Jian Wu Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences Fudan University Biography Publications Institution JoVE Articles Jian Wu has not added a biography. If you are Jian Wu and would like to personalize this page please email our Author Liaison for assistance. Publications CXCR6 Mediates Pressure Overload-Induced Aortic Stiffness by Increasing Macrophage Recruitment and Reducing Exosome-miRNA29b Journal of Cardiovascular Translational Research. Aug, 2022 | Pubmed ID: 36018423 GPM6A Expression is Suppressed in Hepatocellular Carcinoma Through MiRNA-96 Production Laboratory Investigation; a Journal of Technical Methods and Pathology. Aug, 2022 | Pubmed ID: 35918602 Editorial: Mitochondrial Metabolism in Ischemic Heart Disease Frontiers in Cardiovascular Medicine. 2022 | Pubmed ID: 35833188 Aldehyde Dehydrogenase 2 (ALDH2) Elicits Protection Against Pulmonary Hypertension Via Inhibition of ERK1/2-Mediated Autophagy Oxidative Medicine and Cellular Longevity. 2022 | Pubmed ID: 35770049 Blood Flow and Perfusion Lateralization in Border Zone Infarct Using 4D Flow and Arterial Spin Labeling Neuroradiology. May, 2022 | Pubmed ID: 35644897 Differential MRNA Expression and Circular RNA-Based Competitive Endogenous RNA Networks in the Three Stages of Heart Failure in Transverse Aortic Constriction Mice Frontiers in Physiology. 2022 | Pubmed ID: 35330931 Understanding Initiation and Progression of Hepatocellular Carcinoma Through Single Cell Sequencing Biochimica Et Biophysica Acta. Reviews on Cancer. 05, 2022 | Pubmed ID: 35304295 Updates on Novel Pharmacotherapeutics for the Treatment of Nonalcoholic Steatohepatitis Acta Pharmacologica Sinica. May, 2022 | Pubmed ID: 35190696 PCSK9 Participates in Oxidized-low Density Lipoprotein-induced Myocardial Injury Through Mitochondrial Oxidative Stress and Drp1-mediated Mitochondrial Fission Clinical and Translational Medicine. 02, 2022 | Pubmed ID: 35184412 Non-Invasive Local Acoustic Therapy Ameliorates Diabetic Heart Fibrosis by Suppressing ACE-Mediated Oxidative Stress and Inflammation in Cardiac Fibroblasts Cardiovascular Drugs and Therapy. 06, 2022 | Pubmed ID: 35156147 Janus Membranes with Asymmetric Cellular Adhesion Behaviors for Regenerating Eardrum Perforation Journal of Materials Chemistry. B. 04, 2022 | Pubmed ID: 35138320 Histamine Deficiency Promotes Myofibroblasts Transformation from HDC-Expressing CD11b Myeloid Cells in Injured Hearts Post Myocardial Infarction Journal of Cardiovascular Translational Research. 06, 2022 | Pubmed ID: 34734351 AT1 Receptor Blocker Inhibits HMGB1 Expression in Pressure Overload-induced Acute Cardiac Dysfunction by Suppressing the MAPK/NF-κB Signaling Pathway Clinical and Experimental Hypertension (New York, N.Y. : 1993). Jan, 2022 | Pubmed ID: 34704526 Oxidized LDL but Not Angiotensin II Induces Cardiomyocyte Hypertrophic Responses Through the Interaction Between LOX-1 and AT Receptors Journal of Molecular and Cellular Cardiology. 01, 2022 | Pubmed ID: 34555408 Advancements in Detection of SARS-CoV-2 Infection for Confronting COVID-19 Pandemics Laboratory Investigation; a Journal of Technical Methods and Pathology. 01, 2022 | Pubmed ID: 34497366 Involvement of Endoplasmic Reticulum Stress-Mediated Activation of C/EBP Homologous Protein in Aortic Regurgitation-Induced Cardiac Remodeling in Mice Journal of Cardiovascular Translational Research. 04, 2022 | Pubmed ID: 34426929 Elevated Wnt2 and Wnt4 Activate NF-κB Signaling to Promote Cardiac Fibrosis by Cooperation of Fzd4/2 and LRP6 Following Myocardial Infarction EBioMedicine. Dec, 2021 | Pubmed ID: 34911029 Artificial Intelligence: A Powerful Paradigm for Scientific Research Innovation (Cambridge (Mass.)). Nov, 2021 | Pubmed ID: 34877560 M6A Demethylase FTO Attenuates Cardiac Dysfunction by Regulating Glucose Uptake and Glycolysis in Mice with Pressure Overload-induced Heart Failure Signal Transduction and Targeted Therapy. 11, 2021 | Pubmed ID: 34728610 Muscle-specific Programmed Cell Death 5 Deletion Attenuates Cardiac Aging International Journal of Cardiology. Dec, 2021 | Pubmed ID: 34710491 Comprehensive Pharmacogenomics Characterization of Temozolomide Response in Gliomas European Journal of Pharmacology. Dec, 2021 | Pubmed ID: 34678239 Novel Approaches to Intervene Gut Microbiota in the Treatment of Chronic Liver Diseases FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 10, 2021 | Pubmed ID: 34473374 LC-MS-based Lipidomic Analysis in Distinguishing Patients with Nonalcoholic Steatohepatitis from Nonalcoholic Fatty Liver Hepatobiliary & Pancreatic Diseases International : HBPD INT. Oct, 2021 | Pubmed ID: 34256994 Donafenib Versus Sorafenib in First-Line Treatment of Unresectable or Metastatic Hepatocellular Carcinoma: A Randomized, Open-Label, Parallel-Controlled Phase II-III Trial Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 09, 2021 | Pubmed ID: 34185551 A Porcine Model of Heart Failure With Preserved Ejection Fraction Induced by Chronic Pressure Overload Characterized by Cardiac Fibrosis and Remodeling Frontiers in Cardiovascular Medicine. 2021 | Pubmed ID: 34150870 Sintilimab Plus a Bevacizumab Biosimilar (IBI305) Versus Sorafenib in Unresectable Hepatocellular Carcinoma (ORIENT-32): a Randomised, Open-label, Phase 2-3 Study The Lancet. Oncology. 07, 2021 | Pubmed ID: 34143971 Hypertrophic Preconditioning Cardioprotection After Myocardial Ischaemia/reperfusion Injury Involves ALDH2-dependent Metabolism Modulation Redox Biology. 07, 2021 | Pubmed ID: 33910156 CanDriS: Posterior Profiling of Cancer-driving Sites Based on Two-component Evolutionary Model Briefings in Bioinformatics. 09, 2021 | Pubmed ID: 33876217 Caspase-1 Abrogates the Salutary Effects of Hypertrophic Preconditioning in Pressure Overload Hearts Via IL-1β and IL-18 Frontiers in Molecular Biosciences. 2021 | Pubmed ID: 33842546 Predictors and Long-term Prognosis of Left Ventricular Aneurysm in Patients with Acute Anterior Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention in the Contemporary Era Journal of Thoracic Disease. Mar, 2021 | Pubmed ID: 33841961 Plasma Exosome-Derived Sentrin SUMO-Specific Protease 1: A Prognostic Biomarker in Patients With Osteosarcoma Frontiers in Oncology. 2021 | Pubmed ID: 33791211 Efficacy and Safety of a Selective URAT1 Inhibitor SHR4640 in Chinese Subjects with Hyperuricaemia: a Randomized Controlled Phase II Study Rheumatology (Oxford, England). 11, 2021 | Pubmed ID: 33693494 Activation of CXCL16/CXCR6 Axis Aggravates Cardiac Ischemia/reperfusion Injury by Recruiting the IL-17a-producing CD1d T Cells Clinical and Translational Medicine. 02, 2021 | Pubmed ID: 33634988 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th Edition) Autophagy. Feb, 2021 | Pubmed ID: 33634751 Aged Monkeys Fed a High-Fat/High-Sugar Diet Recapitulate Metabolic Disorders and Cardiac Contractile Dysfunction Journal of Cardiovascular Translational Research. 10, 2021 | Pubmed ID: 33591467 2020 Expert Consensus Statement on Neuro-protection After Cardiac Arrest in China Annals of Translational Medicine. Jan, 2021 | Pubmed ID: 33569477 Thermo-responsive Polymer Encapsulated Gold Nanorods for Single Continuous Wave Laser-induced Photodynamic/photothermal Tumour Therapy Journal of Nanobiotechnology. Feb, 2021 | Pubmed ID: 33557807 NLRP3 Deficiency Did Not Attenuate NASH Development Under High Fat Calorie Diet Plus High Fructose and Glucose in Drinking Water Laboratory Investigation; a Journal of Technical Methods and Pathology. 05, 2021 | Pubmed ID: 33526807 Serum Lipocalin-2 is a Potential Biomarker for the Clinical Diagnosis of Nonalcoholic Steatohepatitis Clinical and Molecular Hepatology. Apr, 2021 | Pubmed ID: 33465844 Angiotensin II Increases HMGB1 Expression in the Myocardium Through AT1 and AT2 Receptors When Under Pressure Overload International Heart Journal. Jan, 2021 | Pubmed ID: 33455985 Hedgehog Signaling, a Critical Pathway Governing the Development and Progression of Hepatocellular Carcinoma Cells. 01, 2021 | Pubmed ID: 33440657 Low-density Lipoprotein Receptor-related Protein 6 Regulates Cardiomyocyte-derived Paracrine Signaling to Ameliorate Cardiac Fibrosis Theranostics. 2021 | Pubmed ID: 33391533 Novel Aptasensor-based Assay of Sonic Hedgehog Ligand for Detection of Portal Vein Invasion of Hepatocellular Carcinoma Biosensors & Bioelectronics. Feb, 2021 | Pubmed ID: 33257185 Camrelizumab in Combination with Apatinib in Patients with Advanced Hepatocellular Carcinoma (RESCUE): A Nonrandomized, Open-label, Phase II Trial Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 02, 2021 | Pubmed ID: 33087333 Epidemiological and Clinical Characteristics of 70 Cases of Coronavirus Disease and Concomitant Hepatitis B Virus Infection: A Multicentre Descriptive Study Journal of Viral Hepatitis. 01, 2021 | Pubmed ID: 32929826 Variations in Energy Metabolism Precede Alterations in Cardiac Structure and Function in Hypertrophic Preconditioning Frontiers in Cardiovascular Medicine. 2020 | Pubmed ID: 33426002 Disruption of STAT6 Signal Promotes Cardiac Fibrosis Through the Mobilization and Transformation of CD11b Immature Myeloid Cells Frontiers in Physiology. 2020 | Pubmed ID: 33192584 Immunotherapy for Advanced Hepatocellular Carcinoma, Where Are We? Biochimica Et Biophysica Acta. Reviews on Cancer. 12, 2020 | Pubmed ID: 33007432 GPR91, a Critical Signaling Mechanism in Modulating Pathophysiologic Processes in Chronic Illnesses FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 10, 2020 | Pubmed ID: 32812686 Estrogen-Induced Stromal FGF18 Promotes Proliferation and Invasion of Endometrial Carcinoma Cells Through ERK and Akt Signaling Cancer Management and Research. 2020 | Pubmed ID: 32801905 Alpha-lipoic Acid Protects Against Pressure Overload-induced Heart Failure Via ALDH2-dependent Nrf1-FUNDC1 Signaling Cell Death & Disease. 07, 2020 | Pubmed ID: 32732978 Advances in Detection of Infectious Agents by Aptamer-based Technologies Emerging Microbes & Infections. Dec, 2020 | Pubmed ID: 32623963 Hypoxia-challenged MSC-derived Exosomes Deliver MiR-210 to Attenuate Post-infarction Cardiac Apoptosis Stem Cell Research & Therapy. 06, 2020 | Pubmed ID: 32513270 Liver Diseases in COVID-19: Etiology, Treatment and Prognosis World Journal of Gastroenterology. May, 2020 | Pubmed ID: 32476793 Fuzheng Huayu Capsule Attenuates Hepatic Fibrosis by Inhibiting Activation of Hepatic Stellate Cells Evidence-based Complementary and Alternative Medicine : ECAM. 2020 | Pubmed ID: 32454856 Left Ventricular Response in the Transition from Hypertrophy to Failure Recapitulates Distinct Roles of Akt, β-arrestin-2, and CaMKII in Mice with Aortic Regurgitation Annals of Translational Medicine. Mar, 2020 | Pubmed ID: 32309366 Slit2 Protects Hearts Against Ischemia-Reperfusion Injury by Inhibiting Inflammatory Responses and Maintaining Myofilament Contractile Properties Frontiers in Physiology. 2020 | Pubmed ID: 32292352 Exercise Improves Cardiac Function and Glucose Metabolism in Mice with Experimental Myocardial Infarction Through Inhibiting HDAC4 and Upregulating GLUT1 Expression Basic Research in Cardiology. 03, 2020 | Pubmed ID: 32236769 Hepalatide Ameliorated Progression of Nonalcoholic Steatohepatitis in Mice Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Jun, 2020 | Pubmed ID: 32200254 Disruption of Histamine/HR Signaling Pathway Represses Cardiac Differentiation and Maturation of Human Induced Pluripotent Stem Cells Stem Cell Research & Therapy. 03, 2020 | Pubmed ID: 32127042 Hedgehog Signalling Mediates Drug Resistance Through Targeting TAP1 in Hepatocellular Carcinoma Journal of Cellular and Molecular Medicine. 04, 2020 | Pubmed ID: 32108992 Pharmacokinetics, Pharmacodynamics and Safety of Belimumab in Chinese Patients with Systemic Lupus Erythematosus: A Phase I, Open-Label Study Rheumatology and Therapy. Mar, 2020 | Pubmed ID: 31953740 Succinate-GPR-91 Receptor Signalling is Responsible for Nonalcoholic Steatohepatitis-associated Fibrosis: Effects of DHA Supplementation Liver International : Official Journal of the International Association for the Study of the Liver. 04, 2020 | Pubmed ID: 31903720 A Novel Rhynchophylline Analog, Y396, Inhibits Endothelial Dysfunction Induced by Oxidative Stress in Diabetes Through Epidermal Growth Factor Receptor Antioxidants & Redox Signaling. 04, 2020 | Pubmed ID: 31892280 Gender Differences in Cardiac Hypertrophy Journal of Cardiovascular Translational Research. 02, 2020 | Pubmed ID: 31418109 DeepHLApan: A Deep Learning Approach for Neoantigen Prediction Considering Both HLA-Peptide Binding and Immunogenicity Frontiers in Immunology. 2019 | Pubmed ID: 31736974 Sequence Characterization of RET in 117 Chinese Hirschsprung Disease Families Identifies a Large Burden of De Novo and Parental Mosaic Mutations Orphanet Journal of Rare Diseases. 10, 2019 | Pubmed ID: 31666091 Lipoprotein Receptor-related Protein 6 is Required to Maintain Intercalated Disk Integrity Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Dec, 2019 | Pubmed ID: 31609038 UBE2T Promotes Proliferation Via G2/M Checkpoint in Hepatocellular Carcinoma Cancer Management and Research. 2019 | Pubmed ID: 31571992 HMGB1 Enhances Mechanical Stress-induced Cardiomyocyte Hypertrophy In vitro Via the RAGE/ERK1/2 Signaling Pathway International Journal of Molecular Medicine. Sep, 2019 | Pubmed ID: 31524228 Comprehensive Analysis of Long Non‑coding RNA‑messenger RNA‑microRNA Co‑expression Network Identifies Cell Cycle‑related LncRNA in Hepatocellular Carcinoma International Journal of Molecular Medicine. Nov, 2019 | Pubmed ID: 31485608 Cas12aVDet: A CRISPR/Cas12a-Based Platform for Rapid and Visual Nucleic Acid Detection Analytical Chemistry. 10, 2019 | Pubmed ID: 31460749 Loss of Rubicon Ameliorates Doxorubicin-induced Cardiotoxicity Through Enhancement of Mitochondrial Quality International Journal of Cardiology. 12, 2019 | Pubmed ID: 31439425 VEGFR Endocytosis Regulates the Angiogenesis in a Mouse Model of Hindlimb Ischemia Journal of Thoracic Disease. May, 2019 | Pubmed ID: 31285877 ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis After Acute Myocardial Infarction Through Downregulating the RIP3-CaMKII Signaling Pathway Oxidative Medicine and Cellular Longevity. 2019 | Pubmed ID: 31281585 Targeting the MTOR Regulatory Network in Hepatocellular Carcinoma: Are We Making Headway? Biochimica Et Biophysica Acta. Reviews on Cancer. 04, 2019 | Pubmed ID: 30951815 Interleukin-35 Promotes Macrophage Survival and Improves Wound Healing After Myocardial Infarction in Mice Circulation Research. 04, 2019 | Pubmed ID: 30832557 SIRT5 Deficiency Suppresses Mitochondrial ATP Production and Promotes AMPK Activation in Response to Energy Stress PloS One. 2019 | Pubmed ID: 30759120 Impaired Mitophagy Triggers NLRP3 Inflammasome Activation During the Progression from Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis Laboratory Investigation; a Journal of Technical Methods and Pathology. 06, 2019 | Pubmed ID: 30700851 BLM Can Regulate Cataract Progression by Influencing Cell Vitality and Apoptosis Experimental Eye Research. 01, 2019 | Pubmed ID: 30227115 Restoration of FBP1 Suppressed Snail-induced Epithelial to Mesenchymal Transition in Hepatocellular Carcinoma Cell Death & Disease. 11, 2018 | Pubmed ID: 30429463 Deletion of Exon 4 in LAMA2 is the Most Frequent Mutation in Chinese Patients with Laminin α2-related Muscular Dystrophy Scientific Reports. 10, 2018 | Pubmed ID: 30301903 Predictors and Prognosis of Left Ventricular Thrombus in Post-myocardial Infarction Patients with Left Ventricular Dysfunction After Percutaneous Coronary Intervention Journal of Thoracic Disease. Aug, 2018 | Pubmed ID: 30233865 Risk Factors for Lower Limb Deep Vein Thrombosis in Patients With Single-Level Lumbar Fusion: A Prospective Study of 710 Cases Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. Dec, 2018 | Pubmed ID: 30200770 MicroRNA-449a Suppresses Hepatocellular Carcinoma Cell Growth Via G1 Phase Arrest and the HGF/MET C-Met Pathway Hepatobiliary & Pancreatic Diseases International : HBPD INT. Aug, 2018 | Pubmed ID: 30108016 Evaluation of the Performance of Serum MiRNAs As Normalizers in MicroRNA Studies Focused on Cardiovascular Disease Journal of Thoracic Disease. May, 2018 | Pubmed ID: 29997921 Heat-shock Transcription Factor 1 is Critically Involved in the Ischaemia-induced Cardiac Hypertrophy Via JAK2/STAT3 Pathway Journal of Cellular and Molecular Medicine. 09, 2018 | Pubmed ID: 29992755 The Diagnostic Values of Circulating MiRNAs for Hypertension and Bioinformatics Analysis Bioscience Reports. 08, 2018 | Pubmed ID: 29961674 Characterization of a Murine Nonalcoholic Steatohepatitis Model Induced by High Fat High Calorie Diet Plus Fructose and Glucose in Drinking Water Laboratory Investigation; a Journal of Technical Methods and Pathology. 09, 2018 | Pubmed ID: 29959418 Aldehyde Dehydrogenase 2 Activation Ameliorates CCl -induced Chronic Liver Fibrosis in Mice by Up-regulating Nrf2/HO-1 Antioxidant Pathway Journal of Cellular and Molecular Medicine. Aug, 2018 | Pubmed ID: 29799157 MiR-125b-5p is Involved in Oxygen and Glucose Deprivation Injury in PC-12 Cells Via CBS/HS Pathway Nitric Oxide : Biology and Chemistry. 08, 2018 | Pubmed ID: 29777774 MicroRNA-378 Suppresses Myocardial Fibrosis Through a Paracrine Mechanism at the Early Stage of Cardiac Hypertrophy Following Mechanical Stress Theranostics. 2018 | Pubmed ID: 29721099 HSF1 Deficiency Accelerates the Transition from Pressure Overload-induced Cardiac Hypertrophy to Heart Failure Through Endothelial MiR-195a-3p-mediated Impairment of Cardiac Angiogenesis Journal of Molecular and Cellular Cardiology. 05, 2018 | Pubmed ID: 29626503 Reactivation of Hepatitis B After Liver Transplantation: Current Knowledge, Molecular Mechanisms and Implications in Management World Journal of Hepatology. Mar, 2018 | Pubmed ID: 29599899 Trichostatin A Inhibits the Activation of Hepatic Stellate Cells by Increasing C/EBP-α Acetylation in Vivo and in Vitro Scientific Reports. 03, 2018 | Pubmed ID: 29535398 Peroxiredoxin 1, Restraining Cell Migration and Invasion, is Involved in Hepatocellular Carcinoma Recurrence Journal of Digestive Diseases. Mar, 2018 | Pubmed ID: 29377617 Interfering RNA Against PKC-α Inhibits TNF-α-induced IPR1 Expression and Improves Glomerular Filtration Rate in Rats with Fulminant Hepatic Failure American Journal of Physiology. Renal Physiology. 05, 2018 | Pubmed ID: 29357415 Riboflavin Attenuates Myocardial Injury Via LSD1-mediated Crosstalk Between Phospholipid Metabolism and Histone Methylation in Mice with Experimental Myocardial Infarction Journal of Molecular and Cellular Cardiology. 02, 2018 | Pubmed ID: 29325932 Differential Cardiac Hypertrophy and Signaling Pathways in Pressure Versus Volume Overload American Journal of Physiology. Heart and Circulatory Physiology. 03, 2018 | Pubmed ID: 29196344 MiR-17-5p Enhances Pancreatic Cancer Proliferation by Altering Cell Cycle Profiles Via Disruption of RBL2/E2F4-repressing Complexes Cancer Letters. 01, 2018 | Pubmed ID: 28987387 Ryanodine Receptor Type 2 Plays a Role in the Development of Cardiac Fibrosis Under Mechanical Stretch Through TGFβ-1 International Heart Journal. Dec, 2017 | Pubmed ID: 29162778 Effect of Mono-2-ethyhexyl Phthalate on DNA Methylation in Human Prostate Cancer LNCaP Cells Biomedical and Environmental Sciences : BES. Sep, 2017 | Pubmed ID: 29081338 Pre-B Acute Lymphoblastic Leukemia with T(1;19) in an Adult Initially Presenting As Hematuria and Bilateral Renal Enlargement: A case Report and Literature Review Clinical Nephrology. Case Studies. 2017 | Pubmed ID: 29043149 Activation of Pluripotent Genes in Hepatic Progenitor Cells in the Transition of Nonalcoholic Steatohepatitis to Pre-malignant Lesions Laboratory Investigation; a Journal of Technical Methods and Pathology. 10, 2017 | Pubmed ID: 28869588 Sirtuin 3 Deficiency Accelerates Hypertensive Cardiac Remodeling by Impairing Angiogenesis Journal of the American Heart Association. Aug, 2017 | Pubmed ID: 28862956 Novel Rhynchophylline Analogues As Microvascular Relaxation Agents for the Treatment of Microvascular Dysfunction Caused by Diabetes European Journal of Medicinal Chemistry. Oct, 2017 | Pubmed ID: 28846966 JCAD Promotes Progression of Nonalcoholic Steatohepatitis to Liver Cancer by Inhibiting LATS2 Kinase Activity Cancer Research. 10, 2017 | Pubmed ID: 28775168 Drug Depot-anchoring Hydrogel: A Self-assembling Scaffold for Localized Drug Release and Enhanced Stem Cell Differentiation Journal of Controlled Release : Official Journal of the Controlled Release Society. 09, 2017 | Pubmed ID: 28694033 Atherosclerosis and the Hydrogen Sulfide Signaling Pathway - Therapeutic Approaches to Disease Prevention Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2017 | Pubmed ID: 28641276 Ultrasound Biomicroscopy Validation of a Murine Model of Cardiac Hypertrophic Preconditioning: Comparison with a Hemodynamic Assessment American Journal of Physiology. Heart and Circulatory Physiology. Jul, 2017 | Pubmed ID: 28455286 Cardioprotection by Mild Hypothermia Is Abolished in Aged Mice Therapeutic Hypothermia and Temperature Management. Dec, 2017 | Pubmed ID: 28445087 A Genome-wide Association Study Identifies Six Novel Risk Loci for Primary Biliary Cholangitis Nature Communications. 04, 2017 | Pubmed ID: 28425483 Hedgehog Signaling Pathway Affects the Sensitivity of Hepatoma Cells to Drug Therapy Through the ABCC1 Transporter Laboratory Investigation; a Journal of Technical Methods and Pathology. 07, 2017 | Pubmed ID: 28414325 Generation of Enhanced Definitive Endoderm from Human Embryonic Stem Cells Under an Albumin/insulin-free and Chemically Defined Condition Life Sciences. Apr, 2017 | Pubmed ID: 28342773 Palmitic Acid Elicits Hepatic Stellate Cell Activation Through Inflammasomes and Hedgehog Signaling Life Sciences. May, 2017 | Pubmed ID: 28322865 UVRAG Deficiency Exacerbates Doxorubicin-Induced Cardiotoxicity Scientific Reports. 02, 2017 | Pubmed ID: 28225086 Heat Shock Transcription Factor 1 Protects Against Pressure Overload-induced Cardiac Fibrosis Via Smad3 Journal of Molecular Medicine (Berlin, Germany). 04, 2017 | Pubmed ID: 28091697 Genome-wide Association Study: New Genetic Insights into HBV/HCV-related Hepatocellular Carcinoma Genomes Scandinavian Journal of Gastroenterology. Feb, 2017 | Pubmed ID: 27797287 Alginate Oligosaccharide Prevents Acute Doxorubicin Cardiotoxicity by Suppressing Oxidative Stress and Endoplasmic Reticulum-Mediated Apoptosis Marine Drugs. Dec, 2016 | Pubmed ID: 27999379 Opposing Roles of Wnt Inhibitors IGFBP-4 and Dkk1 in Cardiac Ischemia by Differential Targeting of LRP5/6 and β-catenin Circulation. Dec, 2016 | Pubmed ID: 27803037 Non-invasively Differentiating Extent of Liver Fibrosis by Visualizing Hepatic Integrin αvβ3 Expression with an MRI Modality in Mice Biomaterials. 09, 2016 | Pubmed ID: 27341269 Aldehyde Dehydrogenase 2 Deficiency Blunts Compensatory Cardiac Hypertrophy Through Modulating Akt Phosphorylation Early After Transverse Aorta Constriction in Mice Biochimica Et Biophysica Acta. Sep, 2016 | Pubmed ID: 27239698 The Effects of Different Angiotensin II Type 1 Receptor Blockers on the Regulation of the ACE-AngII-AT1 and ACE2-Ang(1-7)-Mas Axes in Pressure Overload-induced Cardiac Remodeling in Male Mice Journal of Molecular and Cellular Cardiology. 08, 2016 | Pubmed ID: 27210827 Utilization of Animal Models to Investigate Nonalcoholic Steatohepatitis-associated Hepatocellular Carcinoma Oncotarget. Jul, 2016 | Pubmed ID: 27072576 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition) Autophagy. Jan, 2016 | Pubmed ID: 26799652 Extracellular High-mobility Group Box 1 Mediates Pressure Overload-induced Cardiac Hypertrophy and Heart Failure Journal of Cellular and Molecular Medicine. Mar, 2016 | Pubmed ID: 26647902 Ovarian Granulocytic Sarcoma As the Primary Manifestation of Acute Myelogenous Leukemia International Journal of Clinical and Experimental Pathology. 2015 | Pubmed ID: 26722572 Inhibition of Autophagy Potentiated the Antitumor Effect of Nedaplatin in Cisplatin-Resistant Nasopharyngeal Carcinoma Cells PloS One. 2015 | Pubmed ID: 26288183 Letter to the Editor: When What You See Might Not Be What You Get: Prudent Considerations of Anesthetics for Murine Echocardiography American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2015 | Pubmed ID: 26078381 Epigenetic Regulation of Hepatic Tumor-initiating Cells Frontiers in Bioscience (Landmark Edition). 06, 2015 | Pubmed ID: 25961535 Protective Effect of the Traditional Chinese Medicine Xuesaitong on Intestinal Ischemia-reperfusion Injury in Rats International Journal of Clinical and Experimental Medicine. 2015 | Pubmed ID: 25932105 Combination Treatment With Antihypertensive Agents Enhances the Effect of Qiliqiangxin on Chronic Pressure Overload-induced Cardiac Hypertrophy and Remodeling in Male Mice Journal of Cardiovascular Pharmacology. Jun, 2015 | Pubmed ID: 25806688 Characterization of Coronary Flow Reserve and Left Ventricular Remodeling in a Mouse Model of Chronic Aortic Regurgitation with Carvedilol Intervention Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Mar, 2015 | Pubmed ID: 25715369 BIRC6 Promotes Hepatocellular Carcinogenesis: Interaction of BIRC6 with P53 Facilitating P53 Degradation International Journal of Cancer. Mar, 2015 | Pubmed ID: 25196217 Synchronous Poorly-differentiated Neuroendocrine Carcinoma and Gastrointestinal Stromal Tumor of the Stomach: a Case Report with Immunohistochemical and Molecular Genetic Analyses of KIT and PDGFRA International Journal of Clinical and Experimental Pathology. 2014 | Pubmed ID: 25674291 Subdomain II of α-isopropylmalate Synthase is Essential for Activity: Inferring a Mechanism of Feedback Inhibition The Journal of Biological Chemistry. Oct, 2014 | Pubmed ID: 25128527 Aliskiren Ameliorates Pressure Overload-induced Heart Hypertrophy and Fibrosis in Mice Acta Pharmacologica Sinica. Aug, 2014 | Pubmed ID: 24998254 Tumor Necrosis Factor-alpha-induced Reduction of Glomerular Filtration Rate in Rats with Fulminant Hepatic Failure Laboratory Investigation; a Journal of Technical Methods and Pathology. Jul, 2014 | Pubmed ID: 24887412 Activation of Farnesoid X Receptor (FXR) Protects Against Fructose-induced Liver Steatosis Via Inflammatory Inhibition and ADRP Reduction Biochemical and Biophysical Research Communications. Jul, 2014 | Pubmed ID: 24875360 Insights into the Activation and Inhibition of Angiotensin II Type 1 Receptor in the Mechanically Loaded Heart Circulation Journal : Official Journal of the Japanese Circulation Society. 2014 | Pubmed ID: 24813328 Src is Required for Mechanical Stretch-induced Cardiomyocyte Hypertrophy Through Angiotensin II Type 1 Receptor-dependent β-arrestin2 Pathways PloS One. 2014 | Pubmed ID: 24699426 A Reusable Evanescent Wave Immunosensor for Highly Sensitive Detection of Bisphenol A in Water Samples Scientific Reports. 2014 | Pubmed ID: 24699239 Urotensin II Inhibited the Proliferation of Cardiac Side Population Cells in Mice During Pressure Overload by JNK-LRP6 Signalling Journal of Cellular and Molecular Medicine. May, 2014 | Pubmed ID: 24447593 Chinese Guidelines for Endovascular Management of Ischemic Cerebrovascular Diseases Interventional Neurology. Sep, 2013 | Pubmed ID: 25187777 Bupleurum Polysaccharides Attenuates Lipopolysaccharide-induced Inflammation Via Modulating Toll-like Receptor 4 Signaling PloS One. 2013 | Pubmed ID: 24167596 Evaluation of Bi-ventricular Coronary Flow Patterns Using High-frequency Ultrasound in Mice with Transverse Aortic Constriction Ultrasound in Medicine & Biology. Nov, 2013 | Pubmed ID: 23932279 Increases in the Risk of Cognitive Impairment and Alterations of Cerebral β-amyloid Metabolism in Mouse Model of Heart Failure PloS One. 2013 | Pubmed ID: 23737953 FSH Enhances the Proliferation of Ovarian Cancer Cells by Activating Transient Receptor Potential Channel C3 Endocrine-related Cancer. Jun, 2013 | Pubmed ID: 23580589 Olmesartan Attenuates Cardiac Remodeling Through DLL4/Notch1 Pathway Activation in Pressure Overload Mice Journal of Cardiovascular Pharmacology. Feb, 2013 | Pubmed ID: 23188126 Comparison Between Adenosine and Isoflurane for Assessing the Coronary Flow Reserve in Mouse Models of Left Ventricular Pressure and Volume Overload American Journal of Physiology. Heart and Circulatory Physiology. Nov, 2012 | Pubmed ID: 23001834 Capturing Circulating Tumor Cells of Hepatocellular Carcinoma Cancer Letters. Dec, 2012 | Pubmed ID: 22842097 SCM-198 Attenuates Early Atherosclerotic Lesions in Hypercholesterolemic Rabbits Via Modulation of the Inflammatory and Oxidative Stress Pathways Atherosclerosis. Sep, 2012 | Pubmed ID: 22840690 Noninvasive Estimation of Infarct Size in a Mouse Model of Myocardial Infarction by Echocardiographic Coronary Perfusion Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Jul, 2012 | Pubmed ID: 22733860 Association of Stat3 with HSF1 Plays a Critical Role in G-CSF-induced Cardio-protection Against Ischemia/reperfusion Injury Journal of Molecular and Cellular Cardiology. Jun, 2012 | Pubmed ID: 22426029 Early Estimation of Left Ventricular Systolic Pressure and Prediction of Successful Aortic Constriction in a Mouse Model of Pressure Overload by Ultrasound Biomicroscopy Ultrasound in Medicine & Biology. Jun, 2012 | Pubmed ID: 22425378 Qiliqiangxin Inhibits the Development of Cardiac Hypertrophy, Remodeling, and Dysfunction During 4 Weeks of Pressure Overload in Mice Journal of Cardiovascular Pharmacology. Mar, 2012 | Pubmed ID: 22075750 Heat Shock Transcription Factor 1 Protects Heart After Pressure Overload Through Promoting Myocardial Angiogenesis in Male Mice Journal of Molecular and Cellular Cardiology. Nov, 2011 | Pubmed ID: 21854784 Molecular Imaging of Hepatic Stellate Cell Activity by Visualization of Hepatic Integrin αvβ3 Expression with SPECT in Rat Hepatology (Baltimore, Md.). Sep, 2011 | Pubmed ID: 21618580 Urotensin II Inhibits the Proliferation but Not the Differentiation of Cardiac Side Population Cells Peptides. May, 2011 | Pubmed ID: 21291940 Effects of Heart Rate and Anesthetic Timing on High-resolution Echocardiographic Assessment Under Isoflurane Anesthesia in Mice Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. Dec, 2010 | Pubmed ID: 21098849 Comparison of Angiotensin II Type 1-receptor Blockers to Regress Pressure Overload-induced Cardiac Hypertrophy in Mice Hypertension Research : Official Journal of the Japanese Society of Hypertension. Dec, 2010 | Pubmed ID: 20944638 Mechanical Stress-evoked but Angiotensin II-independent Activation of Angiotensin II Type 1 Receptor Induces Cardiac Hypertrophy Through Calcineurin Pathway Biochemical and Biophysical Research Communications. Jun, 2010 | Pubmed ID: 20580688 The Location of Invasion-related Protein MIC3 of Toxoplasma Gondii and Protective Effect of Its DNA Vaccine in Mice Veterinary Parasitology. Dec, 2009 | Pubmed ID: 19800170 Improvement of Recipient Survival After Small Size Graft Liver Transplantation in Rats with Preischemic Manipulation or Administering Antisense Against Nuclear Factor-kappaB Transplant International : Official Journal of the European Society for Organ Transplantation. Sep, 2007 | Pubmed ID: 17535306 Cyclic Arg-Gly-Asp Peptide-labeled Liposomes for Targeting Drug Therapy of Hepatic Fibrosis in Rats The Journal of Pharmacology and Experimental Therapeutics. Aug, 2007 | Pubmed ID: 17510318 Effects of Fatty Liver and Related Factors on the Efficacy of Combination Antiviral Therapy in Patients with Chronic Hepatitis C Liver International : Official Journal of the International Association for the Study of the Liver. Mar, 2006 | Pubmed ID: 16448454 Differential Metastasis-associated Gene Analysis of Prostate Carcinoma Cells Derived from Primary Tumor and Spontaneous Lymphatic Metastasis in Nude Mice with Orthotopic Implantation of PC-3M Cells Cancer Letters. Feb, 2006 | Pubmed ID: 15885894 X-ray Crystallography, CD and Kinetic Studies Revealed the Essence of the Abnormal Behaviors of the Cytochrome B5 Phe35-->Tyr Mutant European Journal of Biochemistry. Sep, 2002 | Pubmed ID: 12199707 Surgically Induced Cardiac Volume Overload by Aortic Regurgitation in Mouse Jian Wu*1, Shijun Wang*1, Le Kang*1, Chunjie Yang*1, Jianguo Jia1, Xingxu Wang2, Ge Wei1, Xuan Li1, Jieyun You2, Yunzeng Zou1 1Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, 2Department of Cardiovascular Medicine, Shanghai East Hospital, School of Medicine, Tongji University JoVE 63579 Biologie Tactile Vibrating Toolkit and Driving Simulation Platform for Driving-Related Research Ao Zhu1, Annebella Tsz Ho Choi1, Ko-Hsuan Ma1, Shi Cao2, Han Yao1, Jian Wu3, Jibo He1 1Psychology Department, School of Social Sciences, Tsinghua University, 2Department of Systems Design Engineering, University of Waterloo, 3Haier Innovation Design Center, Haier Company JoVE 61408 Comportement An Assessment Method and Toolkit to Evaluate Keyboard Design on Smartphones Yincheng Wang1, Ke Wang1, Yuqi Huang1, Di Wu2, Jian Wu3, Jibo He1 1Department of Psychology, School of Social Sciences, Tsinghua University, 2Department of Computer Science, Beijing Normal University, 3Haier Innovation Design Center, Haier Company JoVE 61796 Comportement Isolation and Culture of Adult Mouse Cardiomyocytes for Cell Signaling and in vitro Cardiac Hypertrophy Daxiang Li1, Jian Wu1, Yan Bai1, Xiaochen Zhao2, Lijun Liu1 1Department of Biochemistry and Cancer Biology, University of Toledo College of Medicine and Life Sciences, 2Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences JoVE 51357 Biologie
Surgically Induced Cardiac Volume Overload by Aortic Regurgitation in Mouse Jian Wu*1, Shijun Wang*1, Le Kang*1, Chunjie Yang*1, Jianguo Jia1, Xingxu Wang2, Ge Wei1, Xuan Li1, Jieyun You2, Yunzeng Zou1 1Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital and Institutes of Biomedical Sciences, Fudan University, 2Department of Cardiovascular Medicine, Shanghai East Hospital, School of Medicine, Tongji University JoVE 63579 Biologie
Tactile Vibrating Toolkit and Driving Simulation Platform for Driving-Related Research Ao Zhu1, Annebella Tsz Ho Choi1, Ko-Hsuan Ma1, Shi Cao2, Han Yao1, Jian Wu3, Jibo He1 1Psychology Department, School of Social Sciences, Tsinghua University, 2Department of Systems Design Engineering, University of Waterloo, 3Haier Innovation Design Center, Haier Company JoVE 61408 Comportement
An Assessment Method and Toolkit to Evaluate Keyboard Design on Smartphones Yincheng Wang1, Ke Wang1, Yuqi Huang1, Di Wu2, Jian Wu3, Jibo He1 1Department of Psychology, School of Social Sciences, Tsinghua University, 2Department of Computer Science, Beijing Normal University, 3Haier Innovation Design Center, Haier Company JoVE 61796 Comportement
Isolation and Culture of Adult Mouse Cardiomyocytes for Cell Signaling and in vitro Cardiac Hypertrophy Daxiang Li1, Jian Wu1, Yan Bai1, Xiaochen Zhao2, Lijun Liu1 1Department of Biochemistry and Cancer Biology, University of Toledo College of Medicine and Life Sciences, 2Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences JoVE 51357 Biologie