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JoVE Journal Neuroscience
Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats
 

Microdialysis of Excitatory Amino Acids During EEG Recordings in Freely Moving Rats

Article DOI: 10.3791/58455-v • 08:47 min • November 8th, 2018
November 8th, 2018 •
1, 1, 1, 1, 1, 1, 1
1Department of Medical Sciences, Section of Pharmacology, Neuroscience Center, University of Ferrara and National Institute of Neuroscience

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Here, we describe a method for in vivo microdialysis to analyze aspartate and glutamate release in the ventral hippocampus of epileptic and non-epileptic rats, in combination with EEG recordings. Extracellular concentrations of aspartate and glutamate may be correlated with the different phases of the disease.

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Keywords: Microdialysis Excitatory Amino Acids EEG Freely Moving Rats Neurotransmitter Release Neurological Diseases Faraday Cage EEG Amplifier EEG Software EEG Signal Tethered EEG Recording System Amplification Factor Ringer's Solution FEP Tubing Guide Cannula Plexiglass Cylinder
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