JoVE Journal
Immunology and Infection
Immunology and Infection
Ce contenu est en libre accès.
Chapitres
résumé
This article describes the high-throughput assay that has been successfully established to screen large libraries of small molecules for their potential ability to manipulate cellular levels of cyclic di-GMP in Pseudomonas aeruginosa, providing a new powerful tool for antibacterial drug discovery and compound testing.