Kathy Steece-Collier Department of Translational Neuroscience, College of Human Medicine Michigan State University Biography Publications Institution JoVE Articles Kathy Steece-Collier has not added a biography. If you are Kathy Steece-Collier and would like to personalize this page please email our Author Liaison for assistance. Publications α-Synuclein Antisense Oligonucleotides As a Disease-modifying Therapy for Parkinson's Disease JCI Insight. 03, 2021 | Pubmed ID: 33682798 Striatal Afferent BDNF is Disrupted by Synucleinopathy and Partially Restored by STN DBS The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2021 | Pubmed ID: 33472823 The BDNF Val66Met Polymorphism (rs6265) Enhances Dopamine Neuron Graft Efficacy and Side-effect Liability in Rs6265 Knock-in Rats Neurobiology of Disease. Jan, 2021 | Pubmed ID: 33188920 Preclinical Evidence in Support of Repurposing Sub-anesthetic Ketamine As a Treatment for L-DOPA-induced Dyskinesia Experimental Neurology. 11, 2020 | Pubmed ID: 32717354 Striatal Nurr1, but Not FosB Expression Links a Levodopa-induced Dyskinesia Phenotype to Genotype in Fisher 344 Vs. Lewis Hemiparkinsonian Rats Experimental Neurology. 08, 2020 | Pubmed ID: 32387398 Striatal Nurr1 Facilitates the Dyskinetic State and Exacerbates Levodopa-Induced Dyskinesia in a Rat Model of Parkinson's Disease The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 04, 2020 | Pubmed ID: 32238479 Cell Therapy for Parkinson's Disease: Why It Doesn't Work Every Time Movement Disorders : Official Journal of the Movement Disorder Society. 08, 2019 | Pubmed ID: 31234239 Genetic Silencing of Striatal CaV1.3 Prevents and Ameliorates Levodopa Dyskinesia Movement Disorders : Official Journal of the Movement Disorder Society. 05, 2019 | Pubmed ID: 31002755 Regulation of Dopamine Neurotransmission from Serotonergic Neurons by Ectopic Expression of the Dopamine D2 Autoreceptor Blocks Levodopa-induced Dyskinesia Acta Neuropathologica Communications. 01, 2019 | Pubmed ID: 30646956 Subthalamic Nucleus Deep Brain Stimulation Does Not Modify the Functional Deficits or Axonopathy Induced by Nigrostriatal α-Synuclein Overexpression Scientific Reports. Nov, 2017 | Pubmed ID: 29180681 Subthalamic Nucleus Deep Brain Stimulation Employs TrkB Signaling for Neuroprotection and Functional Restoration The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 07, 2017 | Pubmed ID: 28607168 Repairing the Aged Parkinsonian Striatum: Lessons from the Lab and Clinic Journal of Clinical & Cellular Immunology. Dec, 2016 | Pubmed ID: 28111608 Impact of Age and Vector Construct on Striatal and Nigral Transgene Expression Molecular Therapy. Methods & Clinical Development. 2016 | Pubmed ID: 27933309 Loss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and L-Dopa-Mediated Dyskinesias in a Model of Parkinson's Disease The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2015 | Pubmed ID: 26558771 Sonic Hedgehog Controls the Phenotypic Fate and Therapeutic Efficacy of Grafted Neural Precursor Cells in a Model of Nigrostriatal Neurodegeneration PloS One. 2015 | Pubmed ID: 26340267 High-Frequency Stimulation of the Rat Entopeduncular Nucleus Does Not Provide Functional or Morphological Neuroprotection from 6-Hydroxydopamine PloS One. 2015 | Pubmed ID: 26222442 Pathophysiology of L-dopa-induced Motor and Non-motor Complications in Parkinson's Disease Progress in Neurobiology. Sep, 2015 | Pubmed ID: 26209473 Intrastriatal Injection of Pre-formed Mouse α-synuclein Fibrils into Rats Triggers α-synuclein Pathology and Bilateral Nigrostriatal Degeneration Neurobiology of Disease. Oct, 2015 | Pubmed ID: 26093169 The Longitudinal Transcriptomic Response of the Substantia Nigra to Intrastriatal 6-hydroxydopamine Reveals Significant Upregulation of Regeneration-associated Genes PloS One. 2015 | Pubmed ID: 25992874 Interrogating the Aged Striatum: Robust Survival of Grafted Dopamine Neurons in Aging Rats Produces Inferior Behavioral Recovery and Evidence of Impaired Integration Neurobiology of Disease. May, 2015 | Pubmed ID: 25771169 Recombinant Adenoassociated Virus 2/5-mediated Gene Transfer is Reduced in the Aged Rat Midbrain Neurobiology of Aging. Feb, 2015 | Pubmed ID: 25457558 Chronic Amitriptyline Treatment Attenuates Nigrostriatal Degeneration and Significantly Alters Trophic Support in a Rat Model of Parkinsonism Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Mar, 2015 | Pubmed ID: 25267343 Aberrant Restoration of Spines and Their Synapses in L-DOPA-induced Dyskinesia: Involvement of Corticostriatal but Not Thalamostriatal Synapses The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2013 | Pubmed ID: 23843533 Advances in Thin Tissue Golgi-Cox Impregnation: Fast, Reliable Methods for Multi-assay Analyses in Rodent and Non-human Primate Brain Journal of Neuroscience Methods. Mar, 2013 | Pubmed ID: 23313849 Anatomy of Graft-induced Dyskinesias: Circuit Remodeling in the Parkinsonian Striatum Basal Ganglia. Mar, 2012 | Pubmed ID: 22712056 Subthalamic Nucleus Stimulation Increases Brain Derived Neurotrophic Factor in the Nigrostriatal System and Primary Motor Cortex Journal of Parkinson's Disease. May, 2011 | Pubmed ID: 22328911 Striatal Pleiotrophin Overexpression Provides Functional and Morphological Neuroprotection in the 6-Hydroxydopamine Model Molecular Therapy : the Journal of the American Society of Gene Therapy. Oct, 2011 | Pubmed ID: 22008908 Transfer of Host-derived α Synuclein to Grafted Dopaminergic Neurons in Rat Neurobiology of Disease. Sep, 2011 | Pubmed ID: 21600984 تحريض وتقييم خلل الحركة الناجم عن ليفودوبا في نموذج الفئران لمرض باركنسون Margaret E. Caulfield1, Jennifer A. Stancati1, Kathy Steece-Collier1,2 1Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 2Hauenstein Neuroscience Center, Mercy Health Saint Mary's JoVE 62970 Neurosciences
تحريض وتقييم خلل الحركة الناجم عن ليفودوبا في نموذج الفئران لمرض باركنسون Margaret E. Caulfield1, Jennifer A. Stancati1, Kathy Steece-Collier1,2 1Department of Translational Neuroscience, College of Human Medicine, Michigan State University, 2Hauenstein Neuroscience Center, Mercy Health Saint Mary's JoVE 62970 Neurosciences