V. Wee Yong

Publications

• Fibulin-2 is an Extracellular Matrix Inhibitor of Oligodendrocytes Relevant to Multiple Sclerosis
  The Journal of Clinical Investigation. May, 2024  |   Pubmed ID: 38743490
• From Progression to Progress: The Future of Multiple Sclerosis
  Journal of Central Nervous System Disease. 2024  |   Pubmed ID: 38711957
• The Cerebroprotection and Prospects of FNDC5/irisin in Stroke
  Neuropharmacology. Aug, 2024  |   Pubmed ID: 38705569
• LXR Agonism for CNS Diseases: Promises and Challenges
  Journal of Neuroinflammation. Apr, 2024  |   Pubmed ID: 38627787
• Genetically Predicted Hypotaurine Levels Mediate the Relationship Between Immune Cells and Intracerebral Hemorrhage
  International Immunopharmacology. May, 2024  |   Pubmed ID: 38608476
• Biology of Neurofibrosis with Focus on Multiple Sclerosis
  Frontiers in Immunology. 2024  |   Pubmed ID: 38596673
• Adjudin Protects Blood-brain Barrier Integrity and Attenuates Neuroinflammation Following Intracerebral Hemorrhage in Mice
  International Immunopharmacology. May, 2024  |   Pubmed ID: 38565042
• Feasibility Study to Assess Lesion Repair in Relapsing-remitting Multiple Sclerosis: A Randomized Controlled Pilot Clinical Trial of Domperidone Add-on Treatment
  Multiple Sclerosis and Related Disorders. May, 2024  |   Pubmed ID: 38461731
• Uncovering Novel Extracellular Matrix Transcriptome Alterations in Lesions of Multiple Sclerosis
  International Journal of Molecular Sciences. Jan, 2024  |   Pubmed ID: 38279239
• Towards Improving the Prognosis of Stroke Through Targeting the Circadian Clock System
  International Journal of Biological Sciences. 2024  |   Pubmed ID: 38169640
• Ion Channel Dysregulation Following Intracerebral Hemorrhage
  Neuroscience Bulletin. Mar, 2024  |   Pubmed ID: 37755675
• Crosstalk Between Matrix Metalloproteinases and Their Inducer EMMPRIN/CD147: a Promising Therapeutic Target for Intracerebral Hemorrhage
  Translational Stroke Research. Dec, 2023  |   Pubmed ID: 38100014
• Prominent Elevation of Extracellular Matrix Molecules in Intracerebral Hemorrhage
  Frontiers in Molecular Neuroscience. 2023  |   Pubmed ID: 38025264
• Early Life Stress Aggravates Disease Pathogenesis in Mice with Experimental Autoimmune Encephalomyelitis: Support for a Two-hit Hypothesis of Multiple Sclerosis Etiology
  Journal of Neuroimmunology. Dec, 2023  |   Pubmed ID: 37951203
• Anti-oxidant Effects of Cannabidiol Relevant to Intracerebral Hemorrhage
  Frontiers in Pharmacology. 2023  |   Pubmed ID: 37841923
• Tolerability of Subcutaneous Ofatumumab with Long-term Exposure in Relapsing Multiple Sclerosis
  Multiple Sclerosis Journal - Experimental, Translational and Clinical. 2023  |   Pubmed ID: 37829441
• The Extracellular Matrix As Modifier of Neuroinflammation and Recovery in Ischemic Stroke and Intracerebral Hemorrhage
  Neurobiology of Disease. Oct, 2023  |   Pubmed ID: 37683956
• Omarigliptin Inhibits Brain Cell Ferroptosis After Intracerebral Hemorrhage
  Scientific Reports. Sep, 2023  |   Pubmed ID: 37658227
• Distinct Characteristics and Severity of Brain Magnetic Resonance Imaging Lesions in Women and Men with Multiple Sclerosis Assessed Using Verified Texture Analysis Measures
  Frontiers in Neurology. 2023  |   Pubmed ID: 37638198
• Iron in Multiple Sclerosis - Neuropathology, Immunology, and Real-world Considerations
  Multiple Sclerosis and Related Disorders. Oct, 2023  |   Pubmed ID: 37579645
• Omarigliptin Protects the Integrity of the Blood-Brain Barrier After Intracerebral Hemorrhage in Mice
  Journal of Inflammation Research. 2023  |   Pubmed ID: 37342770
• Elevated Galectin-3 Is Associated with Aging, Multiple Sclerosis, and Oxidized Phosphatidylcholine-Induced Neurodegeneration
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2023  |   Pubmed ID: 37208177
• Enhanced Liver X Receptor Signalling Reduces Brain Injury and Promotes Tissue Regeneration Following Experimental Intracerebral Haemorrhage: Roles of Microglia/macrophages
  Stroke and Vascular Neurology. Dec, 2023  |   Pubmed ID: 37137522
• Single Cell Analysis of High-Parameter Histology Images Using Histoflow Cytometry
  Journal of Immunology (Baltimore, Md. : 1950). Jun, 2023  |   Pubmed ID: 37133337
• The Promise of Niacin in Neurology
  Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Jul, 2023  |   Pubmed ID: 37084148
• Single-Cell Spatial Analysis Identifies Regulators of Brain Tumor-Initiating Cells
  Cancer Research. May, 2023  |   Pubmed ID: 37067922
• Multiple Sclerosis Progression: Time for a New Mechanism-driven Framework
  The Lancet. Neurology. Jan, 2023  |   Pubmed ID: 36410373
• Serum Neurofilament-light and Glial Fibrillary Acidic Protein Levels in Hydroxychloroquine-treated Primary Progressive Multiple Sclerosis
  European Journal of Neurology. Jan, 2023  |   Pubmed ID: 36214614
• Detecting Monocyte Trafficking in an Animal Model of Glioblastoma Using R* and Quantitative Susceptibility Mapping
  Cancer Immunology, Immunotherapy : CII. Mar, 2023  |   Pubmed ID: 36194288
• Obesity in Acute Ischaemic Stroke Patients Treated with Intravenous Thrombolysis Therapy
  Neurological Research. Sep, 2023  |   Pubmed ID: 34112057
• Single-cell and Spatial RNA Sequencing Identify Perturbators of Microglial Functions with Aging
  Nature Aging. Jun, 2022  |   Pubmed ID: 37118444
• The Important Role of Zinc in Neurological Diseases
  Biomolecules. Dec, 2022  |   Pubmed ID: 36671413
• Therapeutic Strategies for Intracerebral Hemorrhage
  Frontiers in Neurology. 2022  |   Pubmed ID: 36408517
• Bladder Dysfunction in Experimental Autoimmune Encephalomyelitis Reflects Clinical Severity: A Pilot Study
  Journal of Neuroimmunology. Nov, 2022  |   Pubmed ID: 36209613
• Aging Microglia: Old Friends Greet New Enemies
  Aging. Sep, 2022  |   Pubmed ID: 36173626
• Extracellular Matrix Metalloproteinase Inducer in Brain Ischemia and Intracerebral Hemorrhage
  Frontiers in Immunology. 2022  |   Pubmed ID: 36119117
• Microglia-T Cell Conversations in Brain Cancer Progression
  Trends in Molecular Medicine. Nov, 2022  |   Pubmed ID: 36075812
• Neuroprotective Effects of Chlorogenic Acid in a Mouse Model of Intracerebral Hemorrhage Associated with Reduced Extracellular Matrix Metalloproteinase Inducer
  Biomolecules. Jul, 2022  |   Pubmed ID: 35892330
• Expression of Antioxidant Enzymes in Lesions of Multiple Sclerosis and Its Models
  Scientific Reports. Jul, 2022  |   Pubmed ID: 35882921
• Microglia in Multiple Sclerosis: Protectors Turn Destroyers
  Neuron. Nov, 2022  |   Pubmed ID: 35882229
• Minocycline Treatment in Clinically Isolated Syndrome and Serum NfL, GFAP, and Metalloproteinase Levels
  Multiple Sclerosis (Houndmills, Basingstoke, England). Nov, 2022  |   Pubmed ID: 35848622
• Neuroprotection by Ozanimod Following Intracerebral Hemorrhage in Mice
  Frontiers in Molecular Neuroscience. 2022  |   Pubmed ID: 35782389
• Iron Neurotoxicity and Protection by Deferoxamine in Intracerebral Hemorrhage
  Frontiers in Molecular Neuroscience. 2022  |   Pubmed ID: 35782383
• Necrosulfonamide Alleviates Acute Brain Injury of Intracerebral Hemorrhage Inhibiting Inflammation and Necroptosis
  Frontiers in Molecular Neuroscience. 2022  |   Pubmed ID: 35721316
• Thermoregulatory Dynamics Reveal Sex-specific Inflammatory Responses to Experimental Autoimmune Encephalomyelitis in Mice: Implications for Multiple Sclerosis-induced Fatigue in Females
  Brain, Behavior, & Immunity - Health. Aug, 2022  |   Pubmed ID: 35677535
• Microglia in Multiple Sclerosis - Pathogenesis and Imaging
  Current Opinion in Neurology. Jun, 2022  |   Pubmed ID: 35674072
• EMMPRIN Promotes the Expression of MMP-9 and Exacerbates Neurological Dysfunction in a Mouse Model of Intracerebral Hemorrhage
  Neurochemical Research. Aug, 2022  |   Pubmed ID: 35608790
• Versican Promotes T Helper 17 Cytotoxic Inflammation and Impedes Oligodendrocyte Precursor Cell Remyelination
  Nature Communications. May, 2022  |   Pubmed ID: 35508608
• Revisiting Minocycline in Intracerebral Hemorrhage: Mechanisms and Clinical Translation
  Frontiers in Immunology. 2022  |   Pubmed ID: 35401553
• Oxidized Phospholipids As Novel Mediators of Neurodegeneration
  Trends in Neurosciences. Jun, 2022  |   Pubmed ID: 35393134
• Matrix Metalloproteinase-9 As an Important Contributor to the Pathophysiology of Depression
  Frontiers in Neurology. 2022  |   Pubmed ID: 35370878
• Oxidative Stress Following Intracerebral Hemorrhage: From Molecular Mechanisms to Therapeutic Targets
  Frontiers in Immunology. 2022  |   Pubmed ID: 35355999
• Exercise Training in Multiple Sclerosis
  The Lancet. Neurology. Apr, 2022  |   Pubmed ID: 35305335
• Vildagliptin Improves Neurological Function by Inhibiting Apoptosis and Ferroptosis Following Intracerebral Hemorrhage in Mice
  Neuroscience Letters. Apr, 2022  |   Pubmed ID: 35304193
• Modes of Brain Cell Death Following Intracerebral Hemorrhage
  Frontiers in Cellular Neuroscience. 2022  |   Pubmed ID: 35185473
• A Distinct Extract Prevents Iron Neurotoxicity, a Driver of Multiple Sclerosis Pathology
  Cells. Jan, 2022  |   Pubmed ID: 35159249
• Remyelination Trial Failures: Repercussions of Ignoring Neurorehabilitation and Exercise in Repair
  Multiple Sclerosis and Related Disorders. Feb, 2022  |   Pubmed ID: 35066276
• B Cells in Central Nervous System Disease: Diversity, Locations and Pathophysiology
  Nature Reviews. Immunology. Aug, 2022  |   Pubmed ID: 34903877
• Quantitative Analysis of Spinal Cord Neuropathology in Experimental Autoimmune Encephalomyelitis
  Journal of Neuroimmunology. Jan, 2022  |   Pubmed ID: 34823122
• Mechanism-based Criteria to Improve Therapeutic Outcomes in Progressive Multiple Sclerosis
  Nature Reviews. Neurology. Jan, 2022  |   Pubmed ID: 34732831
• Exercise and the Brain in Multiple Sclerosis
  Multiple Sclerosis (Houndmills, Basingstoke, England). Jul, 2022  |   Pubmed ID: 33124511
• Gap Junctions and Hemichannels Composed of Connexins and Pannexins Mediate the Secondary Brain Injury Following Intracerebral Hemorrhage
  Biology. Dec, 2021  |   Pubmed ID: 35053024
• PD-1 Independent of PD-L1 Ligation Promotes Glioblastoma Growth Through the NFκB Pathway
  Science Advances. Nov, 2021  |   Pubmed ID: 34739319
• The Canadian Prospective Cohort Study to Understand Progression in Multiple Sclerosis (CanProCo): Rationale, Aims, and Study Design
  BMC Neurology. Oct, 2021  |   Pubmed ID: 34706670
• MedXercise: a Promising Strategy to Promote Remyelination
  Current Opinion in Pharmacology. Dec, 2021  |   Pubmed ID: 34688996
• Central Nervous System Tissue Regeneration After Intracerebral Hemorrhage: The Next Frontier
  Cells. Sep, 2021  |   Pubmed ID: 34685493
• Neuroprotection of Minocycline by Inhibition of Extracellular Matrix Metalloproteinase Inducer Expression Following Intracerebral Hemorrhage in Mice
  Neuroscience Letters. Nov, 2021  |   Pubmed ID: 34666120
• Studying the Microglia Response to Oxidized Phosphatidylcholine in Primary Mouse Neuron Culture and Mouse Spinal Cord
  STAR Protocols. Dec, 2021  |   Pubmed ID: 34622221
• Hydroxychloroquine for Primary Progressive Multiple Sclerosis
  Annals of Neurology. Dec, 2021  |   Pubmed ID: 34590328
• Does Chronic Jet Lag Increase Risk of Cancer?
  Aging. Sep, 2021  |   Pubmed ID: 34586082
• Susceptibility Weighted Imaging Detects Prominent Veins That Precede or Coincide with Maximal Motor Disability in a Model of Multiple Sclerosis: A Pilot Study
  Multiple Sclerosis and Related Disorders. Sep, 2021  |   Pubmed ID: 34243102
• An X-ray for Myelin
  Trends in Neurosciences. Aug, 2021  |   Pubmed ID: 34148671
• The Combination of Deferoxamine and Minocycline Strengthens Neuroprotective Effect on Acute Intracerebral Hemorrhage in Rats
  Neurological Research. Oct, 2021  |   Pubmed ID: 34107863
• Repurposing Domperidone in Secondary Progressive Multiple Sclerosis: A Simon 2-Stage Phase 2 Futility Trial
  Neurology. May, 2021  |   Pubmed ID: 34038379
• The Extracellular Matrix As Modifier of Neuroinflammation and Remyelination in Multiple Sclerosis
  Brain : a Journal of Neurology. Aug, 2021  |   Pubmed ID: 33889940
• Exercise Rapidly Alters Proteomes in Mice Following Spinal Cord Demyelination
  Scientific Reports. Mar, 2021  |   Pubmed ID: 33790323
• Harnessing the Benefits of Neuroinflammation: Generation of Macrophages/Microglia with Prominent Remyelinating Properties
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Apr, 2021  |   Pubmed ID: 33712513
• Fibrinogen in the Glioblastoma Microenvironment Contributes to the Invasiveness of Brain Tumor-initiating Cells
  Brain Pathology (Zurich, Switzerland). Sep, 2021  |   Pubmed ID: 33694259
• Circadian Disruption in Mice Through Chronic Jet Lag-like Conditions Modulates Molecular Profiles of Cancer in Nucleus Accumbens and Prefrontal Cortex
  Carcinogenesis. Jun, 2021  |   Pubmed ID: 33608694
• Oxidized Phosphatidylcholines Found in Multiple Sclerosis Lesions Mediate Neurodegeneration and Are Neutralized by Microglia
  Nature Neuroscience. Apr, 2021  |   Pubmed ID: 33603230
• Multimodal Peripheral Fluid Biomarker Analysis in Clinically Isolated Syndrome and Early Multiple Sclerosis
  Multiple Sclerosis and Related Disorders. May, 2021  |   Pubmed ID: 33581614
• Combination of Hydroxychloroquine and Indapamide Attenuates Neurodegeneration in Models Relevant to Multiple Sclerosis
  Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Jan, 2021  |   Pubmed ID: 33410109
• Neuregulin-1 Beta 1 is Implicated in Pathogenesis of Multiple Sclerosis
  Brain : a Journal of Neurology. Feb, 2021  |   Pubmed ID: 33313801
• Metabolic Needs of Brain-infiltrating Leukocytes and Microglia in Multiple Sclerosis
  Journal of Neurochemistry. Jul, 2021  |   Pubmed ID: 33025576
• Intracerebral Haemorrhage: from Clinical Settings to Animal Models
  Stroke and Vascular Neurology. Dec, 2020  |   Pubmed ID: 33376200
• Neuroinflammation in Intracerebral Haemorrhage: Immunotherapies with Potential for Translation
  The Lancet. Neurology. Dec, 2020  |   Pubmed ID: 33212054
• Aging-Exacerbated Acute Axon and Myelin Injury Is Associated with Microglia-Derived Reactive Oxygen Species and Is Alleviated by the Generic Medication Indapamide
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2020  |   Pubmed ID: 33060175
• Glioma-derived IL-33 Orchestrates an Inflammatory Brain Tumor Microenvironment That Accelerates Glioma Progression
  Nature Communications. Oct, 2020  |   Pubmed ID: 33020472
• Beyond Barrier Functions: Roles of Pericytes in Homeostasis and Regulation of Neuroinflammation
  Journal of Neuroscience Research. Dec, 2020  |   Pubmed ID: 32815569
• Author Correction: Single-cell RNA-seq Reveals That Glioblastoma Recapitulates a Normal Neurodevelopmental Hierarchy
  Nature Communications. Aug, 2020  |   Pubmed ID: 32769982
• The Glycosyltransferase EXTL2 Promotes Proteoglycan Deposition and Injurious Neuroinflammation Following Demyelination
  Journal of Neuroinflammation. Jul, 2020  |   Pubmed ID: 32703234
• Control of Brain Tumor Growth by Reactivating Myeloid Cells with Niacin
  Science Translational Medicine. Apr, 2020  |   Pubmed ID: 32238578
• Correction To: Niacin-mediated Rejuvenation of Macrophage/microglia Enhances Remyelination of the Aging Central Nervous System
  Acta Neuropathologica. May, 2020  |   Pubmed ID: 32211925
• Demeclocycline Reduces the Growth of Human Brain Tumor-Initiating Cells: Direct Activity and Through Monocytes
  Frontiers in Immunology. 2020  |   Pubmed ID: 32153581
• Niacin-mediated Rejuvenation of Macrophage/microglia Enhances Remyelination of the Aging Central Nervous System
  Acta Neuropathologica. May, 2020  |   Pubmed ID: 32030468
• Microglia Response Following Acute Demyelination is Heterogeneous and Limits Infiltrating Macrophage Dispersion
  Science Advances. Jan, 2020  |   Pubmed ID: 31998844
• Microglia and Macrophage Phenotypes in Intracerebral Haemorrhage Injury: Therapeutic Opportunities
  Brain : a Journal of Neurology. May, 2020  |   Pubmed ID: 31919518
• 2-arachidonoylglycerol Reduces Chondroitin Sulphate Proteoglycan Production by Astrocytes and Enhances Oligodendrocyte Differentiation Under Inhibitory Conditions
  Glia. Jun, 2020  |   Pubmed ID: 31894889
• Exercise in Multiple Sclerosis and Its Models: Focus on the Central Nervous System Outcomes
  Journal of Neuroscience Research. Mar, 2020  |   Pubmed ID: 31486115
• Biomarkers of Intestinal Barrier Function in Multiple Sclerosis Are Associated with Disease Activity
  Multiple Sclerosis (Houndmills, Basingstoke, England). Oct, 2020  |   Pubmed ID: 31317818
• When Encephalitogenic T Cells Collaborate with Microglia in Multiple Sclerosis
  Nature Reviews. Neurology. Dec, 2019  |   Pubmed ID: 31527807
• Targeting the Chondroitin Sulfate Proteoglycans: Evaluating Fluorinated Glucosamines and Xylosides in Screens Pertinent to Multiple Sclerosis
  ACS Central Science. Jul, 2019  |   Pubmed ID: 31404231
• Progressive Multiple Sclerosis: from Pathophysiology to Therapeutic Strategies
  Nature Reviews. Drug Discovery. 12, 2019  |   Pubmed ID: 31399729
• Central Nervous System Targeted Autoimmunity Causes Regional Atrophy: a 9.4T MRI Study of the EAE Mouse Model of Multiple Sclerosis
  Scientific Reports. Jun, 2019  |   Pubmed ID: 31186441
• Domperidone-induced Elevation of Serum Prolactin Levels and Immune Response in Multiple Sclerosis
  Journal of Neuroimmunology. Sep, 2019  |   Pubmed ID: 31174092
• Differential Microglia and Macrophage Profiles in Human IDH-mutant and -wild Type Glioblastoma
  Oncotarget. May, 2019  |   Pubmed ID: 31139325
• Enhanced Glycolytic Metabolism Supports Transmigration of Brain-infiltrating Macrophages in Multiple Sclerosis
  The Journal of Clinical Investigation. May, 2019  |   Pubmed ID: 31112527
• The Benefits of Neuroinflammation for the Repair of the Injured Central Nervous System
  Cellular & Molecular Immunology. Jun, 2019  |   Pubmed ID: 30874626
• Efficacy of Minocycline in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of Rodent and Clinical Studies
  Frontiers in Neurology. 2018  |   Pubmed ID: 30619060
• Microglia Induces Gas1 Expression in Human Brain Tumor-initiating Cells to Reduce Tumorigenecity
  Scientific Reports. Oct, 2018  |   Pubmed ID: 30327548
• Focus on the Gut-brain Axis: Multiple Sclerosis, the Intestinal Barrier and the Microbiome
  World Journal of Gastroenterology. Oct, 2018  |   Pubmed ID: 30310254
• Brain Tumor-initiating Cells Export Tenascin-C Associated with Exosomes to Suppress T Cell Activity
  Oncoimmunology. 2018  |   Pubmed ID: 30288344
• Multimodal Enhancement of Remyelination by Exercise with a Pivotal Role for Oligodendroglial PGC1α
  Cell Reports. Sep, 2018  |   Pubmed ID: 30232000
• Cerebrospinal Fluid Biomarkers in Human Spinal Cord Injury from a Phase II Minocycline Trial
  Journal of Neurotrauma. Aug, 2018  |   Pubmed ID: 30074872
• Expanding the Potential Therapeutic Options for Remote Ischemic Preconditioning: Use in Multiple Sclerosis
  Frontiers in Neurology. 2018  |   Pubmed ID: 29971043
• MR Imaging of Tumor-Associated Macrophages: The Next Frontier in Cancer Imaging
  Magnetic Resonance Insights. 2018  |   Pubmed ID: 29780249
• Pro-inflammatory Roles of Chondroitin Sulfate Proteoglycans in Disorders of the Central Nervous System
  Matrix Biology : Journal of the International Society for Matrix Biology. Apr, 2018  |   Pubmed ID: 29702175
• The Extracellular Matrix: Focus on Oligodendrocyte Biology and Targeting CSPGs for Remyelination Therapies
  Glia. Sep, 2018  |   Pubmed ID: 29603376
• Chondroitin Sulfate Proteoglycans As Novel Drivers of Leucocyte Infiltration in Multiple Sclerosis
  Brain : a Journal of Neurology. Apr, 2018  |   Pubmed ID: 29506186
• Deficient Surveillance and Phagocytic Activity of Myeloid Cells Within Demyelinated Lesions in Aging Mice Visualized by Live Multiphoton Imaging
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2018  |   Pubmed ID: 29363580
• Mechanisms of Lysophosphatidylcholine-induced Demyelination: A Primary Lipid Disrupting Myelinopathy
  Glia. Feb, 2018  |   Pubmed ID: 29068088
• Unexpected Additive Effects of Minocycline and Hydroxychloroquine in Models of Multiple Sclerosis: Prospective Combination Treatment for Progressive Disease?
  Multiple Sclerosis (Houndmills, Basingstoke, England). 10, 2018  |   Pubmed ID: 28857721
• Systematic Screening of Generic Drugs for Progressive Multiple Sclerosis Identifies Clomipramine As a Promising Therapeutic
  Nature Communications. Dec, 2017  |   Pubmed ID: 29259169
• Remyelination Therapies: a New Direction and Challenge in Multiple Sclerosis
  Nature Reviews. Drug Discovery. Sep, 2017  |   Pubmed ID: 28685761
• Stop Inflammation and You Stop Neurodegeneration in MS - YES
  Multiple Sclerosis (Houndmills, Basingstoke, England). Sep, 2017  |   Pubmed ID: 28463075
• Gestational Bisphenol-A Exposure Lowers the Threshold for Autoimmunity in a Model of Multiple Sclerosis
  Proceedings of the National Academy of Sciences of the United States of America. 05, 2017  |   Pubmed ID: 28439012
• Activation of NOTCH Signaling by Tenascin-C Promotes Growth of Human Brain Tumor-Initiating Cells
  Cancer Research. 06, 2017  |   Pubmed ID: 28416488
• Glioblastoma-associated Microglia and Macrophages: Targets for Therapies to Improve Prognosis
  Brain : a Journal of Neurology. Jun, 2017  |   Pubmed ID: 28334886
• Unique Spectral Signatures of the Nucleic Acid Dye Acridine Orange Can Distinguish Cell Death by Apoptosis and Necroptosis
  The Journal of Cell Biology. Apr, 2017  |   Pubmed ID: 28264914
• T Cell Exhaustion in Glioblastoma: Intricacies of Immune Checkpoints
  Trends in Immunology. 02, 2017  |   Pubmed ID: 27964820
• MRI Monitoring of Monocytes to Detect Immune Stimulating Treatment Response in Brain Tumor
  Neuro-oncology. Mar, 2017  |   Pubmed ID: 27571884
• Impact of Minocycline on Extracellular Matrix Metalloproteinase Inducer, a Factor Implicated in Multiple Sclerosis Immunopathogenesis
  Journal of Immunology (Baltimore, Md. : 1950). 11, 2016  |   Pubmed ID: 27733550
• Evaluating Soluble EMMPRIN As a Marker of Disease Activity in Multiple Sclerosis: Studies of Serum and Cerebrospinal Fluid
  PloS One. 2016  |   Pubmed ID: 27727297
• Myeloid Cells - Targets of Medication in Multiple Sclerosis
  Nature Reviews. Neurology. Sep, 2016  |   Pubmed ID: 27514287
• Regenerative Capacity of Macrophages for Remyelination
  Frontiers in Cell and Developmental Biology. 2016  |   Pubmed ID: 27243011
• An Inhibitor of Chondroitin Sulfate Proteoglycan Synthesis Promotes Central Nervous System Remyelination
  Nature Communications. Apr, 2016  |   Pubmed ID: 27115988
• Demyelination Induces Transport of Ribosome-containing Vesicles from Glia to Axons: Evidence from Animal Models and MS Patient Brains
  Molecular Biology Reports. Jun, 2016  |   Pubmed ID: 27115494
• Activity-Dependent and Experience-Driven Myelination Provide New Directions for the Management of Multiple Sclerosis
  Trends in Neurosciences. 06, 2016  |   Pubmed ID: 27113322
• Immunosenescence of Microglia and Macrophages: Impact on the Ageing Central Nervous System
  Brain : a Journal of Neurology. Mar, 2016  |   Pubmed ID: 26912633
• Expanding Antigen-specific Regulatory Networks to Treat Autoimmunity
  Nature. Feb, 2016  |   Pubmed ID: 26886799
• Monocytes Increase Human Cardiac Myofibroblast-mediated Extracellular Matrix Remodeling Through TGF-β1
  American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2016  |   Pubmed ID: 26801303
• Multi-scale MRI Spectrum Detects Differences in Myelin Integrity Between MS Lesion Types
  Multiple Sclerosis (Houndmills, Basingstoke, England). Oct, 2016  |   Pubmed ID: 26754802
• 1,25-Dihydroxyvitamin D3 Protects Against Immune-Mediated Killing of Neurons in Culture and in Experimental Autoimmune Encephalomyelitis
  PloS One. 2015  |   Pubmed ID: 26679341
• Fluorescent Phosphorus Dendrimer As a Spectral Nanosensor for Macrophage Polarization and Fate Tracking in Spinal Cord Injury
  Macromolecular Bioscience. Nov, 2015  |   Pubmed ID: 26175127
• Detecting Deoxyhemoglobin in Spinal Cord Vasculature of the Experimental Autoimmune Encephalomyelitis Mouse Model of Multiple Sclerosis Using Susceptibility MRI and Hyperoxygenation
  PloS One. 2015  |   Pubmed ID: 25992667
• The Role of EMMPRIN in T Cell Biology and Immunological Diseases
  Journal of Leukocyte Biology. Jul, 2015  |   Pubmed ID: 25977287
• Prolactin in Combination with Interferon-β Reduces Disease Severity in an Animal Model of Multiple Sclerosis
  Journal of Neuroinflammation. Mar, 2015  |   Pubmed ID: 25889599
• Inefficient Clearance of Myelin Debris by Microglia Impairs Remyelinating Processes
  The Journal of Experimental Medicine. Mar, 2015  |   Pubmed ID: 25779633
• The Promise of Futility Trials in Neurological Diseases
  Nature Reviews. Neurology. Mar, 2015  |   Pubmed ID: 25776824
• ADAM-9 is a Novel Mediator of Tenascin-C-stimulated Invasiveness of Brain Tumor-initiating Cells
  Neuro-oncology. Feb, 2015  |   Pubmed ID: 25646025
• EMMPRIN, an Upstream Regulator of MMPs, in CNS Biology
  Matrix Biology : Journal of the International Society for Matrix Biology. Jan, 2015  |   Pubmed ID: 25644103
• Stimulation of Monocytes, Macrophages, and Microglia by Amphotericin B and Macrophage Colony-stimulating Factor Promotes Remyelination
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2015  |   Pubmed ID: 25609628
• Serum Neurofilament Light Chain is a Biomarker of Human Spinal Cord Injury Severity and Outcome
  Journal of Neurology, Neurosurgery, and Psychiatry. Mar, 2015  |   Pubmed ID: 24935984
• Laquinimod Reduces Neuroaxonal Injury Through Inhibiting Microglial Activation
  Annals of Clinical and Translational Neurology. Jun, 2014  |   Pubmed ID: 25356411
• The Battle for the Brain: Brain Tumor-initiating Cells Vs. Microglia/macrophages
  Oncoimmunology. 2014  |   Pubmed ID: 25340004
• Cellular Factors Promoting Resistance to Effective Treatment of Glioma with Oncolytic Myxoma Virus
  Cancer Research. Dec, 2014  |   Pubmed ID: 25336188
• Changes in Tissue Directionality Reflect Differences in Myelin Content After Demyelination in Mice Spinal Cords
  Journal of Structural Biology. Nov, 2014  |   Pubmed ID: 25281497
• Interactions Between Microglia and T Cells in Multiple Sclerosis Pathobiology
  Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. Aug, 2014  |   Pubmed ID: 25084178
• Iron in Multiple Sclerosis: Roles in Neurodegeneration and Repair
  Nature Reviews. Neurology. Aug, 2014  |   Pubmed ID: 25002107
• Understanding Disease Processes in Multiple Sclerosis Through Magnetic Resonance Imaging Studies in Animal Models
  NeuroImage. Clinical. 2014  |   Pubmed ID: 24936425
• Patrolling Monocytes Play a Critical Role in CX3CR1-mediated Neuroprotection During Excitotoxicity
  Brain Structure & Function. Apr, 2014  |   Pubmed ID: 24706067
• Remyelination After Spinal Cord Injury: is It a Target for Repair?
  Progress in Neurobiology. Jun, 2014  |   Pubmed ID: 24582777
• Toll-like Receptor 2-mediated Alternative Activation of Microglia is Protective After Spinal Cord Injury
  Brain : a Journal of Neurology. Mar, 2014  |   Pubmed ID: 24369381
• Therapeutic Activation of Macrophages and Microglia to Suppress Brain Tumor-initiating Cells
  Nature Neuroscience. Jan, 2014  |   Pubmed ID: 24316889
• Using Magnetic Resonance Imaging in Animal Models to Guide Drug Development in Multiple Sclerosis
  Multiple Sclerosis (Houndmills, Basingstoke, England). Jan, 2014  |   Pubmed ID: 24263386
• Active Inflammation Increases the Heterogeneity of MRI Texture in Mice with Relapsing Experimental Allergic Encephalomyelitis
  Magnetic Resonance Imaging. Feb, 2014  |   Pubmed ID: 24246391
• High-resolution Fluorescence Microscopy of Myelin Without Exogenous Probes
  NeuroImage. Feb, 2014  |   Pubmed ID: 24188810
• Therapeutic Activation of Macrophages and Microglia to Suppress Brain Tumor-initiating Cells
  Annals of Neurosciences. Oct, 2013  |   Pubmed ID: 25206040
• The Regulation of Reactive Changes Around Multiple Sclerosis Lesions by Phosphorylated Signal Transducer and Activator of Transcription
  Journal of Neuropathology and Experimental Neurology. Dec, 2013  |   Pubmed ID: 24226263
• Screening for Inhibitors of Microglia to Reduce Neuroinflammation
  CNS & Neurological Disorders Drug Targets. Sep, 2013  |   Pubmed ID: 24047520
• Pathophysiology of the Brain Extracellular Matrix: a New Target for Remyelination
  Nature Reviews. Neuroscience. Oct, 2013  |   Pubmed ID: 23985834
• Treatment Trials in Progressive MS--current Challenges and Future Directions
  Nature Reviews. Neurology. Sep, 2013  |   Pubmed ID: 23897406
• Reduction of Microglial Activity in a Model of Multiple Sclerosis by Dipyridamole
  Journal of Neuroinflammation. 2013  |   Pubmed ID: 23866809
• The Benefits and Detriments of Macrophages/microglia in Models of Multiple Sclerosis
  Clinical & Developmental Immunology. 2013  |   Pubmed ID: 23840244
• Association Between the Cerebral Inflammatory and Matrix Metalloproteinase Responses After Severe Traumatic Brain Injury in Humans
  Journal of Neurotrauma. Oct, 2013  |   Pubmed ID: 23799281
• Resistance to Oncolytic Myxoma Virus Therapy in Nf1(-/-)/trp53(-/-) Syngeneic Mouse Glioma Models is Independent of Anti-viral Type-I Interferon
  PloS One. 2013  |   Pubmed ID: 23762429
• A Prospective Evaluation of the Temporal Matrix Metalloproteinase Response After Severe Traumatic Brain Injury in Humans
  Journal of Neurotrauma. Oct, 2013  |   Pubmed ID: 23725031
• Extracellular Matrix Metalloproteinase Inducer Shows Active Perivascular Cuffs in Multiple Sclerosis
  Brain : a Journal of Neurology. Jun, 2013  |   Pubmed ID: 23687119
• Overcoming Neurite-inhibitory Chondroitin Sulfate Proteoglycans in the Astrocyte Matrix
  Glia. Jun, 2013  |   Pubmed ID: 23554135
• Reply: To PMID 23034914
  Annals of Neurology. Feb, 2013  |   Pubmed ID: 23424070
• Environmental Factors and Their Regulation of Immunity in Multiple Sclerosis
  Journal of the Neurological Sciences. Jan, 2013  |   Pubmed ID: 23154080
• Review: Endocrine Disrupting Chemicals and Immune Responses: a Focus on Bisphenol-A and Its Potential Mechanisms
  Molecular Immunology. Apr, 2013  |   Pubmed ID: 23123408
• Remyelination Therapy for Multiple Sclerosis
  Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Jan, 2013  |   Pubmed ID: 23070731
• Susceptibility-weighted Imaging in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Indicates Elevated Deoxyhemoglobin, Iron Deposition and Demyelination
  Multiple Sclerosis (Houndmills, Basingstoke, England). May, 2013  |   Pubmed ID: 23027879
• Prolactin in Multiple Sclerosis
  Multiple Sclerosis (Houndmills, Basingstoke, England). Jan, 2013  |   Pubmed ID: 22933621
• Cortical Remyelination: a New Target for Repair Therapies in Multiple Sclerosis
  Annals of Neurology. Dec, 2012  |   Pubmed ID: 23076662
• Chondroitin Sulfate Proteoglycans in Demyelinated Lesions Impair Remyelination
  Annals of Neurology. Sep, 2012  |   Pubmed ID: 23034914
• Immune Cell Infiltrates in Atypical Teratoid/rhabdoid Tumors
  The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. Sep, 2012  |   Pubmed ID: 22931701
• Kinetics of Proinflammatory Monocytes in a Model of Multiple Sclerosis and Its Perturbation by Laquinimod
  The American Journal of Pathology. Aug, 2012  |   Pubmed ID: 22749771
• Results of a Phase II Placebo-controlled Randomized Trial of Minocycline in Acute Spinal Cord Injury
  Brain : a Journal of Neurology. Apr, 2012  |   Pubmed ID: 22505632
• Lipocalin 2 is a Novel Immune Mediator of Experimental Autoimmune Encephalomyelitis Pathogenesis and is Modulated in Multiple Sclerosis
  Glia. Jul, 2012  |   Pubmed ID: 22499213
• A Novel Anti-EMMPRIN Function-blocking Antibody Reduces T Cell Proliferation and Neurotoxicity: Relevance to Multiple Sclerosis
  Journal of Neuroinflammation. 2012  |   Pubmed ID: 22480370
• A Dialog Between Glioma and Microglia That Promotes Tumor Invasiveness Through the CCL2/CCR2/interleukin-6 Axis
  Carcinogenesis. Feb, 2012  |   Pubmed ID: 22159219
• Chondroitin Sulphate Proteoglycans: Extracellular Matrix Proteins That Regulate Immunity of the Central Nervous System
  Autoimmunity Reviews. Oct, 2011  |   Pubmed ID: 21664302
• The Good, the Bad and the Ugly. Macrophages/microglia with a Focus on Myelin Repair
  Frontiers in Bioscience (Scholar Edition). Jun, 2011  |   Pubmed ID: 21622236
• Predominance of Th2 Polarization by Vitamin D Through a STAT6-dependent Mechanism
  Journal of Neuroinflammation. May, 2011  |   Pubmed ID: 21605467
• Analysis of the Mitochondrial Proteome in Multiple Sclerosis Cortex
  Biochimica Et Biophysica Acta. May, 2011  |   Pubmed ID: 21295140
• EMMPRIN: a Novel Regulator of Leukocyte Transmigration into the CNS in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2011  |   Pubmed ID: 21228176
• The Many Faces of EMMPRIN - Roles in Neuroinflammation
  Biochimica Et Biophysica Acta. Feb, 2011  |   Pubmed ID: 20674741
• [Promoting Remyelination by Reducing an Inhibitory Microenvironment]
  Rinsho Shinkeigaku = Clinical Neurology. Nov, 2010  |   Pubmed ID: 21921479
• Cleavage of Osteopontin by Matrix Metalloproteinase-12 Modulates Experimental Autoimmune Encephalomyelitis Disease in C57BL/6 Mice
  The American Journal of Pathology. Sep, 2010  |   Pubmed ID: 20651245
• Neuroinflammation and Demyelination in Multiple Sclerosis After Allogeneic Hematopoietic Stem Cell Transplantation
  Archives of Neurology. Jun, 2010  |   Pubmed ID: 20558390
• Reduction of PrP(C) in Human Cerebrospinal Fluid After Spinal Cord Injury
  Prion. 2010  |   Pubmed ID: 20418657
• Normal Human Monocytes Exposed to Glioma Cells Acquire Myeloid-derived Suppressor Cell-like Properties
  Neuro-oncology. Apr, 2010  |   Pubmed ID: 20308313
• Improving Outcomes of Neuroprotection by Minocycline: Guides from Cell Culture and Intracerebral Hemorrhage in Mice
  The American Journal of Pathology. Mar, 2010  |   Pubmed ID: 20110416
• The Interplay Between the Immune and Central Nervous Systems in Neuronal Injury
  Neurology. Jan, 2010  |   Pubmed ID: 20038767
• Reduction of Protein Kinase C Delta Attenuates Tenascin-C Stimulated Glioma Invasion in Three-dimensional Matrix
  Carcinogenesis. Feb, 2010  |   Pubmed ID: 19965895
• Taking Advantage of the Systemic Immune System to Cure Brain Diseases
  Neuron. Oct, 2009  |   Pubmed ID: 19840549
• Promoting Oligodendrogenesis and Myelin Repair Using the Multiple Sclerosis Medication Glatiramer Acetate
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2009  |   Pubmed ID: 19815532
• Multiexponential T2 and Magnetization Transfer MRI of Demyelination and Remyelination in Murine Spinal Cord
  NeuroImage. May, 2009  |   Pubmed ID: 19349232
• Matrix Metalloproteinase-12 Deficiency Worsens Relapsing-remitting Experimental Autoimmune Encephalomyelitis in Association with Cytokine and Chemokine Dysregulation
  The American Journal of Pathology. Mar, 2009  |   Pubmed ID: 19218336
• Depletion of Ly6G/Gr-1 Leukocytes After Spinal Cord Injury in Mice Alters Wound Healing and Worsens Neurological Outcome
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2009  |   Pubmed ID: 19158301
• Targeting MMPs in Acute and Chronic Neurological Conditions
  Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics. Oct, 2007  |   Pubmed ID: 17920539
• White Matter Plasticity and Enhanced Remyelination in the Maternal CNS
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2007  |   Pubmed ID: 17314279
• Myelin Formation During Development of the CNS is Delayed in Matrix Metalloproteinase-9 and -12 Null Mice
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2006  |   Pubmed ID: 16495447
• The Expression of Matrix Metalloproteinase-12 by Oligodendrocytes Regulates Their Maturation and Morphological Differentiation
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2004  |   Pubmed ID: 15342725
• P2X7-like Receptor Activation in Astrocytes Increases Chemokine Monocyte Chemoattractant Protein-1 Expression Via Mitogen-activated Protein Kinase
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2001  |   Pubmed ID: 11549724
• Metalloproteinases in Biology and Pathology of the Nervous System
  Nature Reviews. Neuroscience. Jul, 2001  |   Pubmed ID: 11433375
• Involvement of P21(Waf1/Cip1) in Protein Kinase C Alpha-induced Cell Cycle Progression
  Molecular and Cellular Biology. Jul, 2000  |   Pubmed ID: 10848585
• Matrix Metalloproteinase-9/gelatinase B is Required for Process Outgrowth by Oligodendrocytes
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 1999  |   Pubmed ID: 10493747