Vladimir I. Titorenko Department of Biology Concordia University Biography Publications Institution JoVE Articles Vladimir I. Titorenko has not added a biography. If you are Vladimir I. Titorenko and would like to personalize this page please email our Author Liaison for assistance. Publications Mechanisms That Link Chronological Aging to Cellular Quiescence in Budding Yeast International Journal of Molecular Sciences. Jul, 2020 | Pubmed ID: 32630624 Discovery of Fifteen New Geroprotective Plant Extracts and Identification of Cellular Processes They Affect to Prolong the Chronological Lifespan of Budding Yeast Oncotarget. Jun, 2020 | Pubmed ID: 32577164 Mechanisms by Which PE21, an Extract from the White Willow , Delays Chronological Aging in Budding Yeast Oncotarget. Oct, 2019 | Pubmed ID: 31645900 Aging and Age-related Disorders: From Molecular Mechanisms to Therapies International Journal of Molecular Sciences. Jul, 2019 | Pubmed ID: 31277345 Mechanisms Through Which Some Mitochondria-Generated Metabolites Act As Second Messengers That Are Essential Contributors to the Aging Process in Eukaryotes Across Phyla Frontiers in Physiology. 2019 | Pubmed ID: 31057428 Quiescence Entry, Maintenance, and Exit in Adult Stem Cells International Journal of Molecular Sciences. May, 2019 | Pubmed ID: 31052375 Pairwise Combinations of Chemical Compounds That Delay Yeast Chronological Aging Through Different Signaling Pathways Display Synergistic Effects on the Extent of Aging Delay Oncotarget. Jan, 2019 | Pubmed ID: 30719227 Mechanisms Through Which Lithocholic Acid Delays Yeast Chronological Aging Under Caloric Restriction Conditions Oncotarget. Oct, 2018 | Pubmed ID: 30405886 Molecular and Cellular Mechanisms of Aging and Age-related Disorders International Journal of Molecular Sciences. Jul, 2018 | Pubmed ID: 30011889 Yeast Chronological Aging is Linked to Cell Cycle Regulation Cell Cycle (Georgetown, Tex.). 2018 | Pubmed ID: 29895227 Caloric Restriction Delays Yeast Chronological Aging by Remodeling Carbohydrate and Lipid Metabolism, Altering Peroxisomal and Mitochondrial Functionalities, and Postponing the Onsets of Apoptotic and Liponecrotic Modes of Regulated Cell Death Oncotarget. Mar, 2018 | Pubmed ID: 29662634 Yeast Cells Exposed to Exogenous Palmitoleic Acid Either Adapt to Stress and Survive or Commit to Regulated Liponecrosis and Die Oxidative Medicine and Cellular Longevity. 2018 | Pubmed ID: 29636840 Some Metabolites Act As Second Messengers in Yeast Chronological Aging International Journal of Molecular Sciences. Mar, 2018 | Pubmed ID: 29543708 Lipid Metabolism and Transport Define Longevity of the Yeast Saccharomyces Cerevisiae Frontiers in Bioscience (Landmark Edition). Jan, 2018 | Pubmed ID: 28930594 Caloric Restriction Extends Yeast Chronological Lifespan Via a Mechanism Linking Cellular Aging to Cell Cycle Regulation, Maintenance of a Quiescent State, Entry into a Non-quiescent State and Survival in the Non-quiescent State Oncotarget. Sep, 2017 | Pubmed ID: 29050207 Diindolylmethane and Its Halogenated Derivatives Induce Protective Autophagy in Human Prostate Cancer Cells Via Induction of the Oncogenic Protein AEG-1 and Activation of AMP-activated Protein Kinase (AMPK) Cellular Signalling. 12, 2017 | Pubmed ID: 28923415 Mechanisms Underlying the Essential Role of Mitochondrial Membrane Lipids in Yeast Chronological Aging Oxidative Medicine and Cellular Longevity. 2017 | Pubmed ID: 28593023 Specific Changes in Mitochondrial Lipidome Alter Mitochondrial Proteome and Increase the Geroprotective Efficiency of Lithocholic Acid in Chronologically Aging Yeast Oncotarget. May, 2017 | Pubmed ID: 28410198 A Laboratory Test of Evolutionary Aging Theories Aging. 03, 2017 | Pubmed ID: 28325887 Empirical Validation of a Hypothesis of the Hormetic Selective Forces Driving the Evolution of Longevity Regulation Mechanisms Frontiers in Genetics. 2016 | Pubmed ID: 27999589 Lithocholic Acid Induces Endoplasmic Reticulum Stress, Autophagy and Mitochondrial Dysfunction in Human Prostate Cancer Cells PeerJ. 2016 | Pubmed ID: 27896021 Empirical Verification of Evolutionary Theories of Aging Aging. 10, 2016 | Pubmed ID: 27783562 Communications Between Mitochondria, the Nucleus, Vacuoles, Peroxisomes, the Endoplasmic Reticulum, the Plasma Membrane, Lipid Droplets, and the Cytosol During Yeast Chronological Aging Frontiers in Genetics. 2016 | Pubmed ID: 27729926 Six Plant Extracts Delay Yeast Chronological Aging Through Different Signaling Pathways Oncotarget. Aug, 2016 | Pubmed ID: 27447556 Mitochondria Operate As Signaling Platforms in Yeast Aging Aging. Feb, 2016 | Pubmed ID: 26928478 Discovery of Plant Extracts That Greatly Delay Yeast Chronological Aging and Have Different Effects on Longevity-defining Cellular Processes Oncotarget. Mar, 2016 | Pubmed ID: 26918729 Cell-Nonautonomous Mechanisms Underlying Cellular and Organismal Aging International Review of Cell and Molecular Biology. 2016 | Pubmed ID: 26811290 Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition) Autophagy. Jan, 2016 | Pubmed ID: 26799652 A Novel Approach to the Discovery of Anti-tumor Pharmaceuticals: Searching for Activators of Liponecrosis Oncotarget. Feb, 2016 | Pubmed ID: 26636650 Longevity Extension by Phytochemicals Molecules (Basel, Switzerland). Apr, 2015 | Pubmed ID: 25871373 Lithocholic Bile Acid Accumulated in Yeast Mitochondria Orchestrates a Development of an Anti-aging Cellular Pattern by Causing Age-related Changes in Cellular Proteome Cell Cycle (Georgetown, Tex.). 2015 | Pubmed ID: 25839782 Mechanisms by Which Different Functional States of Mitochondria Define Yeast Longevity International Journal of Molecular Sciences. Mar, 2015 | Pubmed ID: 25768339 The Intricate Interplay Between Mechanisms Underlying Aging and Cancer Aging and Disease. Feb, 2015 | Pubmed ID: 25657853 Cell-autonomous Mechanisms of Chronological Aging in the Yeast Microbial Cell (Graz, Austria). May, 2014 | Pubmed ID: 28357241 Origin and Spatiotemporal Dynamics of the Peroxisomal Endomembrane System Frontiers in Physiology. 2014 | Pubmed ID: 25566090 Quasi-programmed Aging of Budding Yeast: a Trade-off Between Programmed Processes of Cell Proliferation, Differentiation, Stress Response, Survival and Death Defines Yeast Lifespan Cell Cycle (Georgetown, Tex.). 2014 | Pubmed ID: 25485579 Mechanism of Liponecrosis, a Distinct Mode of Programmed Cell Death Cell Cycle (Georgetown, Tex.). 2014 | Pubmed ID: 25483081 Mechanisms Underlying the Anti-aging and Anti-tumor Effects of Lithocholic Bile Acid International Journal of Molecular Sciences. Sep, 2014 | Pubmed ID: 25238416 Metabolomic and Lipidomic Analyses of Chronologically Aging Yeast Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 25213255 A Mitochondrially Targeted Compound Delays Aging in Yeast Through a Mechanism Linking Mitochondrial Membrane Lipid Metabolism to Mitochondrial Redox Biology Redox Biology. 2014 | Pubmed ID: 24563847 Cells with Impaired Mitochondrial H2O2 Sensing Generate Less •OH Radicals and Live Longer Antioxidants & Redox Signaling. Oct, 2014 | Pubmed ID: 24382195 Macromitophagy, Neutral Lipids Synthesis, and Peroxisomal Fatty Acid Oxidation Protect Yeast from "liponecrosis", a Previously Unknown Form of Programmed Cell Death Cell Cycle (Georgetown, Tex.). 2014 | Pubmed ID: 24196447 Bile Acids Induce Apoptosis Selectively in Androgen-dependent and -independent Prostate Cancer Cells PeerJ. 2013 | Pubmed ID: 23940835 Mitochondrial Membrane Lipidome Defines Yeast Longevity Aging. Jul, 2013 | Pubmed ID: 23924582 Essential Roles of Peroxisomally Produced and Metabolized Biomolecules in Regulating Yeast Longevity Sub-cellular Biochemistry. 2013 | Pubmed ID: 23821148 A Network of Interorganellar Communications Underlies Cellular Aging IUBMB Life. Aug, 2013 | Pubmed ID: 23818261 Macromitophagy is a Longevity Assurance Process That in Chronologically Aging Yeast Limited in Calorie Supply Sustains Functional Mitochondria and Maintains Cellular Lipid Homeostasis Aging. Apr, 2013 | Pubmed ID: 23553280 The Spatiotemporal Dynamics of Longevity-defining Cellular Processes and Its Modulation by Genetic, Dietary, and Pharmacological Anti-aging Interventions Frontiers in Physiology. 2012 | Pubmed ID: 23118730 Integration of Peroxisomes into an Endomembrane System That Governs Cellular Aging Frontiers in Physiology. 2012 | Pubmed ID: 22936916 Lithocholic Acid Extends Longevity of Chronologically Aging Yeast Only if Added at Certain Critical Periods of Their Lifespan Cell Cycle (Georgetown, Tex.). Sep, 2012 | Pubmed ID: 22894934 Caloric Restriction Extends Yeast Chronological Lifespan by Altering a Pattern of Age-related Changes in Trehalose Concentration Frontiers in Physiology. 2012 | Pubmed ID: 22783207 Interspecies Chemical Signals Released into the Environment May Create Xenohormetic, Hormetic and Cytostatic Selective Forces That Drive the Ecosystemic Evolution of Longevity Regulation Mechanisms Dose-response : a Publication of International Hormesis Society. 2012 | Pubmed ID: 22423230 Dynamics and Regulation of Lipid Droplet Formation in Lipopolysaccharide (LPS)-stimulated Microglia Biochimica Et Biophysica Acta. Jan, 2012 | Pubmed ID: 22289388 Lithocholic Bile Acid Selectively Kills Neuroblastoma Cells, While Sparing Normal Neuronal Cells Oncotarget. Oct, 2011 | Pubmed ID: 21992775 In Search of Housekeeping Pathways That Regulate Longevity Cell Cycle (Georgetown, Tex.). Sep, 2011 | Pubmed ID: 21862878 Peroxisome Metabolism and Cellular Aging Traffic (Copenhagen, Denmark). Mar, 2011 | Pubmed ID: 21083858 Xenohormetic, Hormetic and Cytostatic Selective Forces Driving Longevity at the Ecosystemic Level Aging. Aug, 2010 | Pubmed ID: 20693605 Chemical Genetic Screen Identifies Lithocholic Acid As an Anti-aging Compound That Extends Yeast Chronological Life Span in a TOR-independent Manner, by Modulating Housekeeping Longevity Assurance Processes Aging. Jul, 2010 | Pubmed ID: 20622262 A Novel Function of Lipid Droplets in Regulating Longevity Biochemical Society Transactions. Oct, 2009 | Pubmed ID: 19754450 Effect of Calorie Restriction on the Metabolic History of Chronologically Aging Yeast Experimental Gerontology. Sep, 2009 | Pubmed ID: 19539741 Spatiotemporal Dynamics of the ER-derived Peroxisomal Endomembrane System International Review of Cell and Molecular Biology. 2009 | Pubmed ID: 19121819 A Signal from Inside the Peroxisome Initiates Its Division by Promoting the Remodeling of the Peroxisomal Membrane The Journal of Cell Biology. Apr, 2007 | Pubmed ID: 17438077 Overproduction of Translation Elongation Factor 1-alpha (eEF1A) Suppresses the Peroxisome Biogenesis Defect in a Hansenula Polymorpha Pex3 Mutant Via Translational Read-through FEMS Yeast Research. Oct, 2007 | Pubmed ID: 17425673 Lipids and Lipid Domains in the Peroxisomal Membrane of the Yeast Yarrowia Lipolytica Biochimica Et Biophysica Acta. Dec, 2006 | Pubmed ID: 17023063 Peroxisome Biogenesis: the Peroxisomal Endomembrane System and the Role of the ER The Journal of Cell Biology. Jul, 2006 | Pubmed ID: 16801391 Dynamic Ergosterol- and Ceramide-rich Domains in the Peroxisomal Membrane Serve As an Organizing Platform for Peroxisome Fusion The Journal of Cell Biology. Feb, 2005 | Pubmed ID: 15738267 A New Definition for the Consensus Sequence of the Peroxisome Targeting Signal Type 2 Journal of Molecular Biology. Jul, 2004 | Pubmed ID: 15312767 The Peroxisome: Orchestrating Important Developmental Decisions from Inside the Cell The Journal of Cell Biology. Mar, 2004 | Pubmed ID: 14981090 Peroxisome Division in the Yeast Yarrowia Lipolytica is Regulated by a Signal from Inside the Peroxisome The Journal of Cell Biology. Sep, 2003 | Pubmed ID: 14504266 RNA Interference of Peroxisome-related Genes in C. Elegans: a New Model for Human Peroxisomal Disorders Physiological Genomics. Aug, 2002 | Pubmed ID: 12181365 Acyl-CoA Oxidase is Imported As a Heteropentameric, Cofactor-containing Complex into Peroxisomes of Yarrowia Lipolytica The Journal of Cell Biology. Feb, 2002 | Pubmed ID: 11815635 Sıvı KromatografiSi Kullanan Saccharomyces Cerevisiae'nin Nicel Metabolomikleri Tandem Kütle Spektrometresi ile Birleştiğinde Karamat Mohammad1, Heng Jiang2, Vladimir I. Titorenko1 1Department of Biology, Concordia University, 2Centre for Biological Applications of Mass Spectrometry, Concordia University JoVE 62061 Biochimie Tandem Kütle Spektrometresi Ile Birleşen Sıvı Kromatografi kullanarak Saccharomyces Cerevisiae'nin Hücresel Lipidomukan Analizi Karamat Mohammad1, Heng Jiang2, Md. Israil Hossain1, Vladimir I. Titorenko1 1Department of Biology, Concordia University, 2Department of Chemistry and Biochemistry, Centre for Biological Applications of Mass Spectrometry, Concordia University JoVE 60616 Biochimie Maya hücreleri Mitokondri saflaştırılması Christopher Gregg1, Pavlo Kyryakov1, Vladimir I. Titorenko1 1Department of Biology, Concordia University JoVE 1417 Biologie Nicel Değerlendirme Elektrosprey İyonizasyon Kütle Spektrometresi kullanarak Maya Lipidome Simon D. Bourque1, Vladimir I. Titorenko1 1Department of Biology, Concordia University JoVE 1513 Biologie
Sıvı KromatografiSi Kullanan Saccharomyces Cerevisiae'nin Nicel Metabolomikleri Tandem Kütle Spektrometresi ile Birleştiğinde Karamat Mohammad1, Heng Jiang2, Vladimir I. Titorenko1 1Department of Biology, Concordia University, 2Centre for Biological Applications of Mass Spectrometry, Concordia University JoVE 62061 Biochimie
Tandem Kütle Spektrometresi Ile Birleşen Sıvı Kromatografi kullanarak Saccharomyces Cerevisiae'nin Hücresel Lipidomukan Analizi Karamat Mohammad1, Heng Jiang2, Md. Israil Hossain1, Vladimir I. Titorenko1 1Department of Biology, Concordia University, 2Department of Chemistry and Biochemistry, Centre for Biological Applications of Mass Spectrometry, Concordia University JoVE 60616 Biochimie
Maya hücreleri Mitokondri saflaştırılması Christopher Gregg1, Pavlo Kyryakov1, Vladimir I. Titorenko1 1Department of Biology, Concordia University JoVE 1417 Biologie
Nicel Değerlendirme Elektrosprey İyonizasyon Kütle Spektrometresi kullanarak Maya Lipidome Simon D. Bourque1, Vladimir I. Titorenko1 1Department of Biology, Concordia University JoVE 1513 Biologie