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JoVE Journal Cancer Research

Pancreas Tumor Implantation in Mice

Pancreas Tumor Implantation in Mice

Murine Pancreatic Imaging Using Implanted Stabilized Window

Article DOI: 10.3791/200454-v • 01:50 min • October 6th, 2023

October 6th, 2023 •

Jakeb Petersen*^1,2,3, Wei Du*^4,5, Christian Adkisson^1,4, Claudia Gravekamp^6,7, Maja H. Oktay^2,3,4,7,8,9, John Condeelis^{1,3,4,7,8,9,10}, Nicole C. Panarelli^2,3,7, John C. McAuliffe^1,2,3,7,8, David Entenberg^2,3,4,7,8,9

¹Department of Surgery, Einstein College of Medicine / Montefiore Medical Center, ²Department of Pathology, Einstein College of Medicine / Montefiore Medical Center, ³Integrated Imaging Program for Cancer Research, Einstein College of Medicine / Montefiore Medical Center, ⁴Department of Anatomy and Structural Biology, Einstein College of Medicine / Montefiore Medical Center, ⁵Breast Center, Peking University People's Hospital, ⁶Department of Microbiology & Immunology, Einstein College of Medicine / Montefiore Medical Center, ⁷Montefiore Einstein Cancer Center, Einstein College of Medicine / Montefiore Medical Center, ⁸Cancer Dormancy and Tumor Microenvironment Institute, Albert Einstein College of Medicine / Montefiore Medical Center, ⁹Gruss-Lipper Biophotonics Center, Einstein College of Medicine / Montefiore Medical Center, ¹⁰Department of Cell Biology, Einstein College of Medicine / Montefiore Medical Center

* These authors contributed equally

Tags

Stabilized Window Intravital Imaging Murine Pancreas Pancreas Physiology Pancreatitis Pancreatic Adenocarcinoma High-resolution Imaging Real-time Observation Cell Dynamics SWIP Implantation Process Healthy Pancreas Acute Pancreatitis Pancreatic Tumors Genetically Labeled Cells Fluorescent Dyes Single-cell Dynamics Subcellular Dynamics Collective Migration Serial Imaging Tumor Cell Migration Metastatic Burden PDAC

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