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Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
 

Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling

Article DOI: 10.3791/2712-v • 12:29 min • May 30th, 2011
May 30th, 2011 •
1,2, 1,3, 1, 1, 3, 1, 3, 3, 1,3
1Medicine, University of California San Diego - UCSD, 2Bioengineering, University of California San Diego - UCSD, 3Radiology, University of California San Diego - UCSD

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résumé
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A MR imaging method to study the distribution of pulmonary blood flow under a variety of physiological conditions, in this case exposure to three different inspired oxygen concentrations: hypoxia, normoxia, and hyperoxia, is described. This technique utilizes human pulmonary physiology research techniques in an MR scanning environment.

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Magnetic Resonance Imaging Pulmonary Perfusion Calibrated Arterial Spin Labeling MR Imaging Method Spatial Distribution Pulmonary Blood Flow Healthy Subjects Normoxia Hypoxia Hyperoxia Physiological Responses MR Scan Environment Sagittal Slice Right Lung Functional Residual Capacity Arterial Spin Labeling Sequence Multi-echo Fast Gradient Echo Sequence Density-normalized Perfusion Voxel Pneumatic Switching Valve Facemask Non-rebreathing Valve Oxygen Concentrations Inspired Gas Tubing Metabolic Cart Expiratory Gas Oxygen Consumption Carbon Dioxide Production Respiratory Exchange Ratio Respiratory Frequency Tidal Volume Heart Rate Oxygen Saturation
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