Vicky Garcia-Hernandez Department of Pathology, Michigan Medicine University of Michigan Biography Publications Institution JoVE Articles Vicky Garcia-Hernandez Dr. Vicky Garcia-Hernandez received her PhD degree in Cellular and Molecular Physiology from the Center for Research and Advanced Studies of the National Polytechnic Institute (CINVESTAV, Mexico) where she studied the regulation of claudins in the epithelia and she was an instructor in the National Polytechnic Institute (IPN) in Mexico City. Dr. Garcia-Hernandez is currently the lab manager and a Research Lab Specialist in the Parkos and Nusrat group. Her professional interests focus on the epithelia function and regulation, cellular signaling and physiopathology during inflammatory conditions. Her current projects include: A) role of stem cell factor (SCF) in regulation of intestinal mucosal homeostasis and repair after inflammation, and B) regulation of intercellular junctional proteins in the context of epithelial biology, barrier function and pathogenesis of mucosal inflammation in the gut. Publications Dysregulation of Intestinal Epithelial CFTR-dependent Cl Ion Transport and Paracellular Barrier Function Drives Gastrointestinal Symptoms of Food-induced Anaphylaxis in Mice Mucosal Immunology. 01, 2021 | Pubmed ID: 32576925 Desmocollin-2 Promotes Intestinal Mucosal Repair by Controlling Integrin-dependent Cell Adhesion and Migration Molecular Biology of the Cell. 03, 2020 | Pubmed ID: 31967937 Synthetic Hydrogels for Human Intestinal Organoid Generation and Colonic Wound Repair Nature Cell Biology. Nov, 2017 | Pubmed ID: 29058719 TNFα Promotes Mucosal Wound Repair Through Enhanced Platelet Activating Factor Receptor Signaling in the Epithelium Mucosal Immunology. Month, | Pubmed ID: 30971752 Macrophage-derived IL-10 Mediates Mucosal Repair by Epithelial WISP-1 Signaling The Journal of Clinical Investigation. Month, | Pubmed ID: 28783045 Intestinal Epithelial Claudins: Expression and Regulation in Homeostasis and Inflammation Annals of the New York Academy of Sciences. Month, | Pubmed ID: 28493289 Systematische Scoring-Analyse für Darmentzündungen in einem Murine Dextran Natriumsulfat-induzierte Colitis Modell Vicky Garcia-Hernandez1, Philipp-Alexander Neumann2, Stefan Koch3,4, Renae Lyons1, Asma Nusrat1, Charles A. Parkos1 1Department of Pathology, University of Michigan, 2Department of Surgery, Klinikum Rechts der Isar, Technische Universität München, 3Wallenberg Centre for Molecular Medicine, Linköping University, 4Department of Biomedical and Clinical Sciences (BKV), Linköping University JoVE 62135 Immunologie et Infection
Systematische Scoring-Analyse für Darmentzündungen in einem Murine Dextran Natriumsulfat-induzierte Colitis Modell Vicky Garcia-Hernandez1, Philipp-Alexander Neumann2, Stefan Koch3,4, Renae Lyons1, Asma Nusrat1, Charles A. Parkos1 1Department of Pathology, University of Michigan, 2Department of Surgery, Klinikum Rechts der Isar, Technische Universität München, 3Wallenberg Centre for Molecular Medicine, Linköping University, 4Department of Biomedical and Clinical Sciences (BKV), Linköping University JoVE 62135 Immunologie et Infection