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Bioengineering

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JoVE Journal Bioengineering
Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
 

Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model

Article DOI: 10.3791/55928-v • 07:12 min • September 28th, 2017
September 28th, 2017 •
1, 1, 2,3,4, 1,2,3,5, 1,2,3,4,5, 1,2,3,4
1Skeletal Biotech Laboratory, Hebrew University-Hadassah Faculty of Dental Medicine, 2Department of Surgery, Cedars-Sinai Medical Center, 3Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 4Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, 5Department of Orthopedics, Cedars-Sinai Medical Center

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The goal of this protocol is to generate a nude rat osteoporosis-related vertebral compression fracture model that can be longitudinally evaluated in vivo using a semiautomated microcomputed tomography-based quantitative structural analysis.

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Keywords: Semiautomated Longitudinal Microcomputed Tomography Quantitative Structural Analysis Nude Rat Osteoporosis Vertebral Fracture Model Glial Regenerative Medicine Bone Regeneration In Vivo Anesthesia Surgical Procedure Abdominal Cavity Lumbar Spine Vertebral Bodies
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