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Cancer Research

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A Comprehensive Procedure to Evaluate the In Vitro Performance of the Putative Hemangioblastoma Neovascularization Using the Spheroid Sprouting Assay
 

A Comprehensive Procedure to Evaluate the In Vitro Performance of the Putative Hemangioblastoma Neovascularization Using the Spheroid Sprouting Assay

Article DOI: 10.3791/57183-v 08:26 min April 12th, 2018
April 12th, 2018

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résumé

This paper presents a comprehensive procedure to evaluate in vitro whether classic tumor angiogenesis exists in hemangioblastomas (HBs) and its role in HBs. The results highlight the complexity of HB-neovascularization and suggest that this common form of angiogenesis is only a complementary mechanism in the HB-neovascularization.

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Keywords: Spheroid Sprouting Assay Hemangioblastoma Neovascularization Tumor Angiogenesis Vasculogenesis HUVEC ShRNA Lentiviral Vector Endothelial Cell Angiogenesis Tumor Vasculogenic Mimicry
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