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Implantation of Human-Sized Coronary Stents into Rat Abdominal Aorta Using a Trans-Femoral Access
 

Implantation of Human-Sized Coronary Stents into Rat Abdominal Aorta Using a Trans-Femoral Access

Article DOI: 10.3791/61442-v • 05:04 min • November 19th, 2020
November 19th, 2020 •
*1, *1, 1, 1, 1, *1,2,3, *1
1Division of Cardiology, Angiology, and Critical Care, University Hospital RWTH Aachen, 2Department for Operative Intensive Medicine, University Hospital RWTH Aachen, 3Institute for Pathology "Victor Babes"
* These authors contributed equally

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résumé
Automatic Translation

This protocol describes the implantation of human coronary stents into the abdominal aorta of rats with an apoE-/- background using a trans-femoral access. Compared with other animal models, murine models carry the advantages of high throughput, reproducibility, ease of handling and housing, and a broad availability of molecular markers.

Tags

Human-sized Coronary Stents Rat Abdominal Aorta Trans-femoral Access Animal Model Vascular Pathology Minimally Invasive Highly Reproducible Operative Experience Clinical Tools Pathology Diagnostic Tools Optical Coherence Tomography Histological Analysis Anesthetized Adult Rat Pedal Reflex Heating Pad Supine Position Medical Tape Ointment Groin And Lower Abdomen Sterilize Skin Povidone Iodine Solution Implantation Of Stent Medial Incision Right Groin Skin And Underlying Fascia Connective Tissue 4-0 Silk Suture
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