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En gnagermodell av Ross-operasjonen
 
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En gnagermodell av Ross-operasjonen: Syngeneic Pulmonary Artery Graft Implantation i en systemisk posisjon

Article DOI: 10.3791/63179-v • 11:20 min • April 1st, 2022
April 1st, 2022 •
*1, *1, 2, 2, 2, 1,3, 1
1Pediatric and Congenital Cardiac Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, 2Pediatric Cardiology Unit, Departments of Women’s and Children’s Health, University of Padua, 3Labatt Family Heart Centre, Department of Cardiovascular Surgery, The Hospital for Sick Children, University of Toronto
* These authors contributed equally

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Vi demonstrerer hvordan man etablerer en murinmodell av lungerotimplantasjon i den synkende aorta for å simulere Ross-prosedyren. Denne modellen muliggjør mellomlang/langsiktig evaluering av pulmonal autograft-ombygging i en systemisk posisjon, som representerer grunnlaget for å utvikle terapeutiske strategier for å fremme tilpasningen.

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