Yuntao Wu Center for Infectious Disease Research, School of Systems Biology George Mason University Biography Publications Institution JoVE Articles Yuntao Wu has not added a biography. If you are Yuntao Wu and would like to personalize this page please email our Author Liaison for assistance. Publications HIV Preintegration Transcription and Host Antagonism Current HIV Research. 2023 | Pubmed ID: 37345240 Suppressing Fatty Acid Synthase by Type I Interferon and Chemical Inhibitors As a Broad Spectrum Anti-viral Strategy Against SARS-CoV-2 Acta Pharmaceutica Sinica. B. Apr, 2022 | Pubmed ID: 35251918 Development of a Hybrid Alphavirus-SARS-CoV-2 Pseudovirion for Rapid Quantification of Neutralization Antibodies and Antiviral Drugs Cell Reports Methods. Mar, 2022 | Pubmed ID: 35229082 Exosomes Originating from Infection with the Cytoplasmic Single-stranded RNA Virus Rift Valley Fever Virus (RVFV) Protect Recipient Cells by Inducing RIG-I Mediated IFN-B Response That Leads to Activation of Autophagy Cell & Bioscience. Dec, 2021 | Pubmed ID: 34953502 Prestimulation of CD2 Confers Resistance to HIV-1 Latent Infection in Blood Resting CD4 T cells IScience. Nov, 2021 | Pubmed ID: 34765923 IP-10 Promotes Latent HIV Infection in Resting Memory CD4 T Cells LIMK-Cofilin Pathway Frontiers in Immunology. 2021 | Pubmed ID: 34447368 Identification of the SHREK Family of Proteins As Broad-Spectrum Host Antiviral Factors Viruses. May, 2021 | Pubmed ID: 34064525 A Traditional Medicine, Respiratory Detox Shot (RDS), Inhibits the Infection of SARS-CoV, SARS-CoV-2, and the Influenza A Virus in Vitro Cell & Bioscience. May, 2021 | Pubmed ID: 34051873 Targeted Delivery of Lopinavir to HIV Reservoirs in the Mesenteric Lymphatic System by Lipophilic Ester Prodrug Approach Journal of Controlled Release : Official Journal of the Controlled Release Society. Jan, 2021 | Pubmed ID: 33091528 PSGL-1 Inhibits the Incorporation of SARS-CoV and SARS-CoV-2 Spike Glycoproteins into Pseudovirions and Impairs Pseudovirus Attachment and Infectivity Viruses. Dec, 2020 | Pubmed ID: 33396594 Alterations of the Gut Bacterial Microbiota in Rhesus Macaques with SIV Infection and on Short- or Long-term Antiretroviral Therapy Scientific Reports. Nov, 2020 | Pubmed ID: 33149234 Conditionally Reprogrammed Human Normal Airway Epithelial Cells at ALI: A Physiological Model for Emerging Viruses Virologica Sinica. Jun, 2020 | Pubmed ID: 32557270 PSGL-1 Restricts HIV-1 Infectivity by Blocking Virus Particle Attachment to Target Cells Proceedings of the National Academy of Sciences of the United States of America. Apr, 2020 | Pubmed ID: 32273392 SARS-CoV-2 is an Appropriate Name for the New Coronavirus Lancet (London, England). Mar, 2020 | Pubmed ID: 32151324 Understanding SARS-CoV-2-Mediated Inflammatory Responses: From Mechanisms to Potential Therapeutic Tools Virologica Sinica. Jun, 2020 | Pubmed ID: 32125642 Compensation of ACE2 Function for Possible Clinical Management of 2019-nCoV-Induced Acute Lung Injury Virologica Sinica. Jun, 2020 | Pubmed ID: 32034638 Real-time Imaging of Individual Virion-triggered Cortical Actin Dynamics for Human Immunodeficiency Virus Entry into Resting CD4 T Cells Nanoscale. Jan, 2020 | Pubmed ID: 31773115 Relationships Between HIV-Mediated Chemokine Coreceptor Signaling, Cofilin Hyperactivation, Viral Tropism Switch and HIV-Mediated CD4 Depletion Current HIV Research. 2019 | Pubmed ID: 31702526 Proteomic Profiling of HIV-1 Infection of Human CD4 T Cells Identifies PSGL-1 As an HIV Restriction Factor Nature Microbiology. May, 2019 | Pubmed ID: 30833724 Cofilin Hyperactivation in HIV Infection and Targeting the Cofilin Pathway Using an Anti-αβ Integrin Antibody Science Advances. Jan, 2019 | Pubmed ID: 30662943 Tat Controls Transcriptional Persistence of Unintegrated HIV Genome in Primary Human Macrophages Virology. 05, 2018 | Pubmed ID: 29549786 AID Recruits the RNA Exosome to Degrade HIV-1 Nascent Transcripts Through Interaction with the Tat-P-TEFb-TAR RNP Complex FEBS Letters. Jan, 2018 | Pubmed ID: 29266200 Persistence of SIV in the Brain of SIV-infected Chinese Rhesus Macaques with or Without Antiretroviral Therapy Journal of Neurovirology. Feb, 2018 | Pubmed ID: 29181724 Elevated Interferon-γ-induced Protein 10 and Its Receptor CXCR3 Impair NK Cell Function During HIV Infection Journal of Leukocyte Biology. Jul, 2017 | Pubmed ID: 28465448 Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1 Journal of Virology. Jul, 2017 | Pubmed ID: 28381571 Single-Particle Tracking of Human Immunodeficiency Virus Type 1 Productive Entry into Human Primary Macrophages ACS Nano. Apr, 2017 | Pubmed ID: 28371581 Flow Cytometry-Based Quantification of HIV-Induced T Cell Chemotactic Response Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 27271905 Real-Time Imaging of Single HIV-1 Disassembly with Multicolor Viral Particles ACS Nano. Jun, 2016 | Pubmed ID: 27253587 Therapeutic Doses of Irradiation Activate Viral Transcription and Induce Apoptosis in HIV-1 Infected Cells Virology. Nov, 2015 | Pubmed ID: 26184775 BRCA1 Functions As a Novel Transcriptional Cofactor in HIV-1 Infection Virology Journal. Mar, 2015 | Pubmed ID: 25879655 Bis-aryl Urea Derivatives As Potent and Selective LIM Kinase (Limk) Inhibitors Journal of Medicinal Chemistry. Feb, 2015 | Pubmed ID: 25621531 Chemokine Receptor CCR5 Antagonist Maraviroc: Medicinal Chemistry and Clinical Applications Current Topics in Medicinal Chemistry. 2014 | Pubmed ID: 25159165 Viral Exploitation of Actin: Force-generation and Scaffolding Functions in Viral Infection Virologica Sinica. Jun, 2014 | Pubmed ID: 24938714 HIV-1 Triggers WAVE2 Phosphorylation in Primary CD4 T Cells and Macrophages, Mediating Arp2/3-dependent Nuclear Migration The Journal of Biological Chemistry. Mar, 2014 | Pubmed ID: 24415754 Novel Anti-HIV Therapeutics Targeting Chemokine Receptors and Actin Regulatory Pathways Immunological Reviews. Nov, 2013 | Pubmed ID: 24117829 Genistein Interferes with SDF-1- and HIV-mediated Actin Dynamics and Inhibits HIV Infection of Resting CD4 T Cells Retrovirology. 2013 | Pubmed ID: 23782904 Inhibition of HIV Replication in Vitro by Clinical Immunosuppressants and Chemotherapeutic Agents Cell & Bioscience. May, 2013 | Pubmed ID: 23672887 The BET Bromodomain Inhibitor JQ1 Activates HIV Latency Through Antagonizing Brd4 Inhibition of Tat-transactivation Nucleic Acids Research. Jan, 2013 | Pubmed ID: 23087374 Involvement of LIM Kinase 1 in Actin Polarization in Human CD4 T Cells Communicative & Integrative Biology. Jul, 2012 | Pubmed ID: 23060964 HIV Gp120 is an Aberrant Chemoattractant for Blood Resting CD4 T Cells Current HIV Research. Dec, 2012 | Pubmed ID: 22954308 A Dichotomy in Cortical Actin and Chemotactic Actin Activity Between Human Memory and Naive T Cells Contributes to Their Differential Susceptibility to HIV-1 Infection The Journal of Biological Chemistry. Oct, 2012 | Pubmed ID: 22879601 The Trinity of the Cortical Actin in the Initiation of HIV-1 Infection Retrovirology. May, 2012 | Pubmed ID: 22640593 Study on the Luminescence and Energy Level of Lanthanide Ions in Lu(0.8)Sc(0.2)BO3 Host The Journal of Physical Chemistry. A. Dec, 2011 | Pubmed ID: 22026808 Spinoculation Triggers Dynamic Actin and Cofilin Activity That Facilitates HIV-1 Infection of Transformed and Resting CD4 T Cells Journal of Virology. Oct, 2011 | Pubmed ID: 21795326 LIM Kinase 1 Modulates Cortical Actin and CXCR4 Cycling and is Activated by HIV-1 to Initiate Viral Infection The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21321123 Effects of Microtubule Modulators on HIV-1 Infection of Transformed and Resting CD4 T Cells Journal of Virology. Mar, 2011 | Pubmed ID: 21209111 Control of the Differentiation of Regulatory T Cells and T(H)17 Cells by the DNA-binding Inhibitor Id3 Nature Immunology. Jan, 2011 | Pubmed ID: 21131965 Chemokine Control of HIV-1 Infection: Beyond a Binding Competition Retrovirology. 2010 | Pubmed ID: 20942936 Development of a Nonintegrating Rev-dependent Lentiviral Vector Carrying Diphtheria Toxin A Chain and Human TRAF6 to Target HIV Reservoirs Gene Therapy. Sep, 2010 | Pubmed ID: 20410930 Chemokine Coreceptor Signaling in HIV-1 Infection and Pathogenesis PLoS Pathogens. Dec, 2009 | Pubmed ID: 20041213 The HIV Envelope but Not VSV Glycoprotein is Capable of Mediating HIV Latent Infection of Resting CD4 T Cells PLoS Pathogens. Oct, 2009 | Pubmed ID: 19851458 Chemokine Receptor Signaling and HIV Infection Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19763976 Measurement of Human Immunodeficiency Virus Type 1 Preintegration Transcription by Using Rev-dependent Rev-CEM Cells Reveals a Sizable Transcribing DNA Population Comparable to That from Proviral Templates Journal of Virology. Sep, 2009 | Pubmed ID: 19553325 The Co-receptor Signaling Model of HIV-1 Pathogenesis in Peripheral CD4 T Cells Retrovirology. 2009 | Pubmed ID: 19409100 Cofilin Activation in Peripheral CD4 T Cells of HIV-1 Infected Patients: a Pilot Study Retrovirology. 2008 | Pubmed ID: 18928553 HIV Envelope-CXCR4 Signaling Activates Cofilin to Overcome Cortical Actin Restriction in Resting CD4 T Cells Cell. Sep, 2008 | Pubmed ID: 18775311 The Second Chance Story of HIV-1 DNA: Unintegrated? Not a Problem! Retrovirology. 2008 | Pubmed ID: 18613958 Selective Killing of HIV-1-positive Macrophages and T Cells by the Rev-dependent Lentivirus Carrying Anthrolysin O from Bacillus Anthracis Retrovirology. 2008 | Pubmed ID: 18439272 Human Macrophages Support Persistent Transcription from Unintegrated HIV-1 DNA Virology. Mar, 2008 | Pubmed ID: 18054979 Endogenous TGF-beta Activation by Reactive Oxygen Species is Key to Foxp3 Induction in TCR-stimulated and HIV-1-infected Human CD4+CD25- T Cells Retrovirology. 2007 | Pubmed ID: 17688698 Rev-dependent Indicator T Cell Line Current HIV Research. Jul, 2007 | Pubmed ID: 17627502 Rev-dependent Lentiviral Expression Vector Retrovirology. 2007 | Pubmed ID: 17286866 No Single Homologous Repeat Region is Essential for DNA Replication of the Baculovirus Autographa Californica Multiple Nucleopolyhedrovirus The Journal of General Virology. Jan, 2007 | Pubmed ID: 17170443 HIV-1 Gene Expression: Lessons from Provirus and Non-integrated DNA Retrovirology. 2004 | Pubmed ID: 15219234 Early Transcription from Nonintegrated DNA in Human Immunodeficiency Virus Infection Journal of Virology. Oct, 2003 | Pubmed ID: 12970422 Gene Transcription in HIV Infection Microbes and Infection / Institut Pasteur. Sep, 2003 | Pubmed ID: 12941394 Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research Linda Chilin1, Brian Hetrick1, Yuntao Wu1 1Center for Infectious Disease Research, School of Systems Biology, George Mason University JoVE 65793 Immunologie et Infection Specific Marking of HIV-1 Positive Cells using a Rev-dependent Lentiviral Vector Expressing the Green Fluorescent Protein JoVE 2198 Immunologie et Infection
Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research Linda Chilin1, Brian Hetrick1, Yuntao Wu1 1Center for Infectious Disease Research, School of Systems Biology, George Mason University JoVE 65793 Immunologie et Infection
Specific Marking of HIV-1 Positive Cells using a Rev-dependent Lentiviral Vector Expressing the Green Fluorescent Protein JoVE 2198 Immunologie et Infection