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Developmental Biology

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JoVE Journal Developmental Biology
Human Ex vivo Wound Model and Whole-Mount Staining Approach to Accurately Evaluate Skin Repair
 

Human Ex vivo Wound Model and Whole-Mount Staining Approach to Accurately Evaluate Skin Repair

Article DOI: 10.3791/62326-v • 07:32 min • February 17th, 2021
February 17th, 2021 •
1, 1, 1, 1
1Centre for Atherothrombosis and Metabolic Disease, Hull York Medical School, University of Hull

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Here we demonstrate an optimized technique for assessing wound repair using ex vivo human skin combined with a whole-mount staining approach. This methodology provides a pre-clinical platform for the evaluation of potential wound therapies.

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Keywords: Ex Vivo Human Skin Wound Model Whole-mount Staining Skin Repair Wound Assessment Skin Explant Wound Healing Skin Fixative Fluorescent Staining
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