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Immunology and Infection

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JoVE Journal Immunology and Infection
Rose Bengal-Mediated Photodynamic Therapy to Inhibit Candida albicans
 

Rose Bengal-Mediated Photodynamic Therapy to Inhibit Candida albicans

Article DOI: 10.3791/63558-v • 04:48 min • March 24th, 2022
March 24th, 2022 •
*1,2, *3,4, 5, 3,6, 7, 7, 3, 3,8,9
1Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, 2Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 3Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, 4Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, 5Department of Dermatology, Fu Jen Catholic University Hospital, Fu Jen Catholic University, 6Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung University, 7School of Medicine, National Cheng Kung University, 8Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, 9Center of Applied Nanomedicine, National Cheng Kung University
* These authors contributed equally

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résumé
Automatic Translation

The growing incidence of drug-resistant Candida albicans is a serious health issue worldwide. Antimicrobial photodynamic therapy (aPDT) may offer a strategy to fight against drug-resistant fungal infections. The present protocol describes Rose bengal-mediated aPDT efficacy on a multidrug-resistant C. albicans strain in vitro.

Tags

Rose Bengal-Mediated Photodynamic Therapy Candida Albicans Microorganisms Cells LED Arrangement PDT 96-well Plate 384-well Plate Fungal Keratitis Green LEDs Fluence Rate Light Power Meter Temperature Control Electric Fan Candida Albicans Culture YPD Medium Log Growth Phase
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