Hong-Fen Guo Department of Pediatrics Memorial Sloan Kettering Cancer Center Biography Publications Institution JoVE Articles Hong-Fen Guo has not added a biography. If you are Hong-Fen Guo and would like to personalize this page please email our Author Liaison for assistance. Publications Identification of Immunotherapy and Radioimmunotherapy Targets on Desmoplastic Small Round Cell Tumors Frontiers in Oncology. 2023 | Pubmed ID: 37091153 Targeting Tumor Vasculature to Improve Antitumor Activity of T Cells Armed Ex Vivo with T Cell Engaging Bispecific Antibody Journal for Immunotherapy of Cancer. Mar, 2023 | Pubmed ID: 36990507 Intraperitoneal Pretargeted Radioimmunotherapy for Colorectal Peritoneal Carcinomatosis Molecular Cancer Therapeutics. Jan, 2022 | Pubmed ID: 34667111 Novel Potent Anti-STEAP1 Bispecific Antibody to Redirect T Cells for Cancer Immunotherapy Journal for Immunotherapy of Cancer. Sep, 2021 | Pubmed ID: 34497115 T Cell Engaging Bispecific Antibodies Targeting CD33 IgV and IgC Domains for the Treatment of Acute Myeloid Leukemia Journal for Immunotherapy of Cancer. May, 2021 | Pubmed ID: 34035113 Potent Antitumor Effect of T Cells Armed with Anti-GD2 Bispecific Antibody Pediatric Blood & Cancer. Jul, 2021 | Pubmed ID: 33844437 A Self-Assembling and Disassembling (SADA) Bispecific Antibody (BsAb) Platform for Curative Two-step Pretargeted Radioimmunotherapy Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2021 | Pubmed ID: 32958698 Overcoming Leukemia Heterogeneity by Combining T Cell Engaging Bispecific Antibodies Journal for Immunotherapy of Cancer. Nov, 2020 | Pubmed ID: 33239418 Alpha Radioimmunotherapy Using Ac-proteus-DOTA for Solid Tumors - Safety at Curative Doses Theranostics. 2020 | Pubmed ID: 33052220 Interdomain Spacing and Spatial Configuration Drive the Potency of IgG-[L]-scFv T Cell Bispecific Antibodies Science Translational Medicine. Mar, 2020 | Pubmed ID: 32161106 An -Acetylgalactosamino Dendron-Clearing Agent for High-Therapeutic-Index DOTA-Hapten Pretargeted Radioimmunotherapy Bioconjugate Chemistry. Mar, 2020 | Pubmed ID: 31891487 Theranostic Pretargeted Radioimmunotherapy of Internalizing Solid Tumor Antigens in Human Tumor Xenografts in Mice: Curative Treatment of HER2-positive Breast Carcinoma Theranostics. 2018 | Pubmed ID: 30429889 Development of a Tetravalent Anti-GPA33/Anti-CD3 Bispecific Antibody for Colorectal Cancers Molecular Cancer Therapeutics. Oct, 2018 | Pubmed ID: 30082472 Curative Multicycle Radioimmunotherapy Monitored by Quantitative SPECT/CT-Based Theranostics, Using Bispecific Antibody Pretargeting Strategy in Colorectal Cancer Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Nov, 2017 | Pubmed ID: 28705917 Theranostic Pretargeted Radioimmunotherapy of Colorectal Cancer Xenografts in Mice Using Picomolar Affinity ⁸⁶Y- or ¹⁷⁷Lu-DOTA-Bn Binding ScFv C825/GPA33 IgG Bispecific Immunoconjugates European Journal of Nuclear Medicine and Molecular Imaging. May, 2016 | Pubmed ID: 26596724 Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3 The Journal of Biological Chemistry. Dec, 2015 | Pubmed ID: 26487718 A Distinct Gene Expression Signature Characterizes Human Neuroblastoma Cancer Stem Cells Stem Cell Research. Sep, 2015 | Pubmed ID: 26342562 Alteration of Electrostatic Surface Potential Enhances Affinity and Tumor Killing Properties of Anti-ganglioside GD2 Monoclonal Antibody Hu3F8 The Journal of Biological Chemistry. May, 2015 | Pubmed ID: 25851904 Preclinical Evaluation of Multistep Targeting of Diasialoganglioside GD2 Using an IgG-scFv Bispecific Antibody with High Affinity for GD2 and DOTA Metal Complex Molecular Cancer Therapeutics. Jul, 2014 | Pubmed ID: 24944121 In Silico Driven Redesign of a Clinically Relevant Antibody for the Treatment of GD2 Positive Tumors PloS One. 2013 | Pubmed ID: 23696816 Interstitial Infusion of Glioma-targeted Recombinant Immunotoxin 8H9scFv-PE38 Molecular Cancer Therapeutics. Apr, 2010 | Pubmed ID: 20371725 MicroRNA MiR-29 Modulates Expression of Immunoinhibitory Molecule B7-H3: Potential Implications for Immune Based Therapy of Human Solid Tumors Cancer Research. Aug, 2009 | Pubmed ID: 19584290 Radioimmunotargeting of Human Rhabdomyosarcoma Using Monoclonal Antibody 8H9 Cancer Biotherapy & Radiopharmaceuticals. Oct, 2005 | Pubmed ID: 16248769 Characteristics of Stem Cells from Human Neuroblastoma Cell Lines and in Tumors Neoplasia (New York, N.Y.). 2004 | Pubmed ID: 15720811 Anti-idiotypic Antibody Facilitates ScFv Chimeric Immune Receptor Gene Transduction and Clonal Expansion of Human Lymphocytes for Tumor Therapy Hybridoma and Hybridomics. Aug, 2003 | Pubmed ID: 14511566 Anti-idiotypic Antibody As the Surrogate Antigen for Cloning ScFv and Its Fusion Proteins Hybridoma and Hybridomics. Dec, 2002 | Pubmed ID: 12573107 Antigen-dependent CD28 Signaling Selectively Enhances Survival and Proliferation in Genetically Modified Activated Human Primary T Lymphocytes The Journal of Experimental Medicine. Aug, 1998 | Pubmed ID: 9705944 Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells Madelyn Espinosa-Cotton1, Hong-Fen Guo1, Nai-Kong V. Cheung1 1Department of Pediatrics, Memorial Sloan Kettering Cancer Center JoVE 64390 Ricerca sul cancro
Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells Madelyn Espinosa-Cotton1, Hong-Fen Guo1, Nai-Kong V. Cheung1 1Department of Pediatrics, Memorial Sloan Kettering Cancer Center JoVE 64390 Ricerca sul cancro