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A Novel Microsurgical Model for Heterotopic, En Bloc Chest Wall, Thymus, and Heart Transplantation in Mice
 

A Novel Microsurgical Model for Heterotopic, En Bloc Chest Wall, Thymus, and Heart Transplantation in Mice

Article DOI: 10.3791/53442-v • 12:24 min • January 23rd, 2016
January 23rd, 2016 •
*1, *1, *1, 1, 2,3, 4, 1,5,6, 1,5,6
1Johns Hopkins University School of Medicine, 2Burn and Complex Wound Center, 3Section of Plastic and Reconstructive Surgery, University of Chicago Medical Center, 4Division of Plastic, Reconstructive, and Maxillofacial Surgery, R Adams Cowley Shock Trauma Center, 5Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, 6Vascularized Composite Allotransplantation (VCA) Lab, Johns Hopkins University School of Medicine
* These authors contributed equally

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résumé
Automatic Translation

To study combined solid organ and vascularized composite allotransplantation, we describe a novel heterotopic en bloc chest wall, thymus, and heart transplant model in mice using a cervical non-suture cuff technique.

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Novel Microsurgical Model Heterotopic Transplantation En Bloc Transplantation Chest Wall Transplantation Thymus Transplantation Heart Transplantation Mice Murine Model Solid Organ Transplant Vascularized Composite Allotransplantation Immune Tolerance Allograft Survival Vascularized Hematopoietic Tissue Primary Lymphoid Tissue Reconstructive Transplantation Vascularized Bone Marrow Thymus Heart Immunologically Versatile Mass Model System Tissue Defects Long-term Survival Clinical Translation Plastic And Reconstructive Surgery Department Johns Hopkins University
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