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A Model of Cardiac Remodeling Through Constriction of the Abdominal Aorta in Rats
 

A Model of Cardiac Remodeling Through Constriction of the Abdominal Aorta in Rats

Article DOI: 10.3791/54818-v • 07:31 min • December 2nd, 2016
December 2nd, 2016 •
1, 2,3, 4, 1,5, 1
1Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, 2Division of Pulmonary and Critical Care Medicine, Mackay Memorial Hospital, 3Mackay Medicine, Nursing and Management College, 4School of Medicine, National Taiwan University, 5Department of Internal Medicine, National Taiwan University Hosptial

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résumé
Automatic Translation

A rat model of abdominal aortic constriction that induces cardiac hypertrophy and remodeling is described. An efficient, highly-reproducible, and minimally-invasive method is used to provide a simple yet useful platform for research in myocardial hypertrophy and dysfunction.

Tags

Cardiac Remodeling Abdominal Aorta Constriction Rats Surgical Procedure Myocardial Hypertrophy Remodeling Dysfunction Cardiovascular Field Signaling Therapeutic Targets Hypertensive Heart Disease Minimally Invasive Method Simple Surgical Techniques Reproducible Results Therapy Pressure Overload Heart Failure Syringe Needle Honing Stone Pliers Recovery Cage Surgical Instruments Rat Care And Preparation
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