Thomas Chuen Lam Centre for Myopia Research, School of Optometry The Hong Kong Polytechnic University Biography Publications Institution JoVE Articles Thomas Chuen Lam has not added a biography. If you are Thomas Chuen Lam and would like to personalize this page please email our Author Liaison for assistance. Publications A Review of Using Traditional Chinese Medicine in the Management of Glaucoma and Cataract Clinical & Experimental Optometry. Oct, 2023 | Pubmed ID: 37879342 Differential Responses of Retinal Neurons and Glia Revealed Via Proteomic Analysis on Primary and Secondary Retinal Ganglion Cell Degeneration International Journal of Molecular Sciences. Jul, 2023 | Pubmed ID: 37569482 Additive Effects of Narrowband Light and Optical Defocus on Chick Eye Growth and Refraction Eye and Vision (London, England). Apr, 2023 | Pubmed ID: 37004128 Proteomic Profiling Revealed Mitochondrial Dysfunction in Photoreceptor Cells Under Hyperglycemia International Journal of Molecular Sciences. Nov, 2022 | Pubmed ID: 36362154 Mechanistic Effects of Baicalein on Aqueous Humor Drainage and Intraocular Pressure International Journal of Molecular Sciences. Jul, 2022 | Pubmed ID: 35806375 Retinal Proteomic Analysis in a Mouse Model of Endotoxin-Induced Uveitis Using Data-Independent Acquisition-Based Mass Spectrometry International Journal of Molecular Sciences. Jun, 2022 | Pubmed ID: 35742911 Transcriptional Profiling of the Chick Retina Identifies Down-regulation of and Genes During Early Lens-induced Myopia Molecular Omics. Jun, 2022 | Pubmed ID: 35420081 Alteration of EIF2 Signaling, Glycolysis, and Dopamine Secretion in Form-Deprived Myopia in Response to 1% Atropine Treatment: Evidence From Interactive ITRAQ-MS and SWATH-MS Proteomics Using a Guinea Pig Model Frontiers in Pharmacology. 2022 | Pubmed ID: 35153787 Thrombospondin-1 Mediates Rho-kinase Inhibitor-induced Increase in Outflow-facility Journal of Cellular Physiology. Dec, 2021 | Pubmed ID: 34180057 Human Tear Proteome Dataset in Response to Daily Wear of Water Gradient Contact Lens Using SWATH-MS Approach Data in Brief. Jun, 2021 | Pubmed ID: 34095372 The Effect of Low-Dose Atropine on Alpha Ganglion Cell Signaling in the Mouse Retina Frontiers in Cellular Neuroscience. 2021 | Pubmed ID: 34025362 SWATH Based Quantitative Proteomics Reveals Significant Lipid Metabolism in Early Myopic Guinea Pig Retina International Journal of Molecular Sciences. Apr, 2021 | Pubmed ID: 33946922 Critical Role of Mass Spectrometry Proteomics in Tear Biomarker Discovery for Multifactorial Ocular Diseases (Review) International Journal of Molecular Medicine. May, 2021 | Pubmed ID: 33760148 Corneal Proteome and Differentially Expressed Corneal Proteins in Highly Myopic Chicks Using a Label-free SWATH-MS Quantification Approach Scientific Reports. Mar, 2021 | Pubmed ID: 33750851 High-pH Reversed-phase Fractionated Neural Retina Proteome of Normal Growing C57BL/6 Mouse Scientific Data. Jan, 2021 | Pubmed ID: 33500412 Combined Retinal Proteome Datasets in Response to Atropine Treatment Using ITRAQ and SWATH-MS Based Proteomics Approaches in Guinea Pig Myopia Model Data in Brief. Dec, 2020 | Pubmed ID: 33304948 Data on Differentially Expressed Proteins in Rock Inhibitor-treated Human Trabecular Meshwork Cells Using SWATH-based Proteomics Data in Brief. Aug, 2020 | Pubmed ID: 32613038 Data on Protein Changes of Chick Vitreous During Normal Eye Growth Using Data-independent Acquisition (SWATH-MS) Data in Brief. Jun, 2020 | Pubmed ID: 32373688 Data on Assessment of Safety and Tear Proteome Change in Response to Orthokeratology Lens - Insight from Integrating Clinical Data and Next Generation Proteomics Data in Brief. Apr, 2020 | Pubmed ID: 32071970 Alteration of Retinal Metabolism and Oxidative Stress May Implicate Myopic Eye Growth: Evidence from Discovery and Targeted Proteomics in an Animal Model Journal of Proteomics. Jun, 2020 | Pubmed ID: 32061809 Data on Corneal Proteome and Differentially Expressed Corneal Proteins in Highly Myopic Chicks Using a Data Independent Quantification Approach Data in Brief. Oct, 2019 | Pubmed ID: 31667243 Data on Differentially Expressed Proteins in Retinal Emmetropization Process in Guinea Pig Using Integrated SWATH-based and Targeted-based Proteomics Data in Brief. Dec, 2018 | Pubmed ID: 30505911 The Role of the RhoA/ROCK Signaling Pathway in Mechanical Strain-Induced Scleral Myofibroblast Differentiation Investigative Ophthalmology & Visual Science. Jul, 2018 | Pubmed ID: 30029249 The Interactions Between Bright Light and Competing Defocus During Emmetropization in Chicks Investigative Ophthalmology & Visual Science. Jun, 2018 | Pubmed ID: 30025112 Integrated SWATH-based and Targeted-based Proteomics Provide Insights into the Retinal Emmetropization Process in Guinea Pig Journal of Proteomics. Jun, 2018 | Pubmed ID: 29572162 Isotope-coded Protein Label Based Quantitative Proteomic Analysis Reveals Significant Up-regulation of Apolipoprotein A1 and Ovotransferrin in the Myopic Chick Vitreous Scientific Reports. Oct, 2017 | Pubmed ID: 28978931 New Insight of Common Regulatory Pathways in Human Trabecular Meshwork Cells in Response to Dexamethasone and Prednisolone Using an Integrated Quantitative Proteomics: SWATH and MRM-HR Mass Spectrometry Journal of Proteome Research. Oct, 2017 | Pubmed ID: 28920441 Post-translational Modifications and Their Applications in Eye Research (Review) Molecular Medicine Reports. Jun, 2017 | Pubmed ID: 28487982 Cyclic Adenosine Monophosphate Activates Retinal Apolipoprotein A1 Expression and Inhibits Myopic Eye Growth Investigative Ophthalmology & Visual Science. Dec, 2015 | Pubmed ID: 26720467 Advancing Tear Fluid Analysis Using a Standardized Protocol for Proteomics Research (Video) | JoVE Jimmy Sung-Hei Tse*1, Ying-Hon Sze*1,2, Jimmy Ka-Wai Cheung1,2, King-Kit Li1, Thomas Chuen Lam1,2,3,4 1Centre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, 2Centre for Eye and Vision Research (CEVR), 3Research Centre for SHARP Vision (RCSV), The Hong Kong Polytechnic University, 4Research Centre for Chinese Medicine Innovation (RCMI), The Hong Kong Polytechnic University JoVE 64617 Médecine
Advancing Tear Fluid Analysis Using a Standardized Protocol for Proteomics Research (Video) | JoVE Jimmy Sung-Hei Tse*1, Ying-Hon Sze*1,2, Jimmy Ka-Wai Cheung1,2, King-Kit Li1, Thomas Chuen Lam1,2,3,4 1Centre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, 2Centre for Eye and Vision Research (CEVR), 3Research Centre for SHARP Vision (RCSV), The Hong Kong Polytechnic University, 4Research Centre for Chinese Medicine Innovation (RCMI), The Hong Kong Polytechnic University JoVE 64617 Médecine