Matthew McKenzie Centre for Genetic Diseases Hudson Institute of Medical Research Biography Publications Institution JoVE Articles Matthew McKenzie has not added a biography. If you are Matthew McKenzie and would like to personalize this page please email our Author Liaison for assistance. Publications Monocytes and Dendritic Cells Are the Primary Sources of Interleukin 37 in Human Immune Cells Journal of Leukocyte Biology. Nov, 2016 | Pubmed ID: 27881605 Tim29 is a Novel Subunit of the Human TIM22 Translocase and is Involved in Complex Assembly and Stability ELife. Aug, 2016 | Pubmed ID: 27554484 Correction: AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation PloS One. 2016 | Pubmed ID: 27442024 Proof-of-Concept of Polymeric Sol-Gels in Multi-Drug Delivery and Intraoperative Image-Guided Surgery for Peritoneal Ovarian Cancer Pharmaceutical Research. Sep, 2016 | Pubmed ID: 27283829 Impaired Cellular Bioenergetics Causes Mitochondrial Calcium Handling Defects in MT-ND5 Mutant Cybrids PloS One. 2016 | Pubmed ID: 27110715 Restoration of Normal Embryogenesis by Mitochondrial Supplementation in Pig Oocytes Exhibiting Mitochondrial DNA Deficiency Scientific Reports. Mar, 2016 | Pubmed ID: 26987907 Vitamin D3 Therapy in Patients with Asthma Complicated by Sinonasal Disease: Secondary Analysis of the Vitamin D Add-on Therapy Enhances Corticosteroid Responsiveness in Asthma Trial The Journal of Allergy and Clinical Immunology. Aug, 2016 | Pubmed ID: 26971692 Loss of Mitochondrial DNA-encoded Protein ND1 Results in Disruption of Complex I Biogenesis During Early Stages of Assembly FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2016 | Pubmed ID: 26929434 AarF Domain Containing Kinase 3 (ADCK3) Mutant Cells Display Signs of Oxidative Stress, Defects in Mitochondrial Homeostasis and Lysosomal Accumulation PloS One. 2016 | Pubmed ID: 26866375 Combined Defects in Oxidative Phosphorylation and Fatty Acid β-oxidation in Mitochondrial Disease Bioscience Reports. Feb, 2016 | Pubmed ID: 26839416 Deletion of the Complex I Subunit NDUFS4 Adversely Modulates Cellular Differentiation Stem Cells and Development. Feb, 2016 | Pubmed ID: 26608563 Dietary Interventions Designed to Protect the Perinatal Brain from Hypoxic-ischemic Encephalopathy--Creatine Prophylaxis and the Need for Multi-organ Protection Neurochemistry International. May, 2016 | Pubmed ID: 26576837 Generation of Xenomitochondrial Embryonic Stem Cells for the Production of Live Xenomitochondrial Mice Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26530681 Conservation Implications of Omitting Historical Data Sources: Response to Baisre Conservation Biology : the Journal of the Society for Conservation Biology. Feb, 2016 | Pubmed ID: 26524216 Analysis of Mitochondrial DNA in Induced Pluripotent and Embryonic Stem Cells Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 26621601 Hydrogel-Based Drug Delivery Systems for Poorly Water-Soluble Drugs Molecules (Basel, Switzerland). Nov, 2015 | Pubmed ID: 26580588 Anti-cancer Analogues ME-143 and ME-344 Exert Toxicity by Directly Inhibiting Mitochondrial NADH: Ubiquinone Oxidoreductase (Complex I) American Journal of Cancer Research. 2015 | Pubmed ID: 25973307 Characterization of Mitochondrial FOXRED1 in the Assembly of Respiratory Chain Complex I Human Molecular Genetics. May, 2015 | Pubmed ID: 25678554 Capture of Somatic MtDNA Point Mutations with Severe Effects on Oxidative Phosphorylation in Synaptosome Cybrid Clones from Human Brain Human Mutation. Dec, 2014 | Pubmed ID: 25219341 Critical Review of Bronchial Thermoplasty: Where Should It Fit into Asthma Therapy? Current Allergy and Asthma Reports. Nov, 2014 | Pubmed ID: 25189294 Effects of Empiric Antifungal Therapy for Septic Shock on Time to Appropriate Therapy for Candida Infection: a Pilot Study Clinical Therapeutics. Sep, 2014 | Pubmed ID: 25064625 Mitochondrial Research in Australia: a Major Player in Worldwide Trends Biochimica Et Biophysica Acta. Apr, 2014 | Pubmed ID: 24468066 A Founder Mutation in PET100 Causes Isolated Complex IV Deficiency in Lebanese Individuals with Leigh Syndrome American Journal of Human Genetics. Feb, 2014 | Pubmed ID: 24462369 The Identification of Mitochondrial DNA Variants in Glioblastoma Multiforme Acta Neuropathologica Communications. Jan, 2014 | Pubmed ID: 24383468 Fluid Balance and Cardiac Function in Septic Shock As Predictors of Hospital Mortality Critical Care (London, England). Oct, 2013 | Pubmed ID: 24138869 Clostridium Difficile Infection: a Multicenter Study of Epidemiology and Outcomes in Mechanically Ventilated Patients Critical Care Medicine. Aug, 2013 | Pubmed ID: 23863229 Modulation of Ceramide-induced Cell Death and Superoxide Production by Mitochondrial DNA-encoded Respiratory Chain Defects in Rattus Xenocybrid Mouse Cells Biochimica Et Biophysica Acta. Jul, 2013 | Pubmed ID: 23567871 Mitochondrial DNA Haplotypes Define Gene Expression Patterns in Pluripotent and Differentiating Embryonic Stem Cells Stem Cells (Dayton, Ohio). Apr, 2013 | Pubmed ID: 23307500 Mitochondrial Dysfunction in a Novel Form of Autosomal Recessive Ataxia Mitochondrion. May, 2013 | Pubmed ID: 23178371 The Effects of Nuclear Reprogramming on Mitochondrial DNA Replication Stem Cell Reviews. Feb, 2013 | Pubmed ID: 21994000 Mitochondrial DNA Copy Number is Regulated in a Tissue Specific Manner by DNA Methylation of the Nuclear-encoded DNA Polymerase Gamma A Nucleic Acids Research. Nov, 2012 | Pubmed ID: 22941637 Proteomic and Metabolomic Analyses of Mitochondrial Complex I-deficient Mouse Model Generated by Spontaneous B2 Short Interspersed Nuclear Element (SINE) Insertion into NADH Dehydrogenase (ubiquinone) Fe-S Protein 4 (Ndufs4) Gene The Journal of Biological Chemistry. Jun, 2012 | Pubmed ID: 22535952 Next-generation Sequencing in Molecular Diagnosis: NUBPL Mutations Highlight the Challenges of Variant Detection and Interpretation Human Mutation. Feb, 2012 | Pubmed ID: 22072591 Understanding Mitochondrial Complex I Assembly in Health and Disease Biochimica Et Biophysica Acta. Jun, 2012 | Pubmed ID: 21924235 Timely Attention to Staffing Nursing. Dec, 2011 | Pubmed ID: 22195306 Mutations in the Gene Encoding C8orf38 Block Complex I Assembly by Inhibiting Production of the Mitochondria-encoded Subunit ND1 Journal of Molecular Biology. Dec, 2011 | Pubmed ID: 22019594 Mutations in MTFMT Underlie a Human Disorder of Formylation Causing Impaired Mitochondrial Translation Cell Metabolism. Sep, 2011 | Pubmed ID: 21907147 Mutation of the Mitochondrial Tyrosyl-tRNA Synthetase Gene, YARS2, Causes Myopathy, Lactic Acidosis, and Sideroblastic Anemia--MLASA Syndrome American Journal of Human Genetics. Jul, 2010 | Pubmed ID: 20598274 Assembly Factors of Human Mitochondrial Complex I and Their Defects in Disease IUBMB Life. Jul, 2010 | Pubmed ID: 20552642 Mitochondrial Cardiolipin Involved in Outer-membrane Protein Biogenesis: Implications for Barth Syndrome Current Biology : CB. Dec, 2009 | Pubmed ID: 19962311 Assembly of Nuclear DNA-encoded Subunits into Mitochondrial Complex IV, and Their Preferential Integration into Supercomplex Forms in Patient Mitochondria The FEBS Journal. Nov, 2009 | Pubmed ID: 19843159 Chapter 18 Analysis of Respiratory Chain Complex Assembly with Radiolabeled Nuclear- and Mitochondrial-encoded Subunits Methods in Enzymology. 2009 | Pubmed ID: 19348897 Assembly of Mitochondrial Complex I and Defects in Disease Biochimica Et Biophysica Acta. Jan, 2009 | Pubmed ID: 18501715 Mutation of C20orf7 Disrupts Complex I Assembly and Causes Lethal Neonatal Mitochondrial Disease American Journal of Human Genetics. Oct, 2008 | Pubmed ID: 18940309 Mitochondrial ND5 Gene Variation Associated with Encephalomyopathy and Mitochondrial ATP Consumption The Journal of Biological Chemistry. Dec, 2007 | Pubmed ID: 17940288 Analysis of the Assembly Profiles for Mitochondrial- and Nuclear-DNA-encoded Subunits into Complex I Molecular and Cellular Biology. Jun, 2007 | Pubmed ID: 17438127 Analysis of Mitochondrial Subunit Assembly into Respiratory Chain Complexes Using Blue Native Polyacrylamide Gel Electrophoresis Analytical Biochemistry. May, 2007 | Pubmed ID: 17391635 Probing the Nucleation Mechanism for the Binary N-nonane/1-alcohol Series with Atomistic Simulations The Journal of Physical Chemistry. B. Sep, 2006 | Pubmed ID: 16970491 Mitochondrial Respiratory Chain Supercomplexes Are Destabilized in Barth Syndrome Patients Journal of Molecular Biology. Aug, 2006 | Pubmed ID: 16857210 Unravelling the Peculiar Nucleation Mechanisms for Non-ideal Binary Mixtures with Atomistic Simulations The Journal of Physical Chemistry. B. Mar, 2006 | Pubmed ID: 16494406 Mitochondrial Disease: Mutations and Mechanisms Neurochemical Research. Mar, 2004 | Pubmed ID: 15038606 Production of Homoplasmic Xenomitochondrial Mice Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14745024 Functional Respiratory Chain Analyses in Murid Xenomitochondrial Cybrids Expose Coevolutionary Constraints of Cytochrome B and Nuclear Subunits of Complex III Molecular Biology and Evolution. Jul, 2003 | Pubmed ID: 12777531 Comparison of Log P Values Obtained from CAChe and Other Sources Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering. Mar, 2003 | Pubmed ID: 12680579 Samtidig måling af Mitokondriel Calcium og mitokondriemembranen Potentiale i levende celler ved Fluorescent Microscopy Matthew McKenzie1,2, Sze C. Lim1, Michael R. Duchen3 1Centre for Genetic Diseases, Hudson Institute of Medical Research, 2The Department of Molecular and Translational Sciences, Monash University, 3Department of Physiology, University College London JoVE 55166 Biologie
Samtidig måling af Mitokondriel Calcium og mitokondriemembranen Potentiale i levende celler ved Fluorescent Microscopy Matthew McKenzie1,2, Sze C. Lim1, Michael R. Duchen3 1Centre for Genetic Diseases, Hudson Institute of Medical Research, 2The Department of Molecular and Translational Sciences, Monash University, 3Department of Physiology, University College London JoVE 55166 Biologie