Michael J. Iadarola Neurobiology and Pain Therapeutics Section National Institute of Dental and Craniofacial Research, National Institutes of Health Biography Publications Institution JoVE Articles Michael J. Iadarola has not added a biography. If you are Michael J. Iadarola and would like to personalize this page please email our Author Liaison for assistance. Publications Small Molecule Positive Allosteric Modulation of TRPV1 Activation by Vanilloids and Acidic PH The Journal of Pharmacology and Experimental Therapeutics. Jan, 2012 | Pubmed ID: 22005042 Serological Studies Confirm the Novel Astrovirus HMOAstV-C As a Highly Prevalent Human Infectious Agent PloS One. 2011 | Pubmed ID: 21829634 Microfluidic LIPS for Serum Antibody Detection: Demonstration of a Rapid Test for HSV-2 Infection Biomedical Microdevices. Dec, 2011 | Pubmed ID: 21826483 Antibody Profiling of Borrelia Burgdorferi Infection in Horses Clinical and Vaccine Immunology : CVI. Sep, 2011 | Pubmed ID: 21775514 Resveratrol Inhibits Cdk5 Activity Through Regulation of P35 Expression Molecular Pain. 2011 | Pubmed ID: 21736731 Searching for Biomarkers: Humoral Response Profiling with Luciferase Immunoprecipitation Systems Expert Review of Proteomics. Jun, 2011 | Pubmed ID: 21679112 The Vanilloid Agonist Resiniferatoxin for Interventional-based Pain Control Current Topics in Medicinal Chemistry. 2011 | Pubmed ID: 21671877 Emerging Tactical Strategies for Fighting the War on Cancer Based on the Genetic Landscape American Journal of Translational Research. May, 2011 | Pubmed ID: 21654880 LIPS Arrays for Simultaneous Detection of Antibodies Against Partial and Whole Proteomes of HCV, HIV and EBV Molecular BioSystems. May, 2011 | Pubmed ID: 21336381 Recombinant Expression of the AChR-alpha1 Subunit for the Detection of Conformation-dependent Epitopes in Myasthenia Gravis Neuromuscular Disorders : NMD. Mar, 2011 | Pubmed ID: 21195619 Ablation of Rat TRPV1-expressing Adelta/C-fibers with Resiniferatoxin: Analysis of Withdrawal Behaviors, Recovery of Function and Molecular Correlates Molecular Pain. 2010 | Pubmed ID: 21167052 Rapid Induction of Autoantibodies During ARDS and Septic Shock Journal of Translational Medicine. 2010 | Pubmed ID: 20946647 Synthetic Biology for Translational Research American Journal of Translational Research. 2010 | Pubmed ID: 20733948 Anti-cytokine Autoantibodies Are Associated with Opportunistic Infection in Patients with Thymic Neoplasia Blood. Dec, 2010 | Pubmed ID: 20716769 Proteome-wide Anti-hepatitis C Virus (HCV) and Anti-HIV Antibody Profiling for Predicting and Monitoring the Response to HCV Therapy in HIV-coinfected Patients The Journal of Infectious Diseases. Sep, 2010 | Pubmed ID: 20684729 Antibody-profiling Technologies for Studying Humoral Responses to Infectious Agents Expert Review of Vaccines. Jun, 2010 | Pubmed ID: 20518713 Distinct Profiles of Antibodies to Kaposi Sarcoma-associated Herpesvirus Antigens in Patients with Kaposi Sarcoma, Multicentric Castleman Disease, and Primary Effusion Lymphoma The Journal of Infectious Diseases. Jun, 2010 | Pubmed ID: 20443737 Extraordinary Antigenicity of the Human Ro52 Autoantigen American Journal of Translational Research. 2010 | Pubmed ID: 20407604 Prolonged Analgesic Response of Cornea to Topical Resiniferatoxin, a Potent TRPV1 Agonist Pain. Jun, 2010 | Pubmed ID: 20403666 Rapid, Simple, Quantitative, and Highly Sensitive Antibody Detection for Lyme Disease Clinical and Vaccine Immunology : CVI. Jun, 2010 | Pubmed ID: 20392886 RT-PCR Analysis of Pain Genes: Use of Gel-based RT-PCR for Studying Induced and Tissue-enriched Gene Expression Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20336429 High Levels of Anti-GAD65 and Anti-Ro52 Autoantibodies in a Patient with Major Depressive Disorder Showing Psychomotor Disturbance Journal of Neuroimmunology. May, 2010 | Pubmed ID: 20227114 Comparison of Radioimmunoprecipitation with Luciferase Immunoprecipitation for Autoantibodies to GAD65 and IA-2beta Diabetes Care. Apr, 2010 | Pubmed ID: 20086252 Rapid Serological Detection of Autoantibodies Associated with Sjögren's Syndrome Journal of Translational Medicine. 2009 | Pubmed ID: 19778440 Cytokine Gene Expression After Total Hip Arthroplasty: Surgical Site Versus Circulating Neutrophil Response Anesthesia and Analgesia. Sep, 2009 | Pubmed ID: 19690273 Sensitive and Robust Luminescent Profiling of Anti-La and Other Autoantibodies in Sjogren's Syndrome Autoimmunity. Sep, 2009 | Pubmed ID: 19657778 A Four-antigen Mixture for Rapid Assessment of Onchocerca Volvulus Infection PLoS Neglected Tropical Diseases. 2009 | Pubmed ID: 19436728 Highly Quantitative Serological Detection of Anti-cytomegalovirus (CMV) Antibodies Virology Journal. 2009 | Pubmed ID: 19409090 Four-antigen Mixture Containing V-cyclin for Serological Screening of Human Herpesvirus 8 Infection Clinical and Vaccine Immunology : CVI. May, 2009 | Pubmed ID: 19261774 Serological Diagnosis of Human Herpes Simplex Virus Type 1 and 2 Infections by Luciferase Immunoprecipitation System Assay Clinical and Vaccine Immunology : CVI. Mar, 2009 | Pubmed ID: 19129469 Tumor Necrosis Factor-alpha Regulates Cyclin-dependent Kinase 5 Activity During Pain Signaling Through Transcriptional Activation of P35 The Journal of Biological Chemistry. Jan, 2009 | Pubmed ID: 19049962 Anti-HTLV Antibody Profiling Reveals an Antibody Signature for HTLV-I-associated Myelopathy/tropical Spastic Paraparesis (HAM/TSP) Retrovirology. 2008 | Pubmed ID: 18937847 Structure-activity Relationships of 1,4-dihydropyridines That Act As Enhancers of the Vanilloid Receptor 1 (TRPV1) Bioorganic & Medicinal Chemistry. Oct, 2008 | Pubmed ID: 18809334 A Luciferase Immunoprecipitation Systems Assay Enhances the Sensitivity and Specificity of Diagnosis of Strongyloides Stercoralis Infection The Journal of Infectious Diseases. Aug, 2008 | Pubmed ID: 18558872 A New Luminescence Assay for Autoantibodies to Mammalian Cell-prepared Insulinoma-associated Protein 2 Diabetes Care. Sep, 2008 | Pubmed ID: 18535195 Rapid, Novel, Specific, High-throughput Assay for Diagnosis of Loa Loa Infection Journal of Clinical Microbiology. Jul, 2008 | Pubmed ID: 18508942 Perineural Resiniferatoxin Selectively Inhibits Inflammatory Hyperalgesia Molecular Pain. 2008 | Pubmed ID: 18199335 Localization of S100A8 and S100A9 Expressing Neutrophils to Spinal Cord During Peripheral Tissue Inflammation Pain. Jan, 2008 | Pubmed ID: 18063312 High Definition Profiling of Autoantibodies to Glutamic Acid Decarboxylases GAD65/GAD67 in Stiff-person Syndrome Biochemical and Biophysical Research Communications. Feb, 2008 | Pubmed ID: 18047830 Modulatory Role of Neuropeptide FF System in Nociception and Opiate Analgesia Neuropeptides. Feb, 2008 | Pubmed ID: 17854890 Complete Pain Relief: Potential Problems and Diagnostic Solutions Nature Clinical Practice. Neurology. Dec, 2007 | Pubmed ID: 17984990 Peripheral Inflammation Increases Scya2 Expression in Sensory Ganglia and Cytokine and Endothelial Related Gene Expression in Inflamed Tissue Journal of Neurochemistry. Nov, 2007 | Pubmed ID: 17883394 Cyclin-dependent Kinase 5 Modulates Nociceptive Signaling Through Direct Phosphorylation of Transient Receptor Potential Vanilloid 1 Proceedings of the National Academy of Sciences of the United States of America. Jan, 2007 | Pubmed ID: 17194758 Modulatory Roles of the NPFF System in Pain Mechanisms at the Spinal Level Peptides. May, 2006 | Pubmed ID: 16443306 Cyclin-dependent Kinase 5 Activity Regulates Pain Signaling Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006 | Pubmed ID: 16407116 Physiologic and Antinociceptive Effects of Intrathecal Resiniferatoxin in a Canine Bone Cancer Model Anesthesiology. Nov, 2005 | Pubmed ID: 16249680 Spinal Cord NR1 Serine Phosphorylation and NR2B Subunit Suppression Following Peripheral Inflammation Molecular Pain. 2005 | Pubmed ID: 16137337 Peripheral Targeting of the Trigeminal Ganglion Via the Infraorbital Foramen As a Therapeutic Strategy Brain Research. Brain Research Protocols. Sep, 2005 | Pubmed ID: 16024266 Increased Activity of Cyclin-dependent Kinase 5 Leads to Attenuation of Cocaine-mediated Dopamine Signaling Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15665076 Comparison of Experimental and Acute Clinical Pain Responses in Humans As Pain Phenotypes The Journal of Pain : Official Journal of the American Pain Society. Sep, 2004 | Pubmed ID: 15501195 Genetic Influence on Variability in Human Acute Experimental Pain Sensitivity Associated with Gender, Ethnicity and Psychological Temperament Pain. Jun, 2004 | Pubmed ID: 15157710 Deletion of Vanilloid Receptor 1-expressing Primary Afferent Neurons for Pain Control The Journal of Clinical Investigation. May, 2004 | Pubmed ID: 15124026 Vanilloid Receptor 1 Regulates Multiple Calcium Compartments and Contributes to Ca2+-induced Ca2+ Release in Sensory Neurons The Journal of Biological Chemistry. Apr, 2004 | Pubmed ID: 14963041 Resiniferatoxin-induced Loss of Plasma Membrane in Vanilloid Receptor Expressing Cells Neurotoxicology. Dec, 2003 | Pubmed ID: 14637384 Peripherally Induced Resiniferatoxin Analgesia Pain. Jul, 2003 | Pubmed ID: 12855332 Direct Interstitial Infusion of NK1-targeted Neurotoxin into the Spinal Cord: a Computational Model American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Jul, 2003 | Pubmed ID: 12793999 Cystatin C As a Cerebrospinal Fluid Biomarker for Pain in Humans Pain. Apr, 2003 | Pubmed ID: 12670666 Reproducibility of Pain Measurement and Pain Perception Pain. Jul, 2002 | Pubmed ID: 12098633 Protein Kinase C(alpha) is Required for Vanilloid Receptor 1 Activation. Evidence for Multiple Signaling Pathways The Journal of Biological Chemistry. Sep, 2002 | Pubmed ID: 12095983 Antibody Profiling by Luciferase Immunoprecipitation Systems (LIPS) Peter D. Burbelo1, Kathryn H. Ching1, Caitlin M. Klimavicz1, Michael J. Iadarola1 1Neurobiology and Pain Therapeutics Section, National Institute of Dental and Craniofacial Research, National Institutes of Health JoVE 1549 Biologie
Antibody Profiling by Luciferase Immunoprecipitation Systems (LIPS) Peter D. Burbelo1, Kathryn H. Ching1, Caitlin M. Klimavicz1, Michael J. Iadarola1 1Neurobiology and Pain Therapeutics Section, National Institute of Dental and Craniofacial Research, National Institutes of Health JoVE 1549 Biologie