Yanhua Hu Cardiovascular Division King's College London BHF Centre Biography Publications Institution JoVE Articles Yanhua Hu has not added a biography. If you are Yanhua Hu and would like to personalize this page please email our Author Liaison for assistance. Publications MicroRNA-199b Modulates Vascular Cell Fate During IPS Cell Differentiation by Targeting the Notch Ligand Jagged1 and Enhancing VEGF Signaling Stem Cells (Dayton, Ohio). Dec, 2014 | Pubmed ID: 25535084 Unspliced X-box-binding Protein 1 (XBP1) Protects Endothelial Cells from Oxidative Stress Through Interaction with Histone Deacetylase 3 The Journal of Biological Chemistry. Oct, 2014 | Pubmed ID: 25190803 Bidirectional Cross-regulation Between the Endothelial Nitric Oxide Synthase and β-catenin Signalling Pathways Cardiovascular Research. Oct, 2014 | Pubmed ID: 25062958 Stem Cells Accumulate on a Decellularized Arterial Xenograft In vivo The Annals of Thoracic Surgery. Jun, 2014 | Pubmed ID: 24725834 Macrophages Control Vascular Stem/progenitor Cell Plasticity Through Tumor Necrosis Factor-α-mediated Nuclear Factor-κB Activation Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2014 | Pubmed ID: 24458710 Endothelial Lineage Differentiation from Induced Pluripotent Stem Cells is Regulated by MicroRNA-21 and Transforming Growth Factor β2 (TGF-β2) Pathways The Journal of Biological Chemistry. Feb, 2014 | Pubmed ID: 24356956 Matrix Metalloproteinase-8 Promotes Vascular Smooth Muscle Cell Proliferation and Neointima Formation Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2014 | Pubmed ID: 24158518 Histone Deacetylase 3 Unconventional Splicing Mediates Endothelial-to-mesenchymal Transition Through Transforming Growth Factor β2 The Journal of Biological Chemistry. Nov, 2013 | Pubmed ID: 24045946 Tetrahydrobiopterin Determines Vascular Remodeling Through Enhanced Endothelial Cell Survival and Regeneration Circulation. Sep, 2013 | Pubmed ID: 24030421 Dysfunction of Endothelial Progenitor Cells from Smokers and Chronic Obstructive Pulmonary Disease Patients Due to Increased DNA Damage and Senescence Stem Cells (Dayton, Ohio). Dec, 2013 | Pubmed ID: 23897750 Adventitial Stem Cells in Vein Grafts Display Multilineage Potential That Contributes to Neointimal Formation Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2013 | Pubmed ID: 23744989 Allogeneic Bone Marrow-derived Mesenchymal Stem Cells Attenuate Hepatic Ischemia-reperfusion Injury by Suppressing Oxidative Stress and Inhibiting Apoptosis in Rats International Journal of Molecular Medicine. Jun, 2013 | Pubmed ID: 23589072 Vascular Endothelial Cell Growth-activated XBP1 Splicing in Endothelial Cells is Crucial for Angiogenesis Circulation. Apr, 2013 | Pubmed ID: 23529610 Smooth Muscle Cells Differentiated from Reprogrammed Embryonic Lung Fibroblasts Through DKK3 Signaling Are Potent for Tissue Engineering of Vascular Grafts Circulation Research. May, 2013 | Pubmed ID: 23529184 XBP1 MRNA Splicing Triggers an Autophagic Response in Endothelial Cells Through BECLIN-1 Transcriptional Activation The Journal of Biological Chemistry. Jan, 2013 | Pubmed ID: 23184933 Direct Reprogramming of Fibroblasts into Endothelial Cells Capable of Angiogenesis and Reendothelialization in Tissue-engineered Vessels Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22869753 Contribution of Stem Cells to Neointimal Formation of Decellularized Vessel Grafts in a Novel Mouse Model The American Journal of Pathology. May, 2012 | Pubmed ID: 22613026 A Templated Method to Bi2WO6 Hollow Microspheres and Their Conversion to Double-shell Bi2O3/Bi2WO6 Hollow Microspheres with Improved Photocatalytic Performance Inorganic Chemistry. May, 2012 | Pubmed ID: 22591138 Nrf3-Pla2g7 Interaction Plays an Essential Role in Smooth Muscle Cell Differentiation From Stem Cells Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2012 | Pubmed ID: 22247257 Galectin-9 Protein Expression in Endothelial Cells is Positively Regulated by Histone Deacetylase 3 The Journal of Biological Chemistry. Dec, 2011 | Pubmed ID: 22027828 Splicing of Histone Deacetylase 7 Modulates Smooth Muscle Cell Proliferation and Neointima Formation Through Nuclear β-catenin Translocation Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2011 | Pubmed ID: 21836063 Adventitial Biology: Differentiation and Function Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2011 | Pubmed ID: 21677295 Topical HDL Administration Reduces Vein Graft Atherosclerosis in Apo E Deficient Mice Atherosclerosis. Feb, 2011 | Pubmed ID: 20943224 Protein Kinase C{delta} Deficiency Accelerates Neointimal Lesions of Mouse Injured Artery Involving Delayed Reendothelialization and Vasohibin-1 Accumulation Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2010 | Pubmed ID: 20884873 Phosphorylation of Threonine 154 in P40phox is an Important Physiological Signal for Activation of the Neutrophil NADPH Oxidase Blood. Dec, 2010 | Pubmed ID: 20861461 Different Effects of Angiotensin II and Angiotensin-(1-7) on Vascular Smooth Muscle Cell Proliferation and Migration PloS One. 2010 | Pubmed ID: 20808802 Automated Analysis of Protein Subcellular Location in Time Series Images Bioinformatics (Oxford, England). Jul, 2010 | Pubmed ID: 20484328 Increased Sensitivity of HIV Variants Selected by Attachment Inhibitors to Broadly Neutralizing Antibodies Virology. Jul, 2010 | Pubmed ID: 20400170 Histone Deacetylase 7 Controls Endothelial Cell Growth Through Modulation of Beta-catenin Circulation Research. Apr, 2010 | Pubmed ID: 20224040 Crucial Role of Nrf3 in Smooth Muscle Cell Differentiation from Stem Cells Circulation Research. Mar, 2010 | Pubmed ID: 20093628 Histone Deacetylase 3 is Critical in Endothelial Survival and Atherosclerosis Development in Response to Disturbed Flow Circulation. Jan, 2010 | Pubmed ID: 20026773 A Role of Matrix Metalloproteinase-8 in Atherosclerosis Circulation Research. Oct, 2009 | Pubmed ID: 19745165 Sustained Activation of XBP1 Splicing Leads to Endothelial Apoptosis and Atherosclerosis Development in Response to Disturbed Flow Proceedings of the National Academy of Sciences of the United States of America. May, 2009 | Pubmed ID: 19416856 Splicing of HDAC7 Modulates the SRF-myocardin Complex During Stem-cell Differentiation Towards Smooth Muscle Cells Journal of Cell Science. Feb, 2009 | Pubmed ID: 19174469 A Comparative Assessment of the Efficacy of Carbomer Gel and Carboxymethyl Cellulose Containing Artificial Tears in Dry Eyes Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. Oct, 2008 | Pubmed ID: 18846346 Proteomic and Metabolomic Analysis of Smooth Muscle Cells Derived from the Arterial Media and Adventitial Progenitors of Apolipoprotein E-deficient Mice Circulation Research. May, 2008 | Pubmed ID: 18388323 Rapid Endothelial Turnover in Atherosclerosis-prone Areas Coincides with Stem Cell Repair in Apolipoprotein E-deficient Mice Circulation. Apr, 2008 | Pubmed ID: 18378610 Vessel Graft Atherosclerosis in Murine Models Current Drug Targets. Mar, 2008 | Pubmed ID: 18336243 Endothelial Progenitor Cells, Cardiovascular Risk Factors, Cytokine Levels and Atherosclerosis--results from a Large Population-based Study PloS One. 2007 | Pubmed ID: 17925881 Lacking Cytokine Production in ES Cells and ES-cell-derived Vascular Cells Stimulated by TNF-alpha is Rescued by HDAC Inhibitor Trichostatin A American Journal of Physiology. Cell Physiology. Oct, 2007 | Pubmed ID: 17626239 Increased In-stent Stenosis in ApoE Knockout Mice: Insights from a Novel Mouse Model of Balloon Angioplasty and Stenting Arteriosclerosis, Thrombosis, and Vascular Biology. Apr, 2007 | Pubmed ID: 17204666 Stem Cell-derived Sca-1+ Progenitors Differentiate into Smooth Muscle Cells, Which is Mediated by Collagen IV-integrin Alpha1/beta1/alphav and PDGF Receptor Pathways American Journal of Physiology. Cell Physiology. Jan, 2007 | Pubmed ID: 16914533 Resection and Cryotherapy Combined with Amniotic Membrane Transplantation for the Treatment of Vernal Keratoconjunctivitis with Giant Papillae Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 2006 | Pubmed ID: 17219985 Effects of ShRNA Targeting Survivin on Apoptosis of Human Retinoblastoma Cell Line Hxo-rb44 in Vitro Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 2006 | Pubmed ID: 17219984 HDAC3 is Crucial in Shear- and VEGF-induced Stem Cell Differentiation Toward Endothelial Cells The Journal of Cell Biology. Sep, 2006 | Pubmed ID: 16982804 Effects of CTLA4-Ig Gene-modified Dendritic Cells on the Corneal Allografts Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 2006 | Pubmed ID: 16961296 Sca-1+ Progenitors Derived from Embryonic Stem Cells Differentiate into Endothelial Cells Capable of Vascular Repair After Arterial Injury Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2006 | Pubmed ID: 16902164 Lymphangiogenesis Occurring in Transplanted Corneas Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 2006 | Pubmed ID: 16850758 TLR4 Expression in Mouse Embryonic Stem Cells and in Stem Cell-derived Vascular Cells is Regulated by Epigenetic Modifications Biochemical and Biophysical Research Communications. Aug, 2006 | Pubmed ID: 16814255 Central Corneal Thickness in Adult Chinese Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 2006 | Pubmed ID: 16711030 Accelerated Arteriosclerosis of Vein Grafts in Inducible NO Synthase(-/-) Mice is Related to Decreased Endothelial Progenitor Cell Repair Circulation Research. Feb, 2006 | Pubmed ID: 16385078 Gene Transfer of a Broad Spectrum CC-chemokine Inhibitor Reduces Vein Graft Atherosclerosis in Apolipoprotein E-knockout Mice Circulation. Aug, 2005 | Pubmed ID: 16159823 Proteomic and Metabolomic Analyses of Atherosclerotic Vessels from Apolipoprotein E-deficient Mice Reveal Alterations in Inflammation, Oxidative Stress, and Energy Metabolism Arteriosclerosis, Thrombosis, and Vascular Biology. Oct, 2005 | Pubmed ID: 16123314 Ipsilateral Lymphadenectomy to Inhibit Corneal Allograft Rejection in Rats Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 2005 | Pubmed ID: 15934318 Adventitial Progenitor Cells Contribute to Arteriosclerosis Trends in Cardiovascular Medicine. Feb, 2005 | Pubmed ID: 15885572 Biomechanical Stress Induces IL-6 Expression in Smooth Muscle Cells Via Ras/Rac1-p38 MAPK-NF-kappaB Signaling Pathways American Journal of Physiology. Heart and Circulatory Physiology. Jun, 2005 | Pubmed ID: 15681696 Expression of VEGF-C in Rat Cornea After Alkali Injury Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 2004 | Pubmed ID: 15641699 Ischemic Preconditioning Exaggerates Cardiac Damage in PKC-delta Null Mice American Journal of Physiology. Heart and Circulatory Physiology. Aug, 2004 | Pubmed ID: 15277209 Automated Interpretation of Subcellular Patterns from Immunofluorescence Microscopy Journal of Immunological Methods. Jul, 2004 | Pubmed ID: 15261574 Abundant Progenitor Cells in the Adventitia Contribute to Atherosclerosis of Vein Grafts in ApoE-deficient Mice The Journal of Clinical Investigation. May, 2004 | Pubmed ID: 15124016 Thrombosis and Neointima Formation in Vein Grafts Are Inhibited by Locally Applied Aspirin Through Endothelial Protection Circulation Research. Jun, 2004 | Pubmed ID: 15117816 Endothelial Replacement and Angiogenesis in Arteriosclerotic Lesions of Allografts Are Contributed by Circulating Progenitor Cells Circulation. Dec, 2003 | Pubmed ID: 14656919 Circulating Progenitor Cells Regenerate Endothelium of Vein Graft Atherosclerosis, Which is Diminished in ApoE-deficient Mice Circulation Research. Oct, 2003 | Pubmed ID: 14512446 Mechanical Stress-activated PKCdelta Regulates Smooth Muscle Cell Migration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Nov, 2003 | Pubmed ID: 12958154 Activation of Heat Shock Transcription Factor 1 in Atherosclerosis The American Journal of Pathology. May, 2003 | Pubmed ID: 12707051 New Mouse Model of Vein Bypass Graft Atherosclerosis Heart, Lung & Circulation. 2002 | Pubmed ID: 16352095 The Expression of the Plasmid DNA Encoding TGF-beta 1 in Endothelium After Injection into the Anterior Chamber Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 2002 | Pubmed ID: 12674769 Development and Clinical Application of an Quantitative Head-band Formed Ocular Compressor Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 2002 | Pubmed ID: 12658788 Experimental Study of Plasmid TGF-beta 1 DNA Gene Transfer with Lipofectamine into Rabbit Corneal Epithelial Cells in Vitro Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban. 2002 | Pubmed ID: 12658787 Both Donor and Recipient Origins of Smooth Muscle Cells in Vein Graft Atherosclerotic Lesions Circulation Research. Oct, 2002 | Pubmed ID: 12364395 Smooth Muscle Cells in Transplant Atherosclerotic Lesions Are Originated from Recipients, but Not Bone Marrow Progenitor Cells Circulation. Oct, 2002 | Pubmed ID: 12356638 Mechanical Stress-induced DNA Damage and Rac-p38MAPK Signal Pathways Mediate P53-dependent Apoptosis in Vascular Smooth Muscle Cells FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2002 | Pubmed ID: 12205035 Loss of P53 Accelerates Neointimal Lesions of Vein Bypass Grafts in Mice Circulation Research. Feb, 2002 | Pubmed ID: 11834713 Generation and Grafting of Tissue-engineered Vessels in a Mouse Model Mei M. Wong*1, Xuechong Hong*1, Eirini Karamariti1, Yanhua Hu1, Qingbo Xu1 1Cardiovascular Division, King's College London BHF Centre JoVE 52565 Bio-ingénierie
Generation and Grafting of Tissue-engineered Vessels in a Mouse Model Mei M. Wong*1, Xuechong Hong*1, Eirini Karamariti1, Yanhua Hu1, Qingbo Xu1 1Cardiovascular Division, King's College London BHF Centre JoVE 52565 Bio-ingénierie