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JoVE Journal Genetics
-Methyl-bindende DNA capture Sequencing for Patient Tissues
 
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-Methyl-bindende DNA capture Sequencing for Patient Tissues

Article DOI: 10.3791/54131-v • 08:40 min • October 31st, 2016
October 31st, 2016 •
1, 1, 1, 1, 2, 2, 1, 1
1Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, 2Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio

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Hier presenteren we een protocol om het gehele genoom DNA-methylatie in grootschalige klinische patiënt screening studies met behulp van de Methyl-bindende DNA Capture sequencing (MBDCap-seq of MBD-volgende) technologie en de daaropvolgende bioinformatica analyse pijplijn te onderzoeken.

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Genetics DNA-methylatie Sequencing MBD-seq Bio-informatica Differential methylatie Epigenetica.
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