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JoVE Journal Neuroscience
Neurobehavioral Assessments in a Mouse Model of Neonatal Hypoxic-ischemic Brain Injury
 

Neurobehavioral Assessments in a Mouse Model of Neonatal Hypoxic-ischemic Brain Injury

Article DOI: 10.3791/55838-v • 08:32 min • November 24th, 2017
November 24th, 2017 •
1,2, 1, 1,2, 1,2, 1,2, 1,3, 1,5, 1,2,4,5
1Department and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, 2Brain Korea 21 PLUS Project for Medical Science, Yonsei University, 3Department of Rehabilitation Medicine, Yonsei University Wonju College of Medicine, 4Rehabilitation Institute of Neuromuscular Disease, Yonsei University College of Medicine, 5Graduate Program of NanoScience and Technology, Yonsei University

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We performed unilateral carotid artery occlusion on postnatal day 7-10 CD-1 mouse pups to create a neonatal hypoxic-ischemic (HI) model and investigated the effects of HI brain injury. We studied neurobehavioral functions in these mice compared to non-operated normal mice.

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Neurobehavioral Assessments Mouse Model Neonatal Hypoxic-ischemic Brain Injury Cognitive Testing Motor Testing Brain Damage Cerebral Palsy Neonatal Strokes Surgical Procedure Carotid Artery Ligation Anesthesia Recovery Chamber
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