John Rossi Department of Molecular and Cellular Biology Beckman Research Institute of City of Hope Biography Publications Institution JoVE Articles John Rossi has not added a biography. If you are John Rossi and would like to personalize this page please email our Author Liaison for assistance. Publications Screening Effective Target Sites on MRNA: A Ribozyme Library Approach Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22315078 Value-ladenness and Rationality in Health Communication The American Journal of Bioethics : AJOB. Feb, 2012 | Pubmed ID: 22304512 RNA-Based Therapeutics: Current Progress and Future Prospects Chemistry & Biology. Jan, 2012 | Pubmed ID: 22284355 The Development of RNA Interference Therapeutics Nucleic Acid Therapeutics. Dec, 2011 | Pubmed ID: 22196369 Lack of Expression and Function of Erythropoietin Receptors in the Kidney Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. Dec, 2011 | Pubmed ID: 22167585 Interplay Between HIV-1 Infection and Host MicroRNAs Nucleic Acids Research. Nov, 2011 | Pubmed ID: 22080513 A Novel Nuclear MiRNA Mediated Modulation of a Non-coding Antisense RNA and Its Cognate Sense Coding MRNA The EMBO Journal. Nov, 2011 | Pubmed ID: 22048334 A Bias-reducing Strategy in Profiling Small RNAs Using Solexa RNA (New York, N.Y.). Dec, 2011 | Pubmed ID: 22016383 Systemic Administration of Combinatorial DsiRNAs Via Nanoparticles Efficiently Suppresses HIV-1 Infection in Humanized Mice Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2011 | Pubmed ID: 21952167 MicroRNAs and Their Potential Involvement in HIV Infection Trends in Pharmacological Sciences. Nov, 2011 | Pubmed ID: 21862142 Small Interfering RNAs Targeting Cyclin D1 and Cyclin D2 Enhance the Cytotoxicity of Chemotherapeutic Agents in Mantle Cell Lymphoma Cell Lines Leukemia & Lymphoma. Nov, 2011 | Pubmed ID: 21745168 Current Progress of SiRNA/shRNA Therapeutics in Clinical Trials Biotechnology Journal. Sep, 2011 | Pubmed ID: 21744502 Phylogenetic Comparison of Small RNA-triggered Transcriptional Gene Silencing The Journal of Biological Chemistry. Aug, 2011 | Pubmed ID: 21730056 A Critical Role for SHP2 in STAT5 Activation and Growth Factor-mediated Proliferation, Survival, and Differentiation of Human CD34+ Cells Blood. Aug, 2011 | Pubmed ID: 21670473 A Boost for the Emerging Field of RNA Nanotechnology ACS Nano. May, 2011 | Pubmed ID: 21604810 Human Brain EEG Indices of Emotions: Delineating Responses to Affective Vocalizations by Measuring Frontal Theta Event-related Synchronization Neuroscience and Biobehavioral Reviews. Oct, 2011 | Pubmed ID: 21596060 Thermodynamic Stability of Small Hairpin RNAs Highly Influences the Loading Process of Different Mammalian Argonautes Proceedings of the National Academy of Sciences of the United States of America. May, 2011 | Pubmed ID: 21576459 Ex Vivo Gene Therapy for HIV-1 Treatment Human Molecular Genetics. Apr, 2011 | Pubmed ID: 21505069 Stopping RNA Interference at the Seed Nature Genetics. Apr, 2011 | Pubmed ID: 21445071 Aptamer-targeted RNAi for HIV-1 Therapy Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21431697 Progress in RNAi-based Antiviral Therapeutics Methods in Molecular Biology (Clifton, N.J.). 2011 | Pubmed ID: 21431679 RNA Nanoparticles Come of Age Acta Biochimica Et Biophysica Sinica. Apr, 2011 | Pubmed ID: 21430091 Inducible and Reversible Breaching of the Blood Brain Barrier by RNAi EMBO Molecular Medicine. Apr, 2011 | Pubmed ID: 21394916 Dual Functional RNA Nanoparticles Containing Phi29 Motor PRNA and Anti-gp120 Aptamer for Cell-type Specific Delivery and HIV-1 Inhibition Methods (San Diego, Calif.). Jun, 2011 | Pubmed ID: 21256218 An Aptamer-siRNA Chimera Suppresses HIV-1 Viral Loads and Protects from Helper CD4(+) T Cell Decline in Humanized Mice Science Translational Medicine. Jan, 2011 | Pubmed ID: 21248316 OTS Highlights Advance in Basic and Translational Aspects of Oligonucleotide Research Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2011 | Pubmed ID: 21200390 Cell-specific Aptamer-mediated Targeted Drug Delivery Oligonucleotides. Feb, 2011 | Pubmed ID: 21182455 A Role for Human Dicer in Pre-RISC Loading of SiRNAs Nucleic Acids Research. Mar, 2011 | Pubmed ID: 20972213 Population Pharmacokinetic/pharmacodynamic Model of Subcutaneous Adipose 11β-hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Activity After Oral Administration of AMG 221, a Selective 11β-HSD1 Inhibitor Journal of Clinical Pharmacology. Jun, 2011 | Pubmed ID: 20663992 Biogenesis and Function of Endogenous and Exogenous SiRNAs Wiley Interdisciplinary Reviews. RNA. Jul, 2010 | Pubmed ID: 21956909 Is Equal Moral Consideration Really Compatible with Unequal Moral Status? Kennedy Institute of Ethics Journal. Sep, 2010 | Pubmed ID: 21133335 RNAi and Small Interfering RNAs in Human Disease Therapeutic Applications Trends in Biotechnology. Nov, 2010 | Pubmed ID: 20833440 Survival of the Fittest: Positive Selection of CD4+ T Cells Expressing a Membrane-bound Fusion Inhibitor Following HIV-1 Infection PloS One. 2010 | Pubmed ID: 20808813 Post-transcriptional Up-regulation of Tsc-22 by Ybx1, a Target of MiR-216a, Mediates TGF-{beta}-induced Collagen Expression in Kidney Cells The Journal of Biological Chemistry. Oct, 2010 | Pubmed ID: 20713358 RNA-based Gene Therapy for HIV with Lentiviral Vector-modified CD34(+) Cells in Patients Undergoing Transplantation for AIDS-related Lymphoma Science Translational Medicine. Jun, 2010 | Pubmed ID: 20555022 International Research and Positive Obligations: Are They "transaction Specific"? The American Journal of Bioethics : AJOB. Jun, 2010 | Pubmed ID: 20526974 Silencing of Gene Expression in Cultured Cells Using Small Interfering RNAs Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [et Al.]. Jun, 2010 | Pubmed ID: 20521232 Dual-targeting SiRNAs RNA (New York, N.Y.). Jun, 2010 | Pubmed ID: 20410240 Combinatorial Latency Reactivation for HIV-1 Subtypes and Variants Journal of Virology. Jun, 2010 | Pubmed ID: 20357084 Aptamer-targeted Cell-specific RNA Interference Silence. 2010 | Pubmed ID: 20226078 Strategies in Designing Multigene Expression Units to Downregulate HIV-1 Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20217548 A Dual Function TAR Decoy Serves As an Anti-HIV SiRNA Delivery Vehicle Virology Journal. 2010 | Pubmed ID: 20144240 Absence of Functional EpoR Expression in Human Tumor Cell Lines Blood. May, 2010 | Pubmed ID: 20124514 Rational Design of Micro-RNA-like Bifunctional SiRNAs Targeting HIV and the HIV Coreceptor CCR5 Molecular Therapy : the Journal of the American Society of Gene Therapy. Apr, 2010 | Pubmed ID: 20104214 Identification of a Sensitive Anti-erythropoietin Receptor Monoclonal Antibody Allows Detection of Low Levels of EpoR in Cells Journal of Immunological Methods. Jan, 2010 | Pubmed ID: 19887071 Sequence Context Outside the Target Region Influences the Effectiveness of MiR-223 Target Sites in the RhoB 3'UTR Nucleic Acids Research. Jan, 2010 | Pubmed ID: 19850724 RNAi-based Therapeutics-current Status, Challenges and Prospects EMBO Molecular Medicine. Jun, 2009 | Pubmed ID: 20049714 CRM1 Mediates Nuclear-cytoplasmic Shuttling of Mature MicroRNAs Proceedings of the National Academy of Sciences of the United States of America. Dec, 2009 | Pubmed ID: 19955415 Protection of Stem Cell-derived Lymphocytes in a Primate AIDS Gene Therapy Model After in Vivo Selection PloS One. 2009 | Pubmed ID: 19888329 The Therapeutic Potential of Cell-internalizing Aptamers Current Topics in Medicinal Chemistry. 2009 | Pubmed ID: 19860714 Effect of Saphenous Vein Diameter on Closure Rate with ClosureFAST Radiofrequency Catheter Vascular and Endovascular Surgery. Dec, 2009 | Pubmed ID: 19828586 In Vivo Delivery of SiRNA to Immune Cells by Conjugation to a TLR9 Agonist Enhances Antitumor Immune Responses Nature Biotechnology. Oct, 2009 | Pubmed ID: 19749770 A Risk Variant in an MiR-125b Binding Site in BMPR1B is Associated with Breast Cancer Pathogenesis Cancer Research. Sep, 2009 | Pubmed ID: 19738052 Problems Associated with Reporter Assays in RNAi Studies RNA Biology. Sep-Oct, 2009 | Pubmed ID: 19617709 SNPs in Human MiRNA Genes Affect Biogenesis and Function RNA (New York, N.Y.). Sep, 2009 | Pubmed ID: 19617315 Evidence for X-chromosomal Schizophrenia Associated with MicroRNA Alterations PloS One. 2009 | Pubmed ID: 19568434 TGF-beta Activates Akt Kinase Through a MicroRNA-dependent Amplifying Circuit Targeting PTEN Nature Cell Biology. Jul, 2009 | Pubmed ID: 19543271 New Hope for a MicroRNA Therapy for Liver Cancer Cell. Jun, 2009 | Pubmed ID: 19524500 Transcriptional Gene Silencing Using Small RNAs Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19495692 Dotting the I's and Crossing the T's: Integration Analyses in Transduced Patient T Cells Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2009 | Pubmed ID: 19404325 Nonhuman Primate Research: the Wrong Way to Understand Needs and Necessity The American Journal of Bioethics : AJOB. May, 2009 | Pubmed ID: 19396676 Overview of Gene Silencing by RNA Interference Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [et Al.]. Mar, 2009 | Pubmed ID: 19319858 Selection, Characterization and Application of New RNA HIV Gp 120 Aptamers for Facile Delivery of Dicer Substrate SiRNAs into HIV Infected Cells Nucleic Acids Research. May, 2009 | Pubmed ID: 19304999 The Promises and Pitfalls of RNA-interference-based Therapeutics Nature. Jan, 2009 | Pubmed ID: 19158789 Designing and Utilization of SiRNAs Targeting RNA Binding Proteins Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18982303 A Role for the Dicer Helicase Domain in the Processing of Thermodynamically Unstable Hairpin RNAs Nucleic Acids Research. Nov, 2008 | Pubmed ID: 18927112 MicroRNA-directed Transcriptional Gene Silencing in Mammalian Cells Proceedings of the National Academy of Sciences of the United States of America. Oct, 2008 | Pubmed ID: 18852463 Toward a Zoocentric Animal Ethics The American Journal of Bioethics : AJOB. Jun, 2008 | Pubmed ID: 18726783 Functional and Intracellular Localization Properties of U6 Promoter-expressed SiRNAs, ShRNAs, and Chimeric VA1 ShRNAs in Mammalian Cells RNA (New York, N.Y.). Sep, 2008 | Pubmed ID: 18697923 Lentiviral Vector Delivery of SiRNA and ShRNA Encoding Genes into Cultured and Primary Hematopoietic Cells Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18679631 Chemical Modification Patterns Compatible with High Potency Dicer-substrate Small Interfering RNAs Oligonucleotides. Jun, 2008 | Pubmed ID: 18637735 Bivalent Aptamers Deliver the Punch Chemistry & Biology. Jul, 2008 | Pubmed ID: 18635000 Wandering Eye for RNAi Nature Medicine. Jun, 2008 | Pubmed ID: 18535575 RNAi Mechanisms and Applications BioTechniques. Apr, 2008 | Pubmed ID: 18474035 Novel Dual Inhibitory Function Aptamer-siRNA Delivery System for HIV-1 Therapy Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2008 | Pubmed ID: 18461053 Realizing the Promise of RNAi Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2008 | Pubmed ID: 18432272 Tat-regulated Expression of RNA Interference: Triggers for the Treatment of HIV Infection Current HIV/AIDS Reports. Feb, 2008 | Pubmed ID: 18417034 Use of a U16 SnoRNA-containing Ribozyme Library to Identify Ribozyme Targets in HIV-1 Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2008 | Pubmed ID: 18388915 Principles of Dicer Substrate (D-siRNA) Design and Function Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18369774 Expression Strategies for Short Hairpin RNA Interference Triggers Human Gene Therapy. Apr, 2008 | Pubmed ID: 18363506 Expression of Long Anti-HIV-1 Hairpin RNAs for the Generation of Multiple SiRNAs: Advantages and Limitations Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2008 | Pubmed ID: 17726454 Lentivirus Transduction of Hematopoietic Cells CSH Protocols. 2007 | Pubmed ID: 21357086 Genetic Therapies Against HIV Nature Biotechnology. Dec, 2007 | Pubmed ID: 18066041 MicroRNAs in Disease and Potential Therapeutic Applications Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2007 | Pubmed ID: 17878899 Targeted Cleavage: Tuneable Cis-cleaving Ribozymes Proceedings of the National Academy of Sciences of the United States of America. Sep, 2007 | Pubmed ID: 17855561 Cloning and Detecting Signature MicroRNAs from Mammalian Cells Methods in Enzymology. 2007 | Pubmed ID: 17720482 Combinatorial Delivery of Small Interfering RNAs Reduces RNAi Efficacy by Selective Incorporation into RISC Nucleic Acids Research. 2007 | Pubmed ID: 17660190 Molecular Medicine: Entry Granted Nature. Jul, 2007 | Pubmed ID: 17611531 Short Hairpin RNA Causes the Methylation of Transforming Growth Factor-beta Receptor II Promoter and Silencing of the Target Gene in Rat Hepatic Stellate Cells Biochemical and Biophysical Research Communications. Jul, 2007 | Pubmed ID: 17533113 RNAi Therapeutics: Principles, Prospects and Challenges Advanced Drug Delivery Reviews. Mar, 2007 | Pubmed ID: 17449137 Optimization and Characterization of TRNA-shRNA Expression Constructs Nucleic Acids Research. 2007 | Pubmed ID: 17426139 Epigenetics and MicroRNAs Pediatric Research. May, 2007 | Pubmed ID: 17413846 Safety and Efficacy of a Lentiviral Vector Containing Three Anti-HIV Genes--CCR5 Ribozyme, Tat-rev SiRNA, and TAR Decoy--in SCID-hu Mouse-derived T Cells Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2007 | Pubmed ID: 17406343 Potent SiRNA Inhibitors of Ribonucleotide Reductase Subunit RRM2 Reduce Cell Proliferation in Vitro and in Vivo Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2007 | Pubmed ID: 17404105 Distance Constraints Between MicroRNA Target Sites Dictate Efficacy and Cooperativity Nucleic Acids Research. 2007 | Pubmed ID: 17389647 MicroRNA-192 in Diabetic Kidney Glomeruli and Its Function in TGF-beta-induced Collagen Expression Via Inhibition of E-box Repressors Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007 | Pubmed ID: 17360662 Cross-clade Inhibition of Recombinant Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus SIVcpz Reverse Transcriptases by RNA Pseudoknot Aptamers Journal of Virology. May, 2007 | Pubmed ID: 17329328 A Facile Lentiviral Vector System for Expression of Doxycycline-inducible ShRNAs: Knockdown of the Pre-miRNA Processing Enzyme Drosha Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2007 | Pubmed ID: 17311008 Strategies for Silencing Human Disease Using RNA Interference Nature Reviews. Genetics. Mar, 2007 | Pubmed ID: 17304245 Transcriptional Activation by Small RNA Duplexes Nature Chemical Biology. Mar, 2007 | Pubmed ID: 17301798 Metalloproteases Regulate T-cell Proliferation and Effector Function Via LAG-3 The EMBO Journal. Jan, 2007 | Pubmed ID: 17245433 Rational Design and in Vitro and in Vivo Delivery of Dicer Substrate SiRNA Nature Protocols. 2006 | Pubmed ID: 17406276 Endogenous Expression of an Anti-TAR Aptamer Reduces HIV-1 Replication RNA Biology. Oct, 2006 | Pubmed ID: 17299271 Chemical Modifications Rescue Off-target Effects of RNAi ACS Chemical Biology. Jun, 2006 | Pubmed ID: 17163754 Inhibition of Infectious Human Immunodeficiency Virus Type 1 Virions Via Lentiviral Vector Encoded Short Antisense RNAs Oligonucleotides. 2006 | Pubmed ID: 17155905 RNAi in Combination with a Ribozyme and TAR Decoy for Treatment of HIV Infection in Hematopoietic Cell Gene Therapy Annals of the New York Academy of Sciences. Oct, 2006 | Pubmed ID: 17145937 Small Interfering RNAs to the Rescue: Blocking L1 Retrotransposition Nature Structural & Molecular Biology. Sep, 2006 | Pubmed ID: 16955095 Interaction of Muscleblind, CUG-BP1 and HnRNP H Proteins in DM1-associated Aberrant IR Splicing The EMBO Journal. Sep, 2006 | Pubmed ID: 16946708 Toxicity in Mice Expressing Short Hairpin RNAs Gives New Insight into RNAi Genome Biology. 2006 | Pubmed ID: 16942630 Argonaute-1 Directs SiRNA-mediated Transcriptional Gene Silencing in Human Cells Nature Structural & Molecular Biology. Sep, 2006 | Pubmed ID: 16936726 Expressing Short Hairpin RNAs in Vivo Nature Methods. Sep, 2006 | Pubmed ID: 16929313 Partnering Aptamer and RNAi Technologies Molecular Therapy : the Journal of the American Society of Gene Therapy. Oct, 2006 | Pubmed ID: 16920031 Bcl-2 Protein in 518A2 Melanoma Cells in Vivo and in Vitro Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Aug, 2006 | Pubmed ID: 16914583 Lentivirus-mediated RNA Interference Therapy for Human Immunodeficiency Virus Type 1 Infection Human Gene Therapy. May, 2006 | Pubmed ID: 16716105 A Nucleolar Localizing Rev Binding Element Inhibits HIV Replication AIDS Research and Therapy. 2006 | Pubmed ID: 16712721 Stable Expression of ShRNAs in Human CD34+ Progenitor Cells Can Avoid Induction of Interferon Responses to SiRNAs in Vitro Nature Biotechnology. May, 2006 | Pubmed ID: 16648841 RNAi As a Treatment for HIV-1 Infection BioTechniques. Apr, 2006 | Pubmed ID: 16629384 The Diversity of RNAi and Its Applications BioTechniques. Apr, 2006 | Pubmed ID: 16629381 Antiviral Applications of RNAi Current Opinion in Molecular Therapeutics. Apr, 2006 | Pubmed ID: 16610763 Novel Pol II Fusion Promoter Directs Human Immunodeficiency Virus Type 1-inducible Coexpression of a Short Hairpin RNA and Protein Journal of Virology. Feb, 2006 | Pubmed ID: 16439542 The Antisense Strand of Small Interfering RNAs Directs Histone Methylation and Transcriptional Gene Silencing in Human Cells RNA (New York, N.Y.). Feb, 2006 | Pubmed ID: 16373483 Enhancing SiRNA Effects in T Cells for Adoptive Immunotherapy Hematology (Amsterdam, Netherlands). Dec, 2005 | Pubmed ID: 16321811 Mammalian Dicer Finds a Partner EMBO Reports. Oct, 2005 | Pubmed ID: 16222240 Approaches for Chemically Synthesized SiRNA and Vector-mediated RNAi FEBS Letters. Oct, 2005 | Pubmed ID: 16199038 Long-term Inhibition of HIV-1 Infection in Primary Hematopoietic Cells by Lentiviral Vector Delivery of a Triple Combination of Anti-HIV ShRNA, Anti-CCR5 Ribozyme, and a Nucleolar-localizing TAR Decoy Molecular Therapy : the Journal of the American Society of Gene Therapy. Nov, 2005 | Pubmed ID: 16115802 Functional Polarity is Introduced by Dicer Processing of Short Substrate RNAs Nucleic Acids Research. 2005 | Pubmed ID: 16049023 HnRNP H Inhibits Nuclear Export of MRNA Containing Expanded CUG Repeats and a Distal Branch Point Sequence Nucleic Acids Research. 2005 | Pubmed ID: 16027111 RNAi and the P-body Connection Nature Cell Biology. Jul, 2005 | Pubmed ID: 15990892 Lentiviral Vector Delivery of SiRNA and ShRNA Encoding Genes into Cultured and Primary Hematopoietic Cells Methods in Molecular Biology (Clifton, N.J.). 2005 | Pubmed ID: 15990406 A Society of Our Own Oligonucleotides. 2005 | Pubmed ID: 15989421 Martin Tabler, Ph.D. June 20, 1956-April 3, 2005 Oligonucleotides. 2005 | Pubmed ID: 15989420 Short Hairpin RNA-directed Cytosine (CpG) Methylation of the RASSF1A Gene Promoter in HeLa Cells Molecular Therapy : the Journal of the American Society of Gene Therapy. Jul, 2005 | Pubmed ID: 15963934 Receptor-targeted SiRNAs Nature Biotechnology. Jun, 2005 | Pubmed ID: 15940237 Behavioral Test Methods Workshop Neurotoxicology and Teratology. May-Jun, 2005 | Pubmed ID: 15939202 Current Status of Gene Therapy Strategies to Treat HIV/AIDS Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2005 | Pubmed ID: 15922953 Small Nuclear RNAs Encoded by Herpesvirus Saimiri Upregulate the Expression of Genes Linked to T Cell Activation in Virally Transformed T Cells Current Biology : CB. May, 2005 | Pubmed ID: 15916956 Amplification of RNAi--targeting HLA MRNAs Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2005 | Pubmed ID: 15851019 Helping RNAi Deliver Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2005 | Pubmed ID: 15851004 Ribozyme Cleavage Leads to Decreased Expression of Fibroblast Growth Factor Receptor 3 in Human Multiple Myeloma Cells, Which is Associated with Apoptosis and Downregulation of Vascular Endothelial Growth Factor Oligonucleotides. 2005 | Pubmed ID: 15788896 Comparative Single-turnover Kinetic Analyses of Trans-cleaving Hammerhead Ribozymes with Naturally Derived Non-conserved Sequence Motifs FEBS Letters. Mar, 2005 | Pubmed ID: 15757651 Sensing the Danger in RNA Nature Medicine. Mar, 2005 | Pubmed ID: 15746933 SiRNA Target Site Secondary Structure Predictions Using Local Stable Substructures Nucleic Acids Research. 2005 | Pubmed ID: 15722476 Cytoplasmic and Nuclear Retained DMPK MRNAs Are Targets for RNA Interference in Myotonic Dystrophy Cells The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15722335 Importance of Public Engagement Found Through Involvement in Horse Slaughter Bill Journal of the American Veterinary Medical Association. Feb, 2005 | Pubmed ID: 15702679 A Potential Role for RNA Interference in Controlling the Activity of the Human LINE-1 Retrotransposon Nucleic Acids Research. 2005 | Pubmed ID: 15701756 Lentiviral Vector Delivery of Recombinant Small Interfering RNA Expression Cassettes Methods in Enzymology. 2005 | Pubmed ID: 15644184 Synthetic DsRNA Dicer Substrates Enhance RNAi Potency and Efficacy Nature Biotechnology. Feb, 2005 | Pubmed ID: 15619617 Uncoupling of RNAi from Active Translation in Mammalian Cells RNA (New York, N.Y.). Jan, 2005 | Pubmed ID: 15574516 Lentiviral Transduction of Tar Decoy and CCR5 Ribozyme into CD34+ Progenitor Cells and Derivation of HIV-1 Resistant T Cells and Macrophages AIDS Research and Therapy. Dec, 2004 | Pubmed ID: 15813986 Negative Feedback Inhibition of HIV-1 by TAT-inducible Expression of SiRNA Nature Biotechnology. Dec, 2004 | Pubmed ID: 15568018 Medicine: a Cholesterol Connection in RNAi Nature. Nov, 2004 | Pubmed ID: 15538347 Therapeutic Applications of RNA Interference: Recent Advances in SiRNA Design Advances in Genetics. 2004 | Pubmed ID: 15522731 Unlocking the Potential of the Human Genome with RNA Interference Nature. Sep, 2004 | Pubmed ID: 15372045 Rapid Assessment of Anti-HIV SiRNA Efficacy Using PCR-derived Pol III ShRNA Cassettes Molecular Therapy : the Journal of the American Society of Gene Therapy. Sep, 2004 | Pubmed ID: 15336659 Recent Applications of RNAi in Mammalian Systems Current Pharmaceutical Biotechnology. Aug, 2004 | Pubmed ID: 15320766 Ribozyme Diagnostics Comes of Age Chemistry & Biology. Jul, 2004 | Pubmed ID: 15271347 Antisense-mediated Inhibition of Human Immunodeficiency Virus (HIV) Replication by Use of an HIV Type 1-based Vector Results in Severely Attenuated Mutants Incapable of Developing Resistance Journal of Virology. Jul, 2004 | Pubmed ID: 15194784 Gene Expression Profiles in the Rat Central Nervous System Induced by JP-8 Jet Fuel Vapor Exposure Neuroscience Letters. Jun, 2004 | Pubmed ID: 15182950 RNAi Applications in Mammalian Cells BioTechniques. Apr, 2004 | Pubmed ID: 15088371 Regulation of Monocyte Chemoattractant Protein-1 by the Oxidized Lipid, 13-hydroperoxyoctadecadienoic Acid, in Vascular Smooth Muscle Cells Via Nuclear Factor-kappa B (NF-kappa B) Journal of Molecular and Cellular Cardiology. Apr, 2004 | Pubmed ID: 15081318 Anti-HIV-1 Gene Expressing Lentiviral Vectors As an Adjunctive Therapy for HIV-1 Infection Current HIV Research. Apr, 2004 | Pubmed ID: 15078182 Control of HIV-1 Replication by RNA Interference Virus Research. Jun, 2004 | Pubmed ID: 15068880 Cyclophilin A is Required for Retinoic Acid-induced Neuronal Differentiation in P19 Cells The Journal of Biological Chemistry. Jun, 2004 | Pubmed ID: 15047706 Construction and Transfection of PCR Products Expressing SiRNAs or ShRNAs in Mammalian Cells Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 15017076 In Vivo Detection of Ribozyme Cleavage Products and RNA Structure by Use of Terminal Transferase-dependent PCR Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 15017045 Interferon Induction by SiRNAs and SsRNAs Synthesized by Phage Polymerase Nature Biotechnology. Mar, 2004 | Pubmed ID: 14990954 Specific Killing of Ph+ Chronic Myeloid Leukemia Cells by a Lentiviral Vector-delivered Anti-bcr/abl Small Hairpin RNA Oligonucleotides. 2003 | Pubmed ID: 15000831 RNA-mediated Inhibition of HIV in a Gene Therapy Setting Annals of the New York Academy of Sciences. Dec, 2003 | Pubmed ID: 14751823 Approaches for the Sequence-specific Knockdown of MRNA Nature Biotechnology. Dec, 2003 | Pubmed ID: 14647331 Coupling of RNAi-mediated Target Downregulation with Gene Replacement Antisense & Nucleic Acid Drug Development. 2003 | Pubmed ID: 12954115 Treatment of Spontaneous and Chemically Induced EEG Paroxysms in the Fischer-344 Rat with Traditional Antiepileptic Drugs or AED+CGP 35348 Polytherapy Progress in Neuro-psychopharmacology & Biological Psychiatry. Aug, 2003 | Pubmed ID: 12921919 Inhibition of HIV-1 Infection by Lentiviral Vectors Expressing Pol III-promoted Anti-HIV RNAs Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2003 | Pubmed ID: 12907142 SiRNAs, Ribozymes and RNA Decoys in Modeling Stem Cell-based Gene Therapy for HIV/AIDS Anticancer Research. May-Jun, 2003 | Pubmed ID: 12894572 Inhibition of HIV-1 by Lentiviral Vector-transduced SiRNAs in T Lymphocytes Differentiated in SCID-hu Mice and CD34+ Progenitor Cell-derived Macrophages Molecular Therapy : the Journal of the American Society of Gene Therapy. Jul, 2003 | Pubmed ID: 12842429 Small Interfering RNAs Expressed from a Pol III Promoter Suppress the EWS/Fli-1 Transcript in an Ewing Sarcoma Cell Line Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2003 | Pubmed ID: 12788655 Biological and Health Effects of Exposure to Kerosene-based Jet Fuels and Performance Additives Journal of Toxicology and Environmental Health. Part B, Critical Reviews. Jul-Aug, 2003 | Pubmed ID: 12775519 Hammerhead Ribozyme-mediated Destruction of Nuclear Foci in Myotonic Dystrophy Myoblasts Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2003 | Pubmed ID: 12718910 Localized Expression of Small RNA Inhibitors in Human Cells Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2003 | Pubmed ID: 12597912 RNA-based Anti-HIV-1 Gene Therapeutic Constructs in SCID-hu Mouse Model Molecular Therapy : the Journal of the American Society of Gene Therapy. Dec, 2002 | Pubmed ID: 12498773 Functional SiRNA Expression from Transfected PCR Products RNA (New York, N.Y.). Nov, 2002 | Pubmed ID: 12458798 Exposure Assessment and the Health of Deployed Forces Drug and Chemical Toxicology. Nov, 2002 | Pubmed ID: 12378949 Enhanced Expression and HIV-1 Inhibition of Chimeric TRNA(Lys3)-ribozymes Under Dual U6 SnRNA and TRNA Promoters Molecular Therapy : the Journal of the American Society of Gene Therapy. Oct, 2002 | Pubmed ID: 12377189 A Nucleolar TAR Decoy Inhibitor of HIV-1 Replication Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002 | Pubmed ID: 12376617 Interaction of MAPK and 12-lipoxygenase Pathways in Growth and Matrix Protein Expression in Mesangial Cells American Journal of Physiology. Renal Physiology. Nov, 2002 | Pubmed ID: 12372774 Alteration of Branch Site Consensus Sequence and Enhanced Pre-mRNA Splicing of an NMDAR1 Intron Not Associated with Schizophrenia American Journal of Medical Genetics. Aug, 2002 | Pubmed ID: 12210277 Durability of Transgene Expression and Vector Integration: Recombinant SV40-derived Gene Therapy Vectors Molecular Therapy : the Journal of the American Society of Gene Therapy. Aug, 2002 | Pubmed ID: 12161189 Expression of Small Interfering RNAs Targeted Against HIV-1 Rev Transcripts in Human Cells Nature Biotechnology. May, 2002 | Pubmed ID: 11981565 Развитие сотового типа конкретных анти-ВИЧ gp120 аптамеры для доставки миРНК Jiehua Zhou1, Haitang Li1, Jane Zhang2, Swiderski Piotr3, John Rossi1 1Department of Molecular and Cellular Biology, Beckman Research Institute of City of Hope, 2Graduate School of Biological Sciences, Beckman Research Institute of City of Hope, 3Shared Resource-DNA/RNA Peptide, Beckman Research Institute of City of Hope JoVE 2954 Immunologie et Infection
Развитие сотового типа конкретных анти-ВИЧ gp120 аптамеры для доставки миРНК Jiehua Zhou1, Haitang Li1, Jane Zhang2, Swiderski Piotr3, John Rossi1 1Department of Molecular and Cellular Biology, Beckman Research Institute of City of Hope, 2Graduate School of Biological Sciences, Beckman Research Institute of City of Hope, 3Shared Resource-DNA/RNA Peptide, Beckman Research Institute of City of Hope JoVE 2954 Immunologie et Infection