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JoVE Journal Neuroscience
Mitochondrial Morphology Analysis by Immunohistochemistry on Paraffin-Embedded Brain Slices from α-Synuclein Pre-Formed Fibrils (PFF)-Injected Mice
 

Mitochondrial Morphology Analysis by Immunohistochemistry on Paraffin-Embedded Brain Slices from α-Synuclein Pre-Formed Fibrils (PFF)-Injected Mice

An In Situ Immunostaining Protocol for Parkinson's Disease Study

Article DOI: 10.3791/201001-v • 04:21 min • June 23rd, 2023
June 23rd, 2023 •
*1, *1, 1, 1, 1, 1, 1,2,3,4
1Achucarro Basque Center for Neuroscience, 2Department of Neuroscience, University of the Basque Country (UPV/EHU), 3Ikerbasque - Basque Foundation for Science, 4Oxford Parkinson’s Disease Centre and Department of Physiology, Anatomy and Genetics, University of Oxford
* These authors contributed equally

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Histological Examination Mitochondrial Morphology Parkinson's Disease Model Mitochondria Energy Metabolism Neurons Mitochondrial Dysfunction Neurological Disorders Shape And Organization Of Mitochondrial Network Immunostaining VDAC1 Protein Image Analysis Neurodegenerative Disorders α-synuclein Aggregates Parkinson's Disease Pathology Substantia Nigra Pars Compacta Dopaminergic Neurons PS129 Lesions Mitochondrial Fragmentation
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