Mario J. Borgnia Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute National Institutes of Health Biography Publications Institution JoVE Articles Mario J. Borgnia has not added a biography. If you are Mario J. Borgnia and would like to personalize this page please email our Author Liaison for assistance. Publications Computational Separation of Conformational Heterogeneity Using Cryo-electron Tomography and 3D Sub-volume Averaging Journal of Structural Biology. Jan, 2012 | Pubmed ID: 22248450 Three-dimensional Structures of Soluble CD4-bound States of Trimeric Simian Immunodeficiency Virus Envelope Glycoproteins Determined by Using Cryo-electron Tomography Journal of Virology. Dec, 2011 | Pubmed ID: 21937655 Trimeric HIV-1 Glycoprotein Gp140 Immunogens and Native HIV-1 Envelope Glycoproteins Display the Same Closed and Open Quaternary Molecular Architectures Proceedings of the National Academy of Sciences of the United States of America. Jul, 2011 | Pubmed ID: 21709254 Lateral Density of Receptor Arrays in the Membrane Plane Influences Sensitivity of the E. Coli Chemotaxis Response The EMBO Journal. May, 2011 | Pubmed ID: 21441899 Molecular Architectures of Trimeric SIV and HIV-1 Envelope Glycoproteins on Intact Viruses: Strain-dependent Variation in Quaternary Structure PLoS Pathogens. 2010 | Pubmed ID: 21203482 Molecular Architecture of Native HIV-1 Gp120 Trimers Nature. Sep, 2008 | Pubmed ID: 18668044 Evaluation of Denoising Algorithms for Biological Electron Tomography Journal of Structural Biology. Oct, 2008 | Pubmed ID: 18585059 Three-dimensional Imaging of the Highly Bent Architecture of Bdellovibrio Bacteriovorus by Using Cryo-electron Tomography Journal of Bacteriology. Apr, 2008 | Pubmed ID: 18203829 Molecular Structure of a 9-MDa Icosahedral Pyruvate Dehydrogenase Subcomplex Containing the E2 and E3 Enzymes Using Cryoelectron Microscopy The Journal of Biological Chemistry. Feb, 2006 | Pubmed ID: 16308322 Visualization of Alpha-helical Features in a Density Map Constructed Using 9 Molecular Images of the 1.8 MDa Icosahedral Core of Pyruvate Dehydrogenase Journal of Structural Biology. Aug, 2004 | Pubmed ID: 15193642 Automated Image Acquisition and Processing Using a New Generation of 4K X 4K CCD Cameras for Cryo Electron Microscopic Studies of Macromolecular Assemblies Journal of Structural Biology. Aug, 2003 | Pubmed ID: 12972350 A Core-weighted Fitting Method for Docking Atomic Structures into Low-resolution Maps: Application to Cryo-electron Microscopy Journal of Structural Biology. Jan, 2003 | Pubmed ID: 12576021 Determination of Molecular Structures of HIV Envelope Glycoproteins using Cryo-Electron Tomography and Automated Sub-tomogram Averaging Joel R. Meyerson1,2, Tommi A. White1, Donald Bliss3, Amy Moran3, Alberto Bartesaghi1, Mario J. Borgnia1, M. Jason V. de la Cruz1, David Schauder1, Lisa M. Hartnell1, Rachna Nandwani1,4, Moez Dawood5, Brianna Kim6, Jun Hong Kim7, John Sununu8, Lisa Yang9, Siddhant Bhatia10, Carolyn Subramaniam1, Darrell E. Hurt11, Laurent Gaudreault12, Sriram Subramaniam1 1Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 2The Medical Research Council Mitochondrial Biology Unit, University of Cambridge, 3National Library of Medicine, National Institutes of Health, 4Massachusetts Institute of Technology, 5William Fremd High School, 6University of Virginia, 7Duke University, 8Yale University, 9University of Notre Dame, 10Washington University in St. Louis, 11Bioinformatics and Computational Biosciences Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 12Thomas Jefferson High School for Science and Technology JoVE 2770 Immunologie et Infection
Determination of Molecular Structures of HIV Envelope Glycoproteins using Cryo-Electron Tomography and Automated Sub-tomogram Averaging Joel R. Meyerson1,2, Tommi A. White1, Donald Bliss3, Amy Moran3, Alberto Bartesaghi1, Mario J. Borgnia1, M. Jason V. de la Cruz1, David Schauder1, Lisa M. Hartnell1, Rachna Nandwani1,4, Moez Dawood5, Brianna Kim6, Jun Hong Kim7, John Sununu8, Lisa Yang9, Siddhant Bhatia10, Carolyn Subramaniam1, Darrell E. Hurt11, Laurent Gaudreault12, Sriram Subramaniam1 1Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 2The Medical Research Council Mitochondrial Biology Unit, University of Cambridge, 3National Library of Medicine, National Institutes of Health, 4Massachusetts Institute of Technology, 5William Fremd High School, 6University of Virginia, 7Duke University, 8Yale University, 9University of Notre Dame, 10Washington University in St. Louis, 11Bioinformatics and Computational Biosciences Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 12Thomas Jefferson High School for Science and Technology JoVE 2770 Immunologie et Infection