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A Standardized Workflow for Hyperpolarized 129Xe MRI to Study Pulmonary Function

November 21st, 2023
1, 1,2, 2, 2, 3, 1,2,4
1Department of Biomedical Engineering, University of Virginia, 2Department of Radiology and Medical Imaging, University of Virginia, 3Department of Medicine, University of Virginia, 4Department of Physics, University of Virginia

Summary
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Hyperpolarized 129Xe magnetic resonance imaging (MRI) is a method for studying regionally resolved aspects of pulmonary function. This work presents an end-to-end standardized workflow for hyperpolarized 129Xe MRI of lung ventilation, with specific attention to pulse sequence design, 129Xe dose preparation, scan workflow, and best practices for subject safety monitoring.

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