgery, Department of Surgery, Faculty of Medicine, University of Alberta, 2Mazankowski Alberta Heart Institute, 3Faculty of Medicine and Dentistry, University of Alberta, 4Department of Surgery, Faculty of Medicine, University of Alberta, 5Ray Rajotte Surgical-Medical Research Institute (SMRI), University of Alberta, 6Alberta Transplant Institute, 7Canadian Donation and Transplantation Research Program JoVE 62982 Médecine Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP Keir A. Forgie1,2, Nicholas Fialka3, Mubashir Khan4, Max Buchko1,2, Sanaz Hatami4, Sayed Himmat4, Xiao Qi4, Xiuhua Wang4, Katie-Marie Buswell5, Ryan Edgar5, Daina Domahidi5, Darren H. Freed1,2,6,7, Jayan Nagendran1,2,6,7 1Division of Cardiac Surgery, Department of Surgery, Faculty of Medicine, University of Alberta, 2Mazankowski Alberta Heart Institute, 3Faculty of Medicine and Dentistry, University of Alberta, 4Department of Surgery, Faculty of Medicine, University of Alberta, 5Ray Rajotte Surgical-Medical Research Institute (SMRI), University of Alberta, 6Alberta Transplant Institute, 7Canadian Donation and Transplantation Research Program JoVE 62979 Médecine Normothermic Ex Situ Heart Perfusion in Working Mode: Assessment of Cardiac Function and Metabolism Sanaz Hatami1, Christopher W. White1, Martin Ondrus1, Xiao Qi1, Max Buchko1, Sayed Himmat1, Lily Lin2, Katie Cameron3, David Nobes4, Hyun-Joong Chung5, Jayan Nagendran1,6, Darren H. Freed1,3,6,7 1Department of Surgery, Faculty of Medicine, University of Alberta, 2Department of Pediatrics, Faculty of Medicine, University of Alberta, 3Department of Biomedical Engineering, Faculty of Medicine, University of Alberta, 4Department of Mechanical Engineering, Faculty of Engineering, University of Alberta, 5Department of Chemical and Materials Engineering, Faculty of Engineering, University of Alberta, 6Canadian National Transplant Research Program, 7Department of Physiology, Faculty of Medicine, University of Alberta JoVE 58430 Médecine
Normothermic Negative Pressure Ventilation Ex Situ Lung Perfusion: Evaluation of Lung Function and Metabolism Keir A. Forgie1,2, Nicholas Fialka3, Max Buchko1,2, Sayed Himmat4, Sanaz Hatami4, Xiao Qi4, Xiuhua Wang4, Katie-Marie Buswell5, Ryan Edgar5, Darren H. Freed1,2,6,7, Jayan Nagendran1,2,6,7 1Division of Cardiac Surgery, Department of Surgery, Faculty of Medicine, University of Alberta, 2Mazankowski Alberta Heart Institute, 3Faculty of Medicine and Dentistry, University of Alberta, 4Department of Surgery, Faculty of Medicine, University of Alberta, 5Ray Rajotte Surgical-Medical Research Institute (SMRI), University of Alberta, 6Alberta Transplant Institute, 7Canadian Donation and Transplantation Research Program JoVE 62982 Médecine
Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP Keir A. Forgie1,2, Nicholas Fialka3, Mubashir Khan4, Max Buchko1,2, Sanaz Hatami4, Sayed Himmat4, Xiao Qi4, Xiuhua Wang4, Katie-Marie Buswell5, Ryan Edgar5, Daina Domahidi5, Darren H. Freed1,2,6,7, Jayan Nagendran1,2,6,7 1Division of Cardiac Surgery, Department of Surgery, Faculty of Medicine, University of Alberta, 2Mazankowski Alberta Heart Institute, 3Faculty of Medicine and Dentistry, University of Alberta, 4Department of Surgery, Faculty of Medicine, University of Alberta, 5Ray Rajotte Surgical-Medical Research Institute (SMRI), University of Alberta, 6Alberta Transplant Institute, 7Canadian Donation and Transplantation Research Program JoVE 62979 Médecine
Normothermic Ex Situ Heart Perfusion in Working Mode: Assessment of Cardiac Function and Metabolism Sanaz Hatami1, Christopher W. White1, Martin Ondrus1, Xiao Qi1, Max Buchko1, Sayed Himmat1, Lily Lin2, Katie Cameron3, David Nobes4, Hyun-Joong Chung5, Jayan Nagendran1,6, Darren H. Freed1,3,6,7 1Department of Surgery, Faculty of Medicine, University of Alberta, 2Department of Pediatrics, Faculty of Medicine, University of Alberta, 3Department of Biomedical Engineering, Faculty of Medicine, University of Alberta, 4Department of Mechanical Engineering, Faculty of Engineering, University of Alberta, 5Department of Chemical and Materials Engineering, Faculty of Engineering, University of Alberta, 6Canadian National Transplant Research Program, 7Department of Physiology, Faculty of Medicine, University of Alberta JoVE 58430 Médecine