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Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
 

Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation

Article DOI: 10.3791/52909-v • 08:12 min • July 15th, 2015
July 15th, 2015 •
1,2, 1, 1, 1, 1, 3, 4, 5, 5, 1, 1, 6,7, 2, 1
1Multi Organ Transplant Program, Department of Surgery, Toronto General Hospital, 2Division of Nephrology, The Hospital for Sick Children, Toronto, 3Department of General, Visceral & Transplant Surgery, University Medical Center Mainz, 4Department of Abdominal, Vascular & Transplant Surgery, Merheim Medical Center Cologne, 5Laboratory Medicine & Pathobiology, Toronto General Hospital, 6Departments of Surgery (Urology) & Physiology, The Hospital for Sick Children, Toronto, 7Developmental & Stem Cell Biology, The Hospital for Sick Children, Toronto

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The severe organ shortage has resulted in increased use of marginal kidney grafts for transplantation. This has triggered interest in alternative storage methods, since marginal grafts especially tolerate cold storage poorly. The technique of normothermic ex vivo kidney perfusion (NEVKP) represents a novel preservation method for kidney grafts prior to  transplantation.

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Normothermic Ex Vivo Kidney Perfusion Preservation Kidney Grafts Transplantation Organ Shortage Marginal Kidney Grafts Cold Storage Preservation Injury Delayed Graft Function Normothermic Preservation Methods Normothermic Organ Perfusion Experimental Trials Clinical Trials Lung Perfusion Liver Perfusion Kidney Perfusion Cold Ischemic Injury Organ Assessment Organ Repair Kidney Retrieval Preservation Techniques Isolated Ex Vivo Normothermic Kidney Perfusion (NEVKP) Porcine Model Surgical Techniques Perfusion Solution Circuit Setup Assessment Options
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