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Bioengineering

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JoVE Journal Bioengineering
Engineering Skeletal Muscle Tissues from Murine Myoblast Progenitor Cells and Application of Electrical Stimulation
 

Engineering Skeletal Muscle Tissues from Murine Myoblast Progenitor Cells and Application of Electrical Stimulation

Article DOI: 10.3791/4267-v • 08:38 min • March 19th, 2013
March 19th, 2013 •
1, 1, 1, 1, 1, 1
1Department of Biomedical Engineering, Soft Tissue Biomechanics and Engineering, Eindhoven University of Technology, The Netherlands

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Engineered muscle tissue has great potential in regenerative medicine, as disease model and also as an alternative source for meat. Here we describe the engineering of a muscle construct, in this case from mouse myoblast progenitor cells, and the stimulation by electrical pulses.

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Engineering Skeletal Muscle Tissues Murine Myoblast Progenitor Cells Electrical Stimulation Disease Model Regenerative Medicine Meat Alternative 3D Muscle Constructs Biochemical Factors Stem Cells Physical Factors Cell-populated Hydrogel Constructs Collagen/Matrigel Muscle Ligaments Alternative Cell Lines L6 Rat Myoblasts Neonatal Muscle Derived Progenitor Cells Adult Muscle Tissues Induced Pluripotent Stem Cells (iPS Cells) Cell Contractility
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