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A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies
 

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies

Article DOI: 10.3791/55571-v • 06:53 min • July 4th, 2017
July 4th, 2017 •
1, 2, 2, 3, 3, 4
1Department of Bioengineering, Department of Orthopedics, University of Colorado Anschutz Medical Campus, 2Department of Orthopedics, University of Colorado Anschutz Medical Campus, 3Department of Chemical & Biological Engineering, Colorado School of Mines, 4Department of Orthopedics, Gates Center for Regenerative Medicine, University of Colorado Anschutz Medical Campus

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The growth plate is a cartilaginous region in children's long bones where longitudinal growth occurs. When injured, bony tissue can form and impair growth. We describe a rat model of growth plate injury that leads to bony repair tissue, allowing the study of repair mechanisms and growth plate regeneration strategies.

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Rat Tibial Growth Plate Injury Model Repair Mechanisms Growth Plate Regeneration Strategies Drill-hole Growth Plate Injury Evaluation Of Growth Plate Repair Strategies Bony Repair Tissue Formation Novel Treatments For Growth Plate Regeneration Clinical Injuries Treatment Of Growth Plate Injuries Difficulty In Measuring And Estimating Drill Depth Hind Leg Hair Removal Calipers For Tibial Length Measurement Disinfecting Procedure
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