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Chemistry

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Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
 

Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Article DOI: 10.3791/50890-v 15:33 min October 29th, 2013
October 29th, 2013

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résumé

This video will illustrate a rapid, efficient method to methacrylate poly(ethylene glycol), enabling chain polymerizations and hydrogel synthesis. It will demonstrate how to similarly introduce methacrylamide functionalities into peptides, detail common analytical methods to assess functionalization efficiency, provide suggestions for troubleshooting and advanced modifications, and demonstrate typical hydrogel characterization techniques.

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Keywords: Poly(ethylene Glycol) PEG PEGDM Microwave-assisted Functionalization Methacrylation On-resin Peptide Functionalization Methacrylamide Hydrogel Formation Drug Delivery Regenerative Medicine Analytical Methods NMR MALDI-ToF Hydrogel Properties Mesh Size Stiffness Drug Release
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