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JoVE Journal Neuroscience
In vivo imaging di Optic Nerve Fiber Integrity by MRI Contrast-Enhanced nei topi
 
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In vivo imaging di Optic Nerve Fiber Integrity by MRI Contrast-Enhanced nei topi

Article DOI: 10.3791/51274-v • 11:38 min • July 22nd, 2014
July 22nd, 2014 •
*1, *2, 3, 3, 1, 2, 1, 2
1Hans Berger Department of Neurology, Jena University Hospital, 2Immunology, Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, 3Institute of Diagnostic and Interventional Radiology, Medical Physics Group, Jena University Hospital
* These authors contributed equally

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Questo video illustra un metodo, utilizzando un clinico 3 scanner T, per contrasto-enhanced RM del mouse ingenua proiezione visiva e per studi ripetitivi e longitudinali in vivo di degenerazione del nervo ottico associati a lesioni acute ottico schiacciamento del nervo e la degenerazione del nervo ottico cronica topi knock-out (p50 KO).

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Neuroscienze Numero 89 manganese-enhanced MRI mouse retino-tectal proiezione sistema visivo neurodegenerazione lesioni del nervo ottico NF-kB
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