Wen Bu Lester & Sue Smith Breast Center Baylor College of Medicine Biography Publications Institution JoVE Articles Wen Bu has not added a biography. If you are Wen Bu and would like to personalize this page please email our Author Liaison for assistance. Publications Short-term PI3K Inhibition Prevents Breast Cancer in Preclinical Models Cancer Prevention Research (Philadelphia, Pa.). Feb, 2023 | Pubmed ID: 36343340 High-throughput Profiling of Histone Post-translational Modifications and Chromatin Modifying Proteins by Reverse Phase Protein Array Journal of Proteomics. Jun, 2022 | Pubmed ID: 35489683 Targeting the Pro-survival Protein BCL-2 to Prevent Breast Cancer Cancer Prevention Research (Philadelphia, Pa.). Jan, 2022 | Pubmed ID: 34667127 Intraductal Injection of Lentivirus Vectors for Stably Introducing Genes into Rat Mammary Epithelial Cells in Vivo Journal of Mammary Gland Biology and Neoplasia. Dec, 2020 | Pubmed ID: 33165800 Immuno-subtyping of Breast Cancer Reveals Distinct Myeloid Cell Profiles and Immunotherapy Resistance Mechanisms Nature Cell Biology. 09, 2019 | Pubmed ID: 31451770 Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes Cancer Research. 01, 2019 | Pubmed ID: 30401712 Pharmacological Targeting of MYC-regulated IRE1/XBP1 Pathway Suppresses MYC-driven Breast Cancer The Journal of Clinical Investigation. 04, 2018 | Pubmed ID: 29480818 Breast Tumor Cell-specific Knockout of Inhibits Cancer Cell Plasticity, Dissemination, and Lung Metastasis in Mice Proceedings of the National Academy of Sciences of the United States of America. Oct, 2017 | Pubmed ID: 29073077 Targeting Oncogenes into a Defined Subset of Mammary Cells Demonstrates That the Initiating Oncogenic Mutation Defines the Resulting Tumor Phenotype International Journal of Biological Sciences. 2016 | Pubmed ID: 27019623 Luminal Epithelial Cells Within the Mammary Gland Can Produce Basal Cells Upon Oncogenic Stress Oncogene. Mar, 2016 | Pubmed ID: 26096929 Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion Via JAK2 Activation Cell Reports. Jul, 2015 | Pubmed ID: 26166574 Krt6a-positive Mammary Epithelial Progenitors Are Not at Increased Vulnerability to Tumorigenesis Initiated by ErbB2 PloS One. 2015 | Pubmed ID: 25635772 STAT3 Signaling is Activated Preferentially in Tumor-initiating Cells in Claudin-low Models of Human Breast Cancer Stem Cells (Dayton, Ohio). Oct, 2014 | Pubmed ID: 24891218 Wnt-responsive Cancer Stem Cells Are Located Close to Distorted Blood Vessels and Not in Hypoxic Regions in a P53-null Mouse Model of Human Breast Cancer Stem Cells Translational Medicine. Jul, 2014 | Pubmed ID: 24797826 Amplification and Over-expression of MAP3K3 Gene in Human Breast Cancer Promotes Formation and Survival of Breast Cancer Cells The Journal of Pathology. Jan, 2014 | Pubmed ID: 24122835 Mammary Cells with Active Wnt Signaling Resist ErbB2-induced Tumorigenesis PloS One. 2013 | Pubmed ID: 24265712 Differential Regulation of C-Jun Protein Plays an Instrumental Role in Chemoresistance of Cancer Cells The Journal of Biological Chemistry. Jul, 2013 | Pubmed ID: 23678002 A Novel Role of Hematopoietic CCL5 in Promoting Triple-negative Mammary Tumor Progression by Regulating Generation of Myeloid-derived Suppressor Cells Cell Research. Mar, 2013 | Pubmed ID: 23266888 EGFR-induced and PKCε Monoubiquitylation-dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis Molecular Cell. Dec, 2012 | Pubmed ID: 23123196 Keratin 6a Marks Mammary Bipotential Progenitor Cells That Can Give Rise to a Unique Tumor Model Resembling Human Normal-like Breast Cancer Oncogene. Oct, 2011 | Pubmed ID: 21532625 Defining the ATM-mediated Barrier to Tumorigenesis in Somatic Mammary Cells Following ErbB2 Activation Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 20133707 Lentivirus Vectors for Stably Introducing Genes into Mammary Epithelial Cells in Vivo Journal of Mammary Gland Biology and Neoplasia. Dec, 2009 | Pubmed ID: 19936990 Lentivirus-mediated Oncogene Introduction into Mammary Cells in Vivo Induces Tumors Neoplasia (New York, N.Y.). Jul, 2008 | Pubmed ID: 18592025 Keratin 6 is Not Essential for Mammary Gland Development Breast Cancer Research : BCR. 2006 | Pubmed ID: 16790075 体内 通过乳腺导管内注射将基因传递到小鼠乳腺上皮细胞 Wen Bu1,2, Yi Li1,3 1Lester & Sue Smith Breast Center, Baylor College of Medicine, 2Department of Medicine, Baylor College of Medicine, 3Department of Molecular & Cellular Biology, Baylor College of Medicine, Houston, TX 77030 JoVE 64718 Recherche en cancérologie
体内 通过乳腺导管内注射将基因传递到小鼠乳腺上皮细胞 Wen Bu1,2, Yi Li1,3 1Lester & Sue Smith Breast Center, Baylor College of Medicine, 2Department of Medicine, Baylor College of Medicine, 3Department of Molecular & Cellular Biology, Baylor College of Medicine, Houston, TX 77030 JoVE 64718 Recherche en cancérologie