Uwe Groß Institut für Medizinische Mikrobiologie Universitätsmedizin Göttingen Biography Publications Institution JoVE Articles Uwe Groß has not added a biography. If you are Uwe Groß and would like to personalize this page please email our Author Liaison for assistance. Publications Association of Campylobacter Jejuni Ssp. Jejuni Chemotaxis Receptor Genes with Multilocus Sequence Types and Source of Isolation European Journal of Microbiology & Immunology. Sep, 2016 | Pubmed ID: 27766165 High Prevalence of Nontoxigenic Clostridium Difficile Isolated from Hospitalized and Non-hospitalized Individuals in Rural Ghana International Journal of Medical Microbiology : IJMM. Sep, 2016 | Pubmed ID: 27693000 Prevalence of Azole-resistant Aspergillus Fumigatus in the Environment of Thailand Medical Mycology. Sep, 2016 | Pubmed ID: 27664994 High Prevalence of Human Papillomaviruses in Ghanaian Pregnant Women Medical Microbiology and Immunology. Sep, 2016 | Pubmed ID: 27601062 Aspergillus Fumigatus Carrying TR34/L98H Resistance Allele Causing Complicated Suppurative Otitis Media in Tanzania: Call for Improved Diagnosis of Fungi in Sub-Saharan Africa BMC Infectious Diseases. Sep, 2016 | Pubmed ID: 27589956 Seroprevalence of Campylobacter-Specific Antibodies in Two German Duck Farms - A Prospective Follow-Up Study European Journal of Microbiology & Immunology. Jun, 2016 | Pubmed ID: 27429794 High Oral Carriage of Non-albicans Candida Spp. Among HIV-infected Individuals International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases. Aug, 2016 | Pubmed ID: 27401585 Erratum To: Serological Makers of Rubella Infection in Africa in the Pre Vaccination Era: a Systematic Review BMC Research Notes. Jul, 2016 | Pubmed ID: 27381216 Serological Evidence of Acute Rubella Infection Among Under-fives in Mwanza: a Threat to Increasing Rates of Congenital Rubella Syndrome in Tanzania Italian Journal of Pediatrics. May, 2016 | Pubmed ID: 27225802 Ruxolitinib Induces Interleukin 17 and Ameliorates Chronic Mucocutaneous Candidiasis Caused by STAT1 Gain-of-Function Mutation Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Apr, 2016 | Pubmed ID: 26787170 Towards Proteomic Species Barcoding of Fungi - An Example Using Scedosporium/Pseudallescheria Complex Isolates Fungal Biology. Feb, 2016 | Pubmed ID: 26781372 Aspergillus Oerlinghausenensis, a New Mould Species Closely Related to A. Fumigatus FEMS Microbiology Letters. Feb, 2016 | Pubmed ID: 26667219 Predictive Factors for Preterm Delivery Under Rural Conditions in Post-tsunami Banda Aceh Journal of Perinatal Medicine. Jul, 2016 | Pubmed ID: 25980381 SMRT Sequencing of the Campylobacter Coli BfR-CA-9557 Genome Sequence Reveals Unique Methylation Motifs BMC Genomics. Dec, 2015 | Pubmed ID: 26689587 Serological Makers of Rubella Infection in Africa in the Pre Vaccination Era: a Systematic Review BMC Research Notes. Nov, 2015 | Pubmed ID: 26602892 The Reduction in Antibiotic Use in Hospitals Deutsches Arzteblatt International. Oct, 2015 | Pubmed ID: 26554421 Molecular Types of Cryptococcus Gattii/Cryptococcus Neoformans Species Complex from Clinical and Environmental Sources in Nairobi, Kenya Mycoses. Nov, 2015 | Pubmed ID: 26404188 Mass Spectrometry-based PhyloProteomics (MSPP): A Novel Microbial Typing Method Scientific Reports. Aug, 2015 | Pubmed ID: 26303099 Environmental Isolates of Azole-resistant Aspergillus Fumigatus in Germany Antimicrobial Agents and Chemotherapy. Jul, 2015 | Pubmed ID: 25941229 Salmonella Typhi Meningitis in a 9-year Old Boy with Urinary Schistosomiasis: a Case Report BMC Research Notes. Mar, 2015 | Pubmed ID: 25889776 Campylobacter Jejuni: Components for Adherence to and Invasion of Eukaryotic Cells Berliner Und Munchener Tierarztliche Wochenschrift. Mar-Apr, 2015 | Pubmed ID: 25876267 Two Cases of Chronic Suppurative Otitis Media Caused by Kerstersia Gyiorum in Tanzania: is It an Underappreciated Pathogen in Chronic Otitis Media? International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases. Dec, 2014 | Pubmed ID: 25461666 HIV-serostatus Disclosure in the Context of Free Antiretroviral Therapy and Socio-economic Dependency: Experiences Among Women Living with HIV in Tanzania African Journal of AIDS Research : AJAR. Sep, 2014 | Pubmed ID: 25388976 Diagnosis of Toxoplasmosis Using a Synthetic Glycosylphosphatidylinositol Glycan Angewandte Chemie (International Ed. in English). Dec, 2014 | Pubmed ID: 25323101 Animals Are Key to Human Toxoplasmosis International Journal of Medical Microbiology : IJMM. Oct, 2014 | Pubmed ID: 25240467 Yeast On-target Lysis (YOTL), a Procedure for Making Auxiliary Mass Spectrum Data Sets for Clinical Routine Identification of Yeasts Journal of Clinical Microbiology. Dec, 2014 | Pubmed ID: 25232169 Genotyping of Samples from German Patients with Ocular, Cerebral and Systemic Toxoplasmosis Reveals a Predominance of Toxoplasma Gondii Type II International Journal of Medical Microbiology : IJMM. Oct, 2014 | Pubmed ID: 25037927 Sero-positivity Rate of Rubella and Associated Factors Among Pregnant Women Attending Antenatal Care in Mwanza, Tanzania BMC Pregnancy and Childbirth. Mar, 2014 | Pubmed ID: 24589180 Humoral Immune Responses in Chickens and Turkeys After Infection with Toxoplasma Gondii by Using Recombinant Antigens Parasitology Research. Apr, 2014 | Pubmed ID: 24532010 Modification of Intestinal Microbiota and Its Consequences for Innate Immune Response in the Pathogenesis of Campylobacteriosis Clinical & Developmental Immunology. 2013 | Pubmed ID: 24324507 Effects of Easy-to-perform Procedures to Reduce Bacterial Colonization with Streptococcus Mutans and Staphylococcus Aureus on Toothbrushes European Journal of Microbiology & Immunology. Sep, 2013 | Pubmed ID: 24265940 Discrimination of Multilocus Sequence Typing-based Campylobacter Jejuni Subgroups by MALDI-TOF Mass Spectrometry BMC Microbiology. Nov, 2013 | Pubmed ID: 24195572 Synthesis and Properties of Bridgehead-Functionalized Permethylbicyclo[2.2.2]octasilanes Organometallics. Aug, 2013 | Pubmed ID: 23997386 Prevalence and Antifungal Susceptibility of Cryptococcus Neoformans Isolated from Pigeon Excreta in Chon Buri Province, Eastern Thailand Medical Mycology Journal. 2013 | Pubmed ID: 23995421 Sero-prevalence and Factors Associated with Toxoplasma Gondii Infection Among Pregnant Women Attending Antenatal Care in Mwanza, Tanzania Parasites & Vectors. Aug, 2013 | Pubmed ID: 23915834 Identification of Dihydroorotate Dehydrogenase As a Relevant Drug Target for 1-hydroxyquinolones in Toxoplasma Gondii Molecular and Biochemical Parasitology. Jul, 2013 | Pubmed ID: 23747278 Cyp51A-Based Mechanisms of Aspergillus Fumigatus Azole Drug Resistance Present in Clinical Samples from Germany Antimicrobial Agents and Chemotherapy. Aug, 2013 | Pubmed ID: 23669382 Campylobacter - an Extraordinary Intestinal Bacterium European Journal of Microbiology & Immunology. Mar, 2012 | Pubmed ID: 24611114 Gross Karyotypic and Phenotypic Alterations Among Different Progenies of the Candida Glabrata CBS138/ATCC2001 Reference Strain PloS One. 2012 | Pubmed ID: 23284942 Two Clinical Isolates of Candida Glabrata Exhibiting Reduced Sensitivity to Amphotericin B Both Harbor Mutations in ERG2 Antimicrobial Agents and Chemotherapy. Dec, 2012 | Pubmed ID: 23027188 Epidemiological Association of Campylobacter Jejuni Groups with Pathogenicity-associated Genetic Markers BMC Microbiology. Aug, 2012 | Pubmed ID: 22873291 Rapid Discrimination of Salmonella Enterica Serovar Typhi from Other Serovars by MALDI-TOF Mass Spectrometry PloS One. 2012 | Pubmed ID: 22768195 Facultative Sterol Uptake in an Ergosterol-deficient Clinical Isolate of Candida Glabrata Harboring a Missense Mutation in ERG11 and Exhibiting Cross-resistance to Azoles and Amphotericin B Antimicrobial Agents and Chemotherapy. Aug, 2012 | Pubmed ID: 22615281 Peptide Microarray Analysis of in Silico-predicted Epitopes for Serological Diagnosis of Toxoplasma Gondii Infection in Humans Clinical and Vaccine Immunology : CVI. Jun, 2012 | Pubmed ID: 22496494 Analysis of Clonal Type-specific Antibody Reactions in Toxoplasma Gondii Seropositive Humans from Germany by Peptide-microarray PloS One. 2012 | Pubmed ID: 22470537 Efficacy of Rapid Treatment Initiation Following Primary Toxoplasma Gondii Infection During Pregnancy Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Jun, 2012 | Pubmed ID: 22460980 Photo Quiz. A 32-year-old Man with Ulcerative Mucositis, Skin Lesions, and Nail Dystrophy. Chronic Mucocutaneous Candidiasis by Multidrug-resistant Candida Albicans Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Apr, 2012 | Pubmed ID: 22403094 Interlaboratory Comparison of PCR-based Identification of Candida and Aspergillus DNA in Spiked Blood Samples Mycoses. Sep, 2012 | Pubmed ID: 22248125 Symptoms of the Oral Cavity and Their Association with Local Microbiological and Clinical Findings--a Prospective Survey in Palliative Care Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. Mar, 2012 | Pubmed ID: 21336528 Bacteremia and Antimicrobial Drug Resistance over Time, Ghana Emerging Infectious Diseases. Oct, 2011 | Pubmed ID: 22000360 Communicable Diseases Prioritized for Surveillance and Epidemiological Research: Results of a Standardized Prioritization Procedure in Germany, 2011 PloS One. 2011 | Pubmed ID: 21991334 Two Internal Type II NADH Dehydrogenases of Toxoplasma Gondii Are Both Required for Optimal Tachyzoite Growth Molecular Microbiology. Oct, 2011 | Pubmed ID: 21854467 Brief Communication: Evidence of Bartonella Quintana Infections in Skeletons of a Historical Mass Grave in Kassel, Germany American Journal of Physical Anthropology. Sep, 2011 | Pubmed ID: 21710687 Novel Murine Infection Models Provide Deep Insights into the "ménage à Trois" of Campylobacter Jejuni, Microbiota and Host Innate Immunity PloS One. 2011 | Pubmed ID: 21698299 Pathobiology of Human-pathogenic Fungi International Journal of Medical Microbiology : IJMM. Jun, 2011 | Pubmed ID: 21561805 The Parasitophorous Vacuole of Encephalitozoon Cuniculi: Biogenesis and Characteristics of the Host Cell-pathogen Interface International Journal of Medical Microbiology : IJMM. Jun, 2011 | Pubmed ID: 21550847 Extracellular Toxoplasma Gondii Tachyzoites Do Not Require Carbon Source Uptake for ATP Maintenance, Gliding Motility and Invasion in the First Hour of Their Extracellular Life International Journal for Parasitology. Jul, 2011 | Pubmed ID: 21515276 Sulphite : Cytochrome C Oxidoreductase Deficiency in Campylobacter Jejuni Reduces Motility, Host Cell Adherence and Invasion Microbiology (Reading, England). Jun, 2011 | Pubmed ID: 21372092 Epidemiological Association of Different Campylobacter Jejuni Groups with Metabolism-associated Genetic Markers Applied and Environmental Microbiology. Apr, 2011 | Pubmed ID: 21278270 Identification and Characterization of Four Azole-resistant Erg3 Mutants of Candida Albicans Antimicrobial Agents and Chemotherapy. Nov, 2010 | Pubmed ID: 20733039 Campylobacter Jejuni Proteins Cj0952c and Cj0951c Affect Chemotactic Behaviour Towards Formic Acid and Are Important for Invasion of Host Cells Microbiology (Reading, England). Oct, 2010 | Pubmed ID: 20656782 Analysis of the Cellular Aspergillus Fumigatus Proteome That Reacts with Sera from Rabbits Developing an Acquired Immunity After Experimental Aspergillosis Electrophoresis. Jun, 2010 | Pubmed ID: 20564691 A Clinical Isolate of Candida Albicans with Mutations in ERG11 (encoding Sterol 14alpha-demethylase) and ERG5 (encoding C22 Desaturase) is Cross Resistant to Azoles and Amphotericin B Antimicrobial Agents and Chemotherapy. Sep, 2010 | Pubmed ID: 20547793 The Candida Albicans Cell Wall Protein Rhd3/Pga29 is Abundant in the Yeast Form and Contributes to Virulence Yeast (Chichester, England). Aug, 2010 | Pubmed ID: 20533408 Germination of Phagocytosed E. Cuniculi Spores Does Not Significantly Contribute to Parasitophorous Vacuole Formation in J774 Cells Parasitology Research. Feb, 2010 | Pubmed ID: 20107836 In Vitro and in Vivo Activities of 1-hydroxy-2-alkyl-4(1H)quinolone Derivatives Against Toxoplasma Gondii Antimicrobial Agents and Chemotherapy. Jan, 2010 | Pubmed ID: 19884369 Campylobacter Jejuni: a Brief Overview on Pathogenicity-associated Factors and Disease-mediating Mechanisms International Journal of Medical Microbiology : IJMM. Apr, 2010 | Pubmed ID: 19665925 Comparison Between Pp65 Antigenemia Assay and Quantitative Real-time Polymerase Chain Reaction for Detection of Active Cytomegalovirus Infection in Routine Diagnostics Diagnostic Microbiology and Infectious Disease. Oct, 2009 | Pubmed ID: 19748432 Mammalian Apoptotic Signalling Pathways: Multiple Targets of Protozoan Parasites to Activate or Deactivate Host Cell Death Microbes and Infection. Nov, 2009 | Pubmed ID: 19733682 Immunity to Campylobacter: Its Role in Risk Assessment and Epidemiology Critical Reviews in Microbiology. 2009 | Pubmed ID: 19514906 Spontaneous Stage Differentiation of Mouse-virulent Toxoplasma Gondii RH Parasites in Skeletal Muscle Cells: an Ultrastructural Evaluation Memorias Do Instituto Oswaldo Cruz. Mar, 2009 | Pubmed ID: 19430644 Type II NADH Dehydrogenase Inhibitor 1-hydroxy-2-dodecyl-4(1H)quinolone Leads to Collapse of Mitochondrial Inner-membrane Potential and ATP Depletion in Toxoplasma Gondii Eukaryotic Cell. Jun, 2009 | Pubmed ID: 19286986 Primary Skeletal Muscle Cells Trigger Spontaneous Toxoplasma Gondii Tachyzoite-to-bradyzoite Conversion at Higher Rates Than Fibroblasts International Journal of Medical Microbiology : IJMM. Jun, 2009 | Pubmed ID: 19097936 Modulation of Caspase Activation by Toxoplasma Gondii Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19089389 The Cell Wall of the Human Pathogen Candida Glabrata: Differential Incorporation of Novel Adhesin-like Wall Proteins Eukaryotic Cell. Nov, 2008 | Pubmed ID: 18806209 The Toxoplasma Gondii Type-II NADH Dehydrogenase TgNDH2-I is Inhibited by 1-hydroxy-2-alkyl-4(1H)quinolones Biochimica Et Biophysica Acta. Nov, 2008 | Pubmed ID: 18786503 [From Mycological Basic Research to the Sickbed and Vice Versa--a Laudatio for Prof. Reinhard Rüchel] Mycoses. Sep, 2008 | Pubmed ID: 18782234 Stress-related and Spontaneous Stage Differentiation of Toxoplasma Gondii Molecular BioSystems. Aug, 2008 | Pubmed ID: 18633484 Characterization and Intracellular Localization of Putative Chlamydia Pneumoniae Effector Proteins Medical Microbiology and Immunology. Dec, 2008 | Pubmed ID: 18449565 The Nascent Parasitophorous Vacuole Membrane of Encephalitozoon Cuniculi is Formed by Host Cell Lipids and Contains Pores Which Allow Nutrient Uptake Eukaryotic Cell. Jun, 2008 | Pubmed ID: 18408058 Transient Inhibition of Poly(ADP-ribose) Polymerase Expression and Activity by Toxoplasma Gondii is Dispensable for Parasite-mediated Blockade of Host Cell Apoptosis and Intracellular Parasite Replication Microbes and Infection. Apr, 2008 | Pubmed ID: 18396434 Localisation of Gluconeogenesis and Tricarboxylic Acid (TCA)-cycle Enzymes and First Functional Analysis of the TCA Cycle in Toxoplasma Gondii International Journal for Parasitology. Aug, 2008 | Pubmed ID: 18336823 Identification of Novel Bradyzoite-specific Toxoplasma Gondii Genes with Domains for Protein-protein Interactions by Suppression Subtractive Hybridization Molecular and Biochemical Parasitology. Feb, 2008 | Pubmed ID: 18061287 Epidemiology and Antifungal Susceptibilities of Candida Spp. to Six Antifungal Agents: Results from a Surveillance Study on Fungaemia in Germany from July 2004 to August 2005 The Journal of Antimicrobial Chemotherapy. Aug, 2007 | Pubmed ID: 17562683 Role of the Plasmid-encoded Tet(O) Gene in Tetracycline-resistant Clinical Isolates of Campylobacter Jejuni and Campylobacter Coli Journal of Medical Microbiology. Jun, 2007 | Pubmed ID: 17510271 Carbohydrate Metabolism in the Toxoplasma Gondii Apicoplast: Localization of Three Glycolytic Isoenzymes, the Single Pyruvate Dehydrogenase Complex, and a Plastid Phosphate Translocator Eukaryotic Cell. Jun, 2007 | Pubmed ID: 17449654 Toxoplasma Gondii Inhibits Fas/CD95-triggered Cell Death by Inducing Aberrant Processing and Degradation of Caspase 8 Cellular Microbiology. Jun, 2007 | Pubmed ID: 17298390 Growth Inhibition of Toxoplasma Gondii and Plasmodium Falciparum by Nanomolar Concentrations of 1-hydroxy-2-dodecyl-4(1H)quinolone, a High-affinity Inhibitor of Alternative (type II) NADH Dehydrogenases Antimicrobial Agents and Chemotherapy. Apr, 2007 | Pubmed ID: 17242151 Subversion of Innate and Adaptive Immune Responses by Toxoplasma Gondii Parasitology Research. Jan, 2007 | Pubmed ID: 17024357 Identification of Novel Developmentally Regulated Genes in Encephalitozoon Cuniculi: an Endochitinase, a Chitin-synthase, and Two Subtilisin-like Proteases Are Induced During Meront-to-sporont Differentiation The Journal of Eukaryotic Microbiology. 2006 | Pubmed ID: 17169074 Candida and Candidosis Today: Where Are We, and Where to Go? The Interdisciplinary Forum on Candidosis (IFOCAN) 2005, Göttingen (Germany), 23-25 September 2005 FEMS Yeast Research. Dec, 2006 | Pubmed ID: 17156027 Improved Serological Diagnosis Stresses the Major Role of Campylobacter Jejuni in Triggering Guillain-Barré Syndrome Clinical and Vaccine Immunology : CVI. Jul, 2006 | Pubmed ID: 16829615 Diverse Mechanisms Employed by Toxoplasma Gondii to Inhibit IFN-gamma-induced Major Histocompatibility Complex Class II Gene Expression Microbes and Infection. Jul, 2006 | Pubmed ID: 16824778 Direct Inhibition of Cytochrome C-induced Caspase Activation in Vitro by Toxoplasma Gondii Reveals Novel Mechanisms of Interference with Host Cell Apoptosis FEMS Microbiology Letters. May, 2006 | Pubmed ID: 16640590 Disruption of the Bradyzoite-specific P-type (H+)-ATPase PMA1 in Toxoplasma Gondii Leads to Decreased Bradyzoite Differentiation After Stress Stimuli but Does Not Interfere with Mature Tissue Cyst Formation Molecular and Biochemical Parasitology. Mar, 2006 | Pubmed ID: 16375982 Improved Serodiagnosis of Campylobacter Jejuni Infections Using Recombinant Antigens Journal of Medical Microbiology. Aug, 2005 | Pubmed ID: 16014430 Bacteremia Among Kenyan Children The New England Journal of Medicine. Mar, 2005 | Pubmed ID: 15803526 The Parasitophorous Vacuole Membrane of Encephalitozoon Cuniculi Lacks Host Cell Membrane Proteins Immediately After Invasion Eukaryotic Cell. Jan, 2005 | Pubmed ID: 15643077 Identification and Characterization of a Major Subgroup of Conjugative Campylobacter Jejuni Plasmids The Journal of Infection. Jan, 2005 | Pubmed ID: 15603835 Systematic Identification in Silico of Covalently Bound Cell Wall Proteins and Analysis of Protein-polysaccharide Linkages of the Human Pathogen Candida Glabrata Microbiology (Reading, England). Oct, 2004 | Pubmed ID: 15470094 Transferrin Receptor Induction in Toxoplasma Gondii-infected HFF is Associated with Increased Iron-responsive Protein 1 Activity and is Mediated by Secreted Factors Parasitology Research. Oct, 2004 | Pubmed ID: 15349772 Impact of Stage Differentiation on Diagnosis of Toxoplasmosis Annali Dell'Istituto Superiore Di Sanita. 2004 | Pubmed ID: 15269454 Reduced Expression of the Inducible Nitric Oxide Synthase After Infection with Toxoplasma Gondii Facilitates Parasite Replication in Activated Murine Macrophages International Journal for Parasitology. Jul, 2003 | Pubmed ID: 12865083 Treatment of Microsporidiosis Including Albendazole Parasitology Research. Jun, 2003 | Pubmed ID: 12811545 Toxoplasma Gondii Inhibits MHC Class II Expression in Neural Antigen-presenting Cells by Down-regulating the Class II Transactivator CIITA Journal of Neuroimmunology. Jan, 2003 | Pubmed ID: 12507768 Monocyte Chemotactic Protein-1 Secretion and Expression After Toxoplasma Gondii Infection in Vitro Depend on the Stage of the Parasite FEMS Microbiology Letters. Aug, 2002 | Pubmed ID: 12204371 Effect of Micafungin (FK463) on Candida Albicans Adherence to Epithelial Cells Chemotherapy. Jul, 2002 | Pubmed ID: 12138332 Human Deep Tissue Infection with an Entomopathogenic Beauveria Species Journal of Clinical Microbiology. Jul, 2002 | Pubmed ID: 12089314 Adherence of Different Candida Dubliniensis Isolates in the Presence of Fluconazole AIDS (London, England). Jun, 2002 | Pubmed ID: 12045488 [Characteristics of Toxoplasma-gondii-tachyzoites from Different Culture Systems] ALTEX. 1998 | Pubmed ID: 11178537 Subtyping of Campylobacter jejuni ssp. doylei Isolates Using Mass Spectrometry-based PhyloProteomics (MSPP) Andreas E. Zautner1, Raimond Lugert1, Wycliffe O. Masanta1, Michael Weig1, Uwe Groß1, Oliver Bader1 1Institut für Medizinische Mikrobiologie, Universitätsmedizin Göttingen JoVE 54165 Génétique
Subtyping of Campylobacter jejuni ssp. doylei Isolates Using Mass Spectrometry-based PhyloProteomics (MSPP) Andreas E. Zautner1, Raimond Lugert1, Wycliffe O. Masanta1, Michael Weig1, Uwe Groß1, Oliver Bader1 1Institut für Medizinische Mikrobiologie, Universitätsmedizin Göttingen JoVE 54165 Génétique