José-Alain Sahel Department of Genetics - Sorbonne Université, INSERM, CNRS Institut de la Vision Biography Publications Institution JoVE Articles José-Alain Sahel has not added a biography. If you are José-Alain Sahel and would like to personalize this page please email our Author Liaison for assistance. Publications Restoration of MGluR6 Localization Following AAV-Mediated Delivery in a Mouse Model of Congenital Stationary Night Blindness Investigative Ophthalmology & Visual Science. Mar, 2021 | Pubmed ID: 33729473 Reproducing Diabetic Retinopathy Features Using Newly Developed Human Induced-pluripotent Stem Cell-derived Retinal Müller Glial Cells Glia. Mar, 2021 | Pubmed ID: 33683746 βA1-crystallin Regulates Glucose Metabolism and Mitochondrial Function in Mouse Retinal Astrocytes by Modulating PTP1B Activity Communications Biology. Feb, 2021 | Pubmed ID: 33627831 Safety of Intravitreal Gene Therapy for Treatment of Subjects with Leber Hereditary Optic Neuropathy Due to Mutations in the Mitochondrial ND4 Gene: The REVEAL Study BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. Mar, 2021 | Pubmed ID: 33566264 Near-infrared Fundus Autofluorescence Alterations Correlate with Swept-source Optical Coherence Tomography Angiography Findings in Patients with Retinitis Pigmentosa Scientific Reports. Feb, 2021 | Pubmed ID: 33542393 CHM Mutation Spectrum and Disease: An Update at the Time of Human Therapeutic Trials Human Mutation. Feb, 2021 | Pubmed ID: 33538369 Retinal Phenotype of Patients With Isolated Retinal Degeneration Due to CLN3 Pathogenic Variants in a French Retinitis Pigmentosa Cohort JAMA Ophthalmology. Mar, 2021 | Pubmed ID: 33507216 Optogenetic Therapy: High Spatiotemporal Resolution and Pattern Discrimination Compatible with Vision Restoration in Non-human Primates Communications Biology. Jan, 2021 | Pubmed ID: 33504896 A Splice Variant in Gene Leads to Lactate Transport Deficit in Human IPS Cell-Derived Retinal Pigment Epithelial Cells Cells. Jan, 2021 | Pubmed ID: 33477551 Efficacy and Safety of Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy Treated Within 6 Months of Disease Onset Ophthalmology. Jan, 2021 | Pubmed ID: 33451738 BNIP3L-mediated Mitophagy is Required for Mitochondrial Remodeling During the Differentiation of Optic Nerve Oligodendrocytes Autophagy. Jan, 2021 | Pubmed ID: 33404293 WDR34, a Candidate Gene for Non-syndromic Rod-cone Dystrophy Clinical Genetics. Feb, 2021 | Pubmed ID: 33124039 Quality of Evidence in Ophthalmology: An Overview of Cochrane Reviews Ophthalmology. Feb, 2021 | Pubmed ID: 32652204 Improved Performance and Safety from Argus II Retinal Prosthesis Post-approval Study in France Acta Ophthalmologica. Dec, 2020 | Pubmed ID: 33354943 Bilateral Visual Improvement with Unilateral Gene Therapy Injection for Leber Hereditary Optic Neuropathy Science Translational Medicine. 12, 2020 | Pubmed ID: 33298565 Insulin Inhibits Inflammation-induced Cone Death in Retinal Detachment Journal of Neuroinflammation. Nov, 2020 | Pubmed ID: 33243251 Generation of a Transplantable Population of Human IPSC-Derived Retinal Ganglion Cells Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 33195235 [Vision Restoration: Science Fiction or Reality?] Medecine Sciences : M/S. Nov, 2020 | Pubmed ID: 33151850 Topical Treatment with a Mu Opioid Receptor Agonist Alleviates Corneal Allodynia and Corneal Nerve Sensitization in Mice Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Dec, 2020 | Pubmed ID: 33035833 [On the Inflammatory Origins of AMD] Medecine Sciences : M/S. Oct, 2020 | Pubmed ID: 33026331 Dynamic Full-field Optical Coherence Tomography: 3D Live-imaging of Retinal Organoids Light, Science & Applications. 2020 | Pubmed ID: 32864115 Phototoxic Damage to Cone Photoreceptors Can Be Independent of the Visual Pigment: the Porphyrin Hypothesis Cell Death & Disease. 08, 2020 | Pubmed ID: 32862199 DEEP-PHENOTYPING AND FURTHER INSIGHTS IN ITM2B-RELATED RETINAL DYSTROPHY Retina (Philadelphia, Pa.). Aug, 2020 | Pubmed ID: 32826790 The 10q26 Risk Haplotype of Age-Related Macular Degeneration Aggravates Subretinal Inflammation by Impairing Monocyte Elimination Immunity. Aug, 2020 | Pubmed ID: 32814029 VEGF is an Autocrine/paracrine Neuroprotective Factor for Injured Retinal Ganglion Neurons Scientific Reports. 07, 2020 | Pubmed ID: 32710087 Towards Optogenetic Vision Restoration with High Resolution PLoS Computational Biology. 07, 2020 | Pubmed ID: 32667921 AAV-Mediated Gene Delivery to Foveal Cones Methods in Molecular Biology (Clifton, N.J.). 2020 | Pubmed ID: 32651912 Correlations Between Subjective Evaluation of Quality of Life, Visual Field Loss, and Performance in Simulated Activities of Daily Living in Glaucoma Patients Journal of Glaucoma. 10, 2020 | Pubmed ID: 32649451 Functional Ultrasound Imaging of Deep Visual Cortex in Awake Nonhuman Primates Proceedings of the National Academy of Sciences of the United States of America. 06, 2020 | Pubmed ID: 32513717 Loss of Function of RIMS2 Causes a Syndromic Congenital Cone-Rod Synaptic Disease with Neurodevelopmental and Pancreatic Involvement American Journal of Human Genetics. 06, 2020 | Pubmed ID: 32470375 Baseline Visual Field Findings in the RUSH2A Study: Associated Factors and Correlation With Other Measures of Disease Severity American Journal of Ophthalmology. 11, 2020 | Pubmed ID: 32446738 Impact of the COVID-19 Lockdown on Basic Science Research in Ophthalmology: the Experience of a Highly Specialized Research Facility in France Eye (London, England). Jul, 2020 | Pubmed ID: 32382143 Identification and Characterization of Novel TRPM1 Autoantibodies from Serum of Patients with Melanoma-associated Retinopathy PloS One. 2020 | Pubmed ID: 32324760 Systemic Administration of the Di-apocarotenoid Norbixin (BIO201) is Neuroprotective, Preserves Photoreceptor Function and Inhibits A2E and Lipofuscin Accumulation in Animal Models of Age-related Macular Degeneration and Stargardt Disease Aging. 04, 2020 | Pubmed ID: 32255762 Metabolic and Redox Signaling of the Nucleoredoxin-Like-1 Gene for the Treatment of Genetic Retinal Diseases International Journal of Molecular Sciences. Feb, 2020 | Pubmed ID: 32120883 Progressive Chorioretinal Involvement in a Patient with Light-chain (AL) Amyloidosis: a Case Report BMC Ophthalmology. Feb, 2020 | Pubmed ID: 32085748 AAV-Mediated Gene Delivery to 3D Retinal Organoids Derived from Human Induced Pluripotent Stem Cells International Journal of Molecular Sciences. Feb, 2020 | Pubmed ID: 32028585 Opsins for Vision Restoration Biochemical and Biophysical Research Communications. 06, 2020 | Pubmed ID: 31982136 ATTENUATION OUTER RETINAL BANDS ON OPTICAL COHERENCE TOMOGRAPHY FOLLOWING MACULAR EDEMA: A Possible Manifestation of Photoreceptor Misalignment Retina (Philadelphia, Pa.). Nov, 2020 | Pubmed ID: 31922497 IL-1β Induces Rod Degeneration Through the Disruption of Retinal Glutamate Homeostasis Journal of Neuroinflammation. Jan, 2020 | Pubmed ID: 31900165 Behavioural Responses to a Photovoltaic Subretinal Prosthesis Implanted in Non-human Primates Nature Biomedical Engineering. 02, 2020 | Pubmed ID: 31792423 Clinical-grade Production and Safe Delivery of Human ESC Derived RPE Sheets in Primates and Rodents Biomaterials. 02, 2020 | Pubmed ID: 31732225 Age-related Preference for Geometric Spatial Cues During Real-world Navigation Nature Human Behaviour. 01, 2020 | Pubmed ID: 31548677 Effect of Visual Search Training on Saccades in Age-related Macular Degeneration Subjects Current Aging Science. 2020 | Pubmed ID: 31518228 PHENOTYPIC CHARACTERISTICS OF ROD-CONE DYSTROPHY ASSOCIATED WITH MYO7A MUTATIONS IN A LARGE FRENCH COHORT Retina (Philadelphia, Pa.). Aug, 2020 | Pubmed ID: 31479088 CD36 Deficiency Inhibits Retinal Inflammation and Retinal Degeneration in Knockout Mice Frontiers in Immunology. 2019 | Pubmed ID: 31969887 The Primate Model for Understanding and Restoring Vision Proceedings of the National Academy of Sciences of the United States of America. Dec, 2019 | Pubmed ID: 31871177 Implications of Monocular Vision for Racing Drivers PloS One. 2019 | Pubmed ID: 31841526 Peripapillary Sparing With Near Infrared Autofluorescence Correlates With Electroretinographic Findings in Patients With Stargardt Disease Investigative Ophthalmology & Visual Science. 12, 2019 | Pubmed ID: 31790517 Generation of Human Induced Pluripotent Stem Cell Lines from a Patient with ITM2B-related Retinal Dystrophy and a Non Mutated Brother Stem Cell Research. 12, 2019 | Pubmed ID: 31731182 Ocular Injuries Caused by Less-lethal Weapons in France Lancet (London, England). 11, 2019 | Pubmed ID: 31690443 Waveform Analysis of Human Retinal and Choroidal Blood Flow with Laser Doppler Holography Biomedical Optics Express. Oct, 2019 | Pubmed ID: 31646021 Prevalence of Deep-Intronic Variants and Related Phenotype in An Unsolved "One-Hit" Cohort with Stargardt Disease International Journal of Molecular Sciences. Oct, 2019 | Pubmed ID: 31614660 Restoration of Visual Function by Transplantation of Optogenetically Engineered Photoreceptors Nature Communications. 10, 2019 | Pubmed ID: 31586094 Phenotype Analysis of Retinal Dystrophies in Light of the Underlying Genetic Defects: Application to Cone and Cone-Rod Dystrophies International Journal of Molecular Sciences. Sep, 2019 | Pubmed ID: 31574917 Outer Retinal Alterations Associated With Visual Outcomes in Best Vitelliform Macular Dystrophy American Journal of Ophthalmology. 12, 2019 | Pubmed ID: 31465755 Progression of Stargardt Disease As Determined by Fundus Autofluorescence Over a 12-Month Period: ProgStar Report No. 11 JAMA Ophthalmology. Aug, 2019 | Pubmed ID: 31369039 Mo-derived Perivascular Macrophage Recruitment Protects Against Endothelial Cell Death in Retinal Vein Occlusion Journal of Neuroinflammation. Jul, 2019 | Pubmed ID: 31351497 Full-field Electroretinography, Visual Acuity and Visual Fields in Usher Syndrome: a Multicentre European Study Documenta Ophthalmologica. Advances in Ophthalmology. 10, 2019 | Pubmed ID: 31267413 Carotenoid Composition and Conformation in Retinal Oil Droplets of the Domestic Chicken PloS One. 2019 | Pubmed ID: 31150434 Depicting Brighter Possibilities for Treating Blindness Science Translational Medicine. 05, 2019 | Pubmed ID: 31142676 Identification of a Novel GRM6 Mutation in a Previously Described Consanguineous Family with Complete Congenital Stationary Night Blindness Ophthalmic Genetics. 04, 2019 | Pubmed ID: 31063016 Longitudinal Clinical Follow-up and Genetic Spectrum of Patients With Rod-Cone Dystrophy Associated With Mutations in PDE6A and PDE6B JAMA Ophthalmology. 06, 2019 | Pubmed ID: 30998820 Functional Ultrasound Imaging of the Brain Reveals Propagation of Task-related Brain Activity in Behaving Primates Nature Communications. 03, 2019 | Pubmed ID: 30923310 A Mathematical Analysis of Aerobic Glycolysis Triggered by Glucose Uptake in Cones Scientific Reports. 03, 2019 | Pubmed ID: 30858444 Where Are the Missing Gene Defects in Inherited Retinal Disorders? Intronic and Synonymous Variants Contribute at Least to 4% of CACNA1F-mediated Inherited Retinal Disorders Human Mutation. 06, 2019 | Pubmed ID: 30825406 Choroidal Vasculature Imaging with Laser Doppler Holography Biomedical Optics Express. Feb, 2019 | Pubmed ID: 30800528 The Development of White Matter Structural Changes During the Process of Deterioration of the Visual Field Scientific Reports. 02, 2019 | Pubmed ID: 30765782 Immune Response and Intraocular Inflammation in Patients With Leber Hereditary Optic Neuropathy Treated With Intravitreal Injection of Recombinant Adeno-Associated Virus 2 Carrying the ND4 Gene: A Secondary Analysis of a Phase 1/2 Clinical Trial JAMA Ophthalmology. 04, 2019 | Pubmed ID: 30730541 Gene Therapy for Retinal Dystrophy Nature Medicine. 02, 2019 | Pubmed ID: 30718907 Effects of Corneal Injury on Ciliary Nerve Fibre Activity and Corneal Nociception in Mice: A Behavioural and Electrophysiological Study European Journal of Pain (London, England). 03, 2019 | Pubmed ID: 30370980 Whole Exome Sequencing Resolves Complex Phenotype and Identifies CC2D2A Mutations Underlying Non-syndromic Rod-cone Dystrophy Clinical Genetics. 02, 2019 | Pubmed ID: 30267408 Scotopic Microperimetric Assessment of Rod Function in Stargardt Disease (SMART) Study: Design and Baseline Characteristics (Report No. 1) Ophthalmic Research. 2019 | Pubmed ID: 29940588 AUTOSOMAL DOMINANT VITREORETINOCHOROIDOPATHY: When Molecular Genetic Testing Helps Clinical Diagnosis Retina (Philadelphia, Pa.). May, 2019 | Pubmed ID: 29370033 Adapted Surgical Procedure for Argus II Retinal Implantation: Feasibility, Safety, Efficiency, and Postoperative Anatomic Findings Ophthalmology. Retina. 04, 2018 | Pubmed ID: 31047236 Optogenetic Light Sensors in Human Retinal Organoids Frontiers in Neuroscience. 2018 | Pubmed ID: 30450028 Translational Retinal Research and Therapies Translational Vision Science & Technology. Sep, 2018 | Pubmed ID: 30225158 Correlation Between Visual Function and Performance of Simulated Daily Living Activities in Glaucomatous Patients Journal of Glaucoma. 11, 2018 | Pubmed ID: 30157061 Characterization and Transplantation of CD73-Positive Photoreceptors Isolated from Human IPSC-Derived Retinal Organoids Stem Cell Reports. Jul, 2018 | Pubmed ID: 30100409 Expanding the Mutation Spectrum in : Sixty Novel Disease Causing Variants and Their Associated Phenotype in a Large French Stargardt Cohort International Journal of Molecular Sciences. Jul, 2018 | Pubmed ID: 30060493 Visual Brain Plasticity Induced by Central and Peripheral Visual Field Loss Brain Structure & Function. Sep, 2018 | Pubmed ID: 29936553 Restoring Vision Nature. May, 2018 | Pubmed ID: 29769667 Phenotypic Characteristics of a French Cohort of Patients with X-Linked Retinoschisis Ophthalmology. 10, 2018 | Pubmed ID: 29739629 Maintaining Cone Function in Rod-Cone Dystrophies Advances in Experimental Medicine and Biology. 2018 | Pubmed ID: 29721982 Dietary, Environmental, and Genetic Risk Factors of Extensive Macular Atrophy with Pseudodrusen, a Severe Bilateral Macular Atrophy of Middle-aged Patients Scientific Reports. 05, 2018 | Pubmed ID: 29717154 MERTK Mutation Update in Inherited Retinal Diseases Human Mutation. 07, 2018 | Pubmed ID: 29659094 Multimodal Imaging Including Semiquantitative Short-wavelength and Near-infrared Autofluorescence in Achromatopsia Scientific Reports. 04, 2018 | Pubmed ID: 29618791 Chronic Exposure to Tumor Necrosis Factor Alpha Induces Retinal Pigment Epithelium Cell Dedifferentiation Journal of Neuroinflammation. Mar, 2018 | Pubmed ID: 29548329 Light Action Spectrum on Oxidative Stress and Mitochondrial Damage in A2E-loaded Retinal Pigment Epithelium Cells Cell Death & Disease. 02, 2018 | Pubmed ID: 29459695 Safety of RAAV2/2-ND4 Gene Therapy for Leber Hereditary Optic Neuropathy Ophthalmology. 06, 2018 | Pubmed ID: 29426586 Noninvasive Gene Delivery to Foveal Cones for Vision Restoration JCI Insight. 01, 2018 | Pubmed ID: 29367457 Otx2-Genetically Modified Retinal Pigment Epithelial Cells Rescue Photoreceptors After Transplantation Molecular Therapy : the Journal of the American Society of Gene Therapy. 01, 2018 | Pubmed ID: 28988713 [Age-related Macular Degeneration Diagnosis] La Revue Du Praticien. 01, 2017 | Pubmed ID: 30512446 [Age-related Macular Degeneration] La Revue Du Praticien. 01, 2017 | Pubmed ID: 30512444 Human ESC-derived Retinal Epithelial Cell Sheets Potentiate Rescue of Photoreceptor Cell Loss in Rats with Retinal Degeneration Science Translational Medicine. Dec, 2017 | Pubmed ID: 29263231 Further Insights into the Ciliary Gene and Protein KIZ and Its Murine Ortholog PLK1S1 Mutated in Rod-Cone Dystrophy Genes. Oct, 2017 | Pubmed ID: 29057815 Establishment of an Induced Pluripotent Stem (iPS) Cell Line from Dermal Fibroblasts of an Asymptomatic Patient with Dominant PRPF31 Mutation Stem Cell Research. Dec, 2017 | Pubmed ID: 29040912 Generation of an Induced Pluripotent Stem Cell (iPSC) Line from a Patient with Autosomal Dominant Retinitis Pigmentosa Due to a Mutation in the NR2E3 Gene Stem Cell Research. 10, 2017 | Pubmed ID: 29034877 Taurine Promotes Retinal Ganglion Cell Survival Through GABA Receptor Activation Advances in Experimental Medicine and Biology. 2017 | Pubmed ID: 28849492 A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina Molecular Therapy : the Journal of the American Society of Gene Therapy. Nov, 2017 | Pubmed ID: 28807567 Adaptive Gaze Strategies for Locomotion with Constricted Visual Field Frontiers in Human Neuroscience. 2017 | Pubmed ID: 28798674 On Phagocytes and Macular Degeneration Progress in Retinal and Eye Research. Nov, 2017 | Pubmed ID: 28602950 Usher Syndrome Type 1-associated Cadherins Shape the Photoreceptor Outer Segment The Journal of Cell Biology. 06, 2017 | Pubmed ID: 28495838 Novel Splice-site Mutation in TTLL5 Causes Cone Dystrophy in a Consanguineous Family Molecular Vision. 2017 | Pubmed ID: 28356705 LRIT3 Differentially Affects Connectivity and Synaptic Transmission of Cones to ON- and OFF-Bipolar Cells Investigative Ophthalmology & Visual Science. Mar, 2017 | Pubmed ID: 28334377 Impact of Retinitis Pigmentosa on Quality of Life, Mental Health, and Employment Among Young Adults American Journal of Ophthalmology. May, 2017 | Pubmed ID: 28237413 Reorganization of Early Visual Cortex Functional Connectivity Following Selective Peripheral and Central Visual Loss Scientific Reports. 02, 2017 | Pubmed ID: 28233790 Complement Factor H Inhibits CD47-Mediated Resolution of Inflammation Immunity. 02, 2017 | Pubmed ID: 28228282 Generation of Storable Retinal Organoids and Retinal Pigmented Epithelium from Adherent Human IPS Cells in Xeno-Free and Feeder-Free Conditions Stem Cells (Dayton, Ohio). 05, 2017 | Pubmed ID: 28220575 3D Functional Ultrasound Imaging of the Cerebral Visual System in Rodents NeuroImage. 04, 2017 | Pubmed ID: 28167348 Col4a1 Mutation Generates Vascular Abnormalities Correlated with Neuronal Damage in a Mouse Model of HANAC Syndrome Neurobiology of Disease. Apr, 2017 | Pubmed ID: 28057519 Lebecetin, a C-type Lectin, Inhibits Choroidal and Retinal Neovascularization FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 03, 2017 | Pubmed ID: 27974593 Activated Monocytes Resist Elimination by Retinal Pigment Epithelium and Downregulate Their OTX2 Expression Via TNF-α Aging Cell. Feb, 2017 | Pubmed ID: 27660103 Metabolic and Redox Signaling in the Retina Cellular and Molecular Life Sciences : CMLS. 10, 2017 | Pubmed ID: 27543457 Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors Against A2E-Mediated Phototoxicity In Vitro and In Vivo PloS One. 2016 | Pubmed ID: 27992460 Identification of a Novel Homozygous Nonsense Mutation Confirms the Implication of GNAT1 in Rod-Cone Dystrophy PloS One. 2016 | Pubmed ID: 27977773 Emerging Therapies for Inherited Retinal Degeneration Science Translational Medicine. 12, 2016 | Pubmed ID: 27928030 Quantitative and Topographical Analysis of the Losses of Cone Photoreceptors and Retinal Ganglion Cells Under Taurine Depletion Investigative Ophthalmology & Visual Science. 09, 2016 | Pubmed ID: 27607415 A New Autosomal Dominant Eye and Lung Syndrome Linked to Mutations in TIMP3 Gene Scientific Reports. Sep, 2016 | Pubmed ID: 27601084 Argus II Retinal Prosthesis Implantation with Scleral Flap and Autogenous Temporalis Fascia As Alternative Patch Graft Material: a 4-year Follow-up Clinical Ophthalmology (Auckland, N.Z.). 2016 | Pubmed ID: 27574397 Martinique Crinkled Retinal Pigment Epitheliopathy: Clinical Stages and Pathophysiologic Insights Ophthalmology. Oct, 2016 | Pubmed ID: 27474146 An Innovative Strategy for the Molecular Diagnosis of Usher Syndrome Identifies Causal Biallelic Mutations in 93% of European Patients European Journal of Human Genetics : EJHG. 12, 2016 | Pubmed ID: 27460420 Five-Year Safety and Performance Results from the Argus II Retinal Prosthesis System Clinical Trial Ophthalmology. 10, 2016 | Pubmed ID: 27453256 Mathematical Model of the Role of RdCVF in the Coexistence of Rods and Cones in a Healthy Eye Bulletin of Mathematical Biology. 07, 2016 | Pubmed ID: 27444436 Subretinal Mononuclear Phagocytes Induce Cone Segment Loss Via IL-1β ELife. 07, 2016 | Pubmed ID: 27438413 Visual Acuity Loss and Associated Risk Factors in the Retrospective Progression of Stargardt Disease Study (ProgStar Report No. 2) Ophthalmology. 09, 2016 | Pubmed ID: 27378015 Clinical Characteristics and Risk Factors of Extensive Macular Atrophy with Pseudodrusen: The EMAP Case-Control National Clinical Trial Ophthalmology. Sep, 2016 | Pubmed ID: 27320518 AAV-mediated Gene Therapy in Dystrophin-Dp71 Deficient Mouse Leads to Blood-retinal Barrier Restoration and Oedema Reabsorption Human Molecular Genetics. 07, 2016 | Pubmed ID: 27288449 Insight into the Mechanisms of Enhanced Retinal Transduction by the Engineered AAV2 Capsid Variant -7m8 Biotechnology and Bioengineering. 12, 2016 | Pubmed ID: 27259396 Increased Functional Connectivity Between Language and Visually Deprived Areas in Late and Partial Blindness NeuroImage. Aug, 2016 | Pubmed ID: 27143090 Biallelic Mutations in GNB3 Cause a Unique Form of Autosomal-Recessive Congenital Stationary Night Blindness American Journal of Human Genetics. May, 2016 | Pubmed ID: 27063057 The Thioredoxin Encoded by the Rod-Derived Cone Viability Factor Gene Protects Cone Photoreceptors Against Oxidative Stress Antioxidants & Redox Signaling. 06, 2016 | Pubmed ID: 27025156 Identification of an Alternative Splicing Product of the Otx2 Gene Expressed in the Neural Retina and Retinal Pigmented Epithelial Cells PloS One. 2016 | Pubmed ID: 26985665 Run of Homozygosity Analysis Reveals a Novel Nonsense Variant of the CNGB1 Gene Involved in Retinitis Pigmentosa 45 Ophthalmic Genetics. 09, 2016 | Pubmed ID: 26901671 The Natural History of the Progression of Atrophy Secondary to Stargardt Disease (ProgStar) Studies: Design and Baseline Characteristics: ProgStar Report No. 1 Ophthalmology. Apr, 2016 | Pubmed ID: 26786511 Let There Be Light: Gene and Cell Therapy for Blindness Human Gene Therapy. Feb, 2016 | Pubmed ID: 26751519 Ocular Inflammation Induces Trigeminal Pain, Peripheral and Central Neuroinflammatory Mechanisms Neurobiology of Disease. Apr, 2016 | Pubmed ID: 26747211 Altered Astrocyte Morphology and Vascular Development in Dystrophin-Dp71-null Mice Glia. May, 2016 | Pubmed ID: 26711882 A Large Genome-wide Association Study of Age-related Macular Degeneration Highlights Contributions of Rare and Common Variants Nature Genetics. Feb, 2016 | Pubmed ID: 26691988 Functional and High-resolution Retinal Imaging Monitoring Photoreceptor Damage in Acute Macular Neuroretinopathy Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. May, 2016 | Pubmed ID: 26344727 Novel Grading System for Quantification of Cystic Macular Lesions in Usher Syndrome Orphanet Journal of Rare Diseases. Dec, 2015 | Pubmed ID: 26654877 [Altruism in the Retina: Sticks Feed Cones] Medecine Sciences : M/S. Oct, 2015 | Pubmed ID: 26481018 APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2015 | Pubmed ID: 26446211 Intraocular Pressure Reduction and Neuroprotection Conferred by Bone Marrow-derived Mesenchymal Stem Cells in an Animal Model of Glaucoma Stem Cell Research & Therapy. Sep, 2015 | Pubmed ID: 26377305 Structure and Conformation of the Carotenoids in Human Retinal Macular Pigment PloS One. 2015 | Pubmed ID: 26313550 Synthetic 3D Diamond-based Electrodes for Flexible Retinal Neuroprostheses: Model, Production and In vivo Biocompatibility Biomaterials. Oct, 2015 | Pubmed ID: 26210174 Experimental Branch Retinal Vein Occlusion Induces Upstream Pericyte Loss and Vascular Destabilization PloS One. 2015 | Pubmed ID: 26208283 Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind Ophthalmology. Aug, 2015 | Pubmed ID: 26162233 Foxg1-Cre Mediated Lrp2 Inactivation in the Developing Mouse Neural Retina, Ciliary and Retinal Pigment Epithelia Models Congenital High Myopia PloS One. 2015 | Pubmed ID: 26107939 Next-generation Sequencing Applied to a Large French Cone and Cone-rod Dystrophy Cohort: Mutation Spectrum and New Genotype-phenotype Correlation Orphanet Journal of Rare Diseases. Jun, 2015 | Pubmed ID: 26103963 Combined 3DISCO Clearing Method, Retrograde Tracer and Ultramicroscopy to Map Corneal Neurons in a Whole Adult Mouse Trigeminal Ganglion Experimental Eye Research. Oct, 2015 | Pubmed ID: 26072022 Genotypic and Phenotypic Characterization of P23H Line 1 Rat Model PloS One. 2015 | Pubmed ID: 26009893 LRIT3 is Essential to Localize TRPM1 to the Dendritic Tips of Depolarizing Bipolar Cells and May Play a Role in Cone Synapse Formation The European Journal of Neuroscience. Aug, 2015 | Pubmed ID: 25997951 Rod-derived Cone Viability Factor Promotes Cone Survival by Stimulating Aerobic Glycolysis Cell. May, 2015 | Pubmed ID: 25957687 Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2015 | Pubmed ID: 25948251 Dystrophin Dp71 Gene Deletion Induces Retinal Vascular Inflammation and Capillary Degeneration Human Molecular Genetics. Jul, 2015 | Pubmed ID: 25901007 Sildenafil Acutely Decreases Visual Responses in ON and OFF Retinal Ganglion Cells Investigative Ophthalmology & Visual Science. Mar, 2015 | Pubmed ID: 25814000 Optogenetics Current Opinion in Ophthalmology. May, 2015 | Pubmed ID: 25759964 Targeted Next Generation Sequencing Identifies Novel Mutations in RP1 As a Relatively Common Cause of Autosomal Recessive Rod-cone Dystrophy BioMed Research International. 2015 | Pubmed ID: 25692139 Repair of Rhodopsin MRNA by Spliceosome-Mediated RNA Trans-Splicing: A New Approach for Autosomal Dominant Retinitis Pigmentosa Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2015 | Pubmed ID: 25619725 Late Posterior Segment Relapses in a Series of Vogt-Koyanagi-Harada Disease Acta Ophthalmologica. Jan, 2015 | Pubmed ID: 25604241 Apolipoprotein E Promotes Subretinal Mononuclear Phagocyte Survival and Chronic Inflammation in Age-related Macular Degeneration EMBO Molecular Medicine. 2015 | Pubmed ID: 25604058 Gene Therapy for the Eye Focus on Mutation-independent Approaches Current Opinion in Neurology. Feb, 2015 | Pubmed ID: 25545056 Cleavage of Mer Tyrosine Kinase (MerTK) from the Cell Surface Contributes to the Regulation of Retinal Phagocytosis The Journal of Biological Chemistry. Feb, 2015 | Pubmed ID: 25538233 High Prevalence of PRPH2 in Autosomal Dominant Retinitis Pigmentosa in France and Characterization of Biochemical and Clinical Features American Journal of Ophthalmology. Feb, 2015 | Pubmed ID: 25447119 Viral-mediated RdCVF and RdCVFL Expression Protects Cone and Rod Photoreceptors in Retinal Degeneration The Journal of Clinical Investigation. Jan, 2015 | Pubmed ID: 25415434 Clinical Characteristics and Current Therapies for Inherited Retinal Degenerations Cold Spring Harbor Perspectives in Medicine. Feb, 2015 | Pubmed ID: 25324231 Mutations in IFT172 Cause Isolated Retinal Degeneration and Bardet-Biedl Syndrome Human Molecular Genetics. Jan, 2015 | Pubmed ID: 25168386 Targeting Channelrhodopsin-2 to ON-bipolar Cells with Vitreally Administered AAV Restores ON and OFF Visual Responses in Blind Mice Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2015 | Pubmed ID: 25095892 Lack of Dystrophin Protein Dp71 Results in Progressive Cataract Formation Due to Loss of Fiber Cell Organization Molecular Vision. 2014 | Pubmed ID: 25489223 Ocular Tuberculosis: Experience of an Italian and French Cohort Acta Ophthalmologica. Dec, 2014 | Pubmed ID: 25488026 Importance of Eye Position on Spatial Localization in Blind Subjects Wearing an Argus II Retinal Prosthesis Investigative Ophthalmology & Visual Science. Dec, 2014 | Pubmed ID: 25414187 Determination of Morphological, Biometric and Biochemical Susceptibilities in Healthy Eurasier Dogs with Suspected Inherited Glaucoma PloS One. 2014 | Pubmed ID: 25380252 Rods in Daylight Act As Relay Cells for Cone-driven Horizontal Cell-mediated Surround Inhibition Nature Neuroscience. Dec, 2014 | Pubmed ID: 25344628 [Production of in Vitro Retina from Pluripotent Human Stem Cells: a New Therapeutic Tool] Médecine Sciences : M/S. Oct, 2014 | Pubmed ID: 25311017 "En Face" Optical Coherence Tomography Imaging in Type 2 Idiopathic Macular Telangiectasia Retina (Philadelphia, Pa.). Oct, 2014 | Pubmed ID: 25255245 A Neurological Disorder Presumably Underlies Painter Francis Bacon Distorted World Depiction Frontiers in Human Neuroscience. 2014 | Pubmed ID: 25221491 From Confluent Human IPS Cells to Self-forming Neural Retina and Retinal Pigmented Epithelium Proceedings of the National Academy of Sciences of the United States of America. Jun, 2014 | Pubmed ID: 24912154 "En-face" Spectral-domain Optical Coherence Tomography Findings in Multiple Evanescent White Dot Syndrome Journal of Ophthalmology. 2014 | Pubmed ID: 24864197 Spectral-domain Optical Coherence Tomography of the Rodent Eye: Highlighting Layers of the Outer Retina Using Signal Averaging and Comparison with Histology PloS One. 2014 | Pubmed ID: 24788712 Reply: To PMID 23591533 Retina (Philadelphia, Pa.). May, 2014 | Pubmed ID: 24751952 The Cost-effectiveness of the Argus II Retinal Prosthesis in Retinitis Pigmentosa Patients BMC Ophthalmology. 2014 | Pubmed ID: 24731533 Taurine: the Comeback of a Neutraceutical in the Prevention of Retinal Degenerations Progress in Retinal and Eye Research. Jul, 2014 | Pubmed ID: 24721186 Retinal Prostheses: Clinical Results and Future Challenges Comptes Rendus Biologies. Mar, 2014 | Pubmed ID: 24702848 Therapeutic Strategy for Handling Inherited Retinal Degenerations in a Gene-independent Manner Using Rod-derived Cone Viability Factors Comptes Rendus Biologies. Mar, 2014 | Pubmed ID: 24702847 Gene Therapy for Mitochondrial Diseases: Leber Hereditary Optic Neuropathy As the First Candidate for a Clinical Trial Comptes Rendus Biologies. Mar, 2014 | Pubmed ID: 24702846 Gene Therapy for Inherited Retinal Degenerations Comptes Rendus Biologies. Mar, 2014 | Pubmed ID: 24702845 Spotlight on Vision Comptes Rendus Biologies. Mar, 2014 | Pubmed ID: 24702840 Microcystic Changes in the Retinal Internal Nuclear Layer Associated with Optic Atrophy: a Prospective Study Journal of Ophthalmology. 2014 | Pubmed ID: 24701345 Cell Specific Electrodes for Neuronal Network Reconstruction and Monitoring The Analyst. Jul, 2014 | Pubmed ID: 24699623 Whole-exome Sequencing Identifies KIZ As a Ciliary Gene Associated with Autosomal-recessive Rod-cone Dystrophy American Journal of Human Genetics. Apr, 2014 | Pubmed ID: 24680887 Distinctive Glial and Neuronal Interfacing on Nanocrystalline Diamond PloS One. 2014 | Pubmed ID: 24664111 Increased Optic Nerve Radiosensitivity Following Optic Neuritis Neurology. Apr, 2014 | Pubmed ID: 24658931 Neuroglobin Gene Therapy Prevents Optic Atrophy and Preserves Durably Visual Function in Harlequin Mice Molecular Therapy : the Journal of the American Society of Gene Therapy. Jun, 2014 | Pubmed ID: 24622090 Lrit3 Deficient Mouse (nob6): a Novel Model of Complete Congenital Stationary Night Blindness (cCSNB) PloS One. 2014 | Pubmed ID: 24598786 Retinal Vasculitis Imaging by Adaptive Optics Ophthalmology. Jun, 2014 | Pubmed ID: 24576889 Involvement of Bcl-2-associated Transcription Factor 1 in the Differentiation of Early-born Retinal Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2014 | Pubmed ID: 24453340 Morphometric Analysis of Small Arteries in the Human Retina Using Adaptive Optics Imaging: Relationship with Blood Pressure and Focal Vascular Changes Journal of Hypertension. Apr, 2014 | Pubmed ID: 24406779 AAV-mediated Gene Delivery in Dp71-null Mouse Model with Compromised Barriers Glia. Mar, 2014 | Pubmed ID: 24382652 Toward Postnatal Reversal of Ocular Congenital Malformations The Journal of Clinical Investigation. Jan, 2014 | Pubmed ID: 24355915 Functional and High Resolution Retinal Imaging Assessment in a Case of Ocular Siderosis Documenta Ophthalmologica. Advances in Ophthalmology. Feb, 2014 | Pubmed ID: 24337723 The Familial Dementia Gene Revisited: a Missense Mutation Revealed by Whole-exome Sequencing Identifies ITM2B As a Candidate Gene Underlying a Novel Autosomal Dominant Retinal Dystrophy in a Large Family Human Molecular Genetics. Jan, 2014 | Pubmed ID: 24026677 Neonatal Hyperglycemia Inhibits Angiogenesis and Induces Inflammation and Neuronal Degeneration in the Retina PloS One. 2013 | Pubmed ID: 24278148 Further Insights into GPR179: Expression, Localization, and Associated Pathogenic Mechanisms Leading to Complete Congenital Stationary Night Blindness Investigative Ophthalmology & Visual Science. Dec, 2013 | Pubmed ID: 24222301 CCR2(+) Monocytes Infiltrate Atrophic Lesions in Age-related Macular Disease and Mediate Photoreceptor Degeneration in Experimental Subretinal Inflammation in Cx3cr1 Deficient Mice EMBO Molecular Medicine. Nov, 2013 | Pubmed ID: 24142887 [Restoring Vision in Blind Patients Following Photoreceptor Degeneration: Clinical Results and Future Challenges] Biologie Aujourd'hui. 2013 | Pubmed ID: 24103342 [Retinitis Pigmentosa: Eye Sight Restoration by Optogenetic Therapy] Biologie Aujourd'hui. 2013 | Pubmed ID: 24103341 Phototoxic Action Spectrum on a Retinal Pigment Epithelium Model of Age-related Macular Degeneration Exposed to Sunlight Normalized Conditions PloS One. 2013 | Pubmed ID: 24058402 Mutations in IMPG1 Cause Vitelliform Macular Dystrophies American Journal of Human Genetics. Sep, 2013 | Pubmed ID: 23993198 Disease-causing Mutations in BEST1 Gene Are Associated with Altered Sorting of Bestrophin-1 Protein International Journal of Molecular Sciences. 2013 | Pubmed ID: 23880862 Outer Retinal Tubulations in Serpinginous Choroiditis Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Nov, 2013 | Pubmed ID: 23839703 Retinal and Choroidal Changes Observed with 'En Face' Enhanced-depth Imaging OCT in Central Serous Chorioretinopathy The British Journal of Ophthalmology. Sep, 2013 | Pubmed ID: 23823080 Genetic Association Study of Mitochondrial Polymorphisms in Neovascular Age-related Macular Degeneration Molecular Vision. 2013 | Pubmed ID: 23734082 Gene Therapy for Blindness Annual Review of Neuroscience. Jul, 2013 | Pubmed ID: 23724995 Retinal Inner Nuclear Layer Microcystic Changes in Optic Nerve Atrophy: a Novel Spectral-domain OCT Finding Retina (Philadelphia, Pa.). Nov-Dec, 2013 | Pubmed ID: 23644558 Neuroglobin Involvement in Visual Pathways Through the Optic Nerve Biochimica Et Biophysica Acta. Sep, 2013 | Pubmed ID: 23639750 Adaptive Optics Imaging of Geographic Atrophy Investigative Ophthalmology & Visual Science. May, 2013 | Pubmed ID: 23620431 A Single Intravenous AAV9 Injection Mediates Bilateral Gene Transfer to the Adult Mouse Retina PloS One. 2013 | Pubmed ID: 23613884 Using Spectral-domain Optical Coherence Tomography Imaging to Identify the Presence of Retinal Silicone Oil Emulsification After Silicone Oil Tamponade Retina (Philadelphia, Pa.). Sep, 2013 | Pubmed ID: 23591533 In Vitro Toxicological Assessment of Clays for Their Use in Food Packaging Applications Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Jul, 2013 | Pubmed ID: 23579166 Functional Rescue of Cone Photoreceptors in Retinitis Pigmentosa Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Jul, 2013 | Pubmed ID: 23575948 A Semi-automated Computer Tool for the Analysis of Retinal Vessel Diameter Dynamics Computers in Biology and Medicine. Jun, 2013 | Pubmed ID: 23566397 The Detection of Motion by Blind Subjects With the Epiretinal 60-Electrode (Argus II) Retinal Prosthesis JAMA Ophthalmology. Feb, 2013 | Pubmed ID: 23544203 [Therapeutic Innovation in AMD and Other Retinal Diseases] La Revue Du Praticien. Jan, 2013 | Pubmed ID: 23457831 [Ophthalmology, Between Spectacular Advances and Gaps in Managed Care] La Revue Du Praticien. Jan, 2013 | Pubmed ID: 23457825 Seven New Loci Associated with Age-related Macular Degeneration Nature Genetics. Apr, 2013 | Pubmed ID: 23455636 Evaluation of the Taurine Concentrations in Dog Plasma and Aqueous Humour: a Pilot Study Advances in Experimental Medicine and Biology. 2013 | Pubmed ID: 23392931 Taurine is a Crucial Factor to Preserve Retinal Ganglion Cell Survival Advances in Experimental Medicine and Biology. 2013 | Pubmed ID: 23392925 Relative Frequencies of Inherited Retinal Dystrophies and Optic Neuropathies in Southern France: Assessment of 21-year Data Management Ophthalmic Epidemiology. 2013 | Pubmed ID: 23350551 Findings in Detection of Herpesviridae by Polymerase Chain Reaction and Intraocular Antibody Production in a Case Series of Anterior Uveitis Ocular Immunology and Inflammation. 2013 | Pubmed ID: 23323583 Whole-exome Sequencing Identifies LRIT3 Mutations As a Cause of Autosomal-recessive Complete Congenital Stationary Night Blindness American Journal of Human Genetics. Jan, 2013 | Pubmed ID: 23246293 Presence and Bioaccumulation of Microcystins and Cylindrospermopsin in Food and the Effectiveness of Some Cooking Techniques at Decreasing Their Concentrations: a Review Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association. Mar, 2013 | Pubmed ID: 23200893 Neural Stimulation for Visual Rehabilitation: Advances and Challenges Journal of Physiology, Paris. Nov, 2013 | Pubmed ID: 23148976 Dry Age-related Macular Degeneration: A Currently Unmet Clinical Need Intractable & Rare Diseases Research. Aug, 2012 | Pubmed ID: 25343081 Taurine Provides Neuroprotection Against Retinal Ganglion Cell Degeneration PloS One. 2012 | Pubmed ID: 23115615 Localization of Usher 1 Proteins to the Photoreceptor Calyceal Processes, Which Are Absent from Mice The Journal of Cell Biology. Oct, 2012 | Pubmed ID: 23045546 Neuroglobin Involvement in Respiratory Chain Function and Retinal Ganglion Cell Integrity Biochimica Et Biophysica Acta. Dec, 2012 | Pubmed ID: 23036890 En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration Journal of Ophthalmology. 2012 | Pubmed ID: 22970349 Influence of the Exposure Way and the Time of Sacrifice on the Effects Induced by a Single Dose of Pure Cylindrospermopsin on the Activity and Transcription of Glutathione Peroxidase and Glutathione-S-transferase Enzymes in Tilapia (Oreochromis Niloticus) Chemosphere. Jul, 2012 | Pubmed ID: 22850279 NMNAT1 Mutations Cause Leber Congenital Amaurosis Nature Genetics. Sep, 2012 | Pubmed ID: 22842227 Alterations Observed in the Endothelial HUVEC Cell Line Exposed to Pure Cylindrospermopsin Chemosphere. Jul, 2012 | Pubmed ID: 22818884 Treating Retinal Vein Occlusions in France, Germany, and Italy: an Analysis of Treatment Patterns, Resource Consumption, and Costs European Journal of Ophthalmology. Sep-Oct, 2012 | Pubmed ID: 22729442 Genome-wide Association Study of Age-related Macular Degeneration Identifies Associated Variants in the TNXB-FKBPL-NOTCH4 Region of Chromosome 6p21.3 Human Molecular Genetics. Sep, 2012 | Pubmed ID: 22694956 Spectral Domain Optical Coherence Tomography Evolutive Features in Acute Macular Neuroretinopathy European Journal of Ophthalmology. Sep-Oct, 2012 | Pubmed ID: 22610717 Protective Role of Dietary N-acetylcysteine on the Oxidative Stress Induced by Cylindrospermopsin in Tilapia (Oreochromis Niloticus) Environmental Toxicology and Chemistry / SETAC. Jul, 2012 | Pubmed ID: 22511408 Taurine Deficiency Damages Retinal Neurones: Cone Photoreceptors and Retinal Ganglion Cells Amino Acids. Nov, 2012 | Pubmed ID: 22476345 Oxidative Stress Responses to Carboxylic Acid Functionalized Single Wall Carbon Nanotubes on the Human Intestinal Cell Line Caco-2 Toxicology in Vitro : an International Journal Published in Association with BIBRA. Aug, 2012 | Pubmed ID: 22449549 Temporal Properties of Visual Perception on Electrical Stimulation of the Retina Investigative Ophthalmology & Visual Science. May, 2012 | Pubmed ID: 22447863 Nxnl2 Splicing Results in Dual Functions in Neuronal Cell Survival and Maintenance of Cell Integrity Human Molecular Genetics. May, 2012 | Pubmed ID: 22343139 Acute Exposure to Pure Cylindrospermopsin Results in Oxidative Stress and Pathological Alterations in Tilapia (Oreochromis Niloticus) Environmental Toxicology. Feb, 2012 | Pubmed ID: 22331699 Whole-exome Sequencing Identifies Mutations in GPR179 Leading to Autosomal-recessive Complete Congenital Stationary Night Blindness American Journal of Human Genetics. Feb, 2012 | Pubmed ID: 22325361 Development and Application of a Next-generation-sequencing (NGS) Approach to Detect Known and Novel Gene Defects Underlying Retinal Diseases Orphanet Journal of Rare Diseases. 2012 | Pubmed ID: 22277662 Interim Results from the International Trial of Second Sight's Visual Prosthesis Ophthalmology. Apr, 2012 | Pubmed ID: 22244176 Biochemical and Pathological Toxic Effects Induced by the Cyanotoxin Cylindrospermopsin on the Human Cell Line Caco-2 Water Research. Apr, 2012 | Pubmed ID: 22227240 Downregulation of Apoptosis-inducing Factor in Harlequin Mice Induces Progressive and Severe Optic Atrophy Which is Durably Prevented by AAV2-AIF1 Gene Therapy Brain : a Journal of Neurology. Jan, 2012 | Pubmed ID: 22120150 CRB1 Mutations in Inherited Retinal Dystrophies Human Mutation. Feb, 2012 | Pubmed ID: 22065545 RP1 and Autosomal Dominant Rod-cone Dystrophy: Novel Mutations, a Review of Published Variants, and Genotype-phenotype Correlation Human Mutation. Jan, 2012 | Pubmed ID: 22052604 Time-dependent Histopathological Changes Induced in Tilapia (Oreochromis Niloticus) After Acute Exposure to Pure Cylindrospermopsin by Oral and Intraperitoneal Route Ecotoxicology and Environmental Safety. Feb, 2012 | Pubmed ID: 22019311 A Regulatory Domain is Required for Foxn4 Activity During Retinogenesis Journal of Molecular Neuroscience : MN. Feb, 2012 | Pubmed ID: 21701787 ℮-conome: an Automated Tissue Counting Platform of Cone Photoreceptors for Rodent Models of Retinitis Pigmentosa BMC Ophthalmology. 2011 | Pubmed ID: 22185426 Transcriptomic Analysis of Human Retinal Detachment Reveals Both Inflammatory Response and Photoreceptor Death PloS One. 2011 | Pubmed ID: 22174898 Reevaluation of Dystrophin Localization in the Mouse Retina Investigative Ophthalmology & Visual Science. 2011 | Pubmed ID: 21896869 CYFIP Dependent Actin Remodeling Controls Specific Aspects of Drosophila Eye Morphogenesis Developmental Biology. Nov, 2011 | Pubmed ID: 21884694 Foveal Shape and Structure in a Normal Population Investigative Ophthalmology & Visual Science. Jul, 2011 | Pubmed ID: 21803966 A Novel DFNB31 Mutation Associated with Usher Type 2 Syndrome Showing Variable Degrees of Auditory Loss in a Consanguineous Portuguese Family Molecular Vision. 2011 | Pubmed ID: 21738389 Real-time Polymerase Chain Reaction and Intraocular Antibody Production for the Diagnosis of Viral Versus Toxoplasmic Infectious Posterior Uveitis Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Dec, 2011 | Pubmed ID: 21732111 Flat Choroidal Nevus Inaccessible to Ultrasound Sonography Evaluated by Enhanced Depth Imaging Optical Coherence Tomography Case Reports in Ophthalmology. May, 2011 | Pubmed ID: 21720534 Oxidative Stress Responses in Tilapia (Oreochromis Niloticus) Exposed to a Single Dose of Pure Cylindrospermopsin Under Laboratory Conditions: Influence of Exposure Route and Time of Sacrifice Aquatic Toxicology (Amsterdam, Netherlands). Sep, 2011 | Pubmed ID: 21703978 Acute Effects of Pure Cylindrospermopsin on the Activity and Transcription of Antioxidant Enzymes in Tilapia (Oreochromis Niloticus) Exposed by Gavage Ecotoxicology (London, England). Nov, 2011 | Pubmed ID: 21695509 Influence of Carboxylic Acid Functionalization on the Cytotoxic Effects Induced by Single Wall Carbon Nanotubes on Human Endothelial Cells (HUVEC) Toxicology in Vitro : an International Journal Published in Association with BIBRA. Dec, 2011 | Pubmed ID: 21651974 Outer Retinal Cysts in Age-related Macular Degeneration Acta Ophthalmologica. Sep, 2011 | Pubmed ID: 21631905 Quality Versus Quantity: Assessing Individual Research Performance Science Translational Medicine. May, 2011 | Pubmed ID: 21613620 Spotlight on Childhood Blindness The Journal of Clinical Investigation. Jun, 2011 | Pubmed ID: 21606601 Toxicity and Glutathione Implication in the Effects Observed by Exposure of the Liver Fish Cell Line PLHC-1 to Pure Cylindrospermopsin Ecotoxicology and Environmental Safety. Sep, 2011 | Pubmed ID: 21570723 Complete Exon Sequencing of All Known Usher Syndrome Genes Greatly Improves Molecular Diagnosis Orphanet Journal of Rare Diseases. 2011 | Pubmed ID: 21569298 Subretinal Lymphomatous Infiltration in Primary Intraocular Lymphoma Revealed by Optical Coherence Tomography Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Sep, 2011 | Pubmed ID: 21509532 Novel C2orf71 Mutations Account for ∼1% of Cases in a Large French ArRP Cohort Human Mutation. Apr, 2011 | Pubmed ID: 21412943 Topography of Patchy Retinal Whitening During Acute Perfused Retinal Vein Occlusion by Optical Coherence Tomography and Adaptive Optics Fundus Imaging European Journal of Ophthalmology. Sep-Oct, 2011 | Pubmed ID: 21360483 Foveal Damage in Habitual Poppers Users Archives of Ophthalmology. Jun, 2011 | Pubmed ID: 21320953 Subchronic Effects of Cyanobacterial Cells on the Transcription of Antioxidant Enzyme Genes in Tilapia (Oreochromis Niloticus) Ecotoxicology (London, England). Mar, 2011 | Pubmed ID: 21279735 Gene Therapy in Ophthalmology: Validation on Cultured Retinal Cells and Explants from Postmortem Human Eyes Human Gene Therapy. May, 2011 | Pubmed ID: 21142470 Mammalian Retinal Horizontal Cells Are Unconventional GABAergic Neurons Journal of Neurochemistry. Feb, 2011 | Pubmed ID: 21091475 Interaction Study Between RtPA and Bevacizumab The British Journal of Ophthalmology. May, 2011 | Pubmed ID: 20870640 Mitochondrial Medicine: to a New Era of Gene Therapy for Mitochondrial DNA Mutations Journal of Inherited Metabolic Disease. Apr, 2011 | Pubmed ID: 20571866 Fungal Keratitis in France Acta Ophthalmologica. Mar, 2011 | Pubmed ID: 20529076 Cellular-resolution in Vivo Imaging of the Feline Retina Using Adaptive Optics: Preliminary Results Veterinary Ophthalmology. Nov, 2010 | Pubmed ID: 21182721 Transplantation of Photoreceptor and Total Neural Retina Preserves Cone Function in P23H Rhodopsin Transgenic Rat PloS One. 2010 | Pubmed ID: 20976047 Expression of Rod-derived Cone Viability Factor: Dual Role of CRX in Regulating Promoter Activity and Cell-type Specificity PloS One. 2010 | Pubmed ID: 20949100 Poppers-associated Retinal Toxicity The New England Journal of Medicine. Oct, 2010 | Pubmed ID: 20942681 Prevalence and Novelty of PRPF31 Mutations in French Autosomal Dominant Rod-cone Dystrophy Patients and a Review of Published Reports BMC Medical Genetics. 2010 | Pubmed ID: 20939871 An Unusual Retinal Phenotype Associated with a Novel Mutation in RHO Archives of Ophthalmology. Aug, 2010 | Pubmed ID: 20697005 In Vitro Evaluation of Cytotoxicity and Genotoxicity of a Commercial Titanium Alloy for Dental Implantology Mutation Research. Sep, 2010 | Pubmed ID: 20615479 In Vivo Observation of the Locomotion of Microglial Cells in the Retina Glia. Nov, 2010 | Pubmed ID: 20578032 Targeting the Kallikrein-kinin System As a New Therapeutic Approach to Diabetic Retinopathy Current Opinion in Investigational Drugs (London, England : 2000). May, 2010 | Pubmed ID: 20419596 Rod-derived Cone Viability Factor for Treating Blinding Diseases: from Clinic to Redox Signaling Science Translational Medicine. Apr, 2010 | Pubmed ID: 20375363 [TRPM1, a New Gene Implicated in Congenital Stationary Night Blindness] Médecine Sciences : M/S. Mar, 2010 | Pubmed ID: 20346272 EYS is a Major Gene for Rod-cone Dystrophies in France Human Mutation. May, 2010 | Pubmed ID: 20333770 Spectrum of Rhodopsin Mutations in French Autosomal Dominant Rod-cone Dystrophy Patients Investigative Ophthalmology & Visual Science. Jul, 2010 | Pubmed ID: 20164459 Microcystin-LR Induces Toxic Effects in Differentiated and Undifferentiated Caco-2 Cells Archives of Toxicology. May, 2010 | Pubmed ID: 20112101 Cytomegalovirus Retinitis Associated with Good's Syndrome European Journal of Ophthalmology. Mar-Apr, 2010 | Pubmed ID: 19882506 The Homeobox Gene CHX10/VSX2 Regulates RdCVF Promoter Activity in the Inner Retina Human Molecular Genetics. Jan, 2010 | Pubmed ID: 19843539 Differential Oxidative Stress Responses to Pure Microcystin-LR and Microcystin-containing and Non-containing Cyanobacterial Crude Extracts on Caco-2 Cells Toxicon : Official Journal of the International Society on Toxinology. Feb-Mar, 2010 | Pubmed ID: 19825385 Imaging of Macroaneurysms Occurring During Retinal Vein Occlusion and Diabetic Retinopathy by Indocyanine Green Angiography and High Resolution Optical Coherence Tomography Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Feb, 2010 | Pubmed ID: 19701812 TRPM1 is Mutated in Patients with Autosomal-recessive Complete Congenital Stationary Night Blindness American Journal of Human Genetics. Nov, 2009 | Pubmed ID: 19896113 Functional Implication of Dp71 in Osmoregulation and Vascular Permeability of the Retina PloS One. 2009 | Pubmed ID: 19809515 Oxidative Stress Induced by Microcystin-LR on PLHC-1 Fish Cell Line Toxicology in Vitro : an International Journal Published in Association with BIBRA. Dec, 2009 | Pubmed ID: 19720136 Cytotoxicity of Carboxylic Acid Functionalized Single Wall Carbon Nanotubes on the Human Intestinal Cell Line Caco-2 Toxicology in Vitro : an International Journal Published in Association with BIBRA. Dec, 2009 | Pubmed ID: 19591917 Genotyping Microarray for CSNB-associated Genes Investigative Ophthalmology & Visual Science. Dec, 2009 | Pubmed ID: 19578023 The Antioxidant Glutathione in the Fish Cell Lines EPC and BCF-2: Response to Model Pro-oxidants As Measured by Three Different Fluorescent Dyes Toxicology in Vitro : an International Journal Published in Association with BIBRA. Apr, 2009 | Pubmed ID: 19444932 The Thioredoxin-like Protein Rod-derived Cone Viability Factor (RdCVFL) Interacts with TAU and Inhibits Its Phosphorylation in the Retina Molecular & Cellular Proteomics : MCP. Jun, 2009 | Pubmed ID: 19279044 Functional Cone Rescue by RdCVF Protein in a Dominant Model of Retinitis Pigmentosa Molecular Therapy : the Journal of the American Society of Gene Therapy. May, 2009 | Pubmed ID: 19277021 Identification of Anastomosis Between the Central Retinal Artery and the Central Retinal Vein in a Case of Central Retinal Vein Occlusion Due to Arteriovenous Malformation Retinal Cases & Brief Reports. 2008 | Pubmed ID: 25390603 Optimized Allotopic Expression of the Human Mitochondrial ND4 Prevents Blindness in a Rat Model of Mitochondrial Dysfunction American Journal of Human Genetics. Sep, 2008 | Pubmed ID: 18771762 The Optimized Allotopic Expression of ND1 or ND4 Genes Restores Respiratory Chain Complex I Activity in Fibroblasts Harboring Mutations in These Genes Biochimica Et Biophysica Acta. Oct, 2008 | Pubmed ID: 18513491 Association Between Visual Acuity and Medical and Non-medical Costs in Patients with Wet Age-related Macular Degeneration in France, Germany and Italy Drugs & Aging. 2008 | Pubmed ID: 18331076 [mRNA Localization to the Mitochondrial Surface: a Tool to Treat Retinal Pathologies Due to Mitochondrial DNA Mutations] Journal De La Société De Biologie. 2007 | Pubmed ID: 17762826 Health-related Quality of Life and Utility in Patients with Age-related Macular Degeneration Archives of Ophthalmology. Jul, 2007 | Pubmed ID: 17620576 Panretinal, High-resolution Color Photography of the Mouse Fundus Investigative Ophthalmology & Visual Science. Jun, 2007 | Pubmed ID: 17525211 Allotopic MRNA Localization to the Mitochondrial Surface Rescues Respiratory Chain Defects in Fibroblasts Harboring Mitochondrial DNA Mutations Affecting Complex I or V Subunits Rejuvenation Research. Jun, 2007 | Pubmed ID: 17518546 The Loss of Transcriptional Inhibition by the Photoreceptor-cell Specific Nuclear Receptor (NR2E3) is Not a Necessary Cause of Enhanced S-cone Syndrome Molecular Vision. 2007 | Pubmed ID: 17438525 Retinal Degenerations: from Cell Signaling to Cell Therapy; Pre-clinical and Clinical Issues Current Gene Therapy. Apr, 2007 | Pubmed ID: 17430131 Anxiety and Depression Prevalence Rates in Age-related Macular Degeneration Investigative Ophthalmology & Visual Science. Apr, 2007 | Pubmed ID: 17389477 [Retinal Repair by Transplantation of Photoreceptor Precursors] Médecine Sciences : M/S. Mar, 2007 | Pubmed ID: 17349277 Use of Suppression Subtractive Hybridization to Identify Genes Regulated by Ciliary Neurotrophic Factor in Postnatal Retinal Explants Molecular Vision. 2007 | Pubmed ID: 17327826 Disease-associated Variants of the Rod-derived Cone Viability Factor (RdCVF) in Leber Congenital Amaurosis. Rod-derived Cone Viability Variants in LCA Advances in Experimental Medicine and Biology. 2006 | Pubmed ID: 17249548 The Glutamate Transporter EAAT5 Works As a Presynaptic Receptor in Mouse Rod Bipolar Cells The Journal of Physiology. Nov, 2006 | Pubmed ID: 16973698 Involvement of Pleiotrophin in CNTF-mediated Differentiation of the Late Retinal Progenitor Cells Developmental Biology. Oct, 2006 | Pubmed ID: 16914133 PromAn: an Integrated Knowledge-based Web Server Dedicated to Promoter Analysis Nucleic Acids Research. Jul, 2006 | Pubmed ID: 16845074 Cone Dysfunction As a Paraneoplastic Syndrome Associated with Retinal Antigens Approximating 40 KiloDalton Ophthalmic Genetics. Jun, 2006 | Pubmed ID: 16754207 MRNA Localization to the Mitochondrial Surface Allows the Efficient Translocation Inside the Organelle of a Nuclear Recoded ATP6 Protein RNA (New York, N.Y.). Jul, 2006 | Pubmed ID: 16751614 High Resolution Fundus Imaging by Confocal Scanning Laser Ophthalmoscopy in the Mouse Vision Research. Apr, 2006 | Pubmed ID: 16289196 Saving Cone Cells in Hereditary Rod Diseases: a Possible Role for Rod-derived Cone Viability Factor (RdCVF) Therapy Retina (Philadelphia, Pa.). Dec, 2005 | Pubmed ID: 16374327 Optical Coherence Tomography Findings in Tamoxifen Retinopathy American Journal of Ophthalmology. Oct, 2005 | Pubmed ID: 16226541 Evidence for Glutamate-mediated Excitotoxic Mechanisms During Photoreceptor Degeneration in the Rd1 Mouse Retina Molecular Vision. 2005 | Pubmed ID: 16163266 Does GDNF Exert Its Neuroprotective Effects on Photoreceptors in the Rd1 Retina Through the Glial Glutamate Transporter GLAST? Molecular Vision. 2005 | Pubmed ID: 16163265 Rhodopsin Maturation Defects Induce Photoreceptor Death by Apoptosis: a Fly Model for RhodopsinPro23His Human Retinitis Pigmentosa Human Molecular Genetics. Sep, 2005 | Pubmed ID: 16049034 Retinal-cell-conditioned Medium Prevents TNF-alpha-induced Apoptosis of Purified Ganglion Cells Investigative Ophthalmology & Visual Science. Aug, 2005 | Pubmed ID: 16043875 The Sarcoglycan-sarcospan Complex Localization in Mouse Retina is Independent from Dystrophins Neuroscience Research. Sep, 2005 | Pubmed ID: 15993965 Molecular Cloning and Protein Expression of Duchenne Muscular Dystrophy Gene Products in Porcine Retina Neuromuscular Disorders : NMD. Jul, 2005 | Pubmed ID: 15941659 Role of Hyaluronidase in Diplopia After Peribulbar Anesthesia for Cataract Surgery Ophthalmology. May, 2005 | Pubmed ID: 15878070 [Neuroprotection of Photoreceptor Cells in Rod-cone Dystrophies: from Cell Therapy to Cell Signalling] Comptes Rendus Biologies. Feb, 2005 | Pubmed ID: 15771002 [Rod-derived Cone Viability Factor: a Clue for Therapy of Retinitis Pigmentosa?] Médecine Sciences : M/S. Jan, 2005 | Pubmed ID: 15639013 Identification of Gene Expression Changes Associated with the Progression of Retinal Degeneration in the Rd1 Mouse Investigative Ophthalmology & Visual Science. Sep, 2004 | Pubmed ID: 15326104 Identification and Characterization of Rod-derived Cone Viability Factor Nature Genetics. Jul, 2004 | Pubmed ID: 15220920 Inherited Retinal Degenerations: Therapeutic Prospects Biology of the Cell / Under the Auspices of the European Cell Biology Organization. May, 2004 | Pubmed ID: 15145530 The Search for Rod-dependent Cone Viability Factors, Secreted Factors Promoting Cone Viability Novartis Foundation Symposium. 2004 | Pubmed ID: 14750600 The Aging of the Retina Experimental Gerontology. Aug, 2003 | Pubmed ID: 12915204 Differential Proteomic Analysis of the Mouse Retina: the Induction of Crystallin Proteins by Retinal Degeneration in the Rd1 Mouse Molecular & Cellular Proteomics : MCP. Aug, 2003 | Pubmed ID: 12832458 [Retinitis Pigmentosa: Pathogenic Progress and Therapeutic Hopes] La Revue Du Praticien. Oct, 2002 | Pubmed ID: 12564163 Prenatal Human Ocular Degeneration Occurs in Leber's Congenital Amaurosis (LCA2) The Journal of Gene Medicine. Jul-Aug, 2002 | Pubmed ID: 12124981 Cellular Localization of the Vesicular Inhibitory Amino Acid Transporter in the Mouse and Human Retina The Journal of Comparative Neurology. Jul, 2002 | Pubmed ID: 12115694 Kegle-beriget kulturer fra nethinden af kyllingembryoner til at studere Rod til Cone Cellular Interaktioner Géraldine Millet-Puel1, Myriam Pinault1, Marie Cordonnier1, Valérie Fontaine1, José-Alain Sahel1, Thierry Léveillard1 1Department of Genetics - Sorbonne Université, INSERM, CNRS, Institut de la Vision JoVE 61998 Neurosciences Definerede Xeno-fri og Feeder-fri kultur betingelser for den Generation af menneskelige iPSC-afledte Retinal Cell modeller Amélie Slembrouck-Brec*1, Céline Nanteau*1, José-Alain Sahel1, Olivier Goureau1, Sacha Reichman1 1Institut de la Vision, Sorbonne Université, INSERM, CNRS, F-75012 Paris, France JoVE 57795 Biologie du développement Brug Adenoassocieret virus som værktøj til at studere Retinale Barrierer i Disease Ophélie Vacca1,2,3, Brahim El Mathari1,2,3, Marie Darche1,2,3, José-Alain Sahel1,2,3, Alvaro Rendon1,2,3, Deniz Dalkara1,2,3 1Department of Therapeutics, Institut de la Vision, Sorbonne Universtés, UPMC Univ Paris 06, UMR_S 968, 2INSERM, U968, 3CNRS, UMR_7210 Médecine Vibratome Sektionsinddeling Mouse Retina Forbered fotoreceptoren kulturer Emmanuelle Clérin1,4,5,6, Ying Yang1,4,5,6, Valérie Forster2,4,5,6, Valérie Fontaine3,4,5,6, José-Alain Sahel4,5,6, Thierry Léveillard1,4,5,6 1Department of Genetics, UMR_S 968, Institut de la Vision, 2Department of Visual Information, UMR_S 968, Institut de la Vision, 3Exploratory Team, UMR_S 968, Institut de la Vision, 4Sorbonne Universités, Paris 06, UMR_S 968, Institut de la Vision, 5INSERM, U968, Institut de la Vision, 6CNRS, UMR_7210, Institut de la Vision JoVE 51954 Neurosciences Transkriptom analyse af menneskets retinale kirurgiske prøver vha. Journal Marie-Noëlle Delyfer1,2,3,4, Najate Aït-Ali1,2,3, Hawa Camara1,2,3, Emmanuelle Clérin1,2,3, Jean-François Korobelnik4, José-Alain Sahel1,2,3, Thierry Léveillard1,2,3 1U968, Institut National de la Santé et de la Recherche Médicale, 2UMR S 968, Université Pierre et Marie Curie, 3UMR 7210, Centre National de la Recherche Scientifique, 4Départment d'Ophtalmologie, Centre Hospitalier Universitaire de Bordeaux JoVE 50375 Médecine
Kegle-beriget kulturer fra nethinden af kyllingembryoner til at studere Rod til Cone Cellular Interaktioner Géraldine Millet-Puel1, Myriam Pinault1, Marie Cordonnier1, Valérie Fontaine1, José-Alain Sahel1, Thierry Léveillard1 1Department of Genetics - Sorbonne Université, INSERM, CNRS, Institut de la Vision JoVE 61998 Neurosciences
Definerede Xeno-fri og Feeder-fri kultur betingelser for den Generation af menneskelige iPSC-afledte Retinal Cell modeller Amélie Slembrouck-Brec*1, Céline Nanteau*1, José-Alain Sahel1, Olivier Goureau1, Sacha Reichman1 1Institut de la Vision, Sorbonne Université, INSERM, CNRS, F-75012 Paris, France JoVE 57795 Biologie du développement
Brug Adenoassocieret virus som værktøj til at studere Retinale Barrierer i Disease Ophélie Vacca1,2,3, Brahim El Mathari1,2,3, Marie Darche1,2,3, José-Alain Sahel1,2,3, Alvaro Rendon1,2,3, Deniz Dalkara1,2,3 1Department of Therapeutics, Institut de la Vision, Sorbonne Universtés, UPMC Univ Paris 06, UMR_S 968, 2INSERM, U968, 3CNRS, UMR_7210 Médecine
Vibratome Sektionsinddeling Mouse Retina Forbered fotoreceptoren kulturer Emmanuelle Clérin1,4,5,6, Ying Yang1,4,5,6, Valérie Forster2,4,5,6, Valérie Fontaine3,4,5,6, José-Alain Sahel4,5,6, Thierry Léveillard1,4,5,6 1Department of Genetics, UMR_S 968, Institut de la Vision, 2Department of Visual Information, UMR_S 968, Institut de la Vision, 3Exploratory Team, UMR_S 968, Institut de la Vision, 4Sorbonne Universités, Paris 06, UMR_S 968, Institut de la Vision, 5INSERM, U968, Institut de la Vision, 6CNRS, UMR_7210, Institut de la Vision JoVE 51954 Neurosciences
Transkriptom analyse af menneskets retinale kirurgiske prøver vha. Journal Marie-Noëlle Delyfer1,2,3,4, Najate Aït-Ali1,2,3, Hawa Camara1,2,3, Emmanuelle Clérin1,2,3, Jean-François Korobelnik4, José-Alain Sahel1,2,3, Thierry Léveillard1,2,3 1U968, Institut National de la Santé et de la Recherche Médicale, 2UMR S 968, Université Pierre et Marie Curie, 3UMR 7210, Centre National de la Recherche Scientifique, 4Départment d'Ophtalmologie, Centre Hospitalier Universitaire de Bordeaux JoVE 50375 Médecine