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Neuroscience

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JoVE Journal Neuroscience
Adult Mouse DRG Explant and Dissociated Cell Models to Investigate Neuroplasticity and Responses to Environmental Insults Including Viral Infection
 

Adult Mouse DRG Explant and Dissociated Cell Models to Investigate Neuroplasticity and Responses to Environmental Insults Including Viral Infection

Article DOI: 10.3791/56757-v • 09:23 min • March 9th, 2018
March 9th, 2018 •
1, 1, 2
1Department of Anatomy, Chicago College of Osteopathic Medicine (CCOM), Midwestern University, 2Department of Microbiology and Immunology, Chicago College of Osteopathic Medicine (CCOM), Midwestern University

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résumé
Automatic Translation

In this report, the advantages of organotypic cultures and dissociated primary cultures of mouse-derived dorsal root ganglia are highlighted to investigate a wide range of mechanisms associated with neuron-glial interaction, neuroplasticity, neuroinflammation, and response to viral infection.

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Keywords: Dorsal Root Ganglia DRG Explant Dissociated Cell Model Neuroplasticity Neuroinflammation Viral Infection Spinal Cord Peripheral Nerve Intervertebral Foramen Primary Cell Culture
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