Olivier De Wever Department of Radiation Oncology and Experimental Cancer Research University of Ghent Biography Publications Institution JoVE Articles Olivier De Wever has not added a biography. If you are Olivier De Wever and would like to personalize this page please email our Author Liaison for assistance. Publications Impact of Neoadjuvant Therapy on Cancer-associated Fibroblasts in Rectal Cancer Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. May, 2015 | Pubmed ID: 26021554 Combined Targeting of EGFR/HER Promotes Anti-tumor Efficacy in Subsets of KRAS Mutant Lung Cancer Resistant to Single EGFR Blockade Oncotarget. May, 2015 | Pubmed ID: 25992771 Biological Properties of Extracellular Vesicles and Their Physiological Functions Journal of Extracellular Vesicles. 2015 | Pubmed ID: 25979354 Tumor-environment Biomimetics Delay Peritoneal Metastasis Formation by Deceiving and Redirecting Disseminated Cancer Cells Biomaterials. Jun, 2015 | Pubmed ID: 25907048 Cancer-associated Fibroblasts Connect Metastasis-promoting Communication in Colorectal Cancer Frontiers in Oncology. 2015 | Pubmed ID: 25853091 Fibroblast-induced Matrix Remodeling Paves the Path for Invasion Cell Cycle (Georgetown, Tex.). 2015 | Pubmed ID: 25790091 The Quorum Sensing Peptides PhrG, CSP and EDF Promote Angiogenesis and Invasion of Breast Cancer Cells in Vitro PloS One. 2015 | Pubmed ID: 25780927 Crosstalk Between the Microbiome and Cancer Cells by Quorum Sensing Peptides Peptides. Feb, 2015 | Pubmed ID: 25559405 An Open Data Ecosystem for Cell Migration Research Trends in Cell Biology. Feb, 2015 | Pubmed ID: 25484346 Differential Regulation of Extracellular Matrix Protein Expression in Carcinoma-associated Fibroblasts by TGF-β1 Regulates Cancer Cell Spreading but Not Adhesion Oncoscience. 2014 | Pubmed ID: 25593993 Expression Profiling of Migrated and Invaded Breast Cancer Cells Predicts Early Metastatic Relapse and Reveals Krüppel-like Factor 9 As a Potential Suppressor of Invasive Growth in Breast Cancer Oncoscience. 2014 | Pubmed ID: 25593984 Modifications of Cell Signalling and Redox Balance by Targeting Protein Acetylation Using Natural and Engineered Molecules: Implications in Cancer Therapy Current Topics in Medicinal Chemistry. 2014 | Pubmed ID: 25478886 The Impact of Disparate Isolation Methods for Extracellular Vesicles on Downstream RNA Profiling Journal of Extracellular Vesicles. 2014 | Pubmed ID: 25317274 Cancer-associated Adipose Tissue Promotes Breast Cancer Progression by Paracrine Oncostatin M and Jak/STAT3 Signaling Cancer Research. Dec, 2014 | Pubmed ID: 25252914 Activation of EGFR, HER2 and HER3 by Neurotensin/neurotensin Receptor 1 Renders Breast Tumors Aggressive Yet Highly Responsive to Lapatinib and Metformin in Mice Oncotarget. Sep, 2014 | Pubmed ID: 25249538 Histopathological Characterization of Ductal Carcinoma in Situ (DCIS) of the Breast According to HER2 Amplification Status and Molecular Subtype Virchows Archiv : an International Journal of Pathology. Sep, 2014 | Pubmed ID: 24973889 Bone Marrow Stromal Cell-derived Exosomes As Communicators in Drug Resistance in Multiple Myeloma Cells Blood. Jul, 2014 | Pubmed ID: 24928860 Krüppel-like Factors in Cancer Progression: Three Fingers on the Steering Wheel Oncotarget. Jan, 2014 | Pubmed ID: 24429391 Carcinoma-associated Fibroblasts Provide Operational Flexibility in Metastasis Seminars in Cancer Biology. Apr, 2014 | Pubmed ID: 24406210 Mesenchymal Stem Cell Secreted Platelet Derived Growth Factor Exerts a Pro-migratory Effect on Resident Cardiac Atrial Appendage Stem Cells Journal of Molecular and Cellular Cardiology. Jan, 2014 | Pubmed ID: 24326234 Single Cell and Spheroid Collagen Type I Invasion Assay Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24092429 A Nanobody Targeting the F-actin Capping Protein CapG Restrains Breast Cancer Metastasis Breast Cancer Research : BCR. 2013 | Pubmed ID: 24330716 Tenascin-C Downregulates Wnt Inhibitor Dickkopf-1, Promoting Tumorigenesis in a Neuroendocrine Tumor Model Cell Reports. Oct, 2013 | Pubmed ID: 24139798 Stromal Architecture and Periductal Decorin Are Potential Prognostic Markers for Ipsilateral Locoregional Recurrence in Ductal Carcinoma in Situ of the Breast Histopathology. Oct, 2013 | Pubmed ID: 23889174 Radiation-induced Myosin IIA Expression Stimulates Collagen Type I Matrix Reorganization Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Jun, 2013 | Pubmed ID: 23742963 Targeted Liposome-Loaded Microbubbles for Cell-Specific Ultrasound-Triggered Drug Delivery Small (Weinheim an Der Bergstrasse, Germany). Jun, 2013 | Pubmed ID: 23737360 Rab27 GTPases Distribute Extracellular Nanomaps for Invasive Growth and Metastasis: Implications for Prognosis and Treatment International Journal of Molecular Sciences. 2013 | Pubmed ID: 23665896 MiR-145 Overexpression Suppresses the Migration and Invasion of Metastatic Melanoma Cells International Journal of Oncology. Apr, 2013 | Pubmed ID: 23404256 Vacuolar H+ ATPase Expression and Activity is Required for Rab27B-dependent Invasive Growth and Metastasis of Breast Cancer International Journal of Cancer. Journal International Du Cancer. Aug, 2013 | Pubmed ID: 23390068 Frondoside a Suppressive Effects on Lung Cancer Survival, Tumor Growth, Angiogenesis, Invasion, and Metastasis PloS One. 2013 | Pubmed ID: 23308143 Differential Secretome Analysis of Cancer-associated Fibroblasts and Bone Marrow-derived Precursors to Identify Microenvironmental Regulators of Colon Cancer Progression Proteomics. Jan, 2013 | Pubmed ID: 23175172 Bone Marrow-derived Mesenchymal Stem Cells Promote Colorectal Cancer Progression Through Paracrine Neuregulin 1/HER3 Signalling Gut. Apr, 2013 | Pubmed ID: 22535374 Comparative Analysis of Dynamic Cell Viability, Migration and Invasion Assessments by Novel Real-time Technology and Classic Endpoint Assays PloS One. 2012 | Pubmed ID: 23094027 Tumor Grafts Derived from Sarcoma Patients Retain Tumor Morphology, Viability, and Invasion Potential and Indicate Disease Outcomes in the Chick Chorioallantoic Membrane Model Cancer Letters. Dec, 2012 | Pubmed ID: 22841668 An Immunohistochemical Analysis of Rab27B Distribution in Fetal and Adult Tissue The International Journal of Developmental Biology. 2012 | Pubmed ID: 22811270 Identification of a GαGβγ, AKT and PKCα Signalome Associated with Invasive Growth in Two Genetic Models of Human Breast Cancer Cell Epithelial-to-mesenchymal Transition International Journal of Oncology. Jul, 2012 | Pubmed ID: 22552300 Recent Developments in Myofibroblast Biology: Paradigms for Connective Tissue Remodeling The American Journal of Pathology. Apr, 2012 | Pubmed ID: 22387320 Engineered 3D Microporous Gelatin Scaffolds to Study Cell Migration Chemical Communications (Cambridge, England). Apr, 2012 | Pubmed ID: 22378164 The Role of Non-muscle Myosin IIA in Aggregation and Invasion of Human MCF-7 Breast Cancer Cells The International Journal of Developmental Biology. 2011 | Pubmed ID: 22161839 Developmental and Cancer Research on the Mammary Gland Nowadays The International Journal of Developmental Biology. 2011 | Pubmed ID: 22161823 Use of Tamoxifen Before and During Pregnancy The Oncologist. 2011 | Pubmed ID: 22020212 Role of the Focal Adhesion Protein Kindlin-1 in Breast Cancer Growth and Lung Metastasis Journal of the National Cancer Institute. Sep, 2011 | Pubmed ID: 21832234 The Tumor Ecosystem Regulates the Roads for Invasion and Metastasis Clinics and Research in Hepatology and Gastroenterology. Nov, 2011 | Pubmed ID: 21676670 Priming and Potentiation of DNA Damage Response by Fibronectin in Human Colon Cancer Cells and Tumor-derived Myofibroblasts International Journal of Oncology. Aug, 2011 | Pubmed ID: 21567080 CCN5, a Novel Transcriptional Repressor of the Transforming Growth Factor β Signaling Pathway Molecular and Cellular Biology. Apr, 2011 | Pubmed ID: 21262769 The Secretory Small GTPase Rab27B As a Marker for Breast Cancer Progression Oncotarget. Aug, 2010 | Pubmed ID: 21304180 An Ex(o)citing Machinery for Invasive Tumor Growth Cancer Research. Dec, 2010 | Pubmed ID: 21098711 P-cadherin Counteracts Myosin II-B Function: Implications in Melanoma Progression Molecular Cancer. 2010 | Pubmed ID: 20860798 Implication of Metastasis Suppressor NM23-H1 in Maintaining Adherens Junctions and Limiting the Invasive Potential of Human Cancer Cells Cancer Research. Oct, 2010 | Pubmed ID: 20841469 Effect of the Secretory Small GTPase Rab27B on Breast Cancer Growth, Invasion, and Metastasis Journal of the National Cancer Institute. Jun, 2010 | Pubmed ID: 20484105 Resident and Bone Marrow-derived Mesenchymal Stem Cells in Head and Neck Squamous Cell Carcinoma Oral Oncology. May, 2010 | Pubmed ID: 20219413 Direct Effects of Delta Opioid Receptor Agonists on Invasion-associated Activities of HCT-8/E11 Colon Cancer Cells Anticancer Research. Jan, 2010 | Pubmed ID: 20150612 Modeling and Quantification of Cancer Cell Invasion Through Collagen Type I Matrices The International Journal of Developmental Biology. 2010 | Pubmed ID: 19757378 Inhibition of Heterotrimeric G Protein Signaling by a Small Molecule Acting on Galpha Subunit The Journal of Biological Chemistry. Oct, 2009 | Pubmed ID: 19648112 The Extracellular Matrix Regulates Cancer Progression and Therapy Response: Implications for Prognosis and Treatment Current Pharmaceutical Design. 2009 | Pubmed ID: 19355975 Netrin-1 Induces Apoptosis in Human Cervical Tumor Cells Via the TAp73alpha Tumor Suppressor Cancer Research. Oct, 2008 | Pubmed ID: 18922894 The Transforming Functions of PI3-kinase-gamma Are Linked to Disruption of Intercellular Adhesion and Promotion of Cancer Cell Invasion Annals of the New York Academy of Sciences. Sep, 2008 | Pubmed ID: 18837901 Stromal Myofibroblasts Are Drivers of Invasive Cancer Growth International Journal of Cancer. Journal International Du Cancer. Nov, 2008 | Pubmed ID: 18777559 Molecular Signature and Therapeutic Perspective of the Epithelial-to-mesenchymal Transitions in Epithelial Cancers Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. Aug-Oct, 2008 | Pubmed ID: 18718806 Molecular and Pathological Signatures of Epithelial-mesenchymal Transitions at the Cancer Invasion Front Histochemistry and Cell Biology. Sep, 2008 | Pubmed ID: 18648847 Differential Impact of TGF-beta and EGF on Fibroblast Differentiation and Invasion Reciprocally Promotes Colon Cancer Cell Invasion Cancer Letters. Aug, 2008 | Pubmed ID: 18423981 A Novel Missense Mutation (G43S) in the Switch I Region of Rab27A Causing Griscelli Syndrome Molecular Genetics and Metabolism. Jun, 2008 | Pubmed ID: 18397837 Role of WISP-2/CCN5 in the Maintenance of a Differentiated and Noninvasive Phenotype in Human Breast Cancer Cells Molecular and Cellular Biology. Feb, 2008 | Pubmed ID: 18070926 Activation of the FAK-src Molecular Scaffolds and P130Cas-JNK Signaling Cascades by Alpha1-integrins During Colon Cancer Cell Invasion International Journal of Oncology. Dec, 2007 | Pubmed ID: 17982677 Soluble Cadherins As Cancer Biomarkers Clinical & Experimental Metastasis. 2007 | Pubmed ID: 17952616 Estrogen Receptor Signaling is an Unstable Feature of the Gonadotropic LbetaT2 Cell Line Molecular and Cellular Endocrinology. Jul, 2007 | Pubmed ID: 17561339 Proinvasive Activity of BMP-7 Through SMAD4/src-independent and ERK/Rac/JNK-dependent Signaling Pathways in Colon Cancer Cells Cellular Signalling. Aug, 2007 | Pubmed ID: 17478078 Estrogen Receptor Alpha (ERalpha) and Insulin-like Growth Factor I Receptor (IGF-IR) Cross-talk in the Gonadotropic AlphaT3-1 Cell Line Journal of Cellular Physiology. Sep, 2007 | Pubmed ID: 17458895 The Tandem PDZ Domains of Syntenin Promote Cell Invasion Experimental Cell Research. May, 2007 | Pubmed ID: 17451681 Growth Factor Modulation of Fibroblast Proliferation, Differentiation, and Invasion: Implications for Tissue Valve Engineering Tissue Engineering. Oct, 2006 | Pubmed ID: 17518640 Soluble N-cadherin in Human Biological Fluids International Journal of Cancer. Journal International Du Cancer. Dec, 2006 | Pubmed ID: 16998833 Commutators of PAR-1 Signaling in Cancer Cell Invasion Reveal an Essential Role of the Rho-Rho Kinase Axis and Tumor Microenvironment Oncogene. Dec, 2005 | Pubmed ID: 16091733 The Proinvasive Activity of Wnt-2 is Mediated Through a Noncanonical Wnt Pathway Coupled to GSK-3beta and C-Jun/AP-1 Signaling FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2005 | Pubmed ID: 15507471 Mutated E-cadherin: Genomic and Functional Characterization in Thyroid Cells from the KAT Family Thyroid : Official Journal of the American Thyroid Association. Nov, 2004 | Pubmed ID: 15671768 Germinal Tumor Invasion and the Role of the Testicular Stroma The International Journal of Developmental Biology. 2004 | Pubmed ID: 15349829 Critical Role of N-cadherin in Myofibroblast Invasion and Migration in Vitro Stimulated by Colon-cancer-cell-derived TGF-beta or Wounding Journal of Cell Science. Sep, 2004 | Pubmed ID: 15331629 Disruption of STAT3 Signaling Leads to Tumor Cell Invasion Through Alterations of Homotypic Cell-cell Adhesion Complexes Oncogene. Apr, 2004 | Pubmed ID: 15077188 Tenascin-C and SF/HGF Produced by Myofibroblasts in Vitro Provide Convergent Pro-invasive Signals to Human Colon Cancer Cells Through RhoA and Rac FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2004 | Pubmed ID: 15059978 The Intracellular E-cadherin Germline Mutation V832 M Lacks the Ability to Mediate Cell-cell Adhesion and to Suppress Invasion Oncogene. Aug, 2003 | Pubmed ID: 12944922 Role of Tissue Stroma in Cancer Cell Invasion The Journal of Pathology. Jul, 2003 | Pubmed ID: 12845611 Requirement of Both Mucins and Proteoglycans in Cell-cell Dissociation and Invasiveness of Colon Carcinoma HT-29 Cells International Journal of Cancer. Journal International Du Cancer. May, 2003 | Pubmed ID: 12640674 Identification of CDH1 Germline Missense Mutations Associated with Functional Inactivation of the E-cadherin Protein in Young Gastric Cancer Probands Human Molecular Genetics. Mar, 2003 | Pubmed ID: 12588804 Invasion of Retinal Pigment Epithelial Cells: N-cadherin, Hepatocyte Growth Factor, and Focal Adhesion Kinase Investigative Ophthalmology & Visual Science. Feb, 2003 | Pubmed ID: 12556370 Role of Myofibroblasts at the Invasion Front Biological Chemistry. Jan, 2002 | Pubmed ID: 11928823 Chick Hjerte Invasion analyse for Teste Invasivitet av kreftceller og aktiviteten til Potensielt Anti-invasive Forbindelser Marc E. Bracke1, Bart I. Roman2, Christian V. Stevens2, Liselot M. Mus1, Virinder S. Parmar3, Olivier De Wever1, Marc M. Mareel1 1Department of Radiation Oncology and Experimental Cancer Research, University of Ghent, 2Department of Sustainable Organic Chemistry and Technology, University of Ghent, 3Department of Chemistry, University of Delhi JoVE 52792 Médecine Den Gwen M.L. Sys1, Lore Lapeire2, Nikita Stevens1, Herman Favoreel3, Ramses Forsyth4, Marc Bracke2, Olivier De Wever2 1Department of Orthopaedic Surgery and Traumatology, Ghent University Hospital, 2Department of Radiation Oncology and Experimental Cancer Research, Ghent University, 3Department of Virology, Parasitology, and Immunology, Ghent University, 4Pathlicon JoVE 50522 Médecine
Chick Hjerte Invasion analyse for Teste Invasivitet av kreftceller og aktiviteten til Potensielt Anti-invasive Forbindelser Marc E. Bracke1, Bart I. Roman2, Christian V. Stevens2, Liselot M. Mus1, Virinder S. Parmar3, Olivier De Wever1, Marc M. Mareel1 1Department of Radiation Oncology and Experimental Cancer Research, University of Ghent, 2Department of Sustainable Organic Chemistry and Technology, University of Ghent, 3Department of Chemistry, University of Delhi JoVE 52792 Médecine
Den Gwen M.L. Sys1, Lore Lapeire2, Nikita Stevens1, Herman Favoreel3, Ramses Forsyth4, Marc Bracke2, Olivier De Wever2 1Department of Orthopaedic Surgery and Traumatology, Ghent University Hospital, 2Department of Radiation Oncology and Experimental Cancer Research, Ghent University, 3Department of Virology, Parasitology, and Immunology, Ghent University, 4Pathlicon JoVE 50522 Médecine